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1. 发明授权

US09940440B2 Detecting and responding to software and hardware anomalies in a fluid delivery system 有权
公开(公告)号：US09940440B2
公开(公告)日：2018-04-10
申请号：US13096756
申请日：2011-04-28
申请人： Irfan Z. Ali , Donald L. Villalta , Scott A. Sarkinen
发明人： Irfan Z. Ali , Donald L. Villalta , Scott A. Sarkinen
IPC分类号： A61M5/168 , G06F19/00 , A61M5/142
CPC分类号： G16H20/17 , A61M5/14276 , A61M2005/14208 , A61M2205/18 , A61M2205/3523 , A61M2205/3561 , A61M2205/3569 , A61M2205/50 , G06F19/00 , G06F19/3468
摘要： A total dose of a therapeutic agent to be delivered to a patient by an infusion device over a total period of time is automatically divided into a plurality of unit doses to be delivered to the patient over a plurality of unit periods of time. The infusion device is automatically programmed to deliver one of the unit doses of the therapeutic agent to the patient over its respective unit period of time, after which the one unit dose is delivered, and a determination is made of whether an error occurred in delivering the one unit dose to the patient. Delivery of the total dose of the therapeutic agent to the patient may include iteratively automatically programming the infusion device to deliver successive unit doses upon determining that no error occurred in delivering a previous unit dose to the patient. Accordingly, the risk of improperly dosing the patient with the therapeutic agent in an event of a software or hardware anomaly within the infusion device is prevented or reduced.

2. 发明授权

US09737660B2 Drug infusion device with controllable valve 有权
公开(公告)号：US09737660B2
公开(公告)日：2017-08-22
申请号：US13217981
申请日：2011-08-25
申请人： Reginald D. Robinson , Mary E. Robischon , Bernard Q. Li , Irfan Z. Ali , Steven R. Christenson , Keith A. Miesel
发明人： Reginald D. Robinson , Mary E. Robischon , Bernard Q. Li , Irfan Z. Ali , Steven R. Christenson , Keith A. Miesel
IPC分类号： A61M5/168 , A61M39/22 , A61M5/142
CPC分类号： A61M5/16827 , A61M5/14276 , A61M5/1684 , A61M39/223 , A61M2205/3523 , A61M2205/3569 , A61M2210/1003
摘要： A therapeutic fluid delivery device that includes at least one controllable valve is generally described. In one example, an implantable therapeutic fluid delivery system includes a first fluid pathway configured to convey a first therapeutic fluid and a second fluid pathway configured to convey a second therapeutic fluid, the second fluid pathway being separate from the first fluid pathway. The therapeutic fluid delivery system includes a valve connected to the first fluid pathway and the second fluid pathway, and a processor configured to control actuation of the valve to open and close the first fluid pathway and to open and close the second fluid pathway.

3. 发明申请

US20120271380A1 ADAPTIVELY CONFIGURING THE VALIDATION TIMEOUT OF A SESSION KEY USED FOR SECURING COMMUNICATION WITH AN IMPLANTABLE MEDICAL DEVICE 有权
标题翻译：适应性地配置用于通过可植入医疗设备进行通信的会议密钥的验证超时
公开(公告)号：US20120271380A1
公开(公告)日：2012-10-25
申请号：US13446074
申请日：2012-04-13
申请人： Earle T. Roberts , Irfan Z. Ali , Donald L. Villalta
发明人： Earle T. Roberts , Irfan Z. Ali , Donald L. Villalta
IPC分类号： A61N1/36
CPC分类号： H04W12/04 , A61N1/37252 , A61N1/37258 , H04L9/088 , H04L9/0891 , H04L63/0435 , H04L63/068 , H04L2209/805 , H04L2209/88
摘要： Methods, devices and systems are disclosed that provide for dynamically adjusting the valid lifespan of a session key for wireless communication sessions established between at least two medical devices. Adjusting the session key lifetime balances protecting the communications link so that it is not unnecessarily susceptible to eavesdropping by third parties or other interference while obviating the need for a user to repeatedly perform access control steps.
摘要翻译：公开了提供用于动态调整在至少两个医疗设备之间建立的无线通信会话的会话密钥的有效寿命的方法，设备和系统。调整保护通信链路的会话密钥生存期余额，使得不会不必要地容易受第三方窃听或其他干扰，同时避免用户重复执行访问控制步骤。

4. 发明申请

US20090137980A1 METHOD AND APPARATUS FOR MULTI-INPUT STEPWISE INFUSION PRESCRIPTION 审中-公开
标题翻译：用于多输入步骤输注处方的方法和装置
公开(公告)号：US20090137980A1
公开(公告)日：2009-05-28
申请号：US12324434
申请日：2008-11-26
申请人： Irfan Z. Ali
发明人： Irfan Z. Ali
IPC分类号： A61M5/168
CPC分类号： A61M5/142 , A61M5/168 , A61M5/1723 , A61M2230/04 , A61M2230/201 , A61M2230/42 , A61M2230/63 , G06F19/3468
摘要： A drug infusion system includes a drug delivery module which delivers a drug in each of a series of sequential time slots over a period of time. The drug delivery module is controlled by a controller which is configured to cause the drug delivery module to deliver said drug in the series of sequential time slots in a manner defined by a formula in which a quantitative characteristic of drug delivery in each time slot is a function of a past drug delivery profile and at least one of: a) a medical professional-provided profile, b) a patient-chosen parameter, and c) a non-variable parameter. The formula may be a function of a medical professional-provided profile and a non-variable parameter may be a parameter chosen by a medical professional. The past drug delivery profile may include a drug delivery parameter in a previous time slot. The patient-chosen parameter may include an input from the patient characterizing the patient's condition.
摘要翻译：药物输注系统包括药物递送模块，其在一段时间内在一系列连续时隙中的每一个中递送药物。药物递送模块由控制器控制，所述控制器被配置为使得药物递送模块以下述方式定义的连续时间序列中的药物递送：其中每个时隙中药物递送的定量特征为过去药物递送概况的功能和以下中的至少一个：a）医疗专业提供的简档，b）患者选择的参数，以及c）非变量参数。公式可以是医学专业人员提供的简档的函数，并且非变量参数可以是由医学专业人员选择的参数。过去的药物递送分布可以包括前一时间段中的药物递送参数。患者选择的参数可以包括来自表征患者状况的患者的输入。

5. 发明授权

US09687603B2 Volume monitoring for implantable fluid delivery devices 有权
公开(公告)号：US09687603B2
公开(公告)日：2017-06-27
申请号：US12762064
申请日：2010-04-16
申请人： Cynthia R. Nelson Konen , Irfan Z. Ali , Keith A. Miesel , Scott L. Kalpin
发明人： Cynthia R. Nelson Konen , Irfan Z. Ali , Keith A. Miesel , Scott L. Kalpin
IPC分类号： A61M5/142 , A61M5/168
CPC分类号： A61M5/1684 , A61M5/14276 , A61M5/16854 , A61M2005/14264 , A61M2205/3331 , A61M2205/3379 , A61M2205/3389
摘要： Unexpected changes in the volume of therapeutic fluid in the reservoir of a fluid delivery device are detected based on changes in the pressure of the reservoir measured over a period of time by a pressure sensor. Additionally, an ambulatory reservoir fluid volume gauge is provided to indicate an actual volume of therapeutic fluid in a fluid delivery device reservoir. The actual volume of therapeutic fluid in the reservoir indicated by the ambulatory reservoir fluid volume gauge is determined based on changes in the pressure in the reservoir measured over a period of time by a pressure sensor.

6. 发明授权

US08562591B2 Drug infusion system and method adapted to start during programming cycle 有权
标题翻译：药物输液系统和方法适用于在编程周期中启动
公开(公告)号：US08562591B2
公开(公告)日：2013-10-22
申请号：US13551945
申请日：2012-07-18
申请人： Irfan Z. Ali , David C. Ullestad
发明人： Irfan Z. Ali , David C. Ullestad
IPC分类号： A61K9/22 , A61M31/00
CPC分类号： A61M5/14276 , A61M5/172 , A61M2205/3523
摘要： Drug infusion system capable of delivering a fluid medication to a patient and method for doing same is described. An implantable drug delivery device is capable of delivering the fluid medication at a programmable rate to the patient under control of an original programming cycle having a plurality of steps in a plurality of time slots beginning at a starting time. The programming cycle specifies the programmable rate for each of the plurality of steps. An external controller is capable of storing a program representative of the original programming cycle in the implantable drug delivery device at a programming time. The drug infusion system adjusts the implantable drug delivery device so that the original programming cycle will begin at a time during the original programming cycle adjusted for the programming time.
摘要翻译：描述了能够向患者输送流体药物的药物输注系统和用于进行相同的方法。可植入药物递送装置能够以在开始时间开始的多个时隙中具有多个步骤的原始编程周期的控制下以可编程速率将流体药物递送给患者。编程周期指定多个步骤中的每个步骤的可编程速率。外部控制器能够在编程时将代表原始编程周期的程序存储在可植入药物递送装置中。药物注射系统调整可植入药物递送装置，使得原始编程周期将在针对编程时间调整的原始编程周期期间的一个时间开始。

7. 发明申请

US20120283639A1 DETECTING EMPTY MEDICAL PUMP RESERVOIR 有权
标题翻译：检测清洁液体储存罐
公开(公告)号：US20120283639A1
公开(公告)日：2012-11-08
申请号：US13553270
申请日：2012-07-19
申请人： Irfan Z. Ali , Keith A. Miesel , Scott L. Kalpin , Scott A. Sarkinen
发明人： Irfan Z. Ali , Keith A. Miesel , Scott L. Kalpin , Scott A. Sarkinen
IPC分类号： A61M5/168
CPC分类号： A61M5/14276 , A61B5/1116 , A61M5/14212 , A61M5/172 , A61M2205/18 , A61M2205/3317 , A61M2205/50
摘要： A medical device system comprises a reservoir configured to store a therapeutic fluid and a medical pump configured to deliver the therapeutic fluid from the reservoir to a patient. The system also comprises a sensor that can detect a characteristic associated with the pump and a processor to determine if the characteristic detected indicates the reservoir is empty or near empty. The characteristic may comprise a characteristic of a noise made by an actuator within the pump at the end of a pump stroke.
摘要翻译：医疗设备系统包括被配置为存储治疗流体的储存器和被配置为将治疗流体从储存器输送到患者的医用泵。该系统还包括可以检测与泵相关联的特征的传感器和处理器，以确定检测到的特征是否指示储存器为空或接近空。该特征可以包括在泵冲程结束时由泵内的致动器产生的噪声的特性。

8. 发明授权

US08241270B2 Drug infusion system and method adapted to start during programming cycle 有权
标题翻译：药物输液系统和方法适用于在编程周期中启动
公开(公告)号：US08241270B2
公开(公告)日：2012-08-14
申请号：US10837500
申请日：2004-04-30
申请人： Irfan Z. Ali , David C. Ullestad
发明人： Irfan Z. Ali , David C. Ullestad
IPC分类号： A61K9/22 , A61M31/00
CPC分类号： A61M5/14276 , A61M5/172 , A61M2205/3523
摘要： Drug infusion system capable of delivering a fluid medication to a patient and method for doing same. An implantable drug delivery device is capable of delivering the fluid medication at a programmable rate to the patient under control of an original programming cycle having a plurality of steps in a plurality of time slots beginning at a starting time. The programming cycle specifies the programmable rate for each of the plurality of steps. An external controller is capable of storing a program representative of the original programming cycle in the implantable drug delivery device at a programming time. The drug infusion system adjusts the implantable drug delivery device so that the original programming cycle will begin at a time during the original programming cycle adjusted for the programming time.
摘要翻译：能够向患者输送流体药物的药物输注系统和进行相同操作的方法。可植入药物递送装置能够以在开始时间开始的多个时隙中具有多个步骤的原始编程周期的控制下以可编程速率将流体药物递送给患者。编程周期指定多个步骤中的每个步骤的可编程速率。外部控制器能够在编程时将代表原始编程周期的程序存储在可植入药物递送装置中。药物注射系统调整可植入药物递送装置，使得原始编程周期将在针对编程时间调整的原始编程周期期间的一个时间开始。

9. 发明申请

US20110264034A1 MEDICAL THERAPY MODIFICATION AUTHORIZATION TECHNIQUES 审中-公开
标题翻译：医疗治疗改造授权技术
公开(公告)号：US20110264034A1
公开(公告)日：2011-10-27
申请号：US12768466
申请日：2010-04-27
申请人： Earle T. Roberts , Irfan Z. Ali , Emem D. Akpan , Scott L. Kalpin , Varaz Shahmirian , William J. Mitchell
发明人： Earle T. Roberts , Irfan Z. Ali , Emem D. Akpan , Scott L. Kalpin , Varaz Shahmirian , William J. Mitchell
IPC分类号： A61M37/00
CPC分类号： G06F19/3418 , G06F19/3468
摘要： Techniques for programming therapy delivered a patient via a medical device are described. One example technique includes receiving a request for a modification to a therapy delivered to a patient via medical device, transmitting a request to a remote networking device for authorization for the modification to the therapy in response to the request for the modification to the therapy, receiving a response to the request for authorization, where the response to the request for authorization indicates whether the requested modification is authorized, and modifying the therapy according to the requested modification when the requested modification is determined to be authorized. In some examples, the medical device includes a medical fluid delivery device.
摘要翻译：描述了通过医疗装置递送患者的编程治疗技术。一个示例性技术包括：接收对通过医疗设备递送给患者的治疗的修改的请求，响应于对治疗的修改的请求，向远程网络设备发送请求以授权修改治疗，接收对授权请求的响应，其中对请求授权的响应指示所请求的修改是否被授权，以及当所请求的修改被确定为被授权时，根据所请求的修改来修改治疗。在一些示例中，医疗装置包括医疗流体输送装置。

10. 发明申请

US20110172741A1 PROXIMITY BASED SELECTION OF AN IMPLANTABLE MEDICAL DEVICE FOR FAR FIELD COMMUNICATION 有权
公开(公告)号：US20110172741A1
公开(公告)日：2011-07-14
申请号：US12686971
申请日：2010-01-13
申请人： Earle T. Roberts , Donald L. Villalta , David S. Slack , Irfan Z. Ali , Sudheendhar Raghavendran , Nathan A. Torgerson , Garrett R. Sipple
发明人： Earle T. Roberts , Donald L. Villalta , David S. Slack , Irfan Z. Ali , Sudheendhar Raghavendran , Nathan A. Torgerson , Garrett R. Sipple
IPC分类号： A61N1/08
CPC分类号： H04W4/80 , A61N1/37217 , A61N1/37252 , A61N1/37282 , H04L9/3271 , H04L63/0492 , H04L63/18 , H04L67/12 , H04L2209/805 , H04L2209/88 , H04W8/005 , H04W12/06 , H04W88/06
摘要： Devices and systems provide for proximity based selection of an implantable medical device for far field communication with an external device. By using a proximity communication that is limited to the IMD of interest during the selection process, the external device can eliminate those IMDs that are in range of far field communications but are able to receive the proximity communication. Thus, information may be shared via a proximity communication that is validated via a far field communication, or shared via a far field communication as a challenge and then validated via a proximity communication. The proximity communication may be used to initially limit the number of devices that respond to a discovery request and then subsequently used to select the intended implantable medical device as well as automatically select the appropriate therapy application corresponding to the selected IMD.

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