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1. 发明授权

US08771329B2 Methods and apparatus for enhancing vascular access in an appendage to enhance therapeutic and interventional procedures 有权
标题翻译：用于增强附件中血管通路以增强治疗和介入程序的方法和装置
公开(公告)号：US08771329B2
公开(公告)日：2014-07-08
申请号：US12987015
申请日：2011-01-07
申请人： Scott A. Christensen , John Roy Kane , Nathan Hamilton
发明人： Scott A. Christensen , John Roy Kane , Nathan Hamilton
IPC分类号： A61F7/00 , A61F7/08
CPC分类号： A61F7/02 , A61B2017/00084 , A61F2007/0034 , A61F2007/0035 , A61F2007/0036 , A61F2007/0043 , A61F2007/0045 , A61F2007/0054 , A61F2007/0095 , A61F2007/0239 , A61F2007/0273 , A61F2007/0274
摘要： Embodiments of the invention disclosed herein generally include methods and/or devices for increasing blood flow, controlling the vasodilatation of a patient's vascular structure, regulating the temperature of a portion of a mammal, and for improving various interventional procedures and/or therapeutic techniques. The device may also include one or more access ports, or apertures, that allow access to portions of the mammal's extremity to allow interventional type medical devices, therapeutic devices, surgical support equipment or patient monitoring devices to have access to the extremity on which a body element is disposed. The device may also be configured to allow other supporting components, which may include IV or other catheters, a means of accessing to a portion of the extremity positioned inside the temperature regulating device. In one configuration the device comprises flexible materials that are adapted to conform to the surface of the extremity disposed in the device when a vacuum pressure is applied to an internal region of the device.
摘要翻译：本文公开的本发明的实施方案通常包括用于增加血流量，控制患者血管结构的血管扩张，调节哺乳动物的一部分的温度以及改善各种介入手术和/或治疗技术的方法和/或装置。该装置还可以包括一个或多个进入端口或孔，其允许接近哺乳动物的末端的部分，以允许介入型医疗装置，治疗装置，外科手术支持设备或患者监视装置进入肢体的末端元件被布置。该装置还可以被配置为允许其他支撑部件，其可以包括IV或其它导管，这些部件可以访问位于温度调节装置内的末端的一部分。在一种配置中，当真空压力被施加到装置的内部区域时，该装置包括柔性材料，该柔性材料适于与设置在装置中的末端的表面一致。

2. 发明授权

US08182521B2 Methods and apparatus for increasing blood circulation 有权
标题翻译：增加血液循环的方法和装置
公开(公告)号：US08182521B2
公开(公告)日：2012-05-22
申请号：US11830486
申请日：2007-07-30
申请人： John Roy Kane , Scott A. Christensen , Nathan Hamilton , Stephen J. Williams
发明人： John Roy Kane , Scott A. Christensen , Nathan Hamilton , Stephen J. Williams
IPC分类号： A61F7/00 , A61H9/00
CPC分类号： A61F7/02 , A61F2007/0039 , A61F2007/0054 , A61H9/005 , A61H9/0057 , A61H9/0078 , A61H2201/0207 , A61H2201/0214 , A61H2201/0228 , A61H2201/0242 , A61H2201/025 , A61H2205/12 , A61H2209/00
摘要： A method and apparatus for the prevention of deep vein thrombosis (DVT), pulmonary embolism (PE), lower extremity edema, and other associated medical conditions by adjusting the temperature of the muscles of a foot or a leg, and/or applying vacuum or negative pressure to increase blood flow. A human extremity such as a leg is exposed to a negative pressure environment and/or a thermally controlled environment within a medical device. In one aspect, the device is portable. A thermal exchange unit and, optionally, a vacuum or negative pressure unit, are provided to increase blood flow and vasodilation. The device can be programmed by a controller in a manner to stimulate the muscles of the extremity to reduce pooling of blood therein.
摘要翻译：一种用于通过调节足部或腿部肌肉的温度和/或施加真空或用于预防深静脉血栓形成（DVT），肺栓塞（PE），下肢水肿以及其它相关的医疗状况的方法和装置负压增加血流量。诸如腿部的人类肢体暴露于医疗装置内的负压环境和/或热控环境中。在一个方面，该设备是便携式的。提供热交换单元和任选的真空或负压单元以增加血流和血管舒张。该装置可以由控制器以一种刺激肢体肌肉的方式进行编程，以减少血液中的血液聚集。

3. 发明授权

US08066752B2 Methods and apparatus for adjusting body core temperature 有权
标题翻译：调节身体核心温度的方法和装置
公开(公告)号：US08066752B2
公开(公告)日：2011-11-29
申请号：US11566575
申请日：2006-12-04
申请人： Nathan Hamilton , John Roy Kane , H. Lawson Fisher , Loren D. Titsworth , Barry Hickerson
发明人： Nathan Hamilton , John Roy Kane , H. Lawson Fisher , Loren D. Titsworth , Barry Hickerson
IPC分类号： A61F7/00
CPC分类号： A61F7/02 , A61F2007/0036 , A61F2007/0045 , A61G10/023
摘要： A method and apparatus for adjusting body core temperature are provided. The apparatus comprises an appendage chamber that is adapted to be disassembled from a heat exchange element. In one aspect, the appendage chamber is disposable. The appendage chamber provides a negative pressure environment for a patient's appendage placed therein. An appendage is heated and exposed to a negative pressure environment within the apparatus to efficiently raise or maintain the body core temperature of the patient.
摘要翻译：提供了一种用于调节体芯温度的方法和装置。该装置包括适于从热交换元件拆卸的附属室。一方面，附属室是一次性的。附属室为患者的附属物提供负压环境。附加物被加热并暴露于装置内的负压环境中以有效地提高或维持患者的身体核心温度。

4. 发明申请

US20110172749A1 METHODS AND APPARATUS FOR ENHANCING VASCULAR ACCESS IN AN APPENDAGE TO ENHANCE THERAPEUTIC AND INTERVENTIONAL PROCEDURES 有权
标题翻译：方法和装置，用于增强血管通路，增加治疗和传统程序
公开(公告)号：US20110172749A1
公开(公告)日：2011-07-14
申请号：US12987015
申请日：2011-01-07
申请人： Scott A. Christensen , John Roy Kane , Nathan Hamilton
发明人： Scott A. Christensen , John Roy Kane , Nathan Hamilton
IPC分类号： A61F7/00
CPC分类号： A61F7/02 , A61B2017/00084 , A61F2007/0034 , A61F2007/0035 , A61F2007/0036 , A61F2007/0043 , A61F2007/0045 , A61F2007/0054 , A61F2007/0095 , A61F2007/0239 , A61F2007/0273 , A61F2007/0274
摘要： Embodiments of the invention disclosed herein generally include methods and/or devices for increasing blood flow, controlling the vasodilatation of a patient's vascular structure, regulating the temperature of a portion of a mammal, and for improving various interventional procedures and/or therapeutic techniques. The device may also include one or more access ports, or apertures, that allow access to portions of the mammal's extremity to allow interventional type medical devices, therapeutic devices, surgical support equipment or patient monitoring devices to have access to the extremity on which a body element is disposed. The device may also be configured to allow other supporting components, which may include IV or other catheters, a means of accessing to a portion of the extremity positioned inside the temperature regulating device. In one configuration the device comprises flexible materials that are adapted to conform to the surface of the extremity disposed in the device when a vacuum pressure is applied to an internal region of the device.
摘要翻译：本文公开的本发明的实施方案通常包括用于增加血流量，控制患者血管结构的血管扩张，调节哺乳动物的一部分的温度以及改善各种介入手术和/或治疗技术的方法和/或装置。该装置还可以包括一个或多个进入端口或孔，其允许接近哺乳动物的末端的部分，以允许介入型医疗装置，治疗装置，外科手术支持设备或患者监视装置进入肢体的末端元件被布置。该装置还可以被配置为允许其他支撑部件，其可以包括IV或其它导管，以进入位于温度调节装置内部的末端的一部分的装置。在一种配置中，当真空压力被施加到装置的内部区域时，该装置包括柔性材料，该柔性材料适于与设置在装置中的末端的表面一致。

5. 发明授权

US09308148B2 Methods and apparatus for adjusting blood circulation 有权
标题翻译：调节血液循环的方法和装置
公开(公告)号：US09308148B2
公开(公告)日：2016-04-12
申请号：US11945999
申请日：2007-11-27
申请人： John Roy Kane , Scott A. Christensen , Nathan Hamilton , Stephen J. Williams
发明人： John Roy Kane , Scott A. Christensen , Nathan Hamilton , Stephen J. Williams
IPC分类号： A61H7/00
CPC分类号： A61H7/001 , A61H2201/0103 , A61H2201/0207 , A61H2201/0214 , A61H2201/0228 , A61H2201/0242 , A61H2201/025 , A61H2201/165 , A61H2201/5071 , A61H2205/065 , A61H2205/12 , A61H2230/50
摘要： A method and device for increasing blood flow by applying positive pressure to extremities of a mammal and/or controlling the temperature of the mammal. The device includes one or more collapsible and pliant body elements capable of expanding and flexibly applying pressurized compression forces to the extremity of the mammal by attaching one or more pressure-applying gas plenums as close to the extremity as possibly. The flexible extremity device can be used independently or can be used in conjunction with thermal pads disposed to the one or more collapsible and pliant body elements. Alternatively, the one or more collapsible and pliant body elements can be manufactured into thermal pads.
摘要翻译：一种通过向哺乳动物的四肢施加正压和/或控制哺乳动物的温度来增加血流量的方法和装置。该装置包括一个或多个可折叠和柔韧的身体元件，其能够通过将一个或多个压力施加气体增压室尽可能靠近地附接到末端而扩展并且将加压的压缩力施加到哺乳动物的末端。柔性末端装置可以独立使用，也可以与设置在一个或多个可折叠和柔韧的身体元件上的热垫结合使用。或者，可以将一个或多个可折叠和柔韧的主体元件制造成热垫。

6. 发明授权

US08603150B2 Methods and apparatus for adjusting blood circulation 有权
标题翻译：调节血液循环的方法和装置
公开(公告)号：US08603150B2
公开(公告)日：2013-12-10
申请号：US11870780
申请日：2007-10-11
申请人： John Roy Kane , Scott A. Christensen , Nathan Hamilton , Stephen J. Williams
发明人： John Roy Kane , Scott A. Christensen , Nathan Hamilton , Stephen J. Williams
IPC分类号： A61F7/00
CPC分类号： A61H9/0007 , A61F7/007 , A61F7/02 , A61F2007/0029 , A61F2007/0036 , A61F2007/0039 , A61F2007/0045 , A61F2007/0054 , A61F2007/0071 , A61F2007/0086 , A61H2201/0207 , A61H2201/0228 , A61H2201/10 , A61H2201/1635 , A61H2201/164 , A61H2205/065 , A61H2209/00 , B29C65/04 , B29K2995/0082 , B29L2031/753
摘要： Embodiments of the invention include a method and a device for increasing blood flow and controlling the temperature of a mammal by applying a desired pressure to extremities of a mammal. The device generally includes one or more collapsible and pliant body elements, capable of expanding from a first volume into an expanded second volume so the device can receive a portion of an extremity of the mammal therein and then be reduced from the expanded second volume into a pressurized third volume to conformably enclose the portion of the extremity. One or more thermal exchange units can be positioned in the one or more collapsible and pliant body elements. Accordingly, the temperature of the extremity of a mammal can be regulated by providing a heated or cooled fluid medium or electric thermal energy to the one or more thermal exchange units. Next, by evacuating the region in which the extremity is enclosed the contact surface area between the extremity of a mammal and the one or more thermal exchange units is increased, due to the external atmospheric pressure acting on the pliant body elements against the skin of the extremity of the mammal. The application of pressure assures that sufficient contact and thermal heat transfer (heating or cooling) is provided to the extremity of the mammal.
摘要翻译：本发明的实施方案包括通过向哺乳动物的四肢施加期望的压力来增加血流量并控制哺乳动物的温度的方法和装置。该装置通常包括一个或多个可折叠和柔韧的主体元件，其能够从第一容积膨胀成扩展的第二容积，使得装置可以接收哺乳动物的一部分末端，然后从膨胀的第二容积减小到加压第三体积以适形地包围末端的部分。一个或多个热交换单元可以定位在一个或多个可折叠和柔韧的身体元件中。因此，可以通过向一个或多个热交换单元提供加热或冷却的流体介质或电热能来调节哺乳动物末端的温度。接下来，通过抽出其中包围末端的区域，由于外部大气压力作用于柔韧的身体元件抵抗皮肤上的哺乳动物的末端与一个或多个热交换单元之间的接触表面积增加哺乳动物的极端。施加压力确保了向哺乳动物的末端提供足够的接触和热传递（加热或冷却）。

7. 发明申请

US20090177184A1 METHOD AND APPARATUS FOR IMPROVING VENOUS ACCESS 审中-公开
标题翻译：用于改善通风接入的方法和装置
公开(公告)号：US20090177184A1
公开(公告)日：2009-07-09
申请号：US12350920
申请日：2009-01-08
申请人： Scott A. Christensen , John Roy Kane , Nathan Hamilton
发明人： Scott A. Christensen , John Roy Kane , Nathan Hamilton
IPC分类号： A61F7/08 , A61H1/00 , A61M5/32
CPC分类号： A61H9/0057 , A61F7/007 , A61F2007/0034 , A61F2007/0036 , A61F2007/0045 , A61F2007/0054 , A61H9/0092 , A61H2201/0176 , A61H2201/02 , A61H2201/0228 , A61H2201/0242 , A61H2201/025 , A61H2201/5071 , A61H2201/5082 , A61H2230/25 , A61H2230/50
摘要： Embodiments of the invention include a method and a device for increasing vasodilatation and/or controlling the temperature of a mammal by applying a desired vacuum pressure to the skin of the extremity of a mammal. In some cases it is also desirable to provide heat to regions of the extremity of the mammal to further dilate the veins or arteries in the patient. In some cases it is also desirable to apply a contact pressure to regions of the extremity of the mammal to improve perfusion of these regions. In one embodiment, the device includes a device that is adapted to rigidly enclose a portion of an extremity of the mammal therein so that a sub-atmospheric pressure can be applied to the mammal's extremity, which is further discussed below.
摘要翻译：本发明的实施方案包括通过对哺乳动物末端的皮肤施加所需的真空压力来增加血管扩张和/或控制哺乳动物的温度的方法和装置。在一些情况下，还需要向哺乳动物末端的区域提供热量以进一步扩张患者体内的静脉或动脉。在一些情况下，还需要对哺乳动物末端的区域施加接触压力以改善这些区域的灌注。在一个实施例中，该装置包括适于将哺乳动物的末端的一部分刚性地包围的装置，使得能够对哺乳动物的末端施加次大气压，这在下面进一步讨论。

8. 发明申请

US20080132976A1 METHODS AND APPARATUS FOR ADJUSTING BLOOD CIRCULATION 有权
标题翻译：调节血液循环的方法和装置
公开(公告)号：US20080132976A1
公开(公告)日：2008-06-05
申请号：US11870780
申请日：2007-10-11
申请人： John Roy KANE , Scott A. Christensen , Nathan Hamilton , Stephen J. Williams
发明人： John Roy KANE , Scott A. Christensen , Nathan Hamilton , Stephen J. Williams
IPC分类号： A61B18/04
CPC分类号： A61H9/0007 , A61F7/007 , A61F7/02 , A61F2007/0029 , A61F2007/0036 , A61F2007/0039 , A61F2007/0045 , A61F2007/0054 , A61F2007/0071 , A61F2007/0086 , A61H2201/0207 , A61H2201/0228 , A61H2201/10 , A61H2201/1635 , A61H2201/164 , A61H2205/065 , A61H2209/00 , B29C65/04 , B29K2995/0082 , B29L2031/753
摘要： Embodiments of the invention include a method and a device for increasing blood flow and controlling the temperature of a mammal by applying a desired pressure to extremities of a mammal. The device generally includes one or more collapsible and pliant body elements, capable of expanding from a first volume into an expanded second volume so the device can receive a portion of an extremity of the mammal therein and then be reduced from the expanded second volume into a pressurized third volume to conformably enclose the portion of the extremity. One or more thermal exchange units can be positioned in the one or more collapsible and pliant body elements. Accordingly, the temperature of the extremity of a mammal can be regulated by providing a heated or cooled fluid medium or electric thermal energy to the one or more thermal exchange units. Next, by evacuating the region in which the extremity is enclosed the contact surface area between the extremity of a mammal and the one or more thermal exchange units is increased, due to the external atmospheric pressure acting on the pliant body elements against the skin of the extremity of the mammal. The application of pressure assures that sufficient contact and thermal heat transfer (heating or cooling) is provided to the extremity of the mammal.
摘要翻译：本发明的实施方案包括通过向哺乳动物的四肢施加期望的压力来增加血流量并控制哺乳动物的温度的方法和装置。该装置通常包括一个或多个可折叠和柔韧的主体元件，其能够从第一容积膨胀成扩展的第二容积，使得装置可以接收哺乳动物的一部分末端，然后从膨胀的第二容积减小到加压第三体积以适形地包围末端的部分。一个或多个热交换单元可以定位在一个或多个可折叠和柔韧的身体元件中。因此，可以通过向一个或多个热交换单元提供加热或冷却的流体介质或电热能来调节哺乳动物末端的温度。接下来，通过抽出其中包围末端的区域，由于外部大气压力作用于柔韧的身体元件抵抗皮肤上的哺乳动物的末端与一个或多个热交换单元之间的接触表面积增加哺乳动物的极端。施加压力确保了向哺乳动物的末端提供足够的接触和热传递（加热或冷却）。

9. 发明申请

US20080132816A1 Methods and Apparatus for Adjusting Blood Circulation 有权
标题翻译：调节血液循环的方法和装置
公开(公告)号：US20080132816A1
公开(公告)日：2008-06-05
申请号：US11945999
申请日：2007-11-27
申请人： John Roy Kane , Scott A. Christensen , Nathan Hamilton , Stephen J. Williams
发明人： John Roy Kane , Scott A. Christensen , Nathan Hamilton , Stephen J. Williams
IPC分类号： A61H7/00 , A61H1/00
CPC分类号： A61H7/001 , A61H2201/0103 , A61H2201/0207 , A61H2201/0214 , A61H2201/0228 , A61H2201/0242 , A61H2201/025 , A61H2201/165 , A61H2201/5071 , A61H2205/065 , A61H2205/12 , A61H2230/50
摘要： A method and device for increasing blood flow by applying positive pressure to extremities of a mammal and/or controlling the temperature of the mammal. The device includes one or more collapsible and pliant body elements capable of expanding and flexibly applying pressurized compression forces to the extremity of the mammal by attaching one or more pressure-applying gas plenums as close to the extremity as possibly. The flexible extremity device can be used independently or can be used in conjunction with thermal pads disposed to the one or more collapsible and pliant body elements. Alternatively, the one or more collapsible and pliant body elements can be manufactured into thermal pads.
摘要翻译：一种通过向哺乳动物的四肢施加正压和/或控制哺乳动物的温度来增加血流量的方法和装置。该装置包括一个或多个可折叠和柔韧的身体元件，其能够通过将一个或多个压力施加气体增压室尽可能靠近地附接到末端而扩展并且将加压的压缩力施加到哺乳动物的末端。柔性末端装置可以独立使用，也可以与设置在一个或多个可折叠和柔韧的身体元件上的热垫结合使用。或者，可以将一个或多个可折叠和柔韧的主体元件制造成热垫。

10. 发明授权

US07160316B2 Methods and apparatus for adjusting body core temperature 有权
标题翻译：调节身体核心温度的方法和装置
公开(公告)号：US07160316B2
公开(公告)日：2007-01-09
申请号：US10948121
申请日：2004-09-23
申请人： Nathan Hamilton , John Roy Kane , H. Lawson Fisher , Loren D. Titsworth , Barry Hickerson
发明人： Nathan Hamilton , John Roy Kane , H. Lawson Fisher , Loren D. Titsworth , Barry Hickerson
IPC分类号： A61F7/00
CPC分类号： A61F7/02 , A61F2007/0036 , A61F2007/0045 , A61G10/023
摘要： A method and apparatus for adjusting body core temperature are provided. The apparatus comprises an appendage chamber that is adapted to be disassembled from a heat exchange element. In one aspect, the appendage chamber is disposable. The appendage chamber provides a negative pressure environment for a patient's appendage placed therein. An appendage is heated and exposed to a negative pressure environment within the apparatus to efficiently raise or maintain the body core temperature of the patient.
摘要翻译：提供了一种用于调节体芯温度的方法和装置。该装置包括适于从热交换元件拆卸的附属室。一方面，附属室是一次性的。附属室为患者的附属物提供负压环境。附加物被加热并暴露于装置内的负压环境中以有效地提高或维持患者的身体核心温度。

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