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1. 发明授权

US08881894B2 Multiple-compartment applicator 有权
标题翻译：多室涂抹器
公开(公告)号：US08881894B2
公开(公告)日：2014-11-11
申请号：US12195788
申请日：2008-08-21
申请人： John C. Castel , R. Patrick Abergel
发明人： John C. Castel , R. Patrick Abergel
IPC分类号： B65D25/08 , B65D1/09 , A61K9/70 , A61K31/375
CPC分类号： A61K9/7023 , A61K31/375
摘要： A multiple-compartment ascorbic acid delivery unit is provided. The first compartment is impermeable to oxygen and ultraviolet light and contains a solid vitamin-containing composition comprising ascorbic acid or its pharmaceutically acceptable salts and esters. The second compartment is liquid impermeable and contains a pharmaceutically acceptable carrier system. The first compartment is entirely enclosed within said second compartment or vice versa. An opening is formed in the inner compartment in order to combine the contents of the two compartments to form an ascorbic acid carrier composition prior to delivery to the patient.
摘要翻译：提供多室抗坏血酸输送单元。第一隔室不透氧和紫外线，并且含有含有抗坏血酸或其药学上可接受的盐和酯的含固体含维生素的组合物。第二隔室是液体不可渗透的并且含有药学上可接受的载体体系。第一隔间完全封闭在所述第二隔间内，反之亦然。在内隔室中形成开口，以便在输送到患者之前组合两个隔间的内容物以形成抗坏血酸载体组合物。

2. 发明申请

US20100047326A1 Multiple-Compartment Applicator 有权
标题翻译：多室施放器
公开(公告)号：US20100047326A1
公开(公告)日：2010-02-25
申请号：US12195788
申请日：2008-08-21
申请人： John C. Castel , R. Patrick Abergel
发明人： John C. Castel , R. Patrick Abergel
IPC分类号： A61K9/70 , A61K31/375 , A61P43/00
CPC分类号： A61K9/7023 , A61K31/375
摘要： A multiple-compartment ascorbic acid delivery unit is provided. The first compartment is impermeable to oxygen and ultraviolet light and contains a solid vitamin-containing composition comprising ascorbic acid or its pharmaceutically acceptable salts and esters. The second compartment is liquid impermeable and contains a pharmaceutically acceptable carrier system. The first compartment is entirely enclosed within said second compartment or vice versa. An opening is formed in the inner compartment in order to combine the contents of the two compartments to form an ascorbic acid carrier composition prior to delivery to the patient.
摘要翻译：提供多室抗坏血酸输送单元。第一隔室不透氧和紫外线，并且含有含有抗坏血酸或其药学上可接受的盐和酯的含固体含维生素的组合物。第二隔室是液体不可渗透的并且含有药学上可接受的载体体系。第一隔间完全封闭在所述第二隔间内，反之亦然。在内隔室中形成开口，以便在输送到患者之前组合两个隔间的内容物以形成抗坏血酸载体组合物。

3. 发明授权

US6068606A Back support belt 失效
标题翻译：背部支撑带
公开(公告)号：US6068606A
公开(公告)日：2000-05-30
申请号：US101668
申请日：1993-08-03
申请人： John C. Castel , Dawn S. Castel , Michael R. Hall
发明人： John C. Castel , Dawn S. Castel , Michael R. Hall
IPC分类号： A61F5/02 , A61F5/00
CPC分类号： A61F5/028 , A41D13/0525
摘要： A back support brace for supporting the back of a wearer of the brace for preventing injuries and reinforcing proper lifting mechanics during lifting activities comprises a back panel, a left side panel and a right side panel wherein the left and right side panels are secured at opposite ends of the back panel and are wrappable around the waist of a wearer and adjustably securable thereto. Aligned pairs of belt loops are provided on an inner surface of the brace and are adapted to receive a belt for holding up the pants of the wearer of the brace therethrough so as to prevent the brace from being advanced out of a preset position during lifting activities. A lower edge of the brace includes cutout portions generally positioned above the thighs of the wearer such that the lower edge is contoured to conform to the shape of the wearer throughout lifting activities. Elastic insets extend over the cutout portions to increase tension across the back panel.
摘要翻译：用于支撑用于防止伤害并且在提升活动期间加强适当提升机构的支撑件的背部的后支撑支架包括后板，左侧板和右侧板，其中左侧板和右侧板固定在相对的位置背面板的端部并且可围绕佩戴者的腰部包装并可调整地固定在其上。对齐的皮带环设置在支架的内表面上，并且适于容纳用于将支架穿用者的裤子夹持的带，以防止支架在提升活动期间被推出预设位置。支架的下边缘包括通常位于穿着者的大腿上方的切口部分，使得下部边缘的轮廓在整个提升活动期间符合穿戴者的形状。弹性插件延伸穿过切口部分以增加横跨后面板的张力。

4. 发明授权

US4535777A Method of providing electrical stimulation of tissue 失效
标题翻译：提供电刺激组织的方法
公开(公告)号：US4535777A
公开(公告)日：1985-08-20
申请号：US656403
申请日：1984-09-28
申请人： John C. Castel
发明人： John C. Castel
IPC分类号： A61N1/34 , A61N1/36
CPC分类号： A61N1/36021 , A61N1/36003
摘要： An electrotherapeutic method of providing electrical stimulation to human or animal tissue. A stimulating pulse train, having a primary frequency of 500 Hz to 100,000 Hz, is coupled to two electrodes attached to the portion of tissue to be stimulated. The train of pulses of the primary frequency are gated on and off so that they are applied and discontinued in predetermined intervals. For neural stimulation, the gating is performed at 0.1 Hz to 200 Hz. For muscle stimulation, the current is provided for predetermined intervals of 0.001 to 100 seconds and is discontinued in alternate intervals for 0.001 to 100 seconds. The stimulating pulse train may be amplitude modulated so that its amplitude rises at the beginning of each on-time period and falls at the end of each on-time period, the rise and fall time varying between 0.5% and 50% of the total on-time of the stimulating current.
摘要翻译：向人或动物组织提供电刺激的电疗方法。具有500Hz至100,000Hz的主频率的刺激脉冲串耦合到附接到待刺激的组织部分的两个电极。初级频率的脉冲序列被选通和关闭，使得它们以预定的间隔被施加和停止。对于神经刺激，门控以0.1Hz至200Hz进行。对于肌肉刺激，电流以0.001至100秒的预定间隔提供，并且以交替的间隔停止0.001至100秒。刺激脉冲序列可以进行幅度调制，使其幅度在每个接通时间段的开始时上升，并且在每个接通时间段结束时下降，上升和下降时间在总和的0.5％至50％之间变化 - 刺激电流的时间。

5. 发明授权

US5413550A Ultrasound therapy system with automatic dose control 失效
标题翻译：具有自动剂量控制的超声治疗系统
公开(公告)号：US5413550A
公开(公告)日：1995-05-09
申请号：US95102
申请日：1993-07-21
申请人： John C. Castel
发明人： John C. Castel
IPC分类号： A61H23/02 , A61N7/00 , A61H1/00
CPC分类号： A61N7/00 , A61H23/0245 , A61H2201/5007
摘要： An ultrasound therapy system with automatic dose control includes an ultrasound transducer, an ultrasound generator controllable in frequency and power output connected to the transducer, a system controller interfaced to the generator, input switches interfaced to the controller to enable the input of selected ultrasound treatment parameters, and a display interfaced to the controller. The controller is programmed to calculate an ultrasound treatment dosage in terms of frequency, ultrasound intensity, and treatment time from the entered treatment parameters. Once treatment is started, the controller tracks the accumulated dosage applied to the tissue. The clinician can vary the intensity or treatment time, and the controller will recalculate the other factor for the remaining portion of the unapplied treatment dosage.
摘要翻译：具有自动剂量控制的超声治疗系统包括超声换能器，可连接到换能器的频率和功率输出可控的超声波发生器，与发生器相连的系统控制器，与控制器接口的输入开关，以使输入选定的超声治疗参数以及与控制器接口的显示器。控制器被编程为根据输入的治疗参数计算超声治疗剂量的频率，超声强度和治疗时间。一旦开始治疗，控制器跟踪施加到组织上的累积剂量。临床医生可以改变强度或治疗时间，并且控制器将重新计算未应用治疗剂量的剩余部分的另一个因素。

6. 发明授权

US08491212B2 Multi-functional applicator 有权
标题翻译：多功能涂抹器
公开(公告)号：US08491212B2
公开(公告)日：2013-07-23
申请号：US12049800
申请日：2008-03-17
申请人： John C. Castel , R. Patrick Abergel
发明人： John C. Castel , R. Patrick Abergel
IPC分类号： B43K5/14
CPC分类号： A61M35/006 , A45D34/04 , A45D2034/007 , A45D2040/0093 , A45D2200/058 , A45D2200/1018 , A45D2200/1045 , A45D2200/1054 , A61F13/38
摘要： A multifunctional multi-compartment applicator for the stable storage of solid ascorbic acid and topical application of ascorbic acid in solution to the skin, the applicator having an absorbent end and an abrasive end.
摘要翻译：一种用于稳定储存固体抗坏血酸并在溶液中局部施用抗坏血酸至皮肤的多功能多室施用器，该涂抹器具有吸收端和研磨端。

7. 发明授权

US5086788A Hand-held physiological stimulation applicator 失效
标题翻译：手持式生理刺激器
公开(公告)号：US5086788A
公开(公告)日：1992-02-11
申请号：US206440
申请日：1988-06-13
申请人： John C. Castel , Alexander Bally
发明人： John C. Castel , Alexander Bally
IPC分类号： A61H23/02 , A61N1/36
CPC分类号： A61N1/36014 , A61H23/0245 , A61H2201/10
摘要： A hand-held physiological stimulation and treatment signal applicator. The applicator includes a housing having a portion in which electrical controls are mounted for facilitated manipulation thereof by the user's hand embracing the housing portion in the use of the apparatus. Different types of physiological treatment signals may be provided separately or in combination from the associated power sources and controlled by the housing mounted controls. The applicator head provided for facial engagement with the patient's tissue is swivelly mounted to the end of the applicator housing for facilitated adjustment of the head to insure desired facial engagement between the head and patient's tissue. Structure is provided for providing positive grasping of the applicator housing adjacent the applicator head while preventing interference between the user's fingers and the patient's tissue adjacent the head.
摘要翻译：手持生理刺激和治疗信号施加器。施用器包括壳体，其具有安装电控制器的部分，以便在使用该装置时使用者的手包围壳体部分便于其操纵。不同类型的生理治疗信号可以单独地或与相关联的电源组合提供并且由外壳安装的控制器控制。设置用于与患者组织面部接合的施用器头可旋转地安装到施用器壳体的端部，以便于头部的调节，以确保头部和患者组织之间期望的面部接合。提供结构用于提供邻近施用器头的施用器壳体的正向抓握，同时防止使用者的手指与邻近头部的患者组织之间的干扰。

8. 外观设计

USD315958S Physiological stimulator 失效
公开(公告)号：USD315958S
公开(公告)日：1991-04-02
申请号：US207055
申请日：1988-06-13
申请人： John C. Castel , Alexander Bally
设计人： John C. Castel , Alexander Bally

9. 发明授权

US4453547A T-Wave inhibiting system 失效
标题翻译： T波抑制系统
公开(公告)号：US4453547A
公开(公告)日：1984-06-12
申请号：US251139
申请日：1981-04-06
申请人： John C. Castel , Richard G. Kerwin
发明人： John C. Castel , Richard G. Kerwin
IPC分类号： A61N1/08 , A61N1/36
CPC分类号： A61N1/08 , Y10S128/908
摘要： An electrical inhibitor system is disclosed for suppressing the application of transcutaneous nerve stimulator (TNS) signals during the T-wave portion of a heartbeat. The system includes a sensing circuit which is coupled to detect the R-S waveform produced by the heart during its normal beating pattern. Upon detection of the R-S portion of the waveform, an electrical signal is produced and coupled to timing circuitry to produce a timing signal having a duration in excess of the normal period of the T-wave portion of the heartbeat. The timing signal is to inhibit the output of a transcutaneous nerve stimulator during the T-wave portion of the heartbeat. When the inhibiting circuit and transcutaneous nerve stimulator are coupled to a patient, the system provides an inhibiting signal beginning during the R-S portion of the waveform and extending through the T-wave portion of the hearbeat to prevent application of the output from the transcutaneous nerve stimulator during the vulnerable period of the heart. The transcutaneous nerve stimulator can thus be used without endangering the patient from electrical stimulation.
摘要翻译：公开了用于抑制在心跳的T波部分期间经皮神经刺激器（TNS）信号的应用的电抑制剂系统。该系统包括感测电路，该感测电路被耦合以在其正常的跳动模式期间检测由心脏产生的R-S波形。在检测到波形的R-S部分时，产生电信号并耦合到定时电路以产生具有超过心跳的T波部分的正常周期的持续时间的定时信号。定时信号是在心跳的T波部分期间抑制经皮神经刺激器的输出。当抑制电路和经皮神经刺激器耦合到患者时，该系统在波形的RS部分期间提供禁止信号，并且延伸穿过听觉器的T波部分，以防止经皮神经刺激器的输出在心脏的脆弱时期。因此，可以使用经皮神经刺激器，而不危及患者的电刺激。

10. 发明申请

US20090232580A1 Multi-Functional Applicator 有权
标题翻译：多功能敷贴机
公开(公告)号：US20090232580A1
公开(公告)日：2009-09-17
申请号：US12049800
申请日：2008-03-17
申请人： John C. Castel , R. Patrick Abergel
发明人： John C. Castel , R. Patrick Abergel
IPC分类号： B05C11/00 , A61K8/02 , A45D40/26 , B43K5/02
CPC分类号： A61M35/006 , A45D34/04 , A45D2034/007 , A45D2040/0093 , A45D2200/058 , A45D2200/1018 , A45D2200/1045 , A45D2200/1054 , A61F13/38
摘要： A multifunctional multi-compartment applicator for the stable storage of solid ascorbic acid and topical application of ascorbic acid in solution to the skin, the applicator having an absorbent end and an abrasive end.
摘要翻译：一种用于稳定储存固体抗坏血酸并在溶液中局部施用抗坏血酸至皮肤的多功能多室施用器，该涂抹器具有吸收端和研磨端。

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