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1. 发明授权

US07863038B2 Implantable biosensor from stratified nanostructured membranes 失效
标题翻译：来自分层纳米结构膜的可植入生物传感器
公开(公告)号：US07863038B2
公开(公告)日：2011-01-04
申请号：US10403845
申请日：2003-03-31
申请人： Massoud Motamedi , Nicholas A. Kotov , James P. Wicksted , Rinat Esenaliev
发明人： Massoud Motamedi , Nicholas A. Kotov , James P. Wicksted , Rinat Esenaliev
IPC分类号： C12M1/36
CPC分类号： A61B5/14532 , A61B5/1459 , C12Q1/006 , G01N33/54373
摘要： A new class of biosensors and methods for making and using same are disclosed. The biosensors are multi-layered membrane composites, where at least one layer is prepared by the layer-by-layer process and at least one layer is responsive to changes is a property of a biological system such as changes in the concentration of an atom, ion, molecule or molecular assembly. Because the biosensors are multi-layered, a single biosensor is capable monitor a number of different properties of a biological system simultaneously. The biosensors are monitored by systems that impinge an excitation waveform on the biosensors and analyze a reflected and/or a transmitted resultant waveform. Additionally, the biosensors can be associated with field activated electronic components so that implantable, self-contained analytical devices can be constructed and monitored by field generators, where data is transmitted to an analyzer after field activation.
摘要翻译：公开了一类新的生物传感器及其制造和使用方法。生物传感器是多层膜复合材料，其中至少一层通过逐层工艺制备，并且至少一层对变化有反应是生物系统的性质，例如原子浓度的变化，离子，分子或分子组装。由于生物传感器是多层次的，所以单个生物传感器能够同时监测生物系统的许多不同性质。通过在生物传感器上引发激发波形的系统监测生物传感器，并分析反射和/或发射的合成波形。此外，生物传感器可以与场激活的电子部件相关联，使得可以由现场发生器构建和监测可植入的，独立的分析装置，其中在场激活之后将数据传输到分析器。

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