专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US08236945B2 Process for preparing disulfides and thiosulphinates and compounds prepared 失效
标题翻译：制备二硫化物和硫代硫酸盐和化合物的方法
公开(公告)号：US08236945B2
公开(公告)日：2012-08-07
申请号：US12298156
申请日：2007-04-24
申请人： Jean-Luc Decout , Beatrice Gerland , Jerome Desire
发明人： Jean-Luc Decout , Beatrice Gerland , Jerome Desire
IPC分类号： A61K31/7068 , A61K31/7072 , C07H19/06 , C07H19/067 , C07H19/073
CPC分类号： C07D405/04 , C07F7/0812 , C07F7/1804 , C07H19/06
摘要： Process for preparing a compound of the formula (I) R1-S(O)x—S(O)yR2 in which R1 represents a molecular hydrocarbon radical which can be substituted and/or interrupted by one or more atoms and/or by one or more groups containing one or more atoms, said atoms being selected from N, O, P, S, Si and X, where X represents a halogen; R2, independently of R1, represents a carbon-containing group or a molecular hydrocarbon radical which can be substituted and/or interrupted by one or more atoms and/or by one or more groups containing one or more atoms, said atoms being selected from N, O, P, S, Si and X, where X represents a halogen, and x and y are selected from 0 and 1 in such a way that the sum of x and y is not more than 1, characterized in that a compound of formula (II) R1-S(O)x—R3-Si(R4)(R5)(R6) in which R3 represents a hydrocarbon chain of two carbon atoms, which is optionally unsaturated and/or substituted, and R4, R5 and R6, which are identical or different, each represent, independently of one another, a hydrocarbon group, is reacted with a compound of formula (VII) R2-S(O)y—X in which X represents a halogen, intermediate compounds, and compounds prepared.
摘要翻译：制备式（I）化合物的方法R 1 -S（O）x -S（O）y R 2，其中R 1表示可被一个或多个原子和/或一个或多个原子取代和/或中断的分子烃基或更多个含有一个或多个原子的基团，所述原子选自N，O，P，S，Si和X，其中X表示卤素; R2独立地表示可以被一个或多个原子和/或一个或多个含有一个或多个原子的基团取代和/或中断的含碳基团或分子烃基，所述原子选自N ，O，P，S，Si和X，其中X表示卤素，x和y选自0和1，使得x和y之和不大于1，其特征在于，化合物式（II）R1-S（O）x-R3-Si（R4）（R5）（R6），其中R3表示任选不饱和和/或取代的两个碳原子的烃链，R4，R5和 R 6相同或不同，各自独立地表示烃基，与式（Ⅶ）化合物R-S（O）y -X化合，其中X表示卤素，中间体化合物和化合物制备。

2. 发明授权

US08729035B2 Synthesis of novel neamine derivatives and use thereof as antibacterial agents 有权
标题翻译：新型神经胺衍生物的合成及其作为抗菌剂的用途
公开(公告)号：US08729035B2
公开(公告)日：2014-05-20
申请号：US12735511
申请日：2009-01-22
申请人： Jean-Luc Decout , Isabelle Baussanne , Jerome Desire , Jean-Marc Paris
发明人： Jean-Luc Decout , Isabelle Baussanne , Jerome Desire , Jean-Marc Paris
IPC分类号： A61K31/70 , C07H15/20 , C07H15/22
CPC分类号： C07H15/224
摘要： This invention concerns compounds with the formula: in which: R1═OH or NH2; OR2, OR3, OR4 and OR5 are alcohol, ether, ester, carbonate, carbamate, sulphonate or sulphamate groups; and if R5═H if R2═R3═R4, then R2, R3 and R4≠H; if R2═H, then R3≠H and R4≠H; if R3═H, then R2≠H and R4≠H; if R4═H, then R2≠H and R3≠H; if R5≠H if R2=H, then R3≠H and R4≠H; if R3═H, then R2≠H and R4≠H; if R4═H, then R2≠H and R3≠H, their use as antibiotic agents and the process for synthesizing them.
摘要翻译：本发明涉及下式的化合物：其中：R1 = OH或NH2; OR2，OR3，OR4和OR5是醇，醚，酯，碳酸酯，氨基甲酸酯，磺酸酯或氨基磺酸酯基团; 如果R 2 = R 3 = R 4，如果R 5为H，那么R 2，R 3和R 4≠H; 如果R2 = H，则R3≠H，R4≠H; 如果R3 = H，则R2≠H，R4≠H; 如果R4 = H，则R2≠H，R3≠H; 如果R2 = H，则R5≠H，则R3≠H，R4≠H; 如果R3 = H，则R2≠H，R4≠H; 如果R4 = H，那么R2≠H，R3≠H，它们作为抗生素的用途和合成方法。

3. 发明申请

US20100311680A1 SYNTHESIS OF NOVEL NEAMINE DERIVATIVES AND USE THEREOF AS ANTIBACTERIAL AGENTS 有权
标题翻译：新型胺衍生物的合成及其作为抗菌剂的用途
公开(公告)号：US20100311680A1
公开(公告)日：2010-12-09
申请号：US12735511
申请日：2009-01-22
申请人： Jean-Luc Decout , Isabelle Baussane , Jerome Desire , Jean-Marc Paris
发明人： Jean-Luc Decout , Isabelle Baussane , Jerome Desire , Jean-Marc Paris
IPC分类号： A61K31/7036 , C07H15/224 , A61P31/00
CPC分类号： C07H15/224
摘要： This invention concerns compounds with the formula: in which: R1=OH or NH2; OR2, OR3, OR4 and OR5 are alcohol, ether, ester, carbonate, carbamate, sulphonate or sulphamate groups; and if R5=H if R2=R3=R4, then R2, R3 and R4≠H; if R2=H, then R3≠H and R4≠H; if R3=H, then R2≠H and R4≠H; if R4=H, then R2≠H and R3≠H; if R5≠H if R2=H, then R3≠H and R4≠H; if R3=H, then R2≠H and R4≠H; if R4=H, then R2≠H and R3≠H, their use as antibiotic agents and the process for synthesising them.
摘要翻译：本发明涉及具有下式的化合物：其中：R1 = OH或NH2; OR2，OR3，OR4和OR5是醇，醚，酯，碳酸酯，氨基甲酸酯，磺酸酯或氨基磺酸酯基团; 如果R 2 = R 3 = R 4，如果R 5 = H，则R 2，R 3和R 4≠H; 如果R2 = H，则R3≠H，R4≠H; 如果R3 = H，则R2≠H，R4≠H; 如果R4 = H，则R2≠H，R3≠H; 如果R2 = H，则R5≠H，则R3≠H，R4≠H; 如果R3 = H，则R2≠H，R4≠H; 如果R4 = H，那么R2≠H，R3≠H，它们作为抗生素的用途和合成方法。

4. 发明申请

US20100075917A1 THIONUCLEOSIDES AND PHARMACEUTICAL APPLICATIONS 审中-公开
标题翻译：噻唑类和药物应用
公开(公告)号：US20100075917A1
公开(公告)日：2010-03-25
申请号：US12447346
申请日：2007-10-29
申请人： Jean-Luc Decout , Beatrice Gerland , Jerome Desire , Michel Lepoivre , Jan Balzarini
发明人： Jean-Luc Decout , Beatrice Gerland , Jerome Desire , Michel Lepoivre , Jan Balzarini
IPC分类号： A61K31/7064 , C07H19/06 , A61P35/00 , A61P31/18
CPC分类号： C07D405/04 , C07H19/00 , C07H19/06 , C07H19/067 , C07H19/073 , C07H19/173
摘要： The invention relates to a pharmaceutical composition containing as an active ingredient at least one compound selected from the compounds of the formula (II), in which the S atom is bonded to the nucleoside carbon at T or to the nucleoside carbon at 3′, and from the compounds of the following formula (III): formulae in which B is a nucleotide natural or modified base, x is 0, 1 or 2, and R1 and R represent a carbonated group or a molecular hydrocarbon remnant that can be substituted and/or interrupted by one or more atoms and/or by one or more groups containing one or more atoms, said atoms being selected from N, O, P, S, Si, X where X is halogen. The invention also relates to pharmaceutically acceptable carrier.
摘要翻译：本发明涉及一种药物组合物，其含有至少一种选自式（II）化合物中的至少一种化合物，其中S原子在T处与核苷碳键合或在3'与核苷碳结合，以及由下式（III）的化合物：其中B是核苷酸天然或修饰碱基的式，x是0,1或2，R1和R表示可被取代的碳酸化基团或分子碳氢化合物残余物，和/ 或被一个或多个原子和/或被一个或多个含有一个或多个原子的基团中断，所述原子选自N，O，P，S，Si，X，其中X是卤素。本发明还涉及药学上可接受的载体。

5. 发明申请

US20090264637A1 PROCESS FOR PREPARING DISULPHIDES AND THIOSULPHINATES AND COMPOUNDS PREPARED 失效
标题翻译：制备疏水性和硫代磷酸酯和化合物的方法
公开(公告)号：US20090264637A1
公开(公告)日：2009-10-22
申请号：US12298156
申请日：2007-04-24
申请人： Jean-Luc Decout , Beatrice Gerland , Jerome Desire
发明人： Jean-Luc Decout , Beatrice Gerland , Jerome Desire
IPC分类号： C07H19/06
CPC分类号： C07D405/04 , C07F7/0812 , C07F7/1804 , C07H19/06
摘要： Process for preparing a compound of the formula (I) R1-S(O)x—S(O)yR2 in which R1 represents a molecular hydrocarbon radical which can be substituted and/or interrupted by one or more atoms and/or by one or more groups containing one or more atoms, said atoms being selected from N, O, P, S, Si and X, where X represents a halogen; R2, independently of R1, represents a carbon-containing group or a molecular hydrocarbon radical which can be substituted and/or interrupted by one or more atoms and/or by one or more groups containing one or more atoms, said atoms being selected from N, O, P, S, Si and X, where X represents a halogen, and x and y are selected from 0 and 1 in such a way that the sum of x and y is not more than 1, characterized in that a compound of formula (II) R1-S(O)x—R3-Si(R4)(R5)(R6) in which R3 represents a hydrocarbon chain of two carbon atoms, which is optionally unsaturated and/or substituted, and R4, R5 and R6, which are identical or different, each represent, independently of one another, a hydrocarbon group, is reacted with a compound of formula (VII) R2-S(O)y—X in which X represents a halogen, intermediate compounds, and compounds prepared.
摘要翻译：制备式（I）化合物的方法R 1 -S（O）x S（O）y R 2，其中R 1表示可以被一个或多个原子取代和/或中断的分子烃基和/或一个或多个含有一个或多个原子的基团，所述原子选自N，O，P，S，Si和X，其中X表示卤素; R2独立地表示可以被一个或多个原子和/或一个或多个含有一个或多个原子的基团取代和/或中断的含碳基团或分子烃基，所述原子选自N ，O，P，S，Si和X，其中X表示卤素，x和y选自0和1，使得x和y之和不大于1，其特征在于，化合物式（II）R1-S（O）x-R3-Si（R4）（R5）（R6），其中R3表示任选不饱和和/或取代的两个碳原子的烃链，R4，R5和 R6相同或不同，各自独立地表示烃基，其中X表示卤素，中间体化合物和制备的化合物与式（Ⅶ）化合物R 2 -S（O）y X反应。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式