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1. 发明授权

US09147366B2 Method for driving a liquid crystal display device, an array substrate, method of manufacturing the array substrate and liquid crystal display device having the same 有权
标题翻译：液晶显示装置的驱动方法，阵列基板，阵列基板的制造方法以及具有该阵列基板的液晶显示装置
公开(公告)号：US09147366B2
公开(公告)日：2015-09-29
申请号：US12485721
申请日：2009-06-16
申请人： Yong-Seok Cho , Jae-Hyun Kim , Gee-Bum Kim , Jae-Hoon Hwang
发明人： Yong-Seok Cho , Jae-Hyun Kim , Gee-Bum Kim , Jae-Hoon Hwang
IPC分类号： G02F1/1362 , G02F1/1368 , G02F1/1335 , G09G3/36
CPC分类号： G09G3/3648 , G02F1/133555 , G02F1/13624 , G02F1/1368 , G09G2300/0426 , G09G2300/0439 , G09G2300/0456 , G09G2300/0465 , G09G2300/0852 , G09G2320/0233
摘要： In a method for driving a liquid crystal display (LCD) device, an array substrate, a method of manufacturing the array substrate and the LCD device having the same, data signals are boosted by a first and a second boost signals up to a first and a second pixel voltages, respectively. The first and the second pixel voltages are applied to a transmissive electrode and a reflective electrode, respectively. As a result, the retardation of light passing through a liquid crystal layer on the transmissive electrode and the retardation of light of the liquid crystal layer on the reflective electrode may be controlled to be substantially equal to each other. Thus, the LCD device is driven in a transflective mode with a mono-cell gap so that the yield of the LCD device may be increased.
摘要翻译：在液晶显示（LCD）装置的驱动方法中，阵列基板，阵列基板的制造方法以及具有该阵列基板的液晶显示装置的数据信号通过第一和第二升压信号升压到第一和第二升压信号，分别为第二像素电压。第一和第二像素电压分别被施加到透射电极和反射电极。结果，可以将通过透射电极上的液晶层的光的延迟和反射电极上的液晶层的光的延迟控制为基本相等。因此，以单电池间隙的半透反射模式驱动LCD装置，从而可以提高LCD装置的产量。

2. 发明申请

US20130140529A1 ORGANIC LIGHT EMITTING DEVICE CAPABLE OF REDUCING LEAKAGE CURRENT BETWEEN PIXELS 审中-公开
标题翻译：有机发光装置，能够减少像素之间的漏电流
公开(公告)号：US20130140529A1
公开(公告)日：2013-06-06
申请号：US13538381
申请日：2012-06-29
申请人： Ju-Yeop Seong , Jae-Hoon Hwang , Jae-Hyun Kim , Jae-Young Lee , Chul-Hwan Park , Chang-Woo Shim , Sola Lee
发明人： Ju-Yeop Seong , Jae-Hoon Hwang , Jae-Hyun Kim , Jae-Young Lee , Chul-Hwan Park , Chang-Woo Shim , Sola Lee
IPC分类号： H01L27/32 , H01L51/56
CPC分类号： H01L27/3246 , H01L27/3276
摘要： Disclosed is an organic light emitting device having an improved light emitting quality, by which a leakage current generated between pixels when a current flows from one pixel to an adjacent pixel of a light emitting part may be prevented, making it possible to prevent undesired emission of light in the adjacent pixel and improve light emitting quality.
摘要翻译：公开了一种具有改善的发光质量的有机发光器件，可以防止当电流从发光部件的一个像素流向相邻像素时在像素之间产生的漏电流，从而可以防止不期望的发射相邻像素中的光，并提高发光质量。

3. 发明申请

US20110136207A1 Mutated Nucleotide Sequences of Batroxobin, Mutated Alpha Factor Secretion Signal Sequence and Processes for Preparing Batroxobin Using the Same 有权
标题翻译：巴曲酶的突变核苷酸序列，突变的α因子分泌信号序列和使用其制备巴曲酶的过程
公开(公告)号：US20110136207A1
公开(公告)日：2011-06-09
申请号：US12810902
申请日：2008-12-23
申请人： Young-Doug Sohn , Bum Joon Kim , Ok Hwan Kim , Kyoung Jun Kim , Ji Hun Shin , Sung Yu Hong , Jae Hoon Hwang , Kwang Hoe Chung
发明人： Young-Doug Sohn , Bum Joon Kim , Ok Hwan Kim , Kyoung Jun Kim , Ji Hun Shin , Sung Yu Hong , Jae Hoon Hwang , Kwang Hoe Chung
IPC分类号： C12N9/48 , C07H21/04 , C12N15/63
CPC分类号： C12N9/6418 , C07K2319/02
摘要： The present invention relates to a batroxobin-encoding nucleotide sequence and/or a mutated α-factor secretion signal sequence, and a vector and a transformant using the same. The batroxobin-encoding nucleotide sequence of this invention exhibits an excellent expression efficiency in yeast, particular Pichia pastoris and the recombinant batroxobin is obtained at 4-13 fold higher yield than natural-occurring batroxobin-encoding sequences. The protein expression system which uses the batroxobin-encoding nucleotide sequence as well as mutated α-factor secretion signal peptide sequence of this invention obtains the recombinant batroxobin at about 20-fold higher yield than natural-occurring batroxobin-encoding sequences. In addition, the recombinant batroxobin prepared using the sequence of this invention has a significantly plausible activity and stability compared with natural-occurring batroxobin.
摘要翻译：本发明涉及一种编码巴曲酶的核苷酸序列和/或突变的α因子分泌信号序列，以及使用其的载体和转化体。本发明的巴曲酶编码核苷酸序列在酵母，特别是巴斯德毕赤酵母中表现出优异的表达效率，并且以比天然存在的巴曲酶编码序列高出4-13倍的产量获得重组巴曲酶。使用巴曲酶编码核苷酸序列以及本发明的突变型α因子分泌信号肽序列的蛋白质表达系统以比天然存在的巴曲酶编码序列高出约20倍的产量获得重组巴曲酶。此外，使用本发明的序列制备的重组巴曲酶与天然存在的巴曲酶相比具有显着似乎合理的活性和稳定性。

4. 发明申请

US20100120849A1 Compositions for Treating Hyperproliferative Vascular Disorders and Cancers 有权
标题翻译：治疗过度增生性血管疾病和癌症的组合物
公开(公告)号：US20100120849A1
公开(公告)日：2010-05-13
申请号：US12528224
申请日：2007-05-23
申请人： Kwang Hoe Chung , Chwang Siek Pak , Sung Yu Hong , Soo Jung Kang , Young Doug Sohn , Jae Hoon Hwang , Eun Bok Choi , Gyu Hwan Yon , Hyeon Kyu Lee , Heui Cheol Yang
发明人： Kwang Hoe Chung , Chwang Siek Pak , Sung Yu Hong , Soo Jung Kang , Young Doug Sohn , Jae Hoon Hwang , Eun Bok Choi , Gyu Hwan Yon , Hyeon Kyu Lee , Heui Cheol Yang
IPC分类号： A61K31/47 , A61P35/00 , A61P9/00
CPC分类号： A61K31/47
摘要： The present invention relates to a pharmaceutical composition for preventing or treating hyperproliferative vascular disorders, and a pharmaceutical anticancer composition comprising the compound represented by the Formula 1. The present compounds exhibit IC50 values of less than 0.16 μM for vascular smooth muscle cells and cancer cells to effectively prevent proliferation of vascular smooth muscle cells and cancer cells, thereby ensuring prevention or treatment of hyperproliferative vascular disorders such as arteriosclerosis and restenosis, and cancers.
摘要翻译：本发明涉及一种用于预防或治疗过度增殖性血管疾病的药物组合物，以及包含由式1表示的化合物的药物抗癌组合物。本发明化合物显示血管平滑肌细胞和癌细胞的IC 50值小于0.16μM 有效防止血管平滑肌细胞和癌细胞的增殖，从而确保预防或治疗过度增生性血管疾病如动脉硬化和再狭窄以及癌症。

5. 发明授权

US08377676B2 Mutated nucleotide sequences of batroxobin, mutated α factor secretion signal sequence and processes for preparing batroxobin using the same 有权
标题翻译：巴曲酶的突变核苷酸序列，突变的α因子分泌信号序列和使用其制备巴曲酶的方法
公开(公告)号：US08377676B2
公开(公告)日：2013-02-19
申请号：US12810902
申请日：2008-12-23
申请人： Young-Doug Sohn , Bum Joon Kim , Ok Hwan Kim , Kyoung Jun Kim , Ji Hun Shin , Sung Yu Hong , Jae Hoon Hwang , Kwang Hoe Chung
发明人： Young-Doug Sohn , Bum Joon Kim , Ok Hwan Kim , Kyoung Jun Kim , Ji Hun Shin , Sung Yu Hong , Jae Hoon Hwang , Kwang Hoe Chung
IPC分类号： C12N9/74 , C12N15/57
CPC分类号： C12N9/6418 , C07K2319/02
摘要： The present invention relates to a batroxobin-encoding nucleotide sequence and/or a mutated α-factor secretion signal sequence, and a vector and a transformant using the same. The batroxobin-encoding nucleotide sequence of this invention exhibits an excellent expression efficiency in yeast, particular Pichia pastoris and the recombinant batroxobin is obtained at 4-13 fold higher yield than natural-occurring batroxobin-encoding sequences. The protein expression system which uses the batroxobin-encoding nucleotide sequence as well as mutated α-factor secretion signal peptide sequence of this invention obtains the recombinant batroxobin at about 20-fold higher yield than natural-occurring batroxobin-encoding sequences. In addition, the recombinant batroxobin prepared using the sequence of this invention has a significantly plausible activity and stability compared with natural-occurring batroxobin.
摘要翻译：本发明涉及一种编码巴曲酶的核苷酸序列和/或突变的α因子分泌信号序列，以及使用其的载体和转化体。本发明的巴曲酶编码核苷酸序列在酵母，特别是巴斯德毕赤酵母中表现出优异的表达效率，并且以比天然存在的巴曲酶编码序列高出4-13倍的产量获得重组巴曲酶。使用巴曲酶编码核苷酸序列以及本发明的突变型α因子分泌信号肽序列的蛋白质表达系统以比天然存在的巴曲酶编码序列高出约20倍的产量获得重组巴曲酶。此外，使用本发明的序列制备的重组巴曲酶与天然存在的巴曲酶相比具有显着似乎合理的活性和稳定性。

6. 发明授权

US08106071B2 Compositions for treating hyperproliferative vascular disorders and cancers 有权
标题翻译：用于治疗过度增生性血管疾病和癌症的组合物
公开(公告)号：US08106071B2
公开(公告)日：2012-01-31
申请号：US12528224
申请日：2007-05-23
申请人： Kwang Hoe Chung , Chwang Siek Pak , Sung Yu Hong , Soo Jung Kang , Young Doug Sohn , Jae Hoon Hwang , Eun Bok Choi , Gyu Hwan Yon , Hyeon Kyu Lee , Heui Cheol Yang
发明人： Kwang Hoe Chung , Chwang Siek Pak , Sung Yu Hong , Soo Jung Kang , Young Doug Sohn , Jae Hoon Hwang , Eun Bok Choi , Gyu Hwan Yon , Hyeon Kyu Lee , Heui Cheol Yang
IPC分类号： A01N43/42
CPC分类号： A61K31/47
摘要： The present invention relates to a method for treating or reducing the development of a hyperproliferative disorder, which comprises administering to a subject a composition, which comprises as an active ingredient the compound represented by the Formula 1: wherein R1, R2, R3, R4, R5, R6 and R7 independently represent hydrogen, halo, hydroxyl, cyano, amino, nitro, nitroso, carboxyl, C1-C12 alkyl, C2-C6 alkenyl, C3-C8 cycloalkyl, C5-C7 cycloalkenyl, C1-C6 alkylamino, C1-C6 alkoxy, aryl, heteroaryl, arylalkyl, arylalkenyl or alkylaryl; X and Y independently represent hydrogen, oxygen, or sulfur, bound to a carbon atom via a single or double bond; Z represents hydrogen, halo, hydroxyl, cyano, amino, nitro, nitroso, carboxyl, C1-C12 alkyl, C2-C6 alkenyl, C3-C8 cycloalkyl, C5-C7 cycloalkenyl, C1-C6 alkylamino, C1-C6 alkoxy, aryl, heteroaryl, arylalkyl, arylalkenyl, alkylaryl or —NH—R8; R8 represents hydrogen, halo, hydroxyl, cyano, amino, nitro, nitroso, carboxyl, C1-C12 alkyl, C2-C6 alkenyl, C3-C8 cycloalkyl, C5-C7 cycloalkenyl, C1-C6 alkylamino, C1-C6 alkoxy, aryl, heteroaryl, arylalkyl, arylalkenyl or alkylaryl; n is an integer of 0-3.
摘要翻译：本发明涉及一种治疗或减轻过度增殖性疾病发展的方法，其包括向受试者施用组合物，其包含作为活性成分的由式1表示的化合物：其中R1，R2，R3，R4， R5，R6和R7独立地表示氢，卤素，羟基，氰基，氨基，硝基，亚硝基，羧基，C1-C12烷基，C2-C6烯基，C3-C8环烷基，C5-C7环烯基，C1-C6烷基氨基，C1- C6烷氧基，芳基，杂芳基，芳基烷基，芳基烯基或烷基芳基; X和Y独立地表示通过单键或双键与碳原子结合的氢，氧或硫; Z代表氢，卤素，羟基，氰基，氨基，硝基，亚硝基，羧基，C1-C12烷基，C2-C6烯基，C3-C8环烷基，C5-C7环烯基，C1-C6烷基氨基，C1-C6烷氧基，杂芳基，芳基烷基，芳基烯基，烷基芳基或-NH-R8; R8代表氢，卤素，羟基，氰基，氨基，硝基，亚硝基，羧基，C1-C12烷基，C2-C6烯基，C3-C8环烷基，C5-C7环烯基，C1-C6烷基氨基，C1-C6烷氧基，杂芳基，芳基烷基，芳基烯基或烷基芳基; n为0-3的整数。

7. 发明申请

US20090315880A1 METHOD FOR DRIVING A LIQUID CRYSTAL DISPLAY DEVICE, AN ARRAY SUBSTRATE, METHOD OF MANUFACTURING THE ARRAY SUBSTRATE AND LIQUID CRYSTAL DISPLAY DEVICE HAVING THE SAME 有权
标题翻译：用于驱动液晶显示装置的方法，阵列基板，制造阵列基板的方法和具有该液晶显示装置的液晶显示装置
公开(公告)号：US20090315880A1
公开(公告)日：2009-12-24
申请号：US12485721
申请日：2009-06-16
申请人： Yong-Seok Cho , Jae-Hyun Kim , Gee-Bum Kim , Jae-Hoon Hwang
发明人： Yong-Seok Cho , Jae-Hyun Kim , Gee-Bum Kim , Jae-Hoon Hwang
IPC分类号： G09G5/36 , G02F1/133 , G02F1/1343 , G02F1/13
CPC分类号： G09G3/3648 , G02F1/133555 , G02F1/13624 , G02F1/1368 , G09G2300/0426 , G09G2300/0439 , G09G2300/0456 , G09G2300/0465 , G09G2300/0852 , G09G2320/0233
摘要： In a method for driving a liquid crystal display (LCD) device, an array substrate, a method of manufacturing the array substrate and the LCD device having the same, data signals are boosted by a first and a second boost signals up to a first and a second pixel voltages, respectively. The first and the second pixel voltages are applied to a transmissive electrode and a reflective electrode, respectively. As a result, the retardation of light passing through a liquid crystal layer on the transmissive electrode and the retardation of light of the liquid crystal layer on the reflective electrode may be controlled to be substantially equal to each other. Thus, the LCD device is driven in a transflective mode with a mono-cell gap so that the yield of the LCD device may be increased.
摘要翻译：在液晶显示（LCD）装置的驱动方法中，阵列基板，阵列基板的制造方法以及具有该阵列基板的液晶显示装置的数据信号通过第一和第二升压信号升压到第一和第二升压信号，分别为第二像素电压。第一和第二像素电压分别被施加到透射电极和反射电极。结果，可以将通过透射电极上的液晶层的光的延迟和反射电极上的液晶层的光的延迟控制为基本相等。因此，以单电池间隙的半透反射模式驱动LCD装置，从而可以提高LCD装置的产量。

8. 发明授权

US5821106A CDNA of direct-acting fibrinolytic serine protease 失效
标题翻译：直接作用的纤维蛋白溶解丝氨酸蛋白酶的CDNA
公开(公告)号：US5821106A
公开(公告)日：1998-10-13
申请号：US738413
申请日：1996-10-25
申请人： Kwang-Hoe Chung , You-Seok Koh , Jae-Hoon Hwang , Doo-Sik Kim , Yung-Dae Yun , Hong-Mo Moon
发明人： Kwang-Hoe Chung , You-Seok Koh , Jae-Hoon Hwang , Doo-Sik Kim , Yung-Dae Yun , Hong-Mo Moon
IPC分类号： C12N15/09 , A61K38/00 , A61K38/48 , A61P7/02 , C07H21/04 , C12N9/50 , C12N9/64 , C12N15/55 , C12N15/57 , C12R1/91
CPC分类号： C12N9/6418 , A61K38/00
摘要： The present invention relates to a novel cDNA of direct-acting fibrinolytic serine protease ("Salmonase") which is prepared from a Korean viper, Salmosa(Agkistrodon halys brevicaudus), and a direct-acting fibrinolytic serine protease deduced therefrom. The cDNA of direct-acting fibrinolytic serine protease contains 699 nucleotides coding for 233 amino acids, and the Salmonase translated therefrom consists of two subunits of 77 and 156 amino acids, respectively. Salmonase cDNA of the invention may be expressed in the proper systems established in the recombinant E. coli, yeast, baculovirus/insect cells and other animal cells, and the recombinant Salmonase prepared therefrom can be practically applied as an active ingredient of thrombolytic and hemostatic agents.
摘要翻译：本发明涉及由韩国蛇蝎（Salmosa）（枸杞子）和由其推断的直接作用的纤维蛋白溶解丝氨酸蛋白酶制备的直接作用的纤维蛋白溶解丝氨酸蛋白酶（“Salmonase”）的新型cDNA。直接作用的纤维蛋白溶解丝氨酸蛋白酶的cDNA含有编码233个氨基酸的699个核苷酸，转录的Salmonase分别由77个和156个氨基酸的两个亚基组成。本发明的Salmonase cDNA可以在重组大肠杆菌，酵母，杆状病毒/昆虫细胞和其他动物细胞中建立的适当系统中表达，并且由此制备的重组Salmonase可以实际应用为溶栓和止血剂的活性成分。

9. 发明申请

US20060125986A1 Array substrate, method of manufacturing the same and liquid crystal display apparatus having the same 审中-公开
标题翻译：阵列基板及其制造方法以及具有该基板的液晶显示装置
公开(公告)号：US20060125986A1
公开(公告)日：2006-06-15
申请号：US11299595
申请日：2005-12-12
申请人： Dae-Ho Choo , Ho-Min Kang , Jae-Hoon Hwang , Jeong-Min Oh , Jung-Woo Park , Min-Sung Kwon , Dae-Seung Yun
发明人： Dae-Ho Choo , Ho-Min Kang , Jae-Hoon Hwang , Jeong-Min Oh , Jung-Woo Park , Min-Sung Kwon , Dae-Seung Yun
IPC分类号： G02F1/1335
CPC分类号： G02F1/133555 , G02F1/133504 , G02F1/133528 , G02F1/1368 , G02F1/1396 , G02F2001/133357
摘要： An array substrate includes a transparent substrate, a switching device, an insulation layer, a pixel electrode, a reflective plate and an inner polarization layer. The transparent substrate has a reflective region and a transmissive region. The switching device is formed in the reflective region. The insulation layer is formed on the transparent substrate to cover the switching device. The insulation layer has a contact hole that exposes a portion of a drain electrode of the switching device. The pixel electrode is electrically connected to the drain electrode of the switching device through the contact hole. The reflective plate is electrically connected to the pixel electrode and is disposed at the reflective region. The inner polarization layer covers the reflective plate. Thus the white luminance and the contrast ratio of an LCD apparatus having the above array substrate are enhanced.
摘要翻译：阵列基板包括透明基板，开关装置，绝缘层，像素电极，反射板和内部偏振层。透明基板具有反射区域和透射区域。开关器件形成在反射区域中。绝缘层形成在透明基板上以覆盖开关装置。绝缘层具有暴露开关装置的漏电极的一部分的接触孔。像素电极通过接触孔与开关器件的漏极电连接。反射板电连接到像素电极并设置在反射区域。内部偏振层覆盖反射板。因此，具有上述阵列基板的LCD装置的白色亮度和对比度提高。

10. 发明申请

US20060082706A1 Array substrate, color filter substrate, and liquid crystal display panel having the array substrate and the color filter substrate 审中-公开
标题翻译：阵列基板，滤色器基板和具有阵列基板和滤色器基板的液晶显示面板
公开(公告)号：US20060082706A1
公开(公告)日：2006-04-20
申请号：US11215069
申请日：2005-08-29
申请人： Dae-Ho Choo , Ho-Min Kang , Jae-Hoon Hwang , Jeong-Min Oh
发明人： Dae-Ho Choo , Ho-Min Kang , Jae-Hoon Hwang , Jeong-Min Oh
IPC分类号： G02F1/1335
CPC分类号： G02F1/133528 , G02F1/133514 , G02F1/133555 , G02F1/1362
摘要： A display apparatus includes at least one pixel region having a reflection region and a transmission region. A polarizing layer of the pixel region may be formed on an uneven underlying structure surface, and may have an even opposing surface. The polarizing layer may have a first thickness the reflection area of the pixel region and a second, substantially larger thickness in the transmission area of the pixel region. The display apparatus may comprise an array substrate, a color filter substrate, and a liquid crystal material. In an array substrate, a color filter substrate and a liquid crystal display panel having the array substrate and the color filter substrate, an array substrate includes a first inner polarizing layer having a first portion where a front light is reflected and a second portion through which a back light passes. The second portion is substantially thicker than the first portion. The color filter substrate includes a second inner polarizing layer. A liquid crystal layer is positioned between the array substrate and the color filter substrate. The array substrate and the color filter substrate are combined with each other to form the liquid crystal display panel.
摘要翻译：显示装置包括具有反射区域和透射区域的至少一个像素区域。像素区域的偏振层可以形成在不均匀的下面的结构表面上，并且可以具有相反的表面。偏振层可以具有像素区域的反射区域的第一厚度和像素区域的透射区域中的第二厚度，实质上更大的厚度。显示装置可以包括阵列基板，滤色器基板和液晶材料。在阵列基板中，滤色器基板和具有阵列基板和滤色器基板的液晶显示面板，阵列基板包括具有前部光被反射的第一部分的第一内部偏光层和第二部分，第二部分背光通过。第二部分基本上比第一部分厚。滤色器基板包括第二内部偏振层。液晶层位于阵列基板和滤色器基板之间。阵列基板和滤色器基板彼此组合以形成液晶显示面板。

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