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1. 发明授权

US09151769B2 Automated calibration method and system for a diagnostic analyzer 有权
标题翻译：诊断分析仪的自动校准方法和系统
公开(公告)号：US09151769B2
公开(公告)日：2015-10-06
申请号：US13548769
申请日：2012-07-13
申请人： Jeremy Hammond , Dominic Pelletier , Jason Aguiar
发明人： Jeremy Hammond , Dominic Pelletier , Jason Aguiar
IPC分类号： G06F19/00 , G01N35/00
CPC分类号： G01N35/00693 , G01N2035/00702
摘要： An automated method for calibrating in real time a diagnostic analyzer includes the steps of receiving diagnostic results of patient samples calculated by the analyzer using pre-set parameters of the analyzer, and calculating the centroid of the analyzer's diagnostic results. The centroid of the analyzer's diagnostic results is subtracted from a centroid of diagnostic results of a field population of comparable analyzers to obtain a bias in the centroid of the analyzer's diagnostic results. The bias is compared to predetermined limits. Should the bias fall outside the predetermined limits, an optimization factor is derived and applied to the analyzer's diagnostic results to obtain optimized results from the analyzer without changing the pre-set parameters of the analyzer.
摘要翻译：用于实时校准诊断分析仪的自动化方法包括以下步骤：使用分析仪的预设参数来接收由分析仪计算的患者样品的诊断结果，以及计算分析仪诊断结果的质心。分析仪诊断结果的重心从相当分析仪的现场人群的诊断结果的重心中减去，以获得分析仪诊断结果的质心偏差。将偏差与预定极限相比较。如果偏差超出预定极限，则推导出优化因子并将其应用于分析仪的诊断结果，以便在不改变分析仪的预设参数的情况下从分析仪获得优化结果。

2. 发明授权

US07794664B2 Pipette tip 有权
标题翻译：移液器吸头
公开(公告)号：US07794664B2
公开(公告)日：2010-09-14
申请号：US11985439
申请日：2007-11-15
申请人： Dominic Pelletier , Jeffrey Phelps , Jason Aguiar , Jeremy Hammond , William J. Traigle , Chandler G. Sinnett
发明人： Dominic Pelletier , Jeffrey Phelps , Jason Aguiar , Jeremy Hammond , William J. Traigle , Chandler G. Sinnett
IPC分类号： B01L3/02
CPC分类号： B01L3/0275 , B01L3/0262 , B01L2200/141 , B01L2400/025
摘要： A pipette tip includes a main body having an upper end, a lower end and a sidewall extending between the two ends. A bore extends axially through the main body between the upper and lower ends. The lower end has a bottom surface in which is formed a central opening that communicates with the axial bore to allow the passage of fluid therethrough. The bottom surface is formed with at least one groove that may be concentrically disposed or spirally disposed about the central opening. The at least one groove acts to inhibit fluid passing through the central opening from at least partially flowing along the outer surface of the sidewall from the central opening toward the upper end of the main body of the pipette tip.
摘要翻译：移液管尖端包括具有上端，下端和在两端之间延伸的侧壁的主体。孔在上端和下端之间轴向延伸通过主体。下端具有底表面，其中形成有与轴向孔连通以允许流体通过的中心开口。底表面形成有至少一个凹槽，其可以围绕中心开口同心地设置或螺旋地设置。所述至少一个凹槽用于阻止流经中心开口的流体至少部分地沿着侧壁的外表面从中心开口朝向移液管尖端主体的上端流动。

3. 发明申请

US20080124276A1 Synthetic cornea from retinal stem cells 审中-公开
标题翻译：视网膜干细胞合成角膜
公开(公告)号：US20080124276A1
公开(公告)日：2008-05-29
申请号：US11584412
申请日：2006-10-19
申请人： Jeremy Hammond , Judy Kelleher-Andersson
发明人： Jeremy Hammond , Judy Kelleher-Andersson
IPC分类号： A61K49/00 , A01N1/00 , C12P1/04
CPC分类号： A61K35/30 , A61F2/142 , A61K35/12 , C12N5/0606 , C12N5/0621 , C12N5/0697 , C12N2500/32 , C12N2500/44 , C12N2501/115 , C12N2501/235 , C12N2501/999 , C12N2502/1323 , C12N2506/02 , C12N2506/04 , C12N2510/00 , C12N2533/50
摘要： Methods of producing synthetic corneas are disclosed which are differentiated from retinal stem cells (rSC) derived from parthenogenetically activated human oocytes, including that such synthetic corneas are produced in the absence of a 3-D scaffold. Isolated synthetic corneas, produced by the disclosed methods, are also described.
摘要翻译：公开了生产合成角膜的方法，其与衍生自孤雌激活的人卵母细胞的视网膜干细胞（rSC）分化，包括在没有3-D支架的情况下产生这样的合成角膜。还描述了通过公开的方法产生的分离的合成角膜。

4. 发明申请

US20050186889A1 WHEEL POLISHING DEVICE 失效
标题翻译：车轮抛光装置
公开(公告)号：US20050186889A1
公开(公告)日：2005-08-25
申请号：US10784133
申请日：2004-02-20
申请人： Gary McNeil , Jeremy Hammond
发明人： Gary McNeil , Jeremy Hammond
IPC分类号： B24B1/00 , B24B31/00 , B24C1/00 , B24C1/08
CPC分类号： B24B31/003
摘要： A device for finishing workpieces, such as automobile wheels. The device includes a bowl assembly containing polishing media therein, and a drive assembly including a rotatable turret which carries the wheels thereon so that same are orbitally driven through the polishing media. A cam arrangement is provided which essentially continuously adjusts the angle of the wheels relative to the polishing media by pivoting the wheels about respective vertical axes. The device is additionally provided with a vertical drive assembly which allows vertical oscillation of the wheels relative to the media, and the polishing device also permits adjustment of the pitch or rake angle of the wheels relative to the horizontal.
摘要翻译：用于完成工件的装置，例如汽车轮。该装置包括其中包含抛光介质的碗组件，以及包括可转动的转台的驱动组件，所述可转动的转台在其上承载有轮子，以便轨道驱动通过抛光介质。提供了一种凸轮装置，其通过围绕相应的垂直轴线枢转来基本上连续地调节车轮相对于抛光介质的角度。该装置另外设置有垂直驱动组件，其允许车轮相对于介质的垂直振动，并且抛光装置还允许相对于水平面调整车轮的间距或前角。

5. 发明申请

US20120005150A1 Automated calibration method and system for a diagnostic analyzer 有权
标题翻译：诊断分析仪的自动校准方法和系统
公开(公告)号：US20120005150A1
公开(公告)日：2012-01-05
申请号：US12932192
申请日：2011-02-18
申请人： Jeremy Hammond
发明人： Jeremy Hammond
IPC分类号： G06N7/02
CPC分类号： G01N35/00693 , G01N2035/00702
摘要： A method to track stability and performance of diagnostic instrumentation, especially for veterinary automated hematology analyzers, applies a weighted moving averages algorithm to the diagnostic results of patient samples calculated by the analyzer. Control chart rules are used to set limits or ranges in order to determine if weighted averaged diagnostic results are within or outside of such limits or ranges. If the weighted average diagnostic results are outside of such control chart rule limits, then fuzzy logic and a gradient descent algorithm are applied to the weighted averaged diagnostic results.
摘要翻译：用于跟踪诊断仪器的稳定性和性能的方法，特别是对于兽医自动血液分析仪，可以将加权移动平均值算法应用于由分析仪计算的患者样本的诊断结果。控制图规则用于设置限制或范围，以确定加权平均诊断结果是否在这些限制或范围之内或之外。如果加权平均诊断结果超出这种控制图规则限制，则将模糊逻辑和梯度下降算法应用于加权平均诊断结果。

6. 发明授权

US06960116B2 Wheel polishing device 失效
标题翻译：车轮抛光装置
公开(公告)号：US06960116B2
公开(公告)日：2005-11-01
申请号：US10784133
申请日：2004-02-20
申请人： Gary McNeil , Jeremy Hammond
发明人： Gary McNeil , Jeremy Hammond
IPC分类号： B24B1/00 , B24B31/00 , B24C1/00 , B24C1/08
CPC分类号： B24B31/003
摘要： A device for finishing workpieces, such as automobile wheels. The device includes a bowl assembly containing polishing media therein, and a drive assembly including a rotatable turret which carries the wheels thereon so that same are orbitally driven through the polishing media. A cam arrangement is provided which essentially continuously adjusts the angle of the wheels relative to the polishing media by pivoting the wheels about respective vertical axes. The device is additionally provided with a vertical drive assembly which allows vertical oscillation of the wheels relative to the media, and the polishing device also permits adjustment of the pitch or rake angle of the wheels relative to the horizontal.
摘要翻译：用于完成工件的装置，例如汽车轮。该装置包括其中包含抛光介质的碗组件，以及包括可转动的转台的驱动组件，所述可转动的转台在其上承载有轮子，以便轨道驱动通过抛光介质。提供了一种凸轮装置，其通过围绕相应的垂直轴线枢转来基本上连续地调节车轮相对于抛光介质的角度。该装置另外设置有垂直驱动组件，其允许车轮相对于介质的垂直振动，并且抛光装置还允许相对于水平面调整车轮的间距或前角。

7. 发明授权

US08645306B2 Automated calibration method and system for a diagnostic analyzer 有权
标题翻译：诊断分析仪的自动校准方法和系统
公开(公告)号：US08645306B2
公开(公告)日：2014-02-04
申请号：US12932192
申请日：2011-02-18
申请人： Jeremy Hammond
发明人： Jeremy Hammond
IPC分类号： G06F9/44
CPC分类号： G01N35/00693 , G01N2035/00702
摘要： A method to track stability and performance of diagnostic instrumentation, especially for veterinary automated hematology analyzers, applies a weighted moving averages algorithm to the diagnostic results of patient samples calculated by the analyzer. Control chart rules are used to set limits or ranges in order to determine if weighted averaged diagnostic results are within or outside of such limits or ranges. If the weighted average diagnostic results are outside of such control chart rule limits, then fuzzy logic and a gradient descent algorithm are applied to the weighted averaged diagnostic results.
摘要翻译：用于跟踪诊断仪器的稳定性和性能的方法，特别是对于兽医自动血液分析仪，可以将加权移动平均值算法应用于由分析仪计算的患者样本的诊断结果。控制图规则用于设置限制或范围，以确定加权平均诊断结果是否在这些限制或范围之内或之外。如果加权平均诊断结果超出这种控制图规则限制，则将模糊逻辑和梯度下降算法应用于加权平均诊断结果。

8. 发明授权

US06435007B1 Materials breakthrough monitoring sensor system 失效
标题翻译：材料突破监控传感器系统
公开(公告)号：US06435007B1
公开(公告)日：2002-08-20
申请号：US09560578
申请日：2000-04-27
申请人： Dean Smith , Todd Mlsna , Jeremy Hammond
发明人： Dean Smith , Todd Mlsna , Jeremy Hammond
IPC分类号： G01N1508
CPC分类号： G01N29/022 , G01N7/10 , G01N2291/0256 , G01N2291/02872 , G01N2291/0423 , G01N2291/106
摘要： A sensor system that monitors agent breakthrough through a vapor barrier and related test process. The system includes a substantially airtight test chamber for retaining the vapor barrier, which may be formed of one or more layers of one or more materials. A sensor element array placed adjacent to the barrier under test includes elements that are sensitive to one or more agents of interest and elements that are insensitive to such agents. The insensitive elements provide a baseline reference signal that is compared to the output signal of the sensitive elements. As the agent contacts the array, the electrical signal output from the sensitive elements changes in comparison to that of the reference elements. The sensor array is sensitive enough to detect low levels of the agent when the agent passes through the barrier. A control system is used to regulate and monitor environmental conditions within the chamber and to process electrical signals from the sensor array.
摘要翻译：一种传感器系统，通过蒸汽屏障和相关测试过程来监控代理人的突破。该系统包括用于保持蒸气阻挡物的基本上气密的测试室，其可以由一个或多个一个或多个材料层形成。放置在与被测屏障相邻的传感器元件阵列包括对感兴趣的一个或多个感兴趣的元件敏感的元件和对这种试剂不敏感的元件。不敏感元件提供与敏感元件的输出信号相比较的基准参考信号。当代理人接触阵列时，从敏感元件输出的电信号与参考元件相比变化。传感器阵列足够敏感，以便在试剂穿过屏障时检测试剂的低含量。控制系统用于调节和监测室内的环境条件并处理来自传感器阵列的电信号。

9. 发明申请

US20130006566A1 Automated Calibration Method and System for a Diagnostic Analyzer 有权
标题翻译：诊断分析仪的自动校准方法和系统
公开(公告)号：US20130006566A1
公开(公告)日：2013-01-03
申请号：US13548769
申请日：2012-07-13
申请人： Jeremy Hammond , Dominic Pelletier , Jason Aguiar
发明人： Jeremy Hammond , Dominic Pelletier , Jason Aguiar
IPC分类号： G06F19/00
CPC分类号： G01N35/00693 , G01N2035/00702
摘要： An automated method for calibrating in real time a diagnostic analyzer includes the steps of receiving diagnostic results of patient samples calculated by the analyzer using pre-set parameters of the analyzer, and calculating the centroid of the analyzer's diagnostic results. The centroid of the analyzer's diagnostic results is subtracted from a centroid of diagnostic results of a field population of comparable analyzers to obtain a bias in the centroid of the analyzer's diagnostic results. The bias is compared to predetermined limits Should the bias fall outside the predetermined limits, an optimization factor is derived and applied to the analyzer's diagnostic results to obtain optimized results from the analyzer without changing the pre-set parameters of the analyzer.
摘要翻译：用于实时校准诊断分析仪的自动化方法包括以下步骤：使用分析仪的预设参数来接收由分析仪计算的患者样品的诊断结果，以及计算分析仪诊断结果的质心。分析仪诊断结果的重心从相当分析仪的现场人群的诊断结果的重心中减去，以获得分析仪诊断结果的质心偏差。将偏压与预定限度进行比较如果偏差超出预定极限，则推导出优化因子并将其应用于分析仪的诊断结果，以从分析仪获得优化结果，而无需更改分析仪的预设参数。

10. 发明申请

US20080131326A1 Pipette tip 有权
标题翻译：移液器吸头
公开(公告)号：US20080131326A1
公开(公告)日：2008-06-05
申请号：US11985439
申请日：2007-11-15
申请人： Dominic Pelletier , Jeffrey Phelps , Jason Aguiar , Jeremy Hammond , William J. Traigle , Chandler G. Sinnett
发明人： Dominic Pelletier , Jeffrey Phelps , Jason Aguiar , Jeremy Hammond , William J. Traigle , Chandler G. Sinnett
IPC分类号： B01L3/02
CPC分类号： B01L3/0275 , B01L3/0262 , B01L2200/141 , B01L2400/025
摘要： A pipette tip includes a main body having an upper end, a lower end and a sidewall extending between the two ends. A bore extends axially through the main body between the upper and lower ends. The lower end has a bottom surface in which is formed a central opening that communicates with the axial bore to allow the passage of fluid therethrough. The bottom surface is formed with at least one groove that may be concentrically disposed or spirally disposed about the central opening. The at least one groove acts to inhibit fluid passing through the central opening from at least partially flowing along the outer surface of the sidewall from the central opening toward the upper end of the main body of the pipette tip.
摘要翻译：移液管尖端包括具有上端，下端和在两端之间延伸的侧壁的主体。孔在上端和下端之间轴向延伸通过主体。下端具有底表面，其中形成有与轴向孔连通以允许流体通过的中心开口。底表面形成有至少一个凹槽，其可以围绕中心开口同心地设置或螺旋地设置。所述至少一个凹槽用于阻止流经中心开口的流体至少部分地沿着侧壁的外表面从中心开口朝向移液管尖端主体的上端流动。

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