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1. 发明授权

US09020597B2 Device and implantation system for electrical stimulation of biological systems 有权
标题翻译：用于电刺激生物系统的装置和植入系统
公开(公告)号：US09020597B2
公开(公告)日：2015-04-28
申请号：US13463803
申请日：2012-05-03
申请人： Virender K. Sharma , Edy Sofer , Paul V. Goode , Bevil Hogg , Shai Policker , Matthew Joseph Gani , Jay Miazga , Kaila Raby
发明人： Virender K. Sharma , Edy Sofer , Paul V. Goode , Bevil Hogg , Shai Policker , Matthew Joseph Gani , Jay Miazga , Kaila Raby
IPC分类号： A61N1/36 , A61B5/11 , A61B5/00 , A61B5/053
CPC分类号： A61N1/36007 , A61B5/0538 , A61B5/1116 , A61B5/4836 , A61N1/0517 , A61N1/3606 , A61N1/36139 , A61N1/3614 , A61N1/36171 , A61N1/36175 , A61N1/36178
摘要： The present specification discloses devices and methodologies for the treatment of GERD. Individuals with GERD may be treated by implanting a stimulation device within the patient's lower esophageal sphincter and applying electrical stimulation to the patient's lower esophageal sphincter, in accordance with certain predefined protocols. The presently disclosed devices have a simplified design because they do not require sensing systems capable of sensing when a person is engaged in a wet swallow, have improved energy storage requirements, enable improved LES function while concurrently delivering additional health benefits, and enable improved LES function post stimulation termination.
摘要翻译：本说明书公开了用于治疗GERD的装置和方法。具有GERD的个体可以通过在患者的下食管括约肌内植入刺激装置并根据某些预定义的方案对患者的下食管括约肌施加电刺激来治疗。目前公开的设备具有简化的设计，因为它们不需要能够感测人从事湿吞咽的感测系统，具有改善的能量储存要求，能够改善LES功能，同时提供额外的健康益处，并且能够改善LES功能后刺激终止。

2. 发明申请

US20120110844A1 METHODS AND SYSTEMS FOR SECURING ELECTRODE LEADS 审中-公开
标题翻译：用于保护电极引线的方法和系统
公开(公告)号：US20120110844A1
公开(公告)日：2012-05-10
申请号：US13354501
申请日：2012-01-20
申请人： Corinne H. Johnson , Jay Miazga
发明人： Corinne H. Johnson , Jay Miazga
IPC分类号： H01R43/048
CPC分类号： A61N1/048 , A61N1/0476 , A61N1/05 , Y10T29/49185
摘要： Methods and systems for securing electrode leads are disclosed. An electrode system in accordance with one embodiment includes an electrode contact, a connector attached to the electrode contact, and an electrical lead. The electrical lead can be received in an opening of the contact, with an inner surface of the opening applying a generally uniform radial pressure around a circumference of the electrical lead. For example, the contact can have a tubular shape, optionally with an elongated slit, and can be crimped around the lead to apply the generally uniform radial pressure.
摘要翻译：公开了用于固定电极引线的方法和系统。根据一个实施例的电极系统包括电极接触件，连接到电极接触件的连接器和电引线。电引线可以容纳在触点的开口中，开口的内表面围绕电引线的圆周施加大致均匀的径向压力。例如，接触件可以具有管状形状，可选地具有细长狭缝，并且可以卷绕在引线周围以施加大致均匀的径向压力。

3. 发明申请

US20110295335A1 DEVICE AND IMPLANTATION SYSTEM FOR ELECTRICAL STIMULATION OF BIOLOGICAL SYSTEMS 有权
标题翻译：用于生物系统电刺激的装置和植入系统
公开(公告)号：US20110295335A1
公开(公告)日：2011-12-01
申请号：US13041098
申请日：2011-03-04
申请人： Virender K. SHARMA , Matthew Joseph Gani , Paul V. Goode , Bevil Hogg , Jay Miazga , Shai Policker , Kaila Raby
发明人： Virender K. SHARMA , Matthew Joseph Gani , Paul V. Goode , Bevil Hogg , Jay Miazga , Shai Policker , Kaila Raby
IPC分类号： A61N1/36
CPC分类号： A61B5/0031 , A61B5/037 , A61B5/0538 , A61B5/1116 , A61B5/14539 , A61B5/4211 , A61B5/4836 , A61N1/36007 , A61N1/3606 , A61N1/36139 , A61N1/36157 , A61N1/36171 , A61N1/36175 , A61N1/37235
摘要： The present specification discloses devices and methodologies for the treatment of nocturnal GERD. Individuals with nocturnal GERD may be treated by implanting a stimulation device within the patient's lower esophageal sphincter and applying electrical stimulation to the patient's lower esophageal sphincter, in accordance with certain predefined protocols. The presently disclosed devices have a simplified design because they do not require sensing systems capable of sensing when a person is engaged in a wet swallow and have improved energy storage requirements.
摘要翻译：本说明书公开了用于治疗夜间GERD的装置和方法。具有夜间GERD的个体可以通过在患者的下食管括约肌内植入刺激装置并根据某些预定义的方案对患者的下食道括约肌施加电刺激来治疗。目前公开的设备具有简化的设计，因为它们不需要能够感测人何时从事湿式吞咽并具有改进的能量存储要求的感测系统。

4. 发明授权

US06135001A Strip cutter for adhesive-backed media 有权
标题翻译：胶带支撑介质剥线刀
公开(公告)号：US06135001A
公开(公告)日：2000-10-24
申请号：US162932
申请日：1998-09-29
申请人： Jay Miazga , Pixie Ann Austin , Duane M. Fox
发明人： Jay Miazga , Pixie Ann Austin , Duane M. Fox
IPC分类号： B26D1/18 , B26D1/20 , B26D1/22 , B26D3/08 , B26D5/02 , B26D7/08 , B26D7/20 , B26D7/26 , B26D14/00
CPC分类号： B26D7/2621 , B26D1/185 , B26D1/205 , B26D1/225 , B26D3/085 , B26D5/02 , B26D7/088 , B26D7/20 , B26D7/2614 , B41J11/703 , Y10T83/2213 , Y10T83/7863 , Y10T83/7872 , Y10T83/8822
摘要： This is a cutter assembly for linerless strip media having an uncovered adhesive backing. There is a cutter for transverse movement across the media and a backing bar with at least two cutting edges. The backing bar can be rotated to place one of the cutting edges in contact with the cutter. A cleaning station cleans the previously used cutting edge as the bar is rotated. Rotating and fixed cutters can be used. The cutter is replaceable and can be supplied in combination with as associated media for which it is designed. The cutter may partially cut the media to make it separate without fouling the cutter with adhesive. A self-healing "solid" roller is also disclosed.
摘要翻译：这是一种用于无衬纸条介质的切割器组件，其具有未覆盖的粘合剂背衬。有一个用于跨介质的横向运动的切割器和具有至少两个切削刃的支撑杆。支撑杆可以旋转以将其中一个切割刃与切割器接触。清洁工作台清洁先前使用的切割刃，因为杆旋转。可以使用旋转和固定切割器。刀具是可更换的，可以与其设计的相关介质一起提供。切割器可以部分地切割介质以使其分离，而不会使粘合剂污染切割器。还公开了一种自愈式“固体”辊。

5. 发明授权

US09079012B2 Methods for securing electrode leads 有权
标题翻译：用于固定电极引线的方法
公开(公告)号：US09079012B2
公开(公告)日：2015-07-14
申请号：US13354501
申请日：2012-01-20
申请人： Corinne H. Johnson , Jay Miazga
发明人： Corinne H. Johnson , Jay Miazga
IPC分类号： H01R43/00 , A61N1/04 , A61N1/05
CPC分类号： A61N1/048 , A61N1/0476 , A61N1/05 , Y10T29/49185
摘要： Methods for securing electrode leads are disclosed. An electrode system in accordance with one embodiment includes an electrode contact, a connector attached to the electrode contact, and an electrical lead. The electrical lead can be received in an opening of the contact, with an inner surface of the opening applying a generally uniform radial pressure around a circumference of the electrical lead. For example, the contact can have a tubular shape, optionally with an elongated slit, and can be crimped around the lead to apply the generally uniform radial pressure.
摘要翻译：公开了用于固定电极引线的方法。根据一个实施例的电极系统包括电极接触件，连接到电极接触件的连接器和电引线。电引线可以容纳在触点的开口中，开口的内表面围绕电引线的圆周施加大致均匀的径向压力。例如，接触件可以具有管状形状，可选地具有细长狭缝，并且可以卷绕在引线周围以施加大致均匀的径向压力。

6. 发明授权

US08126529B2 Methods and systems for securing electrode leads 有权
标题翻译：用于固定电极引线的方法和系统
公开(公告)号：US08126529B2
公开(公告)日：2012-02-28
申请号：US11858810
申请日：2007-09-20
申请人： Corinne H. Johnson , Jay Miazga
发明人： Corinne H. Johnson , Jay Miazga
IPC分类号： A61B5/04
CPC分类号： A61N1/048 , A61N1/0476 , A61N1/05 , Y10T29/49185
摘要： Methods and systems for securing electrode leads are disclosed. An electrode system in accordance with one embodiment includes an electrode contact, a connector attached to the electrode contact, and an electrical lead. The electrical lead can be received in an opening of the contact, with an inner surface of the opening applying a generally uniform radial pressure around a circumference of the electrical lead. For example, the contact can have a tubular shape, optionally with an elongated slit, and can be crimped around the lead to apply the generally uniform radial pressure.
摘要翻译：公开了用于固定电极引线的方法和系统。根据一个实施例的电极系统包括电极接触件，连接到电极接触件的连接器和电引线。电引线可以容纳在触点的开口中，开口的内表面围绕电引线的圆周施加大致均匀的径向压力。例如，接触件可以具有管状形状，可选地具有细长狭缝，并且可以卷绕在引线周围以施加大致均匀的径向压力。

7. 发明申请

US20110307027A1 DEVICE AND IMPLANTATION SYSTEM FOR ELECTRICAL STIMULATION OF BIOLOGICAL SYSTEMS 有权
标题翻译：用于生物系统电刺激的装置和植入系统
公开(公告)号：US20110307027A1
公开(公告)日：2011-12-15
申请号：US13041063
申请日：2011-03-04
申请人： Virender K. SHARMA , Matthew Joseph GANI , Paul V. GOODE , Bevil HOGG , Jay MIAZGA , Shai POLICKER , Kaila RABY
发明人： Virender K. SHARMA , Matthew Joseph GANI , Paul V. GOODE , Bevil HOGG , Jay MIAZGA , Shai POLICKER , Kaila RABY
IPC分类号： A61N1/18
CPC分类号： A61B5/0031 , A61B5/037 , A61B5/0538 , A61B5/1116 , A61B5/14539 , A61B5/4211 , A61B5/4836 , A61N1/36007 , A61N1/3606 , A61N1/36139 , A61N1/36157 , A61N1/36171 , A61N1/36175 , A61N1/37235
摘要： The present specification discloses devices and methodologies for the treatment of GERD. Individuals with GERD may be treated by implanting a stimulation device within the patient's lower esophageal sphincter and applying electrical stimulation to the patient's lower esophageal sphincter, in accordance with certain predefined protocols. The presently disclosed devices have a simplified design because they do not require sensing systems capable of sensing when a person is engaged in a wet swallow and have improved energy storage requirements.
摘要翻译：本说明书公开了用于治疗GERD的装置和方法。具有GERD的个体可以通过在患者的下食管括约肌内植入刺激装置并根据某些预定义的方案对患者的下食管括约肌施加电刺激来治疗。目前公开的设备具有简化的设计，因为它们不需要能够感测人何时从事湿式吞咽并具有改进的能量存储要求的感测系统。

8. 发明申请

US20090124848A1 Receptacles for Implanted Device Control Magnets, and Associated Systems and Methods 审中-公开
标题翻译：注入装置控制磁体的插座，以及相关系统和方法
公开(公告)号：US20090124848A1
公开(公告)日：2009-05-14
申请号：US12133903
申请日：2008-06-05
申请人： Jay Miazga
发明人： Jay Miazga
IPC分类号： A61N2/00
CPC分类号： A61N1/08
摘要： Receptacles for implanted device control magnets, and associated systems and methods are disclosed. A system in accordance with one embodiment includes a magnet receptacle that in turn has a first portion with a first magnetically conductive material and a second portion with a second magnetically conductive material. At least one of the first and second portions can be moveable relative to the other between a closed configuration and an open configuration, with the first and second portions forming a cavity when in the closed configuration, and with the first magnetically conductive material proximate to a first side of the cavity and the second magnetically conductive material proximate to a second side of the cavity facing toward the first side.
摘要翻译：公开了用于植入装置控制磁体的插座以及相关联的系统和方法。根据一个实施例的系统包括磁体插座，磁体插座又具有带有第一导电材料的第一部分和具有第二导电材料的第二部分。第一和第二部分中的至少一个可以在闭合构型和开放构型之间相对于另一个部分移动，当处于闭合构型时，第一和第二部分形成空腔，并且第一导电材料接近于所述腔的第一侧和靠近所述空腔的朝向所述第一侧的第二侧的所述第二导磁材料。

9. 发明授权

US07308318B2 Percutaneous apparatus with electrical coupling 失效
标题翻译：具有电耦合的经皮装置
公开(公告)号：US07308318B2
公开(公告)日：2007-12-11
申请号：US10735807
申请日：2003-12-16
申请人： Jay Miazga , Paul C. Leonard , Chris Genau
发明人： Jay Miazga , Paul C. Leonard , Chris Genau
IPC分类号： A61N1/05
CPC分类号： A61N1/0551 , A61N1/05 , Y10S128/907
摘要： Methods and apparatuses for electrically coupling to percutaneous probes wherein entry angles of the percutaneous probes are controllable. An apparatus in accordance with one embodiment of the invention includes a percutaneous electrode having a first segment with a first sharp end and a second segment with a second end, at least part of the first segment being aligned along an axis and at least part of the second segment being offset from the axis. The apparatus can further include a coupling member having an aperture with a wall portion, at least a portion of which is electrically conductive. The apparatuses include shaped support surfaces, and associated methods wherein a non-planar support surface can more easily match a recipient's skin surface contour for improved comfort and security upon attachment.
摘要翻译：用于电耦合到经皮探针的方法和装置，其中经皮探针的入射角是可控的。根据本发明的一个实施例的装置包括经皮电极，其具有具有第一尖端的第一部分和具有第二端部的第二部分，所述第一部分的至少一部分沿轴线对准，并且至少部分第二段偏离轴。该装置还可以包括具有孔的耦合构件，该孔具有壁部分，其至少一部分是导电的。这些设备包括成形的支撑表面和相关联的方法，其中非平面支撑表面可以更容易地匹配受体的皮肤表面轮廓，以在附着时提高舒适性和安全性。

10. 发明申请

US20110295336A1 DEVICE AND IMPLANTATION SYSTEM FOR ELECTRICAL STIMULATION OF BIOLOGICAL SYSTEMS 有权
标题翻译：用于生物系统电刺激的装置和植入系统
公开(公告)号：US20110295336A1
公开(公告)日：2011-12-01
申请号：US13041116
申请日：2011-03-04
申请人： Virender K. SHARMA , Matthew Joseph Gani , Paul V. Goode , Bevil Hogg , Jay Miazga , Shai Policker , Kaila Raby
发明人： Virender K. SHARMA , Matthew Joseph Gani , Paul V. Goode , Bevil Hogg , Jay Miazga , Shai Policker , Kaila Raby
IPC分类号： A61N1/36
CPC分类号： A61B5/0031 , A61B5/037 , A61B5/0538 , A61B5/1116 , A61B5/14539 , A61B5/4211 , A61B5/4836 , A61N1/36007 , A61N1/3606 , A61N1/36139 , A61N1/36157 , A61N1/36171 , A61N1/36175 , A61N1/37235
摘要： The present specification discloses devices and methodologies for the treatment of diurnal GERD. Individuals with GERD may be treated by implanting a stimulation device within the patient's lower esophageal sphincter and applying electrical stimulation to the patient's lower esophageal sphincter, in accordance with certain predefined protocols. The presently disclosed devices have a simplified design because they do not require sensing systems capable of sensing when a person is engaged in a wet swallow and have improved energy storage requirements.
摘要翻译：本说明书公开了用于治疗昼夜GERD的装置和方法。具有GERD的个体可以通过在患者的下食管括约肌内植入刺激装置并根据某些预定义的方案对患者的下食管括约肌施加电刺激来治疗。目前公开的设备具有简化的设计，因为它们不需要能够感测人何时从事湿式吞咽并具有改进的能量存储要求的感测系统。

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