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1. 发明授权

US08961403B2 Compact fluorescence endoscopy video system 有权
标题翻译：紧凑型荧光内窥镜视频系统
公开(公告)号：US08961403B2
公开(公告)日：2015-02-24
申请号：US12761462
申请日：2010-04-16
申请人： Richard W. Cline , John J. P. Fengler , Joachim W. Boehm
发明人： Richard W. Cline , John J. P. Fengler , Joachim W. Boehm
IPC分类号： A61B1/04 , A61B1/06 , A61B5/00 , A61B1/045 , A61B1/05 , A61B1/267 , A61B1/00
CPC分类号： A61B5/0071 , A61B1/00009 , A61B1/00057 , A61B1/00186 , A61B1/041 , A61B1/043 , A61B1/045 , A61B1/051 , A61B1/06 , A61B1/063 , A61B1/0638 , A61B1/0646 , A61B1/0669 , A61B1/2676 , A61B5/0084 , G01N21/6458 , G06F19/00
摘要： A fluorescence endoscopy video system includes a multimode light source that produces light for color and fluorescence imaging modes. Light from the light source is transmitted through an endoscope to the tissue under observation. The system also includes a compact camera for color and fluorescence imaging. Images obtained through the endoscope are optically divided and projected onto one or more image sensors by a fixed beam splitter in the camera. The fixed beam splitter eliminates the need for inserting a movable mirror into the light path between the endoscope and the image sensors. Image signals from the camera are processed in the system processor/controller where a contrast enhancement function can be applied. The contrast enhancement function increases the color contrast between normal tissue and tissue suspicious for early cancer. Finally, the system also includes a calibration feature whereby the system performance can be maintained when used with different endoscopes.
摘要翻译：荧光内窥镜视频系统包括产生用于彩色和荧光成像模式的光的多模光源。来自光源的光通过内窥镜透射到观察的组织。该系统还包括一个用于彩色和荧光成像的小型相机。通过内窥镜获得的图像通过照相机中的固定分束器被光学分割并投影到一个或多个图像传感器上。固定分束器不需要将可移动反射镜插入到内窥镜和图像传感器之间的光路中。来自相机的图像信号在可应用对比度增强功能的系统处理器/控制器中进行处理。对比度增强功能增加了早期癌症可疑的正常组织和组织之间的颜色对比。最后，该系统还包括校准特征，从而当与不同的内窥镜一起使用时可以维持系统性能。

2. 发明申请

US20080228037A1 COMPACT FLUORESCENCE ENDOSCOPY VIDEO SYSTEM 有权
标题翻译：紧致荧光内窥镜视频系统
公开(公告)号：US20080228037A1
公开(公告)日：2008-09-18
申请号：US11969974
申请日：2008-01-07
申请人： Richard W. Cline , John J.P. Fengler , Joachim W. Boehm
发明人： Richard W. Cline , John J.P. Fengler , Joachim W. Boehm
IPC分类号： A61B1/04
CPC分类号： A61B5/0071 , A61B1/00009 , A61B1/00057 , A61B1/00186 , A61B1/041 , A61B1/043 , A61B1/045 , A61B1/051 , A61B1/06 , A61B1/063 , A61B1/0638 , A61B1/0646 , A61B1/0669 , A61B1/2676 , A61B5/0084 , G01N21/6458 , G06F19/00
摘要： A fluorescence endoscopy video system includes a multimode light source that produces light for color and fluorescence imaging modes. Light from the light source is transmitted through an endoscope to the tissue under observation. The system also includes a compact camera for color and fluorescence imaging. Images obtained through the endoscope are optically divided and projected onto one or more image sensors by a fixed beam splitter in the camera. The fixed beam splitter eliminates the need for inserting a movable mirror into the light path between the endoscope and the image sensors. Image signals from the camera are processed in the system processor/controller where a contrast enhancement function can be applied. The contrast enhancement function increases the color contrast between normal tissue and tissue suspicious for early cancer. Finally, the system also includes a calibration feature whereby the system performance can be maintained when used with different endoscopes.
摘要翻译：荧光内窥镜视频系统包括产生用于彩色和荧光成像模式的光的多模光源。来自光源的光通过内窥镜透射到观察的组织。该系统还包括一个用于彩色和荧光成像的小型相机。通过内窥镜获得的图像通过照相机中的固定分束器被光学分割并投影到一个或多个图像传感器上。固定分束器不需要将可移动反射镜插入到内窥镜和图像传感器之间的光路中。来自相机的图像信号在可应用对比度增强功能的系统处理器/控制器中进行处理。对比度增强功能增加了早期癌症可疑的正常组织和组织之间的颜色对比。最后，该系统还包括校准特征，从而当与不同的内窥镜一起使用时可以维持系统性能。

3. 发明申请

US20100210904A1 COMPACT FLUORESCENCE ENDOSCOPY VIDEO SYSTEM 有权
标题翻译：紧致荧光内窥镜视频系统
公开(公告)号：US20100210904A1
公开(公告)日：2010-08-19
申请号：US12761462
申请日：2010-04-16
申请人： Richard W. Cline , John J.P. Fengler , Joachim W. Boehm
发明人： Richard W. Cline , John J.P. Fengler , Joachim W. Boehm
IPC分类号： A61B1/04
CPC分类号： A61B5/0071 , A61B1/00009 , A61B1/00057 , A61B1/00186 , A61B1/041 , A61B1/043 , A61B1/045 , A61B1/051 , A61B1/06 , A61B1/063 , A61B1/0638 , A61B1/0646 , A61B1/0669 , A61B1/2676 , A61B5/0084 , G01N21/6458 , G06F19/00
摘要： A fluorescence endoscopy video system includes a multimode light source that produces light for color and fluorescence imaging modes. Light from the light source is transmitted through an endoscope to the tissue under observation. The system also includes a compact camera for color and fluorescence imaging. Images obtained through the endoscope are optically divided and projected onto one or more image sensors by a fixed beam splitter in the camera. The fixed beam splitter eliminates the need for inserting a movable mirror into the light path between the endoscope and the image sensors. Image signals from the camera are processed in the system processor/controller where a contrast enhancement function can be applied. The contrast enhancement function increases the color contrast between normal tissue and tissue suspicious for early cancer. Finally, the system also includes a calibration feature whereby the system performance can be maintained when used with different endoscopes.
摘要翻译：荧光内窥镜视频系统包括产生用于彩色和荧光成像模式的光的多模光源。来自光源的光通过内窥镜透射到观察的组织。该系统还包括一个用于彩色和荧光成像的小型相机。通过内窥镜获得的图像通过照相机中的固定分束器被光学分割并投影到一个或多个图像传感器上。固定分束器不需要将可移动反射镜插入到内窥镜和图像传感器之间的光路中。来自相机的图像信号在可应用对比度增强功能的系统处理器/控制器中进行处理。对比度增强功能增加了早期癌症可疑的正常组织和组织之间的颜色对比。最后，该系统还包括校准特征，从而当与不同的内窥镜一起使用时可以维持系统性能。

4. 发明申请

US20100198010A1 COMPACT FLUORESCENCE ENDOSCOPY VIDEO SYSTEM 审中-公开
公开(公告)号：US20100198010A1
公开(公告)日：2010-08-05
申请号：US12761523
申请日：2010-04-16
申请人： Richard W. Cline , John J.P. Fengler , Joachim W. Boehm
发明人： Richard W. Cline , John J.P. Fengler , Joachim W. Boehm
IPC分类号： A61B1/04
CPC分类号： A61B5/0071 , A61B1/00009 , A61B1/00057 , A61B1/00186 , A61B1/041 , A61B1/043 , A61B1/045 , A61B1/051 , A61B1/06 , A61B1/063 , A61B1/0638 , A61B1/0646 , A61B1/0669 , A61B1/2676 , A61B5/0084 , G01N21/6458 , G06F19/00 , G16Z99/00
摘要： A fluorescence endoscopy video system includes a multimode light source that produces light for color and fluorescence imaging modes. Light from the light source is transmitted through an endoscope to the tissue under observation. The system also includes a compact camera for color and fluorescence imaging. Images obtained through the endoscope are optically divided and projected onto one or more image sensors by a fixed beam splitter in the camera. The fixed beam splitter eliminates the need for inserting a movable mirror into the light path between the endoscope and the image sensors. Image signals from the camera are processed in the system processor/controller where a contrast enhancement function can be applied. The contrast enhancement function increases the color contrast between normal tissue and tissue suspicious for early cancer. Finally, the system also includes a calibration feature whereby the system performance can be maintained when used with different endoscopes.

5. 发明授权

US07341557B2 Compact fluorescence endoscopy video system 有权
标题翻译：紧凑型荧光内窥镜视频系统
公开(公告)号：US07341557B2
公开(公告)日：2008-03-11
申请号：US10899648
申请日：2004-07-26
申请人： Richard W. Cline , John J. P. Fengler , Joachim W. Boehm
发明人： Richard W. Cline , John J. P. Fengler , Joachim W. Boehm
IPC分类号： A61B1/04
CPC分类号： A61B5/0071 , A61B1/00009 , A61B1/00057 , A61B1/00186 , A61B1/041 , A61B1/043 , A61B1/045 , A61B1/051 , A61B1/06 , A61B1/063 , A61B1/0638 , A61B1/0646 , A61B1/0669 , A61B1/2676 , A61B5/0084 , G01N21/6458 , G06F19/00
摘要： A fluorescence endoscopy video system includes a multimode light source that produces light for color and fluorescence imaging modes. Light from the light source is transmitted through an endoscope to the tissue under observation. The system also includes a compact camera for color and fluorescence imaging. Images obtained through the endoscope are optically divided and projected onto one or more image sensors by a fixed beam splitter in the camera. The fixed beam splitter eliminates the need for inserting a movable mirror into the light path between the endoscope and the image sensors. Image signals from the camera are processed in the system processor/controller where a contrast enhancement function can be applied. The contrast enhancement function increases the color contrast between normal tissue and tissue suspicious for early cancer. Finally, the system also includes a calibration feature whereby the system performance can be maintained when used with different endoscopes.
摘要翻译：荧光内窥镜视频系统包括产生用于彩色和荧光成像模式的光的多模光源。来自光源的光通过内窥镜透射到观察的组织。该系统还包括一个用于彩色和荧光成像的小型相机。通过内窥镜获得的图像通过照相机中的固定分束器被光学分割并投影到一个或多个图像传感器上。固定分束器不需要将可移动反射镜插入到内窥镜和图像传感器之间的光路中。来自相机的图像信号在可应用对比度增强功能的系统处理器/控制器中进行处理。对比度增强功能增加了早期癌症可疑的正常组织和组织之间的颜色对比。最后，该系统还包括校准特征，从而当与不同的内窥镜一起使用时可以维持系统性能。

6. 发明授权

US06821245B2 Compact fluorescence endoscopy video system 有权
标题翻译：紧凑型荧光内窥镜视频系统
公开(公告)号：US06821245B2
公开(公告)日：2004-11-23
申请号：US09905642
申请日：2001-07-13
申请人： Richard W. Cline , John J. P. Fengler , Joachim W. Boehm
发明人： Richard W. Cline , John J. P. Fengler , Joachim W. Boehm
IPC分类号： A61B104
CPC分类号： A61B5/0071 , A61B1/00009 , A61B1/00057 , A61B1/00186 , A61B1/041 , A61B1/043 , A61B1/045 , A61B1/051 , A61B1/06 , A61B1/063 , A61B1/0638 , A61B1/0646 , A61B1/0669 , A61B1/2676 , A61B5/0084 , G01N21/6458 , G06F19/00
摘要： A fluorescence endoscopy video system includes a multimode light source that produces light for color and fluorescence imaging modes. Light from the light source is transmitted through an endoscope to the tissue under observation. The system also includes a compact camera for color and fluorescence imaging. Images obtained through the endoscope are optically divided and projected onto one or more image sensors by a fixed beam splitter in the camera. The fixed beam splitter eliminates the need for inserting a movable mirror into the light path between the endoscope and the image sensors. Image signals from the camera are processed in the system processor/controller where a contrast enhancement function can be applied. The contrast enhancement function increases the color contrast between normal tissue and tissue suspicious for early cancer. Finally, the system also includes a calibration feature whereby the system performance can be maintained when used with different endoscopes.
摘要翻译：荧光内窥镜视频系统包括产生用于彩色和荧光成像模式的光的多模光源。来自光源的光通过内窥镜透射到观察的组织。该系统还包括一个用于彩色和荧光成像的小型相机。通过内窥镜获得的图像通过照相机中的固定分束器被光学分割并投影到一个或多个图像传感器上。固定分束器不需要将可移动反射镜插入到内窥镜和图像传感器之间的光路中。来自相机的图像信号在可应用对比度增强功能的系统处理器/控制器中进行处理。对比度增强功能增加了早期癌症可疑的正常组织和组织之间的颜色对比。最后，该系统还包括校准特征，从而当与不同的内窥镜一起使用时可以维持系统性能。

7. 发明授权

US07722534B2 Compact fluorescence endoscopy video system 有权
标题翻译：紧凑型荧光内窥镜视频系统
公开(公告)号：US07722534B2
公开(公告)日：2010-05-25
申请号：US11969974
申请日：2008-01-07
申请人： Richard W Cline , John J. P. Fengler , Joachim W. Boehm
发明人： Richard W Cline , John J. P. Fengler , Joachim W. Boehm
IPC分类号： A61B1/04
CPC分类号： A61B5/0071 , A61B1/00009 , A61B1/00057 , A61B1/00186 , A61B1/041 , A61B1/043 , A61B1/045 , A61B1/051 , A61B1/06 , A61B1/063 , A61B1/0638 , A61B1/0646 , A61B1/0669 , A61B1/2676 , A61B5/0084 , G01N21/6458 , G06F19/00
摘要： A fluorescence endoscopy video system includes a multimode light source that produces light for color and fluorescence imaging modes. Light from the light source is transmitted through an endoscope to the tissue under observation. The system also includes a compact camera for color and fluorescence imaging. Images obtained through the endoscope are optically divided and projected onto one or more image sensors by a fixed beam splitter in the camera. The fixed beam splitter eliminates the need for inserting a movable mirror into the light path between the endoscope and the image sensors. Image signals from the camera are processed in the system processor/controller where a contrast enhancement function can be applied. The contrast enhancement function increases the color contrast between normal tissue and tissue suspicious for early cancer. Finally, the system also includes a calibration feature whereby the system performance can be maintained when used with different endoscopes.
摘要翻译：荧光内窥镜视频系统包括产生用于彩色和荧光成像模式的光的多模光源。来自光源的光通过内窥镜透射到观察的组织。该系统还包括一个用于彩色和荧光成像的小型相机。通过内窥镜获得的图像通过照相机中的固定分束器被光学分割并投影到一个或多个图像传感器上。固定分束器不需要将可移动反射镜插入到内窥镜和图像传感器之间的光路中。来自相机的图像信号在可应用对比度增强功能的系统处理器/控制器中进行处理。对比度增强功能增加了早期癌症可疑的正常组织和组织之间的颜色对比。最后，该系统还包括校准特征，从而当与不同的内窥镜一起使用时可以维持系统性能。

8. 发明授权

US07420151B2 Device for short wavelength visible reflectance endoscopy using broadband illumination 有权
标题翻译：使用宽带照明的短波长可见反射内窥镜检查装置
公开(公告)号：US07420151B2
公开(公告)日：2008-09-02
申请号：US11546013
申请日：2006-10-10
申请人： John J. P. Fengler , Paul R. Westwick , Joachim W. Boehm
发明人： John J. P. Fengler , Paul R. Westwick , Joachim W. Boehm
IPC分类号： A61B1/04
CPC分类号： A61B1/00009 , A61B1/00186 , A61B5/0084
摘要： A system for performing short wavelength imaging with a broadband illumination source includes an image processor that receives signals from a color image sensor. The image processor reduces the contribution of red illumination light to an image by computing blue, green, and blue-green (cyan) color components of display pixels from the signals received from the image sensor. The blue, green, and cyan color component values are coupled to inputs of a color monitor for display to produce a false color image of the tissue.
摘要翻译：用宽带照明源执行短波长成像的系统包括从彩色图像传感器接收信号的图像处理器。图像处理器通过从从图像传感器接收的信号计算显示像素的蓝色，绿色和蓝色（青色）颜色分量来减少红色照明光对图像的贡献。蓝色，绿色和青色颜色分量值耦合到用于显示的彩色监视器的输入以产生组织的假彩色图像。

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