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    • 3. 发明申请
    • METHOD FOR MANUFACTURING A SILICA POWDER COATED WITH AN ANTIBACTERIAL AGENT, AND TOPICAL DERMATOLOGICAL COMPOSITION INCLUDING THE SAME
    • 制造涂有抗菌剂的二氧化硅粉末的方法和包括其的局部皮肤组合物
    • US20120237582A1
    • 2012-09-20
    • US13512837
    • 2009-12-11
    • Youn-kyung DoYun-jeong KimJi-hyun SonHyun-sang LeeJong-woo Cheon
    • Youn-kyung DoYun-jeong KimJi-hyun SonHyun-sang LeeJong-woo Cheon
    • A61K8/02A61Q19/00B05D5/00B82Y40/00B82Y30/00
    • A61K9/0014A61K8/0241A61K8/19A61K8/25A61K9/1611A61K9/167A61K2800/412A61K2800/621A61Q17/005A61Q19/00
    • Provided are a method of preparing a silica powder coated with an antibacterial agent and a topical dermatological composition including the silica powder, and more particularly, a method of preparing a silica powder coated with an antibacterial agent by forming a silica particle by inducing a reaction between silicon alkoxide and alcohol solvent in the presence of a catalyst and then forming an silver and metallic coating layer on the silica particle, and a method of preparing a topical dermatological composition including the silica powder. The silica powder coated with the antibacterial agent may have high antibacterial capability, and thus, topical dermatological products including the silica powder may be maintained for a long time without using a chemical antiseptic agent that may irritate the skin and cause an allergy in the human body. Even if a small amount of expensive silver (Ag) ion material is used, the silica powder has excellent antibacterial capability and stability. In addition, since the silica powder exhibits bright color, colors may be freely expressed when used in a composition of cosmetics, and thus, there is no is limit in using the silica powder in bright-color cosmetics as well as in dark-color cosmetics.
    • 提供一种制备涂覆有抗菌剂的二氧化硅粉末和包含二氧化硅粉末的局部皮肤病学组合物的方法,更具体地,涉及一种通过形成二氧化硅颗粒通过诱导二氧化硅颗粒之间的反应来制备涂覆有抗菌剂的二氧化硅粉末的方法 硅烷醇盐和醇溶剂,然后在二氧化硅颗粒上形成银和金属涂层,以及制备包含二氧化硅粉末的局部皮肤病学组合物的方法。 涂有抗菌剂的二氧化硅粉末可能具有高的抗菌能力,因此可以长期保持包括二氧化硅粉末在内的局部皮肤病学产品,而不使用可能刺激皮肤并在人体中引起过敏的化学防腐剂 。 即使使用少量昂贵的银(Ag)离子材料,二氧化硅粉末具有优异的抗菌能力和稳定性。 此外,由于二氧化硅粉末显示出鲜艳的颜色,因此在化妆品组合物中使用时可以自由表现颜色,因此在亮色化妆品以及深色化妆品中使用二氧化硅粉末没有限制 。