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1. 发明申请

US20160032047A1 Peg-based adhesive phenylic derivatives and methods of synthesis and use 审中-公开
标题翻译：聚酯类粘合剂苯基衍生物及其合成与使用方法
公开(公告)号：US20160032047A1
公开(公告)日：2016-02-04
申请号：US14776187
申请日：2014-03-14
申请人： John L. MURPHY , Jeffrey L. DALSIN , Arinne N. LYMAN , Christopher P. RADANO , DSM IP ASSETS B.V.
发明人： John L MURPHY , Jeffrey L DALSIN , Arinne N LYMAN , Christopher P RADANO
IPC分类号： C08G65/48 , C08L71/02 , A61L27/18 , C09D5/16 , A61L24/04
CPC分类号： C08G65/48 , A61L24/0031 , A61L24/046 , A61L27/18 , A61L27/34 , A61L27/52 , A61L2420/06 , A61L2420/08 , C08G65/3317 , C08G65/3326 , C08G65/33313 , C08G65/33396 , C08G65/334 , C08G65/3344 , C08G2650/50 , C08L71/02 , C09D5/1637 , C09J171/02
摘要： The invention provides compositions that use phenylic derivatives to provide adhesive properties. Selection of phenylic derivatives with linkers or linking groups, and the linkages between the linkers or linking groups with polyalkylene oxides, provided herein may be configured to control curing time, biodegradation and/or swelling.
摘要翻译：本发明提供使用苯基衍生物提供粘合性质的组合物。选择具有接头或连接基团的苯基衍生物以及本文提供的接头或连接基团与聚环氧烷的连接可以被配置为控制固化时间，生物降解和/或溶胀。

2. 发明授权

US08383092B2 Bioadhesive constructs 有权
标题翻译：生物粘附构造
公开(公告)号：US08383092B2
公开(公告)日：2013-02-26
申请号：US12568527
申请日：2009-09-28
申请人： Bruce P. Lee , Laura Vollenweider , John L. Murphy , Fangmin Xu , Jeffrey L. Dalsin , Jeanne Virosco , William Lew , Jed White
发明人： Bruce P. Lee , Laura Vollenweider , John L. Murphy , Fangmin Xu , Jeffrey L. Dalsin , Jeanne Virosco , William Lew , Jed White
IPC分类号： A61K31/74
CPC分类号： A61L24/001 , A61B17/00491 , A61B17/0057 , A61B17/1146 , A61B2017/0061 , A61L24/043 , A61L31/041 , A61L31/14 , C08G65/3322 , C08G65/33306 , C08G65/33313 , C08G2650/50 , C08L2203/02 , C09J171/02
摘要： The invention describes substrates, such as prosthetics, films, nonwovens, meshes, etc. that are treated with a bioadhesive. The bioadhesive includes polymeric substances that have phenyl moieties with at least two hydroxyl groups. The bioadhesive constructs can be used to treat and repair, for example, hernias and damaged tendons.
摘要翻译：本发明描述了用生物粘合剂处理的基材，例如假体，薄膜，无纺布，网眼等。生物粘附剂包括具有至少两个羟基的苯基部分的聚合物质。生物粘附结构可用于治疗和修复例如疝气和损伤的腱。

3. 发明申请

US20120116424A1 ADHESIVE COMPOUNDS AND METHODS USE FOR HERNIA REPAIR 有权
标题翻译：粘合剂和方法用于HERNIA修复
公开(公告)号：US20120116424A1
公开(公告)日：2012-05-10
申请号：US13292527
申请日：2011-11-09
申请人： Bruce P. Lee , Jeffrey L. Dalsin , John L. Murphy , Laura Vollenweider , Arinne N. Lyman , Fangmin Xu , Jediah White , William D. Lew , Michael Brodie
发明人： Bruce P. Lee , Jeffrey L. Dalsin , John L. Murphy , Laura Vollenweider , Arinne N. Lyman , Fangmin Xu , Jediah White , William D. Lew , Michael Brodie
IPC分类号： A61B17/03
CPC分类号： A61L24/001 , A61F2/0063 , A61L24/0005 , A61L24/043 , A61L24/046 , A61L24/06 , C09J171/02 , C08L71/02 , C08L67/04
摘要： The invention describes new synthetic medical adhesives and films which exploit the key components of natural marine mussel adhesive proteins.
摘要翻译：本发明描述了利用天然海洋贻贝粘合蛋白的关键组分的新的合成医用胶粘剂和薄膜。

4. 发明授权

US07743915B2 Carton having adjustment indicia 有权
标题翻译：纸箱有调整标记
公开(公告)号：US07743915B2
公开(公告)日：2010-06-29
申请号：US11469628
申请日：2006-09-01
申请人： John L. Murphy
发明人： John L. Murphy
IPC分类号： A24F15/00
CPC分类号： B65D85/1045 , B31B50/003 , B31B50/006 , B31B2100/00 , B31B2120/30 , B65D2203/00 , B65D2203/12
摘要： Cartons are disclosed for packaging articles, wherein the cartons have indicia printed thereon to facilitate adjustment of the dimensions of the blanks used to form the cartons, or of the forming machinery on which such cartons may be erected.
摘要翻译：公开了用于包装物品的纸箱，其中纸箱上印有标记以便于调整用于形成纸箱的坯料的尺寸，或者可以在其上竖立有这种纸箱的成形机械。

5. 发明申请

US20100137903A1 BIOADHESIVE CONSTRUCTS 审中-公开
标题翻译：生物建筑
公开(公告)号：US20100137903A1
公开(公告)日：2010-06-03
申请号：US12568529
申请日：2009-09-28
申请人： Bruce P. Lee , Laura Vollenweider , John L. Murphy , Fangmin Xu , Jeffrey L. Dalsin , Jeanne Virosco , William Lew , Jed White
发明人： Bruce P. Lee , Laura Vollenweider , John L. Murphy , Fangmin Xu , Jeffrey L. Dalsin , Jeanne Virosco , William Lew , Jed White
IPC分类号： A61B17/03 , A61L24/00
CPC分类号： A61K31/765
摘要： The invention describes substrates, such as prosthetics, films, nonwovens, meshes, etc. that are treated with a bioadhesive. The bioadhesive includes polymeric substances that have phenyl moieties with at least two hydroxyl groups. The bioadhesive constructs can be used to treat and repair, for example, hernias and damaged tendons.
摘要翻译：本发明描述了用生物粘合剂处理的基材，例如假体，薄膜，无纺布，网眼等。生物粘附剂包括具有至少两个羟基的苯基部分的聚合物质。生物粘附结构可用于治疗和修复例如疝气和损伤的腱。

6. 发明申请

US20070170081A1 CARTON HAVING ADJUSTMENT INDICIA 有权
标题翻译：有调整指数的纸箱
公开(公告)号：US20070170081A1
公开(公告)日：2007-07-26
申请号：US11469628
申请日：2006-09-01
申请人： John L. Murphy
发明人： John L. Murphy
IPC分类号： B65D85/00
CPC分类号： B65D85/1045 , B31B50/003 , B31B50/006 , B31B2100/00 , B31B2120/30 , B65D2203/00 , B65D2203/12
摘要： Cartons are disclosed for packaging articles, wherein the cartons have indicia printed thereon to facilitate adjustment of the dimensions of the blanks used to form the cartons, or of the forming machinery on which such cartons may be erected.
摘要翻译：公开了用于包装物品的纸箱，其中纸箱上印有标记以便于调整用于形成纸箱的坯料的尺寸，或者可以在其上竖立有这种纸箱的成形机械。

7. 发明授权

US06623640B2 Phase separator having multiple separation units, upflow reactor apparatus, and methods for phase separation 失效
公开(公告)号：US06623640B2
公开(公告)日：2003-09-23
申请号：US09906956
申请日：2001-07-16
申请人： Jelte Lanting , John L. Murphy, III
发明人： Jelte Lanting , John L. Murphy, III
IPC分类号： C02F300
CPC分类号： B01D21/2494 , B01D3/009 , B01D3/20 , B01D19/0015 , B01J8/0065 , B01J8/22 , C02F1/5281 , C02F3/2846 , C12M21/04 , C12M23/36 , C12M27/20
摘要： A phase separator, upflow reactor apparatuses and methods for separating phases are provided. The phase separator includes a first separation unit and a second separation unit, each of which has walls defining a coagulation area. One of the walls adjoins a deflector inclined to the horizontal and vertical. The separator also includes a plurality of parallel plates spaced from each other and vertically and horizontally inclined which each have a lower edge. The other wall of the separator adjoins one of the parallel plates and the deflector extends below and across the lower edges of the parallel plates. Each of the first and the second separation units is capable of separating a gas from a liquid by diverting the gas around one wall of each of the separation units and by creating a circulation of the liquid around at least one of the parallel plates such that liquid is directed into the coagulation area. The upflow reactor apparatus includes phase separators having multiple units alone or in combination with a further separator in series arrangements. The methods include providing an upflow of gas and liquid within an upflow reactor apparatus having phase separators as noted herein, providing a liquid circulation around at least one of the parallel plates of the separator by diverting gas flow to one or more gas collecting areas such that the liquid circulation provides a downwardly directed flow around the parallel plates and liquid is directed to one or more coagulation areas. Gas from the gas collecting area or areas is directed from the upflow reactor apparatus through a gas outlet.

8. 发明授权

US06309553B1 Phase separator having multiple separation units, upflow reactor apparatus, and methods for phase separation 有权
标题翻译：具有多个分离单元的相分离器，上流式反应器装置和相分离方法
公开(公告)号：US06309553B1
公开(公告)日：2001-10-30
申请号：US09406976
申请日：1999-09-28
申请人： Jelte Lanting , John L. Murphy, III
发明人： Jelte Lanting , John L. Murphy, III
IPC分类号： C02F100
CPC分类号： B01D21/2494 , B01D3/009 , B01D3/20 , B01D19/0015 , B01J8/0065 , B01J8/22 , C02F1/5281 , C02F3/2846 , C12M21/04 , C12M23/36 , C12M27/20
摘要： A phase separator, upflow reactor apparatuses and methods for separating phases are provided. The phase separator includes a first separation unit and a second separation unit, each of which has walls defining a coagulation area. One of the walls adjoins a deflector inclined to the horizontal and vertical. The separator also includes a plurality of parallel plates spaced from each other and vertically and horizontally inclined which each have a lower edge. The other wall of the separator adjoins one of the parallel plates and the deflector extends below and across the lower edges of the parallel plates. Each of the first and the second separation units is capable of separating a gas from a liquid by diverting the gas around one wall of each of the separation units and by creating a circulation of the liquid around at least one of the parallel plates such that liquid is directed into the coagulation area. The upflow reactor apparatus includes phase separators having multiple units alone or in combination with a further separator in series arrangements. The methods include providing an upflow of gas and liquid within an upflow reactor apparatus having phase separators as noted herein, providing a liquid circulation around at least one of the parallel plates of the separator by diverting gas flow to one or more gas collecting areas such that the liquid circulation provides a downwardly directed flow around the parallel plates and liquid is directed to one or more coagulation areas. Gas from the gas collecting area or areas is directed from the upflow reactor apparatus through a gas outlet.
摘要翻译：提供了一种相分离器，上流式反应器装置和分离相的方法。相分离器包括第一分离单元和第二分离单元，每个单元具有限定凝结区域的壁。其中一个墙壁与倾斜水平相垂直。分离器还包括彼此间隔开并且垂直和水平倾斜的多个平行板，它们各自具有下边缘。分离器的另一个壁与平行板之一相邻并且偏转器延伸到平行板的下边缘并横过平行板的下边缘。第一分离单元和第二分离单元中的每一个能够通过将气体绕着每个分离单元的一个壁分开来分离气体，并且通过在至少一个平行板周围产生液体的循环，使得液体被引导到凝血区域。上流式反应器装置包括单独的多个单元或与串联装置中的另一分离器组合的相分离器。所述方法包括在具有如本文所述的相分离器的上流式反应器设备中提供气体和液体的上流，通过将气流转向一个或多个气体收集区域来提供围绕隔板的至少一个平行板的液体循环，使得液体循环在平行板周围提供向下的流动，液体被引导到一个或多个凝结区域。来自气体收集区域或区域的气体通过气体出口从上流反应器装置引导。

9. 发明申请

US20120016390A1 BIOADHESIVE COMPOUNDS AND METHODS OF SYNTHESIS AND USE 审中-公开
标题翻译：生物化合物及其合成和使用方法
公开(公告)号：US20120016390A1
公开(公告)日：2012-01-19
申请号：US13184234
申请日：2011-07-15
申请人： Bruce P. Lee , John L. Murphy , Laura Vollenweider , Jeffrey L. Dalsin , Arinne N. Lyman
发明人： Bruce P. Lee , John L. Murphy , Laura Vollenweider , Jeffrey L. Dalsin , Arinne N. Lyman
IPC分类号： A61B17/03 , C08G63/08 , C08L67/04 , C08G63/06
CPC分类号： C08G63/08 , A61L31/10 , C08G63/664 , C08G69/40 , C08G69/44 , C09J167/04 , C09J177/12
摘要： The invention describes new synthetic medical adhesives and antifouling coatings which exploit the key components of natural marine mussel adhesive proteins.
摘要翻译：本发明描述了利用天然海洋贻贝粘合蛋白的关键组分的新的合成医用胶粘剂和防污涂料。

10. 发明申请

US20120003888A1 BIOADHESIVE CONSTRUCTS WITH POLYMER BLENDS 审中-公开
标题翻译：具有聚合物混合物的生物结构
公开(公告)号：US20120003888A1
公开(公告)日：2012-01-05
申请号：US13148283
申请日：2010-02-05
申请人： Bruce P. Lee , Jeffrey L. Dalsin , Laura Vollenweider , John L. Murphy , Fangmin Xu
发明人： Bruce P. Lee , Jeffrey L. Dalsin , Laura Vollenweider , John L. Murphy , Fangmin Xu
IPC分类号： C09J7/04 , C09J7/02 , C08L77/00
CPC分类号： A61L24/043 , C08G65/3317 , C08G65/33396 , C08G71/04 , C09D5/1637 , C09J175/04 , Y10T428/2852 , Y10T442/10 , Y10T442/2738
摘要： The invention describes substrates, such as prosthetics, films, nonwovens, meshes, etc. that are treated with a bioadhesive polymer blend. The bioadhesive includes polymeric substances that have phenyl moieties with at least two hydroxyl groups. The bioadhesive blend constructs can be used to treat and repair, for example, hernias and damaged tendons.
摘要翻译：本发明描述了用生物粘附聚合物共混物处理的基材，例如假体，薄膜，无纺布，网眼等。生物粘附剂包括具有至少两个羟基的苯基部分的聚合物质。生物粘附混合物构建体可用于治疗和修复例如疝气和损伤的腱。

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