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1. 发明授权

US06575527B1 Vehicle headliner assembly and method of installation 失效
标题翻译：车顶装配及安装方法
公开(公告)号：US06575527B1
公开(公告)日：2003-06-10
申请号：US09775212
申请日：2001-02-01
申请人： James E. Bishop, Jr.
发明人： James E. Bishop, Jr.
IPC分类号： B60R1302
CPC分类号： B60R13/0212 , B60R13/0275 , B60R13/0815
摘要： A semi-flexible vehicle headliner assembly and a method of installing the same are provided. The headliner assembly includes a headliner piece and a support unit. The headliner piece is bendable to permit variable shaping for installation. A method of installing the headliner assembly with an upper surface to the inside of a vehicle roof is provided which includes the steps of connecting a back side of a support unit to the inside of the vehicle roof and connecting the upper surface of the substrate to the roof of the vehicle temporarily until the substrate can be securely installed.
摘要翻译：提供了一种半柔性车顶用组件及其安装方法。顶篷组件包括顶篷件和支撑单元。顶篷片是可弯曲的，以允许可变形成安装。提供了一种将具有上表面的顶篷组件安装到车顶的方法，其包括以下步骤：将支撑单元的后侧连接到车顶的内部，并将基板的上表面连接到临时车顶，直至基片牢固地安装。

2. 发明授权

US6133429A Chromophores useful for the preparation of novel tandem conjugates 失效
标题翻译：用于制备新型串联共轭物的发色团
公开(公告)号：US6133429A
公开(公告)日：2000-10-17
申请号：US943491
申请日：1997-10-03
申请人： Kenneth A. Davis , James E. Bishop , Barnaby Abrams
发明人： Kenneth A. Davis , James E. Bishop , Barnaby Abrams
IPC分类号： G01N33/532 , G01N33/533 , G01N33/58 , C07K16/44
CPC分类号： G01N33/58 , G01N33/532 , G01N33/533 , Y10S436/80
摘要： The inventors herein disclose new heterobifunctional chromophores that are capable of coupling with two distinct moieties. One moiety may be either a signal-enhancing agent or a blocking agent. The second moiety may be one member of a specific binding pair. The invention is based in part on the surprising result that when a chromophore is used as a "cross-linker" between a signal-enhancing agent and a member of a binding pair (essentially being buried between the two), the signal of the chromophore is not quenched. This arrangement, wherein the chromophore acts simultaneously as a cross-linker and a detectable compound, provides significant advantages over previously known compounds since the chromophore is sterically hindered from interacting non-specifically with substances present in the test systems. Moreover, the chromophore can be used as a cross-linker with little or no loss of detectable signal.
摘要翻译：本发明人在此公开了能够与两个不同部分偶联的新的异双功能发色团。一个部分可以是信号增强剂或封闭剂。第二部分可以是特异性结合对的一个成员。本发明部分基于令人惊奇的结果，当发色团用作信号增强剂与结合对（基本上被埋在两者之间）的成员之间的“交联剂”时，发色团的信号没有淬火。这种布置，其中发色团作为交联剂和可检测化合物同时作用，提供了优于先前已知化合物的显着优点，因为发色团在空间上阻碍了非特异性地与测试系统中存在的物质相互作用。此外，发色团可以用作交联剂，几乎没有或没有可检测信号的损失。

3. 发明授权

US07076724B2 System and method for forward error correction 有权
公开(公告)号：US07076724B2
公开(公告)日：2006-07-11
申请号：US10348688
申请日：2003-01-22
申请人： Robert M. Cole , James E. Bishop
发明人： Robert M. Cole , James E. Bishop
IPC分类号： H03M13/00
CPC分类号： H04L1/0057 , G11B20/1833 , H03M13/31 , H03M13/35 , H04L25/4908
摘要： A system and method are provided for transferring a packet across a data link. The packet may include a stream of data symbols which is delimited by one or more framing symbols. Corruptions of the framing symbol which result in valid data symbols may be mapped to invalid symbols. If it is desired to transfer one of the valid data symbols that has been mapped to an invalid symbol, the data symbol may be replaced with an unused symbol. At the receiving end, these unused symbols are replaced with the corresponding valid data symbols. The data stream of the packet may be encoded with forward error correction information to detect and correct errors in the data stream.

4. 发明授权

US06897954B2 Instrument setup system for a fluorescence analyzer 有权
标题翻译：荧光分析仪仪器设置系统
公开(公告)号：US06897954B2
公开(公告)日：2005-05-24
申请号：US10326524
申请日：2002-12-20
申请人： James E. Bishop , Sunil S. Dalal , Zhenxiang Gong , Michael D. Lock
发明人： James E. Bishop , Sunil S. Dalal , Zhenxiang Gong , Michael D. Lock
IPC分类号： G01N15/14 , G01N21/64 , G01N21/78 , G01J3/30
CPC分类号： G01N21/6428 , G01N15/1459 , G01N2021/6441 , G01N2201/1241
摘要： The present invention provides instruments for analyzing a multiplicity of fluorescent dyes using a multiplicity of amplifying photodetectors, methods for using the instruments, methods for setting the instrument parameters, and methods for resetting the instrument parameters following a changed in photodetector amplification. The present invention is particularly applicable in the field of flow cytometry.
摘要翻译：本发明提供了使用多个放大光电检测器分析多种荧光染料的仪器，使用仪器的方法，用于设置仪器参数的方法以及在光电检测器放大变化之后复位仪器参数的方法。本发明特别适用于流式细胞仪领域。

5. 发明授权

US07296211B2 System and method for transferring data on a data link 失效
标题翻译：用于在数据链路上传输数据的系统和方法
公开(公告)号：US07296211B2
公开(公告)日：2007-11-13
申请号：US10348659
申请日：2003-01-22
申请人： Robert M. Cole , James E. Bishop
发明人： Robert M. Cole , James E. Bishop
IPC分类号： H03M13/00
CPC分类号： H04L1/0057 , G11B20/1833 , H03M13/31 , H03M13/35 , H04L25/4908
摘要： A system and method are provided for transferring a packet across a data link. The packet may include a stream of data symbols which is delimited by one or more framing symbols. Corruptions of the framing symbol which result in valid data symbols may be mapped to invalid symbols. If it is desired to transfer one of the valid data symbols that has been mapped to an invalid symbol, the data symbol may be replaced with an unused symbol. At the receiving end, these unused symbols are replaced with the corresponding valid data symbols. The data stream of the packet may be encoded with forward error correction information to detect and correct errors in the data stream.
摘要翻译：提供了一种通过数据链路传送数据包的系统和方法。分组可以包括由一个或多个成帧符号限定的数据符号流。导致有效数据符号的成帧符号的损坏可能被映射到无效符号。如果希望将已经映射的有效数据符号中的一个传送到无效符号，则可以用未使用的符号替换数据符号。在接收端，这些未使用的符号被替换为相应的有效数据符号。分组的数据流可以用前向纠错信息进行编码，以检测和纠正数据流中的错误。

6. 发明授权

US5620842A Determination of the number of fluorescent molecules on calibration beads for flow cytometry 失效
标题翻译：测定流式细胞仪校准珠上荧光分子的数量
公开(公告)号：US5620842A
公开(公告)日：1997-04-15
申请号：US413045
申请日：1995-03-29
申请人： Kenneth A. Davis , James E. Bishop
发明人： Kenneth A. Davis , James E. Bishop
IPC分类号： G01N15/10 , G01N15/14 , G01N33/58 , G01N33/96 , G01N31/00
CPC分类号： G01N15/1012 , G01N15/14 , G01N33/585 , G01N33/96 , Y10S435/967 , Y10S436/80 , Y10T436/101666
摘要： A rapid, simple method for preparing beads for calibrating flow cytometers which contain a known number of fluorophores per bead is presented. Briefly, the invention utilizes beads coated with a stable complex of a fluorophore and an enzyme. the enzymatic activity of a known number of beads gives an accurate measure of fluorophore density on those beads.
摘要翻译：提出了一种快速，简单的制备珠粒的方法，用于校准每个珠粒含有已知数量的荧光团的流式细胞仪。简言之，本发明利用涂覆有荧光团和酶的稳定复合物的珠粒。已知数量的珠的酶活性给出了这些珠上的荧光团密度的精确测量。

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