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1. 发明授权

US4653498A Pulse oximeter monitor 失效
标题翻译：脉搏血氧仪监护仪
公开(公告)号：US4653498A
公开(公告)日：1987-03-31
申请号：US867005
申请日：1986-05-20
申请人： William New, Jr. , James E. Corenman
发明人： William New, Jr. , James E. Corenman
IPC分类号： A61B5/00 , A61B5/02
CPC分类号： A61B5/14551 , A61B2505/03
摘要： A display monitor is disclosed for a pulse oximeter of the type wherein light of two different wavelengths is passed through body tissue, such as a finger, an ear or the scalp, so as to be modulated by the pulsatile component of arterial blood therein and thereby indicate oxygen saturation. A tonal signal is emitted having a pitch proportional to the ratio of oxygen saturation and a sequential repetition proportional to pulse. A visual cue consisting of an array of strobed light emitting diodes is flashed having a total light output proportional to the magnitude of the pulse and a sequential flashing rate proportional to pulse rate. A systematic rejection of extraneous or irregular detected data prevents undue sounding of alarms.
摘要翻译：公开了一种用于脉冲血氧计的显示监视器，其中两种不同波长的光通过诸如手指，耳朵或头皮的身体组织，以便由其中的动脉血的脉动分量调节，从而表示氧饱和度。发出具有与氧饱和度的比例成比例的音调和与脉冲成比例的顺序重复的音调信号。闪烁了由阵列的选通发光二极管组成的视觉提示，其总光输出与脉冲的幅度成正比，顺序的闪烁速率与脉率成比例。系统地拒绝外部或不正确的检测数据可以防止警报的不适当的声音。

2. 发明授权

US4700708A Calibrated optical oximeter probe 失效
公开(公告)号：US4700708A
公开(公告)日：1987-10-20
申请号：US911978
申请日：1986-09-26
申请人： William New, Jr. , James E. Corenman
发明人： William New, Jr. , James E. Corenman
IPC分类号： A61B5/00 , G01N21/31
CPC分类号： A61B5/14552 , A61B5/1495 , G01N21/3151 , A61B2562/08
摘要： A probe apparatus for use with an optical oximeter is disclosed. A pair of light emitting diodes emit light of known narrow wavelengths through an appendage of a patient onto a photosensor. A resistor of coded known resistance is used to enable the oximeter to calculate the co-efficient of extinction of the wavelengths of the LEDs. The resistor, LEDs and photosensor are mounted on self-attaching hook and eye tape for mounting the probe onto the appendage of the patient. The probe is detachably wired to the oximeter, rendering the probe completely disposable. The oximeter is programmed at the factory to calculate the co-efficients of extinction of any LEDs which may be encountered in a series of disposable probes. From the co-efficients of extinction, the pulse rate and degree of arterial oxygen saturation is computed and displayed by the oximeter.

3. 发明授权

US4621643A Calibrated optical oximeter probe 失效
公开(公告)号：US4621643A
公开(公告)日：1986-11-11
申请号：US827478
申请日：1986-02-05
申请人： William New, Jr. , James E. Corenman
发明人： William New, Jr. , James E. Corenman
IPC分类号： A61B5/00 , G01N21/31
CPC分类号： A61B5/14552 , A61B5/1495 , G01N21/3151 , A61B2562/08
摘要： A probe apparatus for use with an optical oximeter is disclosed. A pair of light emitting diodes emit light of known narrow wavelengths through an appendage of a patient onto a photosensor. A resistor of coded known resistance is used to enable the oximeter to calculate the co-efficient of extinction of the wavelengths of the LEDs. The resistor, LEDs and photosensor are mounted on self-attaching hook and eye tape for mounting the probe onto the appendage of the patient. The probe is detachably wired to the oximeter, rendering the probe completely disposable. The oximeter is programmed at the factory to calculate the co-efficients of extinction of any LEDs which may be encountered in a series of disposable probes. From the co-efficients of extinction, the pulse rate and degree of arterial oxygen saturation is computed and displayed by the oximeter.

4. 发明授权

US4830014A Sensor having cutaneous conformance 失效
标题翻译：传感器具有皮肤一致性
公开(公告)号：US4830014A
公开(公告)日：1989-05-16
申请号：US70619
申请日：1987-07-07
申请人： David E. Goodman , James E. Corenman , William New, Jr. , Mark Yelderman
发明人： David E. Goodman , James E. Corenman , William New, Jr. , Mark Yelderman
IPC分类号： A61B5/00 , A61B5/024
CPC分类号： A61B5/6819 , A61B5/02427 , A61B5/14552 , A61B5/6826 , A61B5/6838
摘要： A sensor for trans-illumination of a blood perfused portion of flesh to measure light extinction during trans-illumination is disclosed. The sensor is preferably mounted on a fingertip but any digit or blood perfused portion of flesh will work. The sensor includes a first end for disposition on one side of the trans-illuminated flesh and a second end for disposition on the opposite and opposed side of the trans-illuminated flesh. A light source is mounted to the first side and a photo-sensor is mounted to the second side. If an elongated flexible strip is used, it is provided with adhesive and is suitably windowed that light is allowed to take an optical path through the finger. If no flexible strip is used, the two ends are aligned and secured to the flesh such that the light emitted takes an optical path through the finger. When the adhesive fastener is used, the effect of the light source and photo-detector substrates being integrated into the adhesive fastener is that they become, in effect, a part of the skin. The resulting device is resistant to accidental removal and avoids constriction of blood vessels. Most importantly, the low mass of the sensor itself and its conformance to, so as to effectively become a part of, the skin, prevents relative motion between the light source and sensor and the perfused flesh. This eliminates the common interference associated with the operation of conventional plethysmographs and oximeters.
摘要翻译：公开了一种用于反射照射血液灌注部分肉的传感器，以测量反照射期间的光消光。传感器优选地安装在指尖上，但任何数字或血液灌注部分的肉将起作用。传感器包括用于配置在反照照肉的一侧上的第一端和用于配置在反照照肉的相对侧上的第二端。光源安装到第一侧，并且光传感器安装到第二侧。如果使用细长的柔性条，则其具有粘合剂，并且适当地被窗口化，使得允许光穿过手指的光路。如果没有使用柔性条，则两端对准并固定在肉体上，使得所发出的光线穿过手指的光路。当使用粘合紧固件时，将光源和光检测器基底整合到粘合紧固件中的效果是它们实际上成为皮肤的一部分。所产生的装置能够防止意外移除并避免血管收缩。最重要的是，传感器本身的低质量及其与皮肤有效成为其一部分的一致性可防止光源和传感器与灌注液体之间的相对运动。这消除了与常规体积描记器和血氧计的操作相关的常见干扰。

5. 发明授权

US4802486A Method and apparatus for detecting optical pulses 失效
标题翻译：用于检测光脉冲的方法和装置
公开(公告)号：US4802486A
公开(公告)日：1989-02-07
申请号：US742720
申请日：1985-06-07
申请人： David E. Goodman , James E. Corenman
发明人： David E. Goodman , James E. Corenman
IPC分类号： A61B5/00 , A61B5/024 , A61B5/0245 , A61B5/0428 , A61B5/02
CPC分类号： A61B5/14551 , A61B5/02416 , A61B5/0245 , A61B5/04282 , A61B5/7207
摘要： A method and apparatus for measuring and correlating a patient's heart activity with optical detection of the patient's blood flow. The method and apparatus permit more accurate determination of blood flow characteristics such as oxygen saturation and pulse rate. In a preferred embodiment, the heart activity is detected by monitoring the patient's EKG waveform, and the blood flow is detected by a non-invasive pulse oximeter. The occurrence of the R wave portion of the EKG signal is detected and the time delay by which an arterial pulse follows the R wave is determined to establish a time window in which an arterial is to be expected. The established time window provides the oximeter with a parameter enabling the oximeter to analyze the blood flow only when it is likely to present an arterial blood pulse for waveform analysis. The invention also includes adjusting the polarity of the detected EKG signal to have a preselected uniform upgoing or downgoing polarity.
摘要翻译：一种用于测量和关联患者的心脏活动与患者血流的光学检测的方法和装置。该方法和装置允许更精确地确定诸如氧饱和度和脉率之类的血流特性。在优选实施例中，通过监测患者的EKG波形来检测心脏活动，并且通过非侵入式脉搏血氧计检测血流量。检测到EKG信号的R波部分的出现，并且确定动脉脉冲跟随R波的时间延迟以建立其中预期动脉的时间窗口。建立的时间窗口为血氧计提供了一个参数，使血氧计仅在可能出现动脉血脉以进行波形分析时分析血流量。本发明还包括调整检测到的EKG信号的极性以具有预选的均匀上行或下行极性。

6. 再颁专利

USRE35122E Method and apparatus for detecting optical pulses 失效
公开(公告)号：USRE35122E
公开(公告)日：1995-12-19
申请号：US840437
申请日：1992-02-24
申请人： James E. Corenman , Robert T. Stone , Andras Boross , Deborah A. Briggs , David E. Goodman
发明人： James E. Corenman , Robert T. Stone , Andras Boross , Deborah A. Briggs , David E. Goodman
IPC分类号： A61B5/00
CPC分类号： A61B5/14551 , A61B5/7203 , A61B5/7207 , A61B5/7257
摘要： A method and apparatus for improving the calculation of oxygen saturation and other blood constituents by non-invasive pulse oximeters. The method and apparatus permit more accurate determination of blood flow by collecting time-measures of the absorption signal at two or more wavelengths and processing the collected time-measure to obtain composite pulsatile flow data from which artifacts have been filtered. The processing may occur in the time domain or in the frequency domain. In the preferred time domain embodiment, successive portions of periodic information are weighted and added together in synchrony to obtain the composite pulse information. In the preferred frequency domain embodiment, the time-measure is Fourier transformed into its spectral components to form the composite information. A new method and apparatus for correlating the heartbeat and optical pulse is provided whereby a product of the ECG R-wave and optical pulse signals corresponding to the same heartbeat is obtained, and one signal is time shifted relative to the other until a maximum waveform product corresponding to the heartbeat is determined.

7. 发明授权

US5129401A Method for distinguishing respiratory events in a gas analyzer 失效
标题翻译：用于区分气体分析仪中呼吸事件的方法
公开(公告)号：US5129401A
公开(公告)日：1992-07-14
申请号：US458974
申请日：1990-01-25
申请人： James E. Corenman , Daniel S. Goldberger , Edward M. Richards , Emil P. Rojas , James R. Braig , David A. Gallup
发明人： James E. Corenman , Daniel S. Goldberger , Edward M. Richards , Emil P. Rojas , James R. Braig , David A. Gallup
IPC分类号： A61B5/083 , G01N21/31 , G01N21/35
CPC分类号： A61B5/083 , G01N21/3504 , G01N2021/3129 , G01N2201/121
摘要： A gas analyzer system and method for detecting and displaying information of gases in a respiratory gas stream, comprising an optical bench including a gas pathway for the flow of a gas stream through the optical bench, a flow shaping inlet at the entrance to the optical bench's gas pathway, two infrared detection channel assemblies for measuring the partial pressures of the gases in the respiratory gas stream, a pressure sensor for measuring the pressure within the gas pathway, a temperature sensor for measuring the temperature within the optical bench, and a flow rate sensor for measuring the gas flow rate through the gas pathway, circuitry for processing the detected partial pressures of the gases and the measured values for pressure, temperature, and flow rate, and for providing output signals indicative of processed measured values, the detected partial pressures of the gasses, and characterization information with respect to the optical bench components; analog input circuitry for processing the signals output from the optical bench for input to analog processing circuitry; analog processing circuitry for processing and correcting at least the detected partial pressures of the gases signals for collision broadening, temperature, pressure in the gas pathway, barometric pressure, cross-correction, and characterization of the optical bench components, and providing output signals indicative of the corrected partial pressures of the gases to display processing circuitry; display processing circuitry for processing the signals for display of at least the corrected partial pressure of one gas on a cathode ray tube.
摘要翻译：一种用于检测和显示呼吸气流中的气体信息的气体分析仪系统和方法，包括一个光学台，包括用于通过光学台的气流流动的气体通道，在光学台的入口处的流动成形入口气体通道，用于测量呼吸气流中的气体的分压的两个红外检测通道组件，用于测量气体通道内的压力的压力传感器，用于测量光学平台内的温度的温度传感器，以及流速用于测量通过气体通路的气体流量的传感器，用于处理检测到的气体分压的电路和用于压力，温度和流速的测量值，以及用于提供指示经处理的测量值的输出信号，检测到的分压的气体，以及关于光学台架部件的表征信息; 模拟输入电路，用于处理从光学平台输出的用于输入到模拟处理电路的信号; 模拟处理电路，用于处理和校正至少检测到的气体信号的分压，用于碰撞扩张，气体通路中的温度，压力，气压，交叉校正和光学台部件的表征，以及提供指示校正的显示处理电路的气体分压; 显示处理电路，用于处理用于显示至少阴极射线管上的一种气体的校正分压的信号。

8. 发明授权

US4928692A Method and apparatus for detecting optical pulses 失效
标题翻译：用于检测光脉冲的方法和装置
公开(公告)号：US4928692A
公开(公告)日：1990-05-29
申请号：US275727
申请日：1988-11-23
申请人： David E. Goodman , James E. Corenman
发明人： David E. Goodman , James E. Corenman
IPC分类号： A61B5/00 , A61B5/024 , A61B5/0245 , A61B5/0428 , A61B5/02
CPC分类号： A61B5/14551 , A61B5/02416 , A61B5/0245 , A61B5/04282 , A61B5/7207
摘要： A method and apparatus for measuring and correlating a patient's heart activity with optical detection of the patient's blood flow. The method and apparatus permit more accurate determination of blood flow characteristics such as oxygen saturation and pulse rate. In a preferred embodiment, the heart activity is detected by monitoring the patient's EKG waveform, and the blood flow is detected by a non-invasive pulse oximeter. The occurrence of the R wave portion of the EKG signal is detected and the time delay by which an arterial pulse follows the R wave is determined to establish a time window in which an arterial is to be expected. The established time window provides the oximeter with a parameter enabling the oximeter to analyze the blood flow only when it is likely to present an arterial blood pulse for waveform analysis. The invention also includes adjusting the polarity of the detected EKG signal to have a preselected uniform upgoing or downgoing polarity.
摘要翻译：一种用于测量和关联患者的心脏活动与患者血流的光学检测的方法和装置。该方法和装置允许更精确地确定诸如氧饱和度和脉率之类的血流特性。在优选实施例中，通过监测患者的EKG波形来检测心脏活动，并且通过非侵入式脉搏血氧计检测血流量。检测到EKG信号的R波部分的出现，并且确定动脉脉冲跟随R波的时间延迟以建立其中预期动脉的时间窗口。建立的时间窗口为血氧计提供了一个参数，使血氧计仅在可能出现动脉血脉以进行波形分析时分析血流量。本发明还包括调整检测到的EKG信号的极性以具有预选的均匀上行或下行极性。

9. 发明授权

US4907166A Multichannel gas analyzer and method of use 失效
标题翻译：多通道气体分析仪及其使用方法
公开(公告)号：US4907166A
公开(公告)日：1990-03-06
申请号：US101931
申请日：1987-09-25
申请人： James E. Corenman , Daniel S. Goldberger , Edward M. Richards , Emil P. Rojas , James R. Braig , David A. Gallup
发明人： James E. Corenman , Daniel S. Goldberger , Edward M. Richards , Emil P. Rojas , James R. Braig , David A. Gallup
IPC分类号： A61B5/08 , A61B5/083 , G01N21/31 , G01N21/35 , G01N21/61 , G06F15/42
CPC分类号： A61B5/083 , G01N21/3504 , G01N2021/3129 , G01N21/61 , G01N2201/121
摘要： An improved gas analyzer system (FIG. 1) and method of use for detecting and displaying the partial pressures of certain constituent gases in a respiratory gas stream, the system comprising an optical bench (111) through which a respiratory gas flows and in which measurements of the gas are taken; analog input circuits (122) for receiving signals output from the optical bench (111) through which a respiratory gas flows and in which measurements of the gas are taken; analog processing circuits (124) for processing signals output from the analog input circuits (122); display processing circuits (128) for processing the signals output from the analog processing circuits (124) and other system circuitry; pixel logic circuits/analog outputs (130) for processing signals output from the display processing circuitry (128) and providing analog output ports; a five button panel (148), an alarm/knob board (144), and a speaker driver (152) for operator interface and activation of audible and visual alarms; a CRT driver for driving a CRT; and a power supply (158) for powering the system.

10. 发明授权

US5042522A Airway adapter with backflush tube 失效
标题翻译：气道适配器带反吹管
公开(公告)号：US5042522A
公开(公告)日：1991-08-27
申请号：US458971
申请日：1990-01-25
申请人： James E. Corenman , Daniel S. Goldberger , Edward M. Richards , Emil P. Rojas , James R. Braig , David A. Gallup
发明人： James E. Corenman , Daniel S. Goldberger , Edward M. Richards , Emil P. Rojas , James R. Braig , David A. Gallup
IPC分类号： A61B5/083 , G01N21/35
CPC分类号： G01N21/3504 , A61B5/083 , G01N2201/121 , Y10T137/4252 , Y10T137/8122
摘要： A backflushing system for an inlet filter in an airway adapter in a gas flow sampling and analyzing system includes a back flush fluid supply conduit and sampling conduit connected to the airway adapter by a single coupling element. Flow of back flush fluid causes material blocking the filter to be washed away into the respiratory conduit for disposal. Flow of backflush fluid is restricted to one way flow through the backflush conduit by a disk shaped valve member mounted in the air way adapter.
摘要翻译：用于气流采样和分析系统中的气道适配器中的入口过滤器的反冲洗系统包括背冲洗流体供应管道和通过单个联接元件连接到气道适配器的取样管道。反冲洗液的流动导致材料阻塞过滤器被冲走到呼吸管道中进行处置。反冲洗流体的流动被限制为通过安装在空气调节适配器中的盘形阀构件通过反冲洗管道的单向流动。

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