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1. 发明授权

US10780057B2 Casein-based silica dual drug-loading composite microcapsule and preparation method therefor 有权
公开(公告)号：US10780057B2
公开(公告)日：2020-09-22
申请号：US16348873
申请日：2017-01-13
申请人： SHAANXI UNIVERSITY OF SCIENCE & TECHNOLOGY , Jianzhong Ma , Qianqian Fan , Qunna Xu
发明人： Jianzhong Ma , Qianqian Fan , Qunna Xu
IPC分类号： A61K9/50 , A61K47/02 , A61K47/24
摘要： This invention presents a method for preparing casein-based silica dual drug-loaded composite microcapsule. Recently, casein has shown good application prospects in the field of medicine due to its good biocompatibility and unique cavity structure. However, research on preparation of casein-based dual drug-loaded microcapsules is still rarely reported. In this invention, dual drug-loaded casein microcapsules is obtained via interfacial polymerization method, where drug-loaded casein can be used as outer shell material in capsule, and silica is served as inner shell in the capsule. In the obtained microcapsule, drugs can not only be loaded in the inner cavity, but also in casein shell. Application of the dual drug-loaded microcapsules in the treatment of diseases is expected to reduce the number of dose to a certain extent and improve the therapeutic effect.

2. 发明申请

US20130099403A1 SEMEN CASSIAE SOFT CAPSULE FOR REDUCING FAT AND LOSING WEIGHT AND PREPARATION METHOD THEREOF 有权
标题翻译：用于减少脂肪和失重的SEMEN CASSIAE软胶囊及其制备方法
公开(公告)号：US20130099403A1
公开(公告)日：2013-04-25
申请号：US13806109
申请日：2011-06-28
申请人： Jianzhong Ma
发明人： Jianzhong Ma
IPC分类号： A61K9/48 , A61K36/482 , A61K36/185
CPC分类号： A61K9/4833 , A61K9/2086 , A61K9/2095 , A61K9/4875 , A61K36/185 , A61K36/482 , A61K36/484 , A61K36/61 , A61K2300/00
摘要： A Semen Cassiae soft capsule for lowering blood lipids and losing weight and the preparation method thereof. The content of the soft capsule consist of the following components by weight part: 10-60 parts of ethanol soluble extract powder of Semen Cassiae, 2-10 parts of aqueous soluble extract powder of Radix Glycyrrhizae, 10-30 parts of evening primrose oil, 5-20 parts of sea buckthorn seed oil and 2-10 parts of beeswax. The preparation method includes the following steps: preparing all the components respectively; dissolving the ethanol soluble extract powder of Semen Cassiae in ethanol, adding 50% of the total weight of beeswax, heating in a water bath at 75 degrees Celsius to obtain a liquid mixture of Semen Cassiae and beeswax; heating the remainder beeswax with evening primrose oil, adding the liquid mixture of Semen Cassiae and beeswax while continuously stirring, adding aqueous soluble extract powder of Radix Glycyrrhizae, cooling the mixture by circulation water, adding sea buckthorn seed oil and continuously stirring to obtain the content for soft capsules, encapsulating soft capsules by conventional method to obtain the Semen Cassiae soft capsule.
摘要翻译：一种用于降低血脂和减肥的精油仙人掌软胶囊及其制备方法。软胶囊的含量由以下重量份组成：10-60份精油乙醇可溶性提取物粉末，2-10份甘草水溶性提取物粉末，月见草油10-30份， 5-20份沙棘籽油和2-10份蜂蜡。制备方法包括以下步骤：分别制备所有组分; 将乙酸可溶性提取物粉末溶解在乙醇中，加入蜂蜡总重量的50％，在75℃的水浴中加热，得到精油和蜂蜡的液体混合物; 用月见草油加热剩余的蜂蜡，在连续搅拌下加入精油和蜂蜡的液体混合物，加入甘草水溶性提取物粉末，循环水冷却混合物，加入沙棘籽油，连续搅拌，得到含量对于软胶囊，通过常规方法包封软胶囊以获得仙客来软胶囊。

3. 发明授权

US08859006B2 Semen cassiae soft capsule for reducing fat and losing weight and preparation method thereof 有权
标题翻译：用于减肥和减肥的精肉桂软胶囊及其制备方法
公开(公告)号：US08859006B2
公开(公告)日：2014-10-14
申请号：US13806109
申请日：2011-06-28
申请人： Jianzhong Ma
发明人： Jianzhong Ma
IPC分类号： A61K35/64 , A61K36/484 , A61K36/18 , A61K9/48 , A61K36/61 , A61K36/482 , A61K36/185 , A61K9/20
CPC分类号： A61K9/4833 , A61K9/2086 , A61K9/2095 , A61K9/4875 , A61K36/185 , A61K36/482 , A61K36/484 , A61K36/61 , A61K2300/00
摘要： A Semen Cassiae soft capsule for lowering blood lipids and losing weight and the preparation method thereof. The content of the soft capsule consist of the following components by weight part: 10-60 parts of ethanol soluble extract powder of Semen Cassiae, 2-10 parts of aqueous soluble extract powder of Radix Glycyrrhizae, 10-30 parts of evening primrose oil, 5-20 parts of sea buckthorn seed oil and 2-10 parts of beeswax. The preparation method includes the following steps: preparing all the components respectively; dissolving the ethanol soluble extract powder of Semen Cassiae in ethanol, adding 50% of the total weight of beeswax, heating in a water bath at 75 degrees Celsius to obtain a liquid mixture of Semen Cassiae and beeswax; heating the remainder beeswax with evening primrose oil, adding the liquid mixture of Semen Cassiae and beeswax while continuously stirring, adding aqueous soluble extract powder of Radix Glycyrrhizae, cooling the mixture by circulation water, adding sea buckthorn seed oil and continuously stirring to obtain the content for soft capsules, encapsulating soft capsules by conventional method to obtain the Semen Cassiae soft capsule.
摘要翻译：一种用于降低血脂和减肥的精油仙人掌软胶囊及其制备方法。软胶囊的含量由以下重量份组成：10-60份精油乙醇可溶性提取物粉末，2-10份甘草水溶性提取物粉末，月见草油10-30份， 5-20份沙棘籽油和2-10份蜂蜡。制备方法包括以下步骤：分别制备所有组分; 将乙酸可溶性提取物粉末溶解在乙醇中，加入蜂蜡总重量的50％，在75℃的水浴中加热，得到精油和蜂蜡的液体混合物; 用月见草油加热剩余的蜂蜡，在连续搅拌下加入精油和蜂蜡的液体混合物，加入甘草水溶性提取物粉末，循环水冷却混合物，加入沙棘籽油，连续搅拌，得到含量对于软胶囊，通过常规方法包封软胶囊以获得仙客来软胶囊。

4. 发明申请

US20070036101A1 Distributed node B module 审中-公开
标题翻译：分布式节点B模块
公开(公告)号：US20070036101A1
公开(公告)日：2007-02-15
申请号：US11451957
申请日：2006-06-13
申请人： Fumin Chen , Xufan She , Jianzhong Ma
发明人： Fumin Chen , Xufan She , Jianzhong Ma
IPC分类号： H04Q7/00
CPC分类号： H04W88/08
摘要： The present invention discloses a distributed Node B module which is used for containing a remote radio unit of a distributed Node B. Said module includes a roughly cuboid module body, an outlet chamber arranged at one lateral side of the module body, and a plurality of outlet connectors arranged at the bottom side of which module body. The present invention employs a combination of the bottom outlet connectors and the lateral outlet chamber, which makes a reasonable utilization of the structure, increases the density of outlets in a better way. In the case of equivalent outlet density, the volume and the weight of the module can be decreased, and the networking becomes more convenient and flexible.
摘要翻译：本发明公开了一种用于包含分布式节点B的远程无线电单元的分布式节点B模块。所述模块包括粗略长方体模块主体，布置在模块主体的一个侧面的出口室，以及多个出口连接器布置在其模块体的底侧。本发明采用底部出口连接器和侧向出口室的组合，这使得结构的合理利用更好地增加了出口的密度。在等效出口密度的情况下，可以减小模块的体积和重量，网络变得更加方便灵活。

5. 发明授权

US10676798B2 Poly-octavinyl polyhedral oligomeric silsesquioxane-acrylic acid nano composite auxiliary agent for leather and preparation method therefor 有权
公开(公告)号：US10676798B2
公开(公告)日：2020-06-09
申请号：US16348874
申请日：2017-01-13
申请人： SHAANXI UNIVERSITY OF SCIENCE & TECHNOLOGY , Jianzhong Ma , Lu Jia , Dangge Gao , Bin Lv
发明人： Jianzhong Ma , Lu Jia , Dangge Gao , Bin Lv
IPC分类号： C14C3/22 , C08F220/06 , C08G77/04 , C08F230/08 , B82Y35/00
摘要： The invention relates to a poly silsesquioxane-acrylic nanocomposite auxiliary for leather process and its preparation method. By mixing octavinyl silsesquioxane, organic solvent, ammonium persulfate, distilled water and surfactant in one system, and adding acrylic acid dropwise into the mixing system, cooling to adjust pH to obtain poly silsesquioxane-acrylic nanocomposite auxiliary for leather process. The auxiliary obtained in this invention is easily to penetrate into gap of the collagen fibers, and forms nano and micro-scale combination with the leather collagen, which can further improve the multi-point combination of the acrylic polymer with the collagen. Thus, the filling property of the leather that treated by the auxiliary is improved without affect the yield of leather, and the chromium content in the waste water is significantly reduced.

6. 发明申请

US20170137903A1 SULFONATOCALIXARENE TANNING AGENT FOR LEATHER TANNING AND PREPARATION METHOD THEREFOR 有权
公开(公告)号：US20170137903A1
公开(公告)日：2017-05-18
申请号：US15322219
申请日：2015-06-18
申请人： Jianzhong MA , Yongxiang ZHOU , Dangge GAO , Panpan ZHANG , Bin LV , SHAANXI UNIVERSITY OF SCIENCE & TECHNOLOGY
发明人： Jianzhong MA , Yongxiang ZHOU , Dangge GAO , Panpan ZHANG , Bin LV
IPC分类号： C14C3/20
CPC分类号： C14C3/20 , C08G8/04 , C08G8/28
摘要： A sulfonatocalixarene tanning agent for leather tanning and a preparation method comprises: using resorcinol and aldehyde monomers as raw materials for the tanning agent; adding an ethanol solution into the resorcinol, dropwise adding an inorganic strong acid catalyst and aldehyde derivatives, heating to react, cooling, carrying out suction filtration, repeatedly washing with ethanol and distilled water, and drying to obtain resorcinol calixarene; and weighing the resorcinol calixarene, and adding a sulfonating agent to react, thereby obtaining a sulfonatocalixarene tanning agent aqueous solution.

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