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1. 发明授权

US6134944A System and method for preconcentrating, identifying, and quantifying chemical and biological substances 失效
标题翻译：预浓缩，鉴定和定量化学和生物物质的系统和方法
公开(公告)号：US6134944A
公开(公告)日：2000-10-24
申请号：US302047
申请日：1999-04-29
申请人： Conrad M. Yu , Jackson C. Koo
发明人： Conrad M. Yu , Jackson C. Koo
IPC分类号： G01N1/40 , G01N29/02 , G01N30/12 , G01N29/18 , G01N31/06
CPC分类号： G01N29/022 , G01N30/12 , G01N1/40 , G01N2030/121 , G01N2291/02466 , G01N2291/0256 , G01N2291/0423 , G01N2291/0426
摘要： A system and method for preconcentrating, identifying, and quantifying chemical and biological substances is disclosed. An input valve directs a first volume of a sample gas to a surface acoustic wave (SAW) device. The SAW device preconcentrates and detects a mass of a substance within the sample gas. An output valve receives a second volume of the sample gas containing the preconcentrated substance from the SAW device and directs the second volume to a gas chromatograph (GC). The GC identifies the preconcentrated substance within the sample gas. A shunt valve exhausts a volume of the sample gas equal to the first volume minus the second volume away from the SAW device and the GC. The method of the present invention includes the steps of opening an input valve for passing a first volume of a sample gas to a SAW device; preconcentrating and detecting a mass of a substance within the sample gas using the SAW device; opening an output valve for passing a second volume of the sample gas containing the preconcentrated substance to a gas chromatograph (GC); and then identifying the preconcentrated substance within the sample gas using the GC.
摘要翻译：公开了一种用于预浓缩，鉴定和定量化学和生物物质的系统和方法。输入阀将第一体积的样品气体引导到表面声波（SAW）装置。 SAW器件预浓缩并检测样品气体中物质的质量。输出阀从SAW装置接收含有预浓缩物质的样品气体的第二体积，并将第二体积引导至气相色谱仪（GC）。 GC识别样品气体中的预浓缩物质。分流阀排出等于第一容积的样品气体的体积减去远离SAW器件和GC的第二体积。本发明的方法包括以下步骤：打开用于将第一体积样品气体传递到SAW器件的输入阀; 使用SAW器件预浓缩和检测样品气体内的物质的质量; 打开输出阀，用于将含有预浓缩物质的第二体积的样品气体通入气相色谱仪（GC）; 然后使用GC鉴定样品气体中的预浓缩物质。

2. 发明授权

US4257798A Method for introduction of gases into microspheres 失效
标题翻译：将气体引入微球的方法
公开(公告)号：US4257798A
公开(公告)日：1981-03-24
申请号：US61166
申请日：1979-07-26
申请人： Charles D. Hendricks , Jackson C. Koo , Allan Rosencwaig
发明人： Charles D. Hendricks , Jackson C. Koo , Allan Rosencwaig
IPC分类号： C03B19/10 , C03C11/00 , C03C3/04
CPC分类号： C03B19/1075 , C03B19/1065 , C03C11/002
摘要： A method for producing small hollow glass spheres filled with a gas by introduction of the gas during formation of the hollow glass spheres. Hollow glass microspheres having a diameter up to about 500.mu. with both thin walls (0.5 to 4.mu.) and thick walls (5 to 20.mu.) that contain various fill gases, such as Ar, Kr, Xe, Br, DT, H.sub.2, D.sub.2, He, N.sub.2, Ne, CO.sub.2, etc. in the interior thereof, can be produced by the diffusion of the fill gas or gases into the microsphere during the formation thereof from a liquid droplet of glass-forming solution. This is accomplished by filling at least a portion of the multiple-zone drop-furnace used in producing hollow microspheres with the gas or gases of interest, and then taking advantage of the high rate of gaseous diffusion of the fill gas through the wall of the gel membrane before it transforms into a glass microsphere as it is processed in the multiple-zone furnace. Almost any gas can be introduced into the inner cavity of a glass microsphere by this method during the formation of the microsphere provided that the gas is diffused into the gel membrane or microsphere prior to its transformation into glass. The process of this invention provides a significant savings of time and related expense of filling glass microspheres with various gases. For example, the time for filling a glass microballoon with 1 atmosphere of DT is reduced from about two hours to a few seconds.
摘要翻译：一种在中空玻璃球形成期间通过引入气体来生产充满气体的小型中空玻璃球的方法。直径高达约500微米的空心玻璃微球体，其两个薄壁（0.5至4微米）和厚壁（5至20微米）含有各种填充气体，例如Ar，Kr，Xe，Br，DT，H2，其内部的D2，He，N2，Ne，CO2等可以通过在从玻璃形成溶液的液滴形成期间将填充气体或气体扩散到微球中来产生。这是通过用用于生产中空微球体的多区域下落炉的至少一部分填充有感兴趣的气体或者气体来完成的，然后充分利用填充气体的气体扩散速率高于凝胶膜，然后在多区域炉中加工成玻璃微球。通过这种方法，在微球形成过程中几乎可以将任何气体引入到玻璃微球的内腔中，只要气体在其转变成玻璃之前就扩散到凝胶膜或微球体中。本发明的方法大大节省了用各种气体填充玻璃微球的时间和相关费用。例如，填充1小时DT的玻璃微球的时间从约2小时减少到几秒钟。

3. 发明授权

US06933496B2 Ion mobility sensor 失效
标题翻译：离子迁移率传感器
公开(公告)号：US06933496B2
公开(公告)日：2005-08-23
申请号：US09883665
申请日：2001-06-18
申请人： Jackson C. Koo , Conrad M. Yu
发明人： Jackson C. Koo , Conrad M. Yu
IPC分类号： G01N27/64 , B01D59/44 , H01J49/00
CPC分类号： G01N27/622
摘要： An ion mobility sensor which can detect both ion and molecules simultaneously. Thus, one can measure the relative arrival times between various ions and molecules. Different ions have different mobility in air, and the ion sensor enables measurement of ion mobility, from which one can identify the various ions and molecules. The ion mobility sensor which utilizes a pair of glow discharge devices may be designed for coupling with an existing gas chromatograph, where various gas molecules are already separated, but numbers of each kind of molecules are relatively small, and in such cases a conventional ion mobility sensor cannot be utilized.
摘要翻译：可同时检测离子和分子的离子迁移率传感器。因此，可以测量各种离子和分子之间的相对到达时间。不同的离子在空气中具有不同的迁移率，离子传感器可以测量离子迁移率，从而可以从中识别各种离子和分子。利用一对辉光放电装置的离子迁移率传感器可以被设计成与现有的气相色谱仪耦合，其中各种气体分子已被分离，但是各种分子的数量相对较小，在这种情况下，常规的离子迁移率传感器不能使用。

4. 发明授权

US06229612B1 Paper area density measurement from forward transmitted scattered light 失效
标题翻译：纸张面积密度测量从正向传播散射光
公开(公告)号：US06229612B1
公开(公告)日：2001-05-08
申请号：US09414176
申请日：1999-10-07
申请人： Jackson C. Koo
发明人： Jackson C. Koo
IPC分类号： G01N2100
CPC分类号： G01N21/3563 , G01N21/314 , G01N21/3559 , Y10S162/06
摘要： A method whereby the average paper fiber area density (weight per unit area) can be directly calculated from the intensity of transmitted, scattered light at two different wavelengths, one being a non-absorpted wavelength. Also, the method makes it possible to derive the water percentage per fiber area density from a two-wavelength measurement. In the optical measuring technique optical transmitted intensity, for example, at 2.1 microns cellulose absorption line is measured and compared with another scattered, optical transmitted intensity reference in the nearby spectrum region, such as 1.68 microns, where there is no absorption. From the ratio of these two intensities, one can calculate the scattering absorption coefficient at 2.1 microns. This absorption coefficient at this wavelength is, then, experimentally correlated to the paper fiber area density. The water percentage per fiber area density can be derived from this two-wavelength measurement approach.
摘要翻译：可以从两个不同波长的透射散射光的强度直接计算平均纸纤维面积密度（单位面积重量）的方法，一个是不吸收波长。此外，该方法可以从双波长测量得出每纤维面积密度的水百分比。在光学测量技术中，光学传输强度，例如，在2.1微米纤维素吸收线被测量，并与附近光谱区域中的另一个散射的光学透射强度参考值（例如1.68微米）进行比较，其中没有吸收。从这两个强度的比例可以计算2.1微米的散射吸收系数。然后，该波长处的吸收系数与纸纤维面积密度实验相关。每个纤维面积密度的水分百分比可以从这种双波长测量方法得出。

5. 发明授权

US5746901A Hybrid slab-microchannel gel electrophoresis system 失效
标题翻译：混合板 - 微通道凝胶电泳系统
公开(公告)号：US5746901A
公开(公告)日：1998-05-05
申请号：US628309
申请日：1996-04-05
申请人： Joseph W. Balch , Anthony V. Carrano , James C. Davidson , Jackson C. Koo
发明人： Joseph W. Balch , Anthony V. Carrano , James C. Davidson , Jackson C. Koo
IPC分类号： G01N27/447 , G01N27/26
CPC分类号： G01N27/44791
摘要： A hybrid slab-microchannel gel electrophoresis system. The hybrid system permits the fabrication of isolated microchannels for biomolecule separations without imposing the constraint of a totally sealed system. The hybrid system is reusable and ultimately much simpler and less costly to manufacture than a closed channel plate system. The hybrid system incorporates a microslab portion of the separation medium above the microchannels, thus at least substantially reducing the possibility of non-uniform field distribution and breakdown due to uncontrollable leakage. A microslab of the sieving matrix is built into the system by using plastic spacer materials and is used to uniformly couple the top plate with the bottom microchannel plate.
摘要翻译：混合板 - 微通道凝胶电泳系统。混合系统允许制造分离的微通道用于生物分子分离，而不施加全密封系统的约束。混合系统可重复使用，并且最终比封闭的通道板系统简单得多且制造成本更低。混合系统包含微通道上方的分离介质的微尺度部分，因此至少显着降低了由于不可控的泄漏引起的非均匀场分布和击穿的可能性。通过使用塑料隔板材料将筛分基质的microslab内置在系统中，并用于将顶板与底部微通道板均匀地接合。

6. 发明授权

US06355931B1 System and method for 100% moisture and basis weight measurement of moving paper 失效
标题翻译：移动纸的100％湿度和基重测量的系统和方法
公开(公告)号：US06355931B1
公开(公告)日：2002-03-12
申请号：US09386533
申请日：1999-08-30
申请人： Jose E. Hernandez , Jackson C. Koo
发明人： Jose E. Hernandez , Jackson C. Koo
IPC分类号： D21F706
CPC分类号： G01N21/3554 , D21F7/003 , D21F7/06 , G01N21/3559 , G01N33/34
摘要： A system for characterizing a set of properties for a moving substance are disclosed. The system includes: a first near-infrared linear array; a second near-infrared linear array; a first filter transparent to a first absorption wavelength emitted by the moving substance and juxtaposed between the substance and the first array; a second filter blocking the first absorption wavelength emitted by the moving substance and juxtaposed between the substance and the second array; and a computational device for characterizing data from the arrays into information on a property of the substance. The method includes the steps of: filtering out a first absorption wavelength emitted by a substance; monitoring the first absorption wavelength with a first near-infrared linear array; blocking the first wavelength from reaching a second near-infrared linear array; and characterizing data from the arrays into information on a property of the substance.
摘要翻译：公开了用于表征移动物质的一组特性的系统。该系统包括：第一近红外线性阵列; 第二近红外线性阵列; 对由所述移动物质发射并并置在所述物质和所述第一阵列之间的第一吸收波长透明的第一过滤器; 阻挡由所述移动物质发射并与所述物质和所述第二阵列并置的第一吸收波长的第二滤光器; 以及用于将来自阵列的数据表征为关于物质属性的信息的计算装置。该方法包括以下步骤：滤出由物质发射的第一吸收波长; 用第一近红外线性阵列监测第一吸收波长; 阻止第一波长到达第二近红外线性阵列; 并将来自阵列的数据表征为关于物质属性的信息。

7. 发明授权

US4257799A Method for producing small hollow spheres 失效
标题翻译：小空心球的制造方法
公开(公告)号：US4257799A
公开(公告)日：1981-03-24
申请号：US61167
申请日：1979-07-26
申请人： Allen Rosencwaig , Jackson C. Koo , John L. Dressler
发明人： Allen Rosencwaig , Jackson C. Koo , John L. Dressler
IPC分类号： C03B19/10 , C03C3/089 , C03C11/00
CPC分类号： C03B19/1075 , C03B19/1065 , C03C11/002 , C03C3/089 , Y10S376/916
摘要： A method for producing small hollow spheres of glass having an outer diameter ranging from about 100.mu. to about 500.mu. with a substantially uniform wall thickness in the range of about 0.5-20.mu.. The method involves introducing aqueous droplets of a glass-forming solution into a long vertical drop oven or furnace having varying temperature regions. In one embodiment, one of the temperature regions is lower than both the preceeding region and the subsequent region. One region utilizes a temperature of at least 200.degree. C. higher than the melting point of the glass-forming material in the solution and, for example, may be at least 3 times higher than the temperature of the preceeding region. In addition, there is a sharp temperature gradient between these regions. As each droplet of solution passes through a first region it forms into a gel membrane having a spherical shape and encapsulates the rest of the drop retained in the elastic outer surface and the water entrapped within diffuses rapidly through the thin gel membrane which causes more of the glass-forming material to go out of solution and is incorporated into the gel membrane causing it to grow in size and become hollow. thus produced hollow glass sphere has a sphericity, concentricity, and wall uniformity of better than 5%. The sphere is capable of retaining material of up to at least 100 atmospheres therein over long periods of time. In one embodiment.
摘要翻译：一种外径为约100微米至约500微米的玻璃小型中空球的制造方法，其基本均匀的壁厚在约0.5-20微米的范围内。该方法包括将玻璃形成溶液的水滴引入具有不同温度区域的长垂直下落炉或炉中。在一个实施例中，一个温度区域比先前区域和后续区域都低。一个区域使用比溶液中的玻璃形成材料的熔点高至少200℃的温度，例如可以比前一个区域的温度高至少3倍。此外，这些区域之间存在尖锐的温度梯度。当每个溶液液滴通过第一区域时，它形成具有球形形状的凝胶膜，并且封装保留在弹性外表面中的其余的液滴，并且被捕获的水迅速扩散通过薄凝胶膜，这导致更多的玻璃形成材料脱离溶液并且被引入到凝胶膜中，使其在尺寸上生长并变得中空。因此产生的中空玻璃球具有优于5％的球形度，同心度和壁均匀性。该球体能够长时间保持其中至多100个大气压的材料。在一个实施例中。

8. 发明授权

US06736000B2 Stable glow discharge detector 失效
标题翻译：稳定的辉光放电检测器
公开(公告)号：US06736000B2
公开(公告)日：2004-05-18
申请号：US09919171
申请日：2001-11-15
申请人： Jackson C. Koo , Conrad M. Yu
发明人： Jackson C. Koo , Conrad M. Yu
IPC分类号： G01N3002
CPC分类号： G01N27/70 , G01N30/64 , G01N2030/642
摘要： A highly sensitive electronic ion cell for the measurement of trace elements in He carrier gas which involves glow discharge. A constant wave (CW) stable glow discharge detector which is controlled through a biased resistor, can detect the change of electron density caused by impurities in the He carrier gas by many orders of magnitude larger than that caused by direct ionization or electron capture. The stable glow discharge detector utilizes a floating pseudo-electrode to form a probe in or near the plasma and a solid rod electrode. By using this probe, the large variation of electron density due to trace amounts of impurities can be directly measured. The solid rod electrode provides greater stability and thus easier alignment.
摘要翻译：用于测量He载气中微量元素的高灵敏度电子离子电池，涉及辉光放电。通过偏置电阻器控制的恒定波（CW）稳定辉光放电检测器可以检测由He载流子中的杂质引起的电子密度的变化比直接电离或电子捕获引起的电子密度变化多许多个数量级。稳定的辉光放电检测器利用浮动的伪电极在等离子体中或其附近形成探针，以及固体棒电极。通过使用该探针，可以直接测量由微量杂质引起的电子密度的大变化。实心棒电极提供更大的稳定性，从而更容易对准。

9. 发明授权

US06457347B1 Glow discharge detector 失效
标题翻译：发光放电检测器
公开(公告)号：US06457347B1
公开(公告)日：2002-10-01
申请号：US09464668
申请日：1999-12-15
申请人： Jackson C. Koo , Conrad M. Yu
发明人： Jackson C. Koo , Conrad M. Yu
IPC分类号： G01N3000
CPC分类号： G01N27/70 , G01N30/64 , G01N2030/642
摘要： A highly sensitive electronic ion cell for the measurement of trace elements in He carrier gas which involves glow discharge. A constant wave (CW) glow discharge detector which is controlled through a biased resistor, can detect the change of electron density caused by impurities in the He carrier gas by many orders of magnitude larger than that caused by direct ionization or electron capture. The glow discharge detector utilizes a floating pseudo-electrode to form a probe in or near the plasma. By using this probe, the large variation of electron density due to trace amounts of impurities can be directly measured.
摘要翻译：用于测量He载气中微量元素的高灵敏度电子离子电池，涉及辉光放电。通过偏置电阻器控制的恒定（CW）辉光放电检测器可以检测由He载流子中的杂质引起的电子密度的变化比直接电离或电子俘获引起的电子密度变化多许多个数量级。辉光放电检测器利用浮动伪电极在等离子体中或附近形成探针。通过使用该探针，可以直接测量由微量杂质引起的电子密度的大变化。

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