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1. 发明授权

US08546581B2 Compounds, methods and formulations for the oral delivery of a glucagon-like peptide (Glp)-1 compound or a melanocortin-4 receptor (Mc4) agonist peptide 有权
标题翻译：用于口服递送胰高血糖素样肽（Glp）-1化合物或黑皮质素-4受体（Mc4）激动剂肽的化合物，方法和制剂
公开(公告)号：US08546581B2
公开(公告)日：2013-10-01
申请号：US13087255
申请日：2011-04-14
申请人： Louis Nickolaus Jungheim , John Mcneill McGill, III , Kenneth Jeff Thrasher , Robert Jason Herr , Muralikrishna Valluri
发明人： Louis Nickolaus Jungheim , John Mcneill McGill, III , Kenneth Jeff Thrasher , Robert Jason Herr , Muralikrishna Valluri
IPC分类号： C07D271/06 , C07D401/00 , C07D409/00
CPC分类号： C07D233/64 , A61K47/22 , C07D249/06 , C07D249/08 , C07D261/08 , C07D263/32 , C07D271/06 , C07D277/24 , C07D285/12 , C07D409/04 , C07D413/04
摘要： The present application relates to novel compounds, methods and formulations useful for the oral delivery of a glucagon like peptide-1 compound or a melanocortin 4 receptor agonist peptide.
摘要翻译：本申请涉及可用于胰高血糖素样肽-1化合物或黑皮质素4受体激动剂肽的口服递送的新化合物，方法和制剂。

2. 发明授权

US08274136B2 Semiconductor patch antenna 有权
标题翻译：半导体贴片天线
公开(公告)号：US08274136B2
公开(公告)日：2012-09-25
申请号：US12757506
申请日：2010-04-09
申请人： Sergey N. Makarov , Reinhold Ludwig , Francesca Scire-Scappuzzo , John McNeill
发明人： Sergey N. Makarov , Reinhold Ludwig , Francesca Scire-Scappuzzo , John McNeill
IPC分类号： H01L29/868 , H01L21/329 , H01L21/02
CPC分类号： H01Q1/2283 , H01Q9/0407
摘要： A semiconductor patch antenna for microwave radiation having a wide pin-junction or pn-junction with the depletion region or embodiments having a separating buried oxide (SiO2) layer between p- and n-doped regions as the natural resonator volume. Embodiments that do not include a metal ground plane and/or a metal patch are disclosed.
摘要翻译：一种用于微波辐射的半导体贴片天线，具有与耗尽区域较宽的pin-junction或pn结，或者具有在p和n掺杂区域之间的分离掩埋氧化物（SiO 2）层作为天然谐振器体积。公开了不包括金属接地平面和/或金属贴片的实施例。

3. 发明申请

US20110190205A1 Compounds, Methods and Formulations for the Oral Delivery of a Glucagon-Like Peptide (Glp)-1 Compound or a Melanocortin-4 Receptor (Mc4) Agonist Peptide 有权
标题翻译：口服胰岛素样肽（Glp）-1化合物或黑皮质素-4受体（Mc4）激动剂肽的口服递送的化合物，方法和制剂
公开(公告)号：US20110190205A1
公开(公告)日：2011-08-04
申请号：US13087255
申请日：2011-04-14
申请人： Louis Nickolaus JUNGHEIM , John McNeill MCGILL, III , Kenneth Jeff THRASHER , Robert Jason HERR , Muralikrishna VALLURI
发明人： Louis Nickolaus JUNGHEIM , John McNeill MCGILL, III , Kenneth Jeff THRASHER , Robert Jason HERR , Muralikrishna VALLURI
IPC分类号： A61K38/26 , C07D413/04 , A61K38/00 , A61K38/12 , A61P43/00
CPC分类号： C07D233/64 , A61K47/22 , C07D249/06 , C07D249/08 , C07D261/08 , C07D263/32 , C07D271/06 , C07D277/24 , C07D285/12 , C07D409/04 , C07D413/04
摘要： The present application relates to novel compounds, methods and formulations useful for the oral delivery of a glucagon like peptide-1 compound or a melanocortin 4 receptor agonist peptide.
摘要翻译：本申请涉及可用于胰高血糖素样肽-1化合物或黑皮质素4受体激动剂肽的口服递送的新化合物，方法和制剂。

4. 发明授权

US07947841B2 Compounds, methods and formulations for the oral delivery of a glucagon-like peptide (GLP)-1 compound or a melanocortin-4 receptor (MC4) agonist peptide 有权
标题翻译：胰高血糖素样肽（GLP）-1化合物或黑皮质素-4受体（MC4）激动剂肽的口服递送的化合物，方法和制剂
公开(公告)号：US07947841B2
公开(公告)日：2011-05-24
申请号：US12263722
申请日：2008-11-03
申请人： Louis Nickolaus Jungheim , John McNeill McGill, III , Kenneth Jeff Thrasher , Robert Jason Herr , Valluri Muralikrishna
发明人： Louis Nickolaus Jungheim , John McNeill McGill, III , Kenneth Jeff Thrasher , Robert Jason Herr , Valluri Muralikrishna
IPC分类号： C07D263/34 , C07D213/00 , C07D409/00
CPC分类号： C07D233/64 , A61K47/22 , C07D249/06 , C07D249/08 , C07D261/08 , C07D263/32 , C07D271/06 , C07D277/24 , C07D285/12 , C07D409/04 , C07D413/04
摘要： The present application relates to novel compounds, methods and formulations useful for the oral delivery of a glucagon like peptide-1 compound or a melanocortin 4 receptor agonist peptide.
摘要翻译：本申请涉及可用于胰高血糖素样肽-1化合物或黑皮质素4受体激动剂肽的口服递送的新化合物，方法和制剂。

5. 发明申请

US20090132458A1 Intelligent Drilling Advisor 有权
标题翻译：智能钻井顾问
公开(公告)号：US20090132458A1
公开(公告)日：2009-05-21
申请号：US12261198
申请日：2008-10-30
申请人： Michael L. Edwards , Cesar A. Gongora , Ganesh Tyer , David McGriffy , John McNeill , Donald F. Shafer , Chris Tolleson , David Wight
发明人： Michael L. Edwards , Cesar A. Gongora , Ganesh Tyer , David McGriffy , John McNeill , Donald F. Shafer , Chris Tolleson , David Wight
IPC分类号： G06N5/00 , E21B49/00
CPC分类号： E21B44/00 , G06N5/025
摘要： A method, apparatus, and program storage device for integrating and implementing rule-based, heuristic, wellbore key performance rate of penetration indicators advising drilling operations personnel based on the situational awareness of trended earth properties and real time wellbore sensor data, is disclosed.
摘要翻译：公开了一种用于整合并实施基于规则的，启发式的井眼关键性能比率的穿透指标的方法，装置和程序存储装置，其基于趋势地球属性和实时井眼传感器数据的情境意识向钻井作业人员提供建议。

6. 发明申请

US20060145899A1 Programmable error amplifier for sensing voltage error in the feedback path of digitially programmable voltage sources 有权
标题翻译：可编程误差放大器，用于感测数字可编程电压源的反馈路径中的电压误差
公开(公告)号：US20060145899A1
公开(公告)日：2006-07-06
申请号：US11029307
申请日：2005-01-05
申请人： Piotr Markowski , Chanchal Gupta , John McNeill
发明人： Piotr Markowski , Chanchal Gupta , John McNeill
IPC分类号： H03M7/00
CPC分类号： H02M3/1588 , H02M1/082 , H02M3/157 , Y02B70/1466
摘要： A programmable error amplifier (PEA) that may be used as part of a voltage regulation subsystem to control the output of a digitally programmable voltage source is disclosed. According to various embodiments, the PEA comprises an amplification circuit, an analog voltage sampling circuit and a digital reference voltage sampling circuit. The amplification circuit may employ a negative feedback configuration, and include an amplifier and a plurality of feedback capacitors. The analog voltage sampling circuit is responsive to an analog input voltage (such as the output of the programmable voltage source) and is coupled to the amplification circuit. During a first operational phase (the sampling phase), the analog voltage sampling circuit stores a charge dependent upon the analog input voltage, and during a second operational phase (the conversion phase), the analog voltage sampling circuit transfers the charge to the feedback capacitors of the amplification circuit. The digital reference voltage sampling circuit is responsive to a digital programming word and also is coupled to the amplification circuit. During the first (sampling) phase, the digital reference voltage sampling circuit stores a charge dependent upon the digital programming word, and during the second (conversion) phase transfers the charge to the feedback capacitors of the amplification circuit. A differential voltage based on the difference between the analog voltage and a reference voltage determined by the digital programming word appears across the input terminals of the amplifier.
摘要翻译：公开了可用作电压调节子系统的一部分以控制数字可编程电压源的输出的可编程误差放大器（PEA）。根据各种实施例，PEA包括放大电路，模拟电压采样电路和数字参考电压采样电路。放大电路可以采用负反馈配置，并且包括放大器和多个反馈电容器。模拟电压采样电路响应于模拟输入电压（例如可编程电压源的输出）并耦合到放大电路。在第一个操作阶段（采样阶段），模拟电压采样电路存储取决于模拟输入电压的电荷，在第二个操作阶段（转换阶段）期间，模拟电压采样电路将电荷转移到反馈电容器的放大电路。数字参考电压采样电路响应于数字编程字，并且还耦合到放大电路。在第一（采样）阶段期间，数字参考电压采样电路存储取决于数字编程字的电荷，并且在第二（转换）阶段期间，将电荷转移到放大电路的反馈电容器。基于模拟电压和由数字编程字确定的参考电压之间的差异的差分电压出现在放大器的输入端上。

7. 发明授权

US08492330B2 Formulation comprising GLP-1 有权
标题翻译：包含GLP-1的制剂
公开(公告)号：US08492330B2
公开(公告)日：2013-07-23
申请号：US13004964
申请日：2011-01-12
申请人： Mohammed Amin Khan , Bryan Edward Jones , John McNeill McGill
发明人： Mohammed Amin Khan , Bryan Edward Jones , John McNeill McGill
IPC分类号： A61K38/00
CPC分类号： A61K47/183 , A61K9/0095 , A61K9/08 , A61K38/26 , A61K47/18
摘要： The invention relates to formulations that demonstrate the feasibility of oral absorption comprising glucose-like peptide-1 compounds and specified delivery agents, and to methods of stimulating GLP-1 receptor in a subject in need of such stimulation, by administration of the formulation of the present invention.
摘要翻译：本发明涉及证明包含葡萄糖样肽-1化合物和特定递送剂的口服吸收的可行性的制剂以及在需要这种刺激的受试者中刺激GLP-1受体的方法，通过施用本发明。

8. 发明申请

US20130099184A1 POST HANDLING DEVICE 审中-公开
标题翻译：后处理设备
公开(公告)号：US20130099184A1
公开(公告)日：2013-04-25
申请号：US13701990
申请日：2011-06-09
申请人： Peter John McNeill
发明人： Peter John McNeill
IPC分类号： E04H17/26
CPC分类号： E04H17/265 , B66F15/00 , E04H17/263 , E21B19/00
摘要： A device for lifting a post out of the ground, including a part for engaging the post and an elongate body having a handle for applying a lever action to the part in order to lift the post from the ground, wherein the part is coupled to a stand and the stand is moveable relative to the body from a stowed condition to a deployed condition whereat the body is pivotally supported above the ground for rotation about the stand in order to effect the lever action.
摘要翻译：一种用于将立柱从地面上提起的装置，包括用于接合柱的部分和具有把手的细长主体，所述手柄用于向所述部件施加杠杆作用，以便将所述柱从地面抬起，其中所述部分与并且支架相对于身体从收起状态移动到展开状态，其中主体被枢转地支撑在地面上以在支架周围旋转以实现杠杆作用。

9. 发明授权

US07939494B2 Method for administering GLP-1 molecules 有权
标题翻译： GLP-1分子的施用方法
公开(公告)号：US07939494B2
公开(公告)日：2011-05-10
申请号：US12421590
申请日：2009-04-09
申请人： Mohammed Amin Khan , Bryan Edward Jones , John McNeill McGill
发明人： Mohammed Amin Khan , Bryan Edward Jones , John McNeill McGill
IPC分类号： A61K38/00
CPC分类号： A61K47/183 , A61K9/0095 , A61K9/08 , A61K38/26 , A61K47/18
摘要： The invention relates to formulations that demonstrate the feasibility of oral absorption comprising glucose-like peptide-1 compounds and specified delivery agents, and to methods of stimulating GLP-1 receptor in a subject in need of such stimulation, by administration of the formulation of the present invention.
摘要翻译：本发明涉及证明包含葡萄糖样肽-1化合物和特定递送剂的口服吸收的可行性的制剂以及在需要这种刺激的受试者中刺激GLP-1受体的方法，通过施用本发明。

10. 发明申请

US20100258919A1 SEMICONDUCTOR PATCH ANTENNA 有权
标题翻译：半导体天线
公开(公告)号：US20100258919A1
公开(公告)日：2010-10-14
申请号：US12757506
申请日：2010-04-09
申请人： Sergey N. Makarov , Reinhold Ludwig , Francesca Scire-Scappuzzo , John McNeill
发明人： Sergey N. Makarov , Reinhold Ludwig , Francesca Scire-Scappuzzo , John McNeill
IPC分类号： H01L29/868 , H01L21/329
CPC分类号： H01Q1/2283 , H01Q9/0407
摘要： A semiconductor patch antenna for microwave radiation having a wide pin-junction or pn-junction with the depletion region or embodiments having a separating buried oxide (SiO2) layer between p- and n-doped regions as the natural resonator volume. Embodiments that do not include a metal ground plane and/or a metal patch are disclosed.
摘要翻译：一种用于微波辐射的半导体贴片天线，具有与耗尽区域较宽的pin-junction或pn结，或者具有在p和n掺杂区域之间的分离掩埋氧化物（SiO 2）层作为天然谐振器体积。公开了不包括金属接地平面和/或金属贴片的实施例。

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