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1. 发明申请

US20100063537A1 EMBOLIC PROTECTION SYSTEMS 有权
标题翻译：嵌入式保护系统
公开(公告)号：US20100063537A1
公开(公告)日：2010-03-11
申请号：US12621988
申请日：2009-11-19
申请人： Brooke Ren , James R. Lininger , Richard S. Kusleika
发明人： Brooke Ren , James R. Lininger , Richard S. Kusleika
IPC分类号： A61F2/01 , A61M29/00
CPC分类号： A61F2/013 , A61B2017/3484 , A61F2/958 , A61F2002/011 , A61F2002/016 , A61F2002/018 , A61F2002/061 , A61F2002/9583 , A61F2210/0014 , A61F2230/0006 , A61F2230/0067 , A61F2230/008 , A61F2250/0098 , A61M25/0032 , A61M25/1002
摘要： An embolic protection device comprising an expandable structure and a catheter. The catheter has a distal region and a working channel dimensioned to slideably receive an interventional device. The expandable structure is attached to the distal region of the catheter. The expandable structure has an expandable working channel extension and a working channel opening, the expandable working channel extension has a proximal end and a distal end, the proximal end of the working channel extension is attached to a distal end of the working channel, and the distal end of the working channel extension forms the working channel opening. The working channel opening is disposed proximate an exterior surface of the expandable structure when the expandable structure is expanded. The working channel, working channel extension, and the working channel opening form a continuous lumen.
摘要翻译：一种栓塞保护装置，包括可扩张结构和导管。导管具有远侧区域和工作通道，其尺寸适于可滑动地接收介入装置。可扩张结构附着到导管的远端区域。可膨胀结构具有可扩张的工作通道延伸部和工作通道开口，该可扩展工作通道延伸部具有近端和远端，工作通道延伸部的近端附接到工作通道的远端，并且工作通道延伸部分的远端形成工作通道开口。当可膨胀结构膨胀时，工作通道开口靠近可膨胀结构的外表面设置。工作通道，工作通道延伸和工作通道开口形成连续的流明。

2. 发明授权

US6159238A Stent having variable properties and method of its use 有权
公开(公告)号：US6159238A
公开(公告)日：2000-12-12
申请号：US314658
申请日：1999-05-19
申请人： Douglas P. Killion , James R. Lininger
发明人： Douglas P. Killion , James R. Lininger
IPC分类号： A61F2/00 , A61F2/91 , A61F2/915 , A61F2/06
CPC分类号： A61F2/915 , A61F2/91 , A61F2002/91525 , A61F2002/91533 , A61F2002/91558 , A61F2250/0018 , A61F2250/0029 , A61F2250/0039 , A61F2250/0048
摘要： A stent and method of its use, the stent in its expanded configuration, exhibiting varying outward radial force along its length. In use, the expanded stent is of a tapered configuration which provides greater force in vessel regions requiring greater force and less force in regions requiring less. In particular the stent is useful in the ostium regions and at areas of bifurcation in vessels. Varying force over the length of the stent is achieved by varying the number of elements, the density of elements, the thickness of the elements making up the stent body, and maintaining a substantially metal to artery ratio in the expanded stent over its length.

3. 发明授权

US07780719B2 Stent having variable properties and method of its use 有权
标题翻译：支架具有可变性质及其使用方法
公开(公告)号：US07780719B2
公开(公告)日：2010-08-24
申请号：US12177734
申请日：2008-07-22
申请人： Douglas P. Killion , James R. Lininger
发明人： Douglas P. Killion , James R. Lininger
IPC分类号： A61F2/06
CPC分类号： A61F2/915 , A61F2/91 , A61F2002/91525 , A61F2002/91533 , A61F2002/91558 , A61F2250/0018 , A61F2250/0029 , A61F2250/0039 , A61F2250/0048
摘要： A stent and method of its use, the stent in its expanded configuration, exhibiting varying outward radial force along its length. In use, the expanded stent is of a tapered configuration which provides greater force in vessel regions requiring greater force and less force in regions requiring less. In particular the stent is useful in the ostium regions and at areas of bifurcation in vessels. Varying force over the length of the stent is achieved by varying the number of elements, the density of elements, the thickness of the elements making up the stent body, and maintaining a substantially metal to artery ratio in the expanded stent over its length.
摘要翻译：支架及其使用方法，支架处于其扩张构型中，沿其长度呈现出不同的向外径向力。在使用中，扩张的支架是锥形构造，其在需要更小的区域中需要更大的力和更小的力的容器区域中提供更大的力。特别地，支架可用于口腔区域和血管中分叉区域。通过改变元件的数量，元件的密度，构成支架主体的元件的厚度，并且在其长度上保持扩张的支架中的基本上金属与动脉的比例来实现支架长度上的变化力。

4. 发明授权

US07402169B2 Stent having variable properties and method of its use 有权
标题翻译：支架具有可变性质及其使用方法
公开(公告)号：US07402169B2
公开(公告)日：2008-07-22
申请号：US11356750
申请日：2006-02-17
申请人： Douglas P. Killion , James R. Lininger
发明人： Douglas P. Killion , James R. Lininger
IPC分类号： A61F2/06
CPC分类号： A61F2/915 , A61F2/91 , A61F2002/91525 , A61F2002/91533 , A61F2002/91558 , A61F2250/0018 , A61F2250/0029 , A61F2250/0039 , A61F2250/0048
摘要： A stent and method of its use, the stent in its expanded configuration, exhibiting varying outward radial force along its length. In use, the expanded stent is of a tapered configuration which provides greater force in vessel regions requiring greater force and less force in regions requiring less. In particular the stent is useful in the ostium regions and at areas of bifurcation in vessels. Varying force over the length of the stent is achieved by varying the number of elements, the density of elements, the thickness of the elements making up the stent body, and maintaining a substantially metal to artery ratio in the expanded stent over its length.
摘要翻译：支架及其使用方法，支架处于其扩张构型中，沿其长度呈现出不同的向外径向力。在使用中，扩张的支架是锥形构造，其在需要更小的区域中需要更大的力和更小的力的容器区域中提供更大的力。特别地，支架可用于口腔区域和血管中分叉区域。通过改变元件的数量，元件的密度，构成支架主体的元件的厚度，并且在其长度上保持扩张的支架中的基本上金属与动脉的比例来实现支架长度上的变化力。

5. 发明授权

US5938697A Stent having variable properties 失效
标题翻译：支架具有可变属性
公开(公告)号：US5938697A
公开(公告)日：1999-08-17
申请号：US34249
申请日：1998-03-04
申请人： Douglas P. Killion , James R. Lininger
发明人： Douglas P. Killion , James R. Lininger
IPC分类号： A61F2/00 , A61F2/91 , A61F2/915 , A61F2/06 , A61F2/04
CPC分类号： A61F2/915 , A61F2/91 , A61F2002/91525 , A61F2002/91533 , A61F2002/91558 , A61F2250/0018 , A61F2250/0029 , A61F2250/0039 , A61F2250/0048
摘要： A stent and method of its use, the stent in its expanded configuration, exhibiting varying outward radial force along its length. In use, the expanded stent is of a tapered configuration which provides greater force in vessel regions requiring greater force and less force in regions requiring less. In particular the stent is useful in the ostium regions and at areas of bifurcation in vessels. Varying force over the length of the stent is achieved by varying the number of elements, the density of elements, the thickness of the elements making up the stent body, and maintaining a substantially metal to artery ratio in the expanded stent over its length.
摘要翻译：支架及其使用方法，支架处于其扩张构型中，沿其长度呈现出不同的向外径向力。在使用中，扩张的支架是锥形构造，其在需要更小的区域中需要更大的力和更小的力的容器区域中提供更大的力。特别地，支架可用于口腔区域和血管中分叉区域。通过改变元件的数量，元件的密度，构成支架主体的元件的厚度，并且在其长度上保持扩张的支架中的基本上金属与动脉的比例来实现支架长度上的变化力。

6. 发明授权

US08876853B2 Embolic protection systems 有权
标题翻译：栓塞保护系统
公开(公告)号：US08876853B2
公开(公告)日：2014-11-04
申请号：US12621988
申请日：2009-11-19
申请人： Brooke Ren , James R. Lininger , Richard S. Kusleika
发明人： Brooke Ren , James R. Lininger , Richard S. Kusleika
IPC分类号： A61F2/01 , A61M29/00 , A61M25/00 , A61B17/34 , A61F2/06 , A61M25/10
CPC分类号： A61F2/013 , A61B2017/3484 , A61F2/958 , A61F2002/011 , A61F2002/016 , A61F2002/018 , A61F2002/061 , A61F2002/9583 , A61F2210/0014 , A61F2230/0006 , A61F2230/0067 , A61F2230/008 , A61F2250/0098 , A61M25/0032 , A61M25/1002
摘要： An embolic protection device comprising an expandable structure and a catheter. The catheter has a distal region and a working channel. The working channel has a working channel opening disposed in the distal region of the catheter, the working channel and the working channel opening are dimensioned to slideably receive an interventional device. The working channel has a distal region and at least a portion of the distal region of the working channel is disposed within the expandable structure. The expandable structure, when expanded in a first blood vessel, is able to stop blood flow through a second blood vessel and able to allow blood to flow through the first blood vessel. The working channel opening is able to be disposed to allow an interventional device to enter the second blood vessel.
摘要翻译：一种栓塞保护装置，包括可扩张结构和导管。导管具有远侧区域和工作通道。工作通道具有设置在导管的远端区域中的工作通道开口，工作通道和工作通道开口的尺寸被设计成可滑动地接收介入装置。工作通道具有远侧区域，并且工作通道的远侧区域的至少一部分设置在可扩展结构内。当在第一血管中扩张时，可扩张结构能够阻止血液通过第二血管并且能够允许血液流过第一血管。工作通道开口能够被设置成允许介入装置进入第二血管。

7. 发明申请

US20080281397A1 STENT HAVING VARIABLE PROPERTIES AND METHOD OF ITS USE 有权
标题翻译：具有可变性质的特性及其使用方法
公开(公告)号：US20080281397A1
公开(公告)日：2008-11-13
申请号：US12177734
申请日：2008-07-22
申请人： Douglas P. Killion , James R. Lininger
发明人： Douglas P. Killion , James R. Lininger
IPC分类号： A61F2/82 , A61F2/84
CPC分类号： A61F2/915 , A61F2/91 , A61F2002/91525 , A61F2002/91533 , A61F2002/91558 , A61F2250/0018 , A61F2250/0029 , A61F2250/0039 , A61F2250/0048
摘要： A stent and method of its use, the stent in its expanded configuration, exhibiting varying outward radial force along its length. In use, the expanded stent is of a tapered configuration which provides greater force in vessel regions requiring greater force and less force in regions requiring less. In particular the stent is useful in the ostium regions and at areas of bifurcation in vessels. Varying force over the length of the stent is achieved by varying the number of elements, the density of elements, the thickness of the elements making up the stent body, and maintaining a substantially metal to artery ratio in the expanded stent over its length.
摘要翻译：支架及其使用方法，支架处于其扩张构型中，沿其长度呈现出不同的向外径向力。在使用中，扩张的支架是锥形构造，其在需要更小的区域中需要更大的力和更小的力的容器区域中提供更大的力。特别地，支架可用于口腔区域和血管中分叉区域。通过改变元件的数量，元件的密度，构成支架主体的元件的厚度，并且在其长度上保持扩张的支架中的基本上金属与动脉的比例来实现支架长度上的变化力。

8. 发明授权

US06939119B2 Method of reducing the wall thickness of a PTFE tube and product formed thereby 失效
标题翻译：减少由其形成的PTFE管和产品的壁厚的方法
公开(公告)号：US06939119B2
公开(公告)日：2005-09-06
申请号：US10668517
申请日：2003-09-23
申请人： Jason P. Hill , James R. Lininger , Brian J. Brown
发明人： Jason P. Hill , James R. Lininger , Brian J. Brown
IPC分类号： A61M25/00 , B29C43/22 , B29C47/20 , B29C55/18 , B29C55/24 , B29C67/00 , B29D23/00 , B29K27/18 , B29L23/00 , B29C55/22
CPC分类号： B29C67/0014 , B29C55/24
摘要： A thin wall PTFE tube is formed from an extruded green tube. The PTFE tube includes an inner tubular surface and an opposed outer tubular surface defining a tubular wall of a first thickness. The tubular wall is compressed to uniformly reduce the wall-thickness and circumferentially orient the tube. The PTFE tube is positioned over a first elongate roller with the inner tubular surface being in contact therewith. A second roller is positioned against the outer tubular surface of the PTFE tube. The pair of rollers are counter rotated so as to circumferentially compress the tubular wall between the rollers. This results in the uniform reduction in the tubular wall from the first thickness to a lesser second thickness and a circumferential orientation otherwise not occurring in an extruded PTFE paste extrusion.
摘要翻译：由挤出的绿色管形成薄壁PTFE管。 PTFE管包括内部管状表面和限定具有第一厚度的管状壁的相对的外部管状表面。管状壁被压缩以均匀地减小壁厚并且周向地定向管。 PTFE管定位在第一细长辊上，内管表面与其接触。第二辊定位在PTFE管的外管表面上。一对辊被反向旋转，以便周向地压缩辊之间的管状壁。这导致管状壁从第一厚度均匀地减小到较小的第二厚度，并且在挤出的PTFE浆料挤出中不发生圆周取向。

9. 发明授权

US06638468B1 Method of reducing the wall thickness of a PTFE tube 有权
标题翻译：降低PTFE管壁厚的方法
公开(公告)号：US06638468B1
公开(公告)日：2003-10-28
申请号：US09748417
申请日：2000-12-26
申请人： Jason P. Hill , James R. Lininger , Brian J. Brown
发明人： Jason P. Hill , James R. Lininger , Brian J. Brown
IPC分类号： B29B1110
CPC分类号： B29C67/0014 , B29C55/24
摘要： A thin wall PTFE tube is formed from an extruded green tube. The PTFE tube includes an inner tubular surface and an opposed outer tubular surface defining a tubular wall of a first thickness. The tubular wall is compressed to uniformly reduce the wall-thickness and circumferentially orient the tube. The PTFE tube is positioned over a first elongate roller with the inner tubular surface being in contact therewith. A second roller is positioned against the outer tubular surface of the PTFE tube. The pair of rollers are counter rotated so as to circumferentially compress the tubular wall between the rollers. This results in the uniform reduction in the tubular wall from the first thickness to a lesser second thickness and a circumferential orientation otherwise not occurring in an extruded PTFE paste extrusion.
摘要翻译：由挤出的绿色管形成薄壁PTFE管。 PTFE管包括内部管状表面和限定具有第一厚度的管状壁的相对的外部管状表面。管状壁被压缩以均匀地减小壁厚并且周向地定向管。 PTFE管定位在第一细长辊上，内管表面与其接触。第二辊定位在PTFE管的外管表面上。一对辊被反向旋转，以便周向地压缩辊之间的管状壁。这导致管状壁从第一厚度均匀地减小到较小的第二厚度，并且在挤出的PTFE浆料挤出中不发生圆周取向。

10. 发明授权

US07060091B2 Stent having variable properties and method of its use 失效
公开(公告)号：US07060091B2
公开(公告)日：2006-06-13
申请号：US10703642
申请日：2003-11-07
申请人： Douglas P. Killion , James R. Lininger
发明人： Douglas P. Killion , James R. Lininger
IPC分类号： A61F2/06
CPC分类号： A61F2/915 , A61F2/91 , A61F2002/91525 , A61F2002/91533 , A61F2002/91558 , A61F2250/0018 , A61F2250/0029 , A61F2250/0039 , A61F2250/0048
摘要： A stent and method of its use, the stent in its expanded configuration, exhibiting varying outward radial force along its length. In use, the expanded stent is of a tapered configuration which provides greater force in vessel regions requiring greater force and less force in regions requiring less. In particular the stent is useful in the ostium regions and at areas of bifurcation in vessels. Varying force over the length of the stent is achieved by varying the number of elements, the density of elements, the thickness of the elements making up the stent body, and maintaining a substantially metal to artery ratio in the expanded stent over its length.

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