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1. 发明授权

US10465724B2 Pistonless cylinder used for offshore pile gripper 有权
公开(公告)号：US10465724B2
公开(公告)日：2019-11-05
申请号：US16207180
申请日：2018-12-02
申请人： James J. Lee , William W. Lee
发明人： James J. Lee , William W. Lee
IPC分类号： F15B15/10 , F15B11/16 , E02D13/00
摘要： A simplified and improved pistonless cylinder based on an Aramid fiber reinforced elastomer tubular which is highly stiff in radial direction against radial expansion and elastic in axial extension, so as to form a completely sealed and extendable pressure chamber and to be able to perform as well as, or better than, most of the conventional hydraulic cylinders in terms of load bearing capacities, maximum stroke distances and service durability. This simplified cylinder employs no piston, piston rod, sealing seals or oil based hydraulic fluid, and utilizes non-metal materials to construct the majority of the parts for its extendable pressure chamber; therefore, this new cylinder can achieve significant weight and fabrication cost reduction. In addition, this new pistonless cylinder uses ordinary liquids, e.g., fresh water or seawater, as its hydraulic fluid, and can work directly as a hydraulic or pneumatic cylinder interchangeably without a need for much, if any, modification.

2. 发明申请

US20090214469A1 Methods and Compositions for the Treatment of Sepsis 审中-公开
标题翻译：脓毒症治疗方法和组成
公开(公告)号：US20090214469A1
公开(公告)日：2009-08-27
申请号：US12392673
申请日：2009-02-25
申请人： Jeffrey Gold , James J. Lee
发明人： Jeffrey Gold , James J. Lee
IPC分类号： A61K38/20
CPC分类号： A61K45/06 , A61K38/2033 , A61K2300/00
摘要： Methods for the treatment of sepsis are disclosed.
摘要翻译：公开了治疗败血症的方法。

3. 发明授权

US06427577B1 Load bearing apparatus for use with fluid power systems 失效
标题翻译：用于流体动力系统的承载装置
公开(公告)号：US06427577B1
公开(公告)日：2002-08-06
申请号：US09309084
申请日：1999-05-10
申请人： James J. Lee , Steven M. Byle , John C. Montague
发明人： James J. Lee , Steven M. Byle , John C. Montague
IPC分类号： F01B1900
CPC分类号： F16J3/06 , F15B15/103 , F16F13/00
摘要： A load bearing apparatus includes a first container having enclosed ends and at least one expansion segment. The expansion segment includes a first cylinder and a second cylinder of diameter smaller than the first cylinder disposed along a longitudinal axis of the first cylinder. An elastomer seal is connected between the first and second cylinders to form a fluid tight seal between the cylinders. The elastomer seal further permits translation of the first cylinder with respect to the second cylinder in a direction along the longitudinal axis of the first cylinder.
摘要翻译：承载装置包括具有封闭端和至少一个膨胀段的第一容器。膨胀段包括直径小于沿着第一气缸的纵向轴线设置的第一气缸的第一气缸和第二气缸。弹性体密封件连接在第一和第二气缸之间以在气缸之间形成流体密封。弹性体密封件还允许第一气缸相对于第二气缸在沿着第一气缸的纵向轴线的方向上平移。

4. 发明授权

US06215040B1 IL-5 transgenic mouse 有权
标题翻译： IL-5转基因小鼠
公开(公告)号：US06215040B1
公开(公告)日：2001-04-10
申请号：US09155884
申请日：1998-10-07
申请人： James J. Lee , Nancy A. Lee
发明人： James J. Lee , Nancy A. Lee
IPC分类号： C12N1500
CPC分类号： C12N15/8509 , A01K67/0275 , A01K2217/05 , A01K2227/105 , A01K2267/03 , A01K2267/0381 , C07K14/5409 , C12N2830/008
摘要： A transgenic mouse is provided, the cells of which contain and express IL-5 in a cell type- or tissue-specific manner and in an amount which results in an IL-5-associated pathology. Also provided are expression cassettes comprising an IL-5 gene, operably linked to a cell type- or tissue-specific transcriptional control sequence and methods of using transgenic mice comprising the expression cassettes
摘要翻译：提供了转基因小鼠，其细胞以细胞类型或组织特异性方式含有并表达IL-5，并以导致IL-5相关病理学的量表达。还提供了包含与细胞类型或组织特异性转录控制序列可操作地连接的IL-5基因的表达盒和使用包含表达盒的转基因小鼠的方法

5. 发明授权

US07048143B2 Container and cartridge for dispensing paper products 失效
标题翻译：用于分配纸制品的容器和墨盒
公开(公告)号：US07048143B2
公开(公告)日：2006-05-23
申请号：US10657621
申请日：2003-09-08
申请人： Richard Lee Sanders , James J. Lee
发明人： Richard Lee Sanders , James J. Lee
IPC分类号： A47K10/24
CPC分类号： A47K10/422
摘要： The present invention provides a container for dispensing individual paper products that includes a housing having side walls defining an interior area for receiving a plurality of paper products, wherein one of the side walls defines a slot. The housing further includes a means for urging paper products having a first portion external to the housing and a second portion extending through the slot into the interior area of the housing. The container may be included in a system for dispensing individual paper products that further includes a cartridge containing paper products within the container. The cartridge defines a dispensing opening and a second slot wherein the second portion of the means for urging paper products extends through the second slot into the interior area of the cartridge to contact the paper products and urge the paper products toward the dispensing opening.
摘要翻译：本发明提供了一种用于分配单个纸制品的容器，其包括具有限定用于容纳多个纸制品的内部区域的侧壁的壳体，其中一个侧壁限定狭槽。壳体还包括用于推动具有壳体外部的第一部分的纸制品的装置和延伸穿过狭槽进入壳体的内部区域的第二部分。容器可以包括在用于分配单独的纸制品的系统中，该系统进一步包括容纳容器内含有纸制品的盒。该盒限定了分配开口和第二槽，其中用于推动纸制品的装置的第二部分延伸穿过第二槽进入盒的内部区域以接触纸产品并将纸产品推向分配开口。

6. 发明授权

US06177610B1 Major basic protein deficient animals 失效
标题翻译：主要的基本蛋白质缺乏的动物
公开(公告)号：US06177610B1
公开(公告)日：2001-01-23
申请号：US09210017
申请日：1998-12-11
申请人： James J. Lee , Nancy A. Lee , Karen L. Denzler , Steven C. Farmer
发明人： James J. Lee , Nancy A. Lee , Karen L. Denzler , Steven C. Farmer
IPC分类号： C12N1511
CPC分类号： C12N15/8509 , A01K67/0276 , A01K2207/15 , A01K2217/00 , A01K2217/075 , A01K2227/105 , A01K2267/03 , A01K2267/0368 , C07K14/47
摘要： Major basic protein deficient non-human mammals that contain an inactivated major basic protein allele are described. A nucleic acid construct including an inactivated major basic protein gene is also described.
摘要翻译：描述了含有灭活的主要碱性蛋白等位基因的主要的基本蛋白质缺乏的非人哺乳动物。还描述了包含失活的主要碱性蛋白基因的核酸构建体。

7. 发明授权

US10145081B1 Pistonless cylinder used for offshore pile gripper 有权
公开(公告)号：US10145081B1
公开(公告)日：2018-12-04
申请号：US15846240
申请日：2017-12-19
申请人： James J. Lee , William W. Lee
发明人： James J. Lee , William W. Lee
IPC分类号： E02D27/52 , B66F3/24 , F15B15/10
摘要： This invention discloses a new type of force bearing cylinder which does not use any piston and its related parts for pushing/pulling its stroke. The pistonless cylinder uses ordinary liquids, e.g., fresh water or seawater, as its hydraulic fluid. The pistonless cylinder can work as a hydraulic or pneumatic cylinder interchangeably without a need for any modification, and is basically maintenance free during its service life. As one example of its applications, the disclosed pistonless cylinder can be used for deepwater pile grippers in offshore platform installation.

8. 发明申请

US20120079615A1 KNOCK-IN MICE WITH INDUCIBLE LOSS OF EOSINOPHILS 审中-公开
标题翻译：具有诱导性损伤的肌营养不良的小鼠
公开(公告)号：US20120079615A1
公开(公告)日：2012-03-29
申请号：US13240128
申请日：2011-09-22
申请人： James J. Lee , Nancy A. Lee
发明人： James J. Lee , Nancy A. Lee
IPC分类号： A01K67/027 , C12N5/10
CPC分类号： C07K14/485 , A01K67/0278 , A01K2217/072 , A01K2217/30 , A01K2227/105 , A01K2267/0368
摘要： Gene knock-in mice having a targeted insertion of the human diphtheria toxin receptor within the eosinophil peroxidase locus are described. Administering diphtheria toxin to such animals results in the loss of eosinophils in the animal. Accordingly, the knock-in mice and nucleic acid constructs featured in the document can be used to generate eosinophil-deficient transgenic animals that are useful for studying pathologies and treatments relating to tissues and organ systems that typically contain eosinophils.
摘要翻译：描述了在嗜酸性粒细胞过氧化物酶基因座内靶向插入人类白喉毒素受体的基因敲入小鼠。向这些动物施用白喉毒素导致动物嗜酸性粒细胞的丧失。因此，文献中特征的敲入小鼠和核酸构建体可用于产生嗜酸性粒细胞缺乏的转基因动物，其可用于研究与通常含有嗜酸性粒细胞的组织和器官系统有关的病理学和治疗。

9. 发明申请

US20190186506A1 PISTONLESS CYLINDER USED FOR OFFSHORE PILE GRIPPER 审中-公开
公开(公告)号：US20190186506A1
公开(公告)日：2019-06-20
申请号：US16207180
申请日：2018-12-02
申请人： James J. Lee , William W. Lee
发明人： James J. Lee , William W. Lee
IPC分类号： F15B15/10 , F15B11/16
CPC分类号： F15B15/10 , E02D13/00 , F15B11/16 , F15B2215/30
摘要： A simplified and improved pistonless cylinder based on an Aramid fiber reinforced elastomer tubular which is highly stiff in radial direction against radial expansion and elastic in axial extension, so as to form a completely sealed and extendable pressure chamber and to be able to perform as well as, or better than, most of the conventional hydraulic cylinders in terms of load bearing capacities, maximum stroke distances and service durability. This simplified cylinder employs no piston, piston rod, sealing seals or oil based hydraulic fluid, and utilizes non-metal materials to construct the majority of the parts for its extendable pressure chamber; therefore, this new cylinder can achieve significant weight and fabrication cost reduction. In addition, this new pistonless cylinder uses ordinary liquids, e.g., fresh water or seawater, as its hydraulic fluid, and can work directly as a hydraulic or pneumatic cylinder interchangeably without a need for much, if any, modification.

10. 发明授权

US6025539A IL-5 transgenic mouse 失效
标题翻译： IL-5转基因小鼠
公开(公告)号：US6025539A
公开(公告)日：2000-02-15
申请号：US629643
申请日：1996-04-09
申请人： James J. Lee , Nancy A. Lee
发明人： James J. Lee , Nancy A. Lee
IPC分类号： C12N15/09 , A01K67/027 , C07K14/54 , C12N15/85 , G01N33/15 , G01N33/566 , C12N5/00 , C12N15/00
CPC分类号： C12N15/8509 , A01K67/0275 , C07K14/5409 , A01K2217/05 , A01K2227/105 , A01K2267/03 , A01K2267/0381 , C12N2830/008
摘要： A transgenic mouse is provided, the cells of which contain and express IL-5 in a cell type- or tissue-specific manner and in an amount which results in an IL-5-associated pathology. Also provided are expression cassettes comprising an IL-5 gene, operably linked to a cell type- or tissue-specific transcriptional control sequence and methods of using transgenic mice comprising the expression cassettes.
摘要翻译：提供了转基因小鼠，其细胞以细胞类型或组织特异性方式含有并表达IL-5，并以导致IL-5相关病理学的量表达。还提供了包含与细胞类型或组织特异性转录控制序列可操作地连接的IL-5基因的表达盒和使用包含表达盒的转基因小鼠的方法。

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