专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20050260665A1 Single label comparative hybridization 有权
标题翻译：单标记比较杂交
公开(公告)号：US20050260665A1
公开(公告)日：2005-11-24
申请号：US11134133
申请日：2005-05-19
申请人： Mansoor Mohammed , Natasa Dzidic , Christopher McCaskill , Jaeweon Kim
发明人： Mansoor Mohammed , Natasa Dzidic , Christopher McCaskill , Jaeweon Kim
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6837 , C12Q1/6823 , C12Q1/6825 , C12Q1/6841 , C12Q1/6883 , C12Q2600/16 , C12Q2565/501 , C12Q2539/101 , C12Q2537/155 , C12Q2545/107
摘要： The present invention provides methods of detecting and mapping chromosomal or genetic abnormalities associated with various diseases or with predisposition to various diseases, or to detecting the phenomena of large scale copy number variants. In particular, the present invention provides advanced methods of performing array-based comparative hybridization that allow reproducibility between samples and enhanced sensitivity by using the same detectable label for both test sample and reference sample nucleic acids. Invention methods are useful for the detection or diagnosis of particular disease conditions such as cancer, and detecting predisposition to cancer based on detection of chromosomal or genetic abnormalities and gene expression level. Invention methods are also useful for the detection or diagnosis of hereditary genetic disorders or predisposition thereto, especially in prenatal samples. Moreover, invention methods are also useful for the detection or diagnosis of de novo genetic aberrations associated with post-natal developmental abnormalities.
摘要翻译：本发明提供了检测和映射与各种疾病相关的染色体或遗传异常或具有各种疾病倾向的方法，或者检测大规模拷贝数变体的现象。特别地，本发明提供了进行基于阵列的比较杂交的先进方法，其通过使用相同的可检测标记用于测试样品和参照样品核酸，从而允许样品之间的再现性和增强的灵敏度。本发明方法可用于检测或诊断特定的疾病状况如癌症，并且基于染色体或遗传异常和基因表达水平的检测来检测癌症易感性。本发明的方法也可用于遗传性遗传疾病或其易感性的检测或诊断，特别是在产前样品中。此外，发明方法也可用于检测或诊断与产后发育异常相关的从头遗传畸变。

2. 发明授权

US08911942B2 Single label comparative hybridization 有权
标题翻译：单标记比较杂交
公开(公告)号：US08911942B2
公开(公告)日：2014-12-16
申请号：US11134133
申请日：2005-05-19
申请人： Mansoor S. Mohammed , Natasa Dzidic , Christopher McCaskill , Jaeweon Kim
发明人： Mansoor S. Mohammed , Natasa Dzidic , Christopher McCaskill , Jaeweon Kim
IPC分类号： C12Q1/68 , C07H21/02 , C07H21/04
CPC分类号： C12Q1/6837 , C12Q1/6823 , C12Q1/6825 , C12Q1/6841 , C12Q1/6883 , C12Q2600/16 , C12Q2565/501 , C12Q2539/101 , C12Q2537/155 , C12Q2545/107
摘要： The present invention provides methods of detecting and mapping chromosomal or genetic abnormalities associated with various diseases or with predisposition to various diseases, or to detecting the phenomena of large scale copy number variants. In particular, the present invention provides advanced methods of performing array-based comparative hybridization that allow reproducibility between samples and enhanced sensitivity by using the same detectable label for both test sample and reference sample nucleic acids. Invention methods are useful for the detection or diagnosis of particular disease conditions such as cancer, and detecting predisposition to cancer based on detection of chromosomal or genetic abnormalities and gene expression level. Invention methods are also useful for the detection or diagnosis of hereditary genetic disorders or predisposition thereto, especially in prenatal samples. Moreover, invention methods are also useful for the detection or diagnosis of de novo genetic aberrations associated with post-natal developmental abnormalities.
摘要翻译：本发明提供了检测和映射与各种疾病相关的染色体或遗传异常或具有各种疾病倾向的方法，或者检测大规模拷贝数变体的现象。特别地，本发明提供了进行基于阵列的比较杂交的先进方法，其通过使用相同的可检测标记用于测试样品和参照样品核酸，从而允许样品之间的再现性和增强的灵敏度。本发明方法可用于检测或诊断特定的疾病状况如癌症，并且基于染色体或遗传异常和基因表达水平的检测来检测癌症易感性。本发明的方法也可用于遗传性遗传疾病或其易感性的检测或诊断，特别是在产前样品中。此外，发明方法也可用于检测或诊断与产后发育异常相关的从头遗传畸变。

3. 发明申请

US20050249298A1 Multi-code multi-carrier code division multiple access (CDMA) system and method 审中-公开
标题翻译：多码多载波码分多址（CDMA）系统及方法
公开(公告)号：US20050249298A1
公开(公告)日：2005-11-10
申请号：US11118822
申请日：2005-04-28
申请人： Taeyoon Kim , Jaeweon Kim , Jeffrey Andrews , Theodore Rappaport
发明人： Taeyoon Kim , Jaeweon Kim , Jeffrey Andrews , Theodore Rappaport
IPC分类号： H04L5/02 , H04L27/28
CPC分类号： H04L5/026
摘要： A multi-code multicarrier CDMA system and method for communicating data by transforming a stream of data into a plurality of code sequences selected from a code book by associating symbols of the data stream with the code sequences of the code book, wherein the codebook includes M code sequences and each of the code sequences has a length of N data symbols, copying each of the code sequences onto one or more of a plurality of subcarriers, transmitting the plurality of subcarriers, receiving the plurality of transmitted subcarriers, demodulating the received subcarriers to result in the code sequences, transforming the code sequences back into the stream of data based upon the associations between the code sequences of the code book and the symbols of the data stream, changing at least one of the number M and lengths N of the code sequences in the code book.
摘要翻译：一种多码多载波CDMA系统和方法，用于通过将数据流的符号与码本的代码序列相关联，将数据流转换成从码本中选出的多个码序列来传送数据，其中码本包括M 代码序列和每个代码序列具有N个数据符号的长度，将每个代码序列复制到多个子载波中的一个或多个子载波上，发送多个子载波，接收多个发送的子载波，将接收的子载波解调为导致代码序列，基于代码簿的代码序列与数据流的符号之间的关联将代码序列转换回数据流，改变代码的数量M和长度N中的至少一个代码簿中的序列。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式