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1. 发明授权

US6107004A Method for making a tubular stent for use in medical applications 失效
标题翻译：制造用于医疗应用的管状支架的方法
公开(公告)号：US6107004A
公开(公告)日：2000-08-22
申请号：US49244
申请日：1998-03-27
申请人： James V. Donadio, III
发明人： James V. Donadio, III
IPC分类号： C23F1/02 , G03F9/00 , G03F7/22
CPC分类号： C23F1/02 , A61M2025/09066 , A61M2025/091 , A61M2025/09191
摘要： Manufacturing processes for apparatus, including slotted hypotube, for use as a catheter, a guidewire, a catheter sheath for use with catheter introducers or a drug infusion catheter/guidewire are disclosed. The manufacturing process includes creating a pattern of slots or apertures in a flexible metallic tubular member, by processes including but not limited to, electrostatic discharge machining (EDM), chemical milling, ablation and laser cutting. These slots or apertures may be cut completely or partially through the wall of the flexible metallic tubular member. These manufacturing processes may include the additional step of encasing the flexible metallic member such that a fluid tight seal is formed around the periphery of the tubular member.
摘要翻译：公开了用于装置的制造过程，包括用作导管的开槽海波管，导丝，用于导管导引器的导管护套或药物输注导管/导丝。制造过程包括通过包括但不限于静电放电加工（EDM），化学铣削，消融和激光切割的方法在柔性金属管状构件中形成槽或孔的图案。这些槽或孔可以完全或部分地穿过柔性金属管状构件的壁进行切割。这些制造方法可以包括包围柔性金属构件的附加步骤，使得围绕管状构件的周边形成流体密封。

2. 发明授权

US5911752A Method for collapsing a stent 失效
标题翻译：折叠支架的方法
公开(公告)号：US5911752A
公开(公告)日：1999-06-15
申请号：US710245
申请日：1996-09-13
申请人： Mark Owen Dustrude , James V. Donadio, III , J. Edward Shapland, II
发明人： Mark Owen Dustrude , James V. Donadio, III , J. Edward Shapland, II
IPC分类号： A61F2/06 , A61F2/84 , A61F2/90
CPC分类号： A61F2/91 , A61F2/915 , A61F2/958 , A61F2002/91558 , A61F2002/9522 , A61F2002/9583 , A61F2230/0054
摘要： A method for implanting a stent within a body passageway defined by a body wall. The method includes the step of fabricating the stent in an initial orientation in which the stent has an initial diameter and an initial length. The method also includes the step of collapsing the stent radially inward from the initial orientation to a collapsed orientation in which the stent has a collapsed length and a collapsed diameter. The stent is collapsed by deforming a portion of the stent beyond the elastic limit of the portion of the stent. The method further includes the step of positioning the collapsed stent at a desired location within the body passageway. Additionally, the method includes the step of expanding the stent radially outward from the collapsed orientation to a deployed orientation in which the stent has a deployed diameter and a deployed length. The deployed diameter and the deployed length are respectively substantially equal to the initial diameter and the initial length. The stent is expanding by deforming the portion of the stent beyond the elastic limit of the portion of the stent.
摘要翻译：一种用于将支架植入由身体壁限定的身体通路内的方法。该方法包括以支架具有初始直径和初始长度的初始取向制造支架的步骤。该方法还包括将支架从初始取向径向向内折叠到塌缩取向的步骤，其中支架具有塌缩长度和塌缩直径。支架通过将支架的一部分变形超过支架部分的弹性极限而折叠。该方法还包括将折叠的支架定位在身体通道内的期望位置的步骤。此外，该方法包括将支架从收缩方向径向向外扩张到其中支架具有展开直径和展开长度的展开方向的步骤。展开的直径和展开的长度分别基本上等于初始直径和初始长度。支架通过使支架的部分变形超过支架部分的弹性极限来扩张。

3. 发明授权

US5815904A Method for making a stent 失效
标题翻译：支架制作方法
公开(公告)号：US5815904A
公开(公告)日：1998-10-06
申请号：US816666
申请日：1997-03-13
申请人： Thomas L. Clubb , James V. Donadio, III , Mark O. Dustrude , J. Edward Shapland, II
发明人： Thomas L. Clubb , James V. Donadio, III , Mark O. Dustrude , J. Edward Shapland, II
IPC分类号： A61F2/00 , A61F2/06 , A61F2/90 , B23P17/00
CPC分类号： A61F2/91 , A61F2/915 , A61F2002/91541 , A61F2002/91558 , A61F2210/0076 , A61F2220/0058 , A61F2230/0013 , A61F2240/001 , Y10T29/49799 , Y10T29/49861
摘要： The present invention relates to a method for manufacturing a tubular medical device for insertion in a body. The method includes the step cutting a plurality of cross-sectional pieces or layers from a flat sheet. The pieces are cut so as to define inner apertures. The pieces are then aligned generally along an axis such that the pieces are arranged to form an elongated structure having an interior lumen extending longitudinally therethrough. Finally, the aligned pieces of the elongated structure are connected together such that each interconnected piece forms a layer of the tubular medical device.
摘要翻译：本发明涉及一种用于制造插入体内的管状医疗装置的方法。该方法包括从平板切割多个横截面的片或层的步骤。切割件以限定内部孔。然后将这些件大致沿着一个轴线对齐，使得这些件被布置成形成具有纵向穿过的内腔的细长结构。最后，细长结构的排列件连接在一起，使得每个相互接合的件形成管状医疗装置的一层。

4. 发明授权

US5741429A Flexible tubular device for use in medical applications 失效
标题翻译：用于医疗应用的柔性管状装置
公开(公告)号：US5741429A
公开(公告)日：1998-04-21
申请号：US455331
申请日：1995-05-31
申请人： James V. Donadio, III , David R. Holmes , Robert S. Schwartz , David Berry
发明人： James V. Donadio, III , David R. Holmes , Robert S. Schwartz , David Berry
IPC分类号： A61M25/00 , A61M25/06 , A61M25/16 , B29C41/20 , C23F1/02 , B44C1/22
CPC分类号： C23F1/02 , A61M25/0043 , A61M25/0054 , B29C41/20 , A61M2025/09066 , A61M2025/091 , A61M2025/09191 , A61M25/0662 , A61M25/09 , B29L2023/001 , B29L2031/7542
摘要： Manufacturing processes for apparatus, including slotted hypotube, for use as a catheter, a guidewire, a catheter sheath for use with catheter introducers or a drug infusion catheter/guidewire are disclosed. The manufacturing process includes creating a pattern of slots or apertures in a flexible metallic tubular member, by processes including but not limited to, electrostatic discharge machining (EDM), chemical milling, ablation and laser cutting. These slots or apertures may be cut completely or partially through the wall of the flexible metallic tubular member. These manufacturing processes may include the additional step of encasing the flexible metallic member such that a fluid tight seal is formed around the periphery of the tubular member.
摘要翻译：公开了用于装置的制造过程，包括用作导管的开槽海波管，导丝，用于导管导引器的导管护套或药物输注导管/导丝。制造过程包括通过包括但不限于静电放电加工（EDM），化学铣削，消融和激光切割的方法在柔性金属管状构件中形成槽或孔的图案。这些槽或孔可以完全或部分地穿过柔性金属管状构件的壁进行切割。这些制造方法可以包括包围柔性金属构件的附加步骤，使得围绕管状构件的周边形成流体密封。

5. 发明授权

US06203732B1 Method for manufacturing intraluminal device 失效
标题翻译：管腔内装置的制造方法
公开(公告)号：US06203732B1
公开(公告)日：2001-03-20
申请号：US09109554
申请日：1998-07-02
申请人： Elizabeth A. Clubb , Thomas L. Clubb , James V. Donadio, III
发明人： Elizabeth A. Clubb , Thomas L. Clubb , James V. Donadio, III
IPC分类号： B29C3342
CPC分类号： A61F2/915 , A61F2/91 , A61F2002/91533 , A61F2002/9155 , A61M25/0009 , A61M25/0013 , B29D23/001 , B29L2031/7542 , Y10S623/901
摘要： A generally tubular device (e.g., a stent or catheter) for placement in a lumen of a patient's body is made by forming a depressed pattern in an external surface of a mold. The depressed pattern corresponds to a desired shape of the generally tubular device. A material is deposited in the depressed pattern for the material to form the generally tubular device conforming to the depressed pattern. The generally tubular device is separated from the mold.
摘要翻译：用于放置在患者身体的内腔中的大体管状装置（例如，支架或导管）通过在模具的外表面中形成凹陷图案来制造。凹陷图案对应于通常管状装置的期望形状。材料沉积在用于材料的凹陷图案中以形成符合凹陷图案的大致管状装置。一般管状装置与模具分离。

6. 发明授权

US6027863A Method for manufacturing a tubular medical device 失效
标题翻译：管状医疗装置的制造方法
公开(公告)号：US6027863A
公开(公告)日：2000-02-22
申请号：US645607
申请日：1996-05-14
申请人： James V. Donadio, III
发明人： James V. Donadio, III
IPC分类号： A61M25/00 , A61M25/06 , A61M25/16 , B29C33/42 , B29C41/20 , B29C47/02 , C23F1/02 , G03F7/26
CPC分类号： A61M25/0013 , A61M25/0043 , A61M25/0054 , B29C33/42 , B29C41/20 , B29C47/023 , C23F1/02 , A61M2025/09066 , A61M2025/091 , A61M2025/09191 , A61M25/005 , A61M25/0051 , A61M25/0053 , A61M25/0138 , A61M25/0662 , A61M25/09 , B29C47/0023 , B29C47/0038 , B29L2023/001 , B29L2031/7542
摘要： Manufacturing processes for apparatus, including slotted hypotube, for use as a catheter, a guidewire, a catheter sheath for use with catheter introducers or a drug infusion catheter/guidewire are disclosed. The manufacturing process includes creating a pattern of slots or apertures in a flexible metallic tubular member, by processes including but not limited to, electrostatic discharge machining (EDM), chemical milling, ablation and laser cutting. These slots or apertures may be cut completely or partially through the wall of the flexible metallic tubular member. These manufacturing processes may include the additional step of encasing the flexible metallic member such that a fluid tight seal is formed around the periphery of the tubular member.
摘要翻译：公开了用于装置的制造过程，包括用作导管的开槽海波管，导丝，用于导管导引器的导管护套或药物输注导管/导丝。制造过程包括通过包括但不限于静电放电加工（EDM），化学铣削，消融和激光切割的方法在柔性金属管状构件中形成槽或孔的图案。这些槽或孔可以完全或部分地穿过柔性金属管状构件的壁进行切割。这些制造方法可以包括包围柔性金属构件的附加步骤，使得围绕管状构件的周边形成流体密封。

7. 发明授权

US5437288A Flexible catheter guidewire 失效
标题翻译：柔性导管导丝
公开(公告)号：US5437288A
公开(公告)日：1995-08-01
申请号：US940523
申请日：1992-09-04
申请人： Robert S. Schwartz , David Berry , Frederick S. Halverson , James V. Donadio, III
发明人： Robert S. Schwartz , David Berry , Frederick S. Halverson , James V. Donadio, III
IPC分类号： A61B5/00 , A61M25/09
CPC分类号： A61M25/09 , A61M2025/09075 , A61M2025/09133
摘要： An apparatus for use as a catheter guidewire and a method for making a catheter guidewire. The apparatus comprises an elongate non-coiled wire having a proximal portion, a distal tip and a flexible portion located between the proximal portion and the distal tip having axially spaced grooves cut therein. The method for making the guidewire includes burnishing one end of a wire to create a rounded distal tip and cutting a predetermined pattern of axially spaced grooves in a length of wire adjacent to the distal tip to create a flexible portion.
摘要翻译：用作导管导丝的装置和制造导管导丝的方法。该装置包括细长的非卷绕的线，其具有近端部分，远端部和位于近端部分和远端部之间的柔性部分，其中在其中切割有轴向间隔开的沟槽。用于制造导丝的方法包括抛光线的一端以产生圆形的远侧末端，并且切割与远侧末端相邻的线的长度方向上的轴向间隔开的凹槽的预定图案以形成柔性部分。

8. 发明授权

US4846186A Flexible guidewire 失效
标题翻译：柔性导丝
公开(公告)号：US4846186A
公开(公告)日：1989-07-11
申请号：US143008
申请日：1988-01-12
申请人： John W. Box , James V. Donadio
发明人： John W. Box , James V. Donadio
IPC分类号： A61B6/00
CPC分类号： A61M25/09 , A61M2025/09175
摘要： A guidewire suited for inserting both diagnostic and therapeutic catheters. The guidewire has an initial uniform diameter segment that is coated with Telfon along a majority of its length. This core station tapers along a uniform portion to a second constant diameter segment surrounded by a flexible spring tip. The core again tapers in a region where the flexible spring separates from the core. The core is then flattened to increase flexibility within the flexible spring and the flattened core and spring are brazed together at a extreme distal tip portion to form a hemispherical distal guidewire tip.
摘要翻译：适用于插入诊断和治疗导管的导丝。导丝具有初始均匀的直径段，其沿着其大部分长度涂覆有Telfon。该核心站沿着均匀部分逐渐变细至由柔性弹簧顶端围绕的第二恒定直径段。磁芯在柔性弹簧与磁芯分离的区域中再次变浅。然后将芯平展以增加柔性弹簧内的柔性，并且将扁平的芯和弹簧在最远端的尖端部分钎焊在一起以形成半球形的远端导丝尖端。

9. 发明授权

US5573520A Flexible tubular device for use in medical applications 失效
标题翻译：用于医疗应用的柔性管状装置
公开(公告)号：US5573520A
公开(公告)日：1996-11-12
申请号：US329691
申请日：1994-10-26
申请人： Robert S. Schwartz , David R. Holmes , Frederick S. Halverson , James V. Donadio, III , David Berry
发明人： Robert S. Schwartz , David R. Holmes , Frederick S. Halverson , James V. Donadio, III , David Berry
IPC分类号： A61M25/00 , A61M25/06 , B29C41/20 , B29C47/02 , C23F1/02
CPC分类号： A61M25/0013 , A61M25/0043 , B29C41/20 , B29C47/0023 , B29C47/023 , C23F1/02 , A61M2025/09066 , A61M2025/091 , A61M25/0051 , A61M25/0053 , A61M25/0054 , A61M25/0662 , A61M25/09 , B29C47/0026 , B29L2023/001 , B29L2031/7542
摘要： An apparatus for use as a catheter, a guidewire, a catheter sheath for use with catheter introducers or a drug infusion catheter/guidewire. The apparatus includes a flexible tubular member with an encasing covering the tubular member that creates a fluid-tight seal around the periphery of the tubular member. The tubular member is self-supporting and includes a plurality of apertures therein in a predetermined configuration to increase the flexibility of the tubular member.
摘要翻译：用作导管的装置，导丝，用于导管导引器或药物输注导管/导丝的导管护套。该装置包括柔性管状构件，其具有覆盖管状构件的封装，其围绕管状构件的周边产生流体密封的密封。管状构件是自支撑的并且在预定构造中包括多个孔，以增加管状构件的柔性。

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