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1. 发明授权

US4994263A Medicinal combination used in photochemotherapy 失效
标题翻译：药物组合用于光化学治疗
公开(公告)号：US4994263A
公开(公告)日：1991-02-19
申请号：US517520
申请日：1990-04-30
申请人： Gerard Lang , Andre Deflandre , Irena Beck
发明人： Gerard Lang , Andre Deflandre , Irena Beck
IPC分类号： A61K31/365
CPC分类号： A61K31/365 , Y10S514/861 , Y10S514/863 , Y10S514/864 , Y10S514/886 , Y10S514/887 , Y10S514/937 , Y10S514/938 , Y10S514/939 , Y10S514/944 , Y10S514/945 , Y10S514/96 , Y10S514/969
摘要： A composition for treatment and treatment of certain skin diseases is disclosed. The treatment combines furocoumarins, UV-A radiation, and a benzylidene-camphor derivative. The composition and treatment produces the desirable results of the furocoumarin/UV-A radiation treatment without the undesirable phototoxic side effects.
摘要翻译：公开了一种用于治疗和治疗某些皮肤疾病的组合物。该治疗结合了呋喃香豆素，UV-A辐射和亚苄基 - 樟脑衍生物。组合物和处理产生不需要光毒性副作用的呋喃香豆素/ UV-A辐射处理的期望结果。

2. 发明授权

US4950478A Cosmetic compositions containing natural essences and benzylidenecamphor derivatives 失效
标题翻译：含有天然精华和亚苄基or or衍生物的化妆品组合物
公开(公告)号：US4950478A
公开(公告)日：1990-08-21
申请号：US573143
申请日：1984-01-23
申请人： Gerard Lang , Andre Deflandre , Irena Beck
发明人： Gerard Lang , Andre Deflandre , Irena Beck
IPC分类号： A61K8/35 , A61K8/41 , A61K8/46 , A61K8/92 , A61Q17/04
CPC分类号： A61K8/35 , A61K8/416 , A61K8/466 , A61K8/922 , A61Q17/04 , Y10S424/05
摘要： The present invention relates to a cosmetic composition comprising a natural essence containing a phototoxic dose of furocoumarin, and 0.01 to 2% by weight of at least one benzylidenecamphor derivative filtering out UV-A radiation and chosen from among 3-p-oxybenzylidenebornan-2-ones, 3,3'-terephthalylidenedicamphors optionally sulfonated in the 10-position of the camphor, p-(3-methylidenecamphor)-cinnamic acid derivatives, 3,3'-terephthalylidenedicampho-10-sulfonamides or 3,3'-terephthalylidenedicampho-10,10'-disulfonamides.It is also possible to incorporate into the composition a UV-B filter chosen from among: benzylidenecamphor, p-methylbenzylidenecamphor, benzylidenecamphor derivatives containing a quaternary ammonium radical on the benzene nucleus in the para position relative to the bornylidene radical, benzylidenecamphor derivatives sulphonated on the methyl radical in the 10-position of the camphor or in the 3'-position of 4'-position on the benzene nucleus, p-methylbenzylidene-camphor derivatives substituted on the p-methyl group, or other 3-benzylidenecamphor derivatives filtering out UV-B radiation.The effect of the benzylidenecamphor derivative is to deactivate the furocoumarins excited by UV radiation and to reduce their phototoxicity.
摘要翻译：本发明涉及一种化妆品组合物，其包含含有光毒性剂量的呋喃香豆素的天然精华和0.01至2重量％的过滤掉UV-A辐射的至少一种亚苄基猝灭衍生物，并选自3-对 - 氧亚苄基 - 樟脑的10位任选磺化的3,3'-对苯二甲酰脒，对 - （3-甲基en or or or am am am am am am am am am am am am am am am am am am am 10 10 10 10，，，，10 3 10 10 10 10 10 10 10 10 10 10 10 10 ，10'-二磺酰胺。也可以在组合物中加入选自以下的UV-B过滤器：亚苄基樟脑，对甲基亚苄基樟脑，在相对于甘草基的对位的苯核上含有季铵基的亚苄基or or衍生物，其上磺化的亚苄基am or衍生物樟脑10位或甲苯4'-位的3'-位上的甲基，对甲基取代的对甲基亚苄基 - 樟脑衍生物或其它3-亚苄基am or衍生物过滤出紫外 -B辐射。亚苄基脒衍生物的作用是使由紫外线辐射激发的呋喃香豆素失活并降低其光毒性。

3. 发明授权

US4731200A Alcoholic or aqueous-alcoholic compositions containing natural essences and benzylidene-camphor derivatives 失效
标题翻译：含有天然香精和亚苄基 - 樟脑衍生物的醇或含水组合物
公开(公告)号：US4731200A
公开(公告)日：1988-03-15
申请号：US885392
申请日：1986-07-18
申请人： Gerard Lang , Andre Deflandre , Irena Beck
发明人： Gerard Lang , Andre Deflandre , Irena Beck
IPC分类号： C09K3/00 , A61K8/00 , A61K8/30 , A61K8/34 , A61K8/35 , A61K8/37 , A61K8/41 , A61K8/46 , A61K8/49 , A61K8/92 , A61K8/97 , A61K31/125 , A61K31/37 , A61P17/00 , A61Q13/00 , A61Q17/04 , A61Q19/02 , A61Q90/00 , C11B9/00 , A61K7/46
CPC分类号： A61K8/416 , A61K8/35 , A61K8/466 , A61K8/922 , A61Q17/04
摘要： The present invention relates to an alcoholic or aqueous-alcoholic composition comprising a natural essence containing a phototoxic dose of furocoumarin, and 0.01 to 2% by weight of at least one benzylidenecamphor derivative filtering out UV-A radiation and chosen from among 3-p-oxybenzylidenebornan-2-ones, 3,3'-terephthalylidenedicamphors optionally sulphonated in the 10-position of the camphor, p-(3-methylidenecamphor)cinnamic acid derivatives, 3,3'-terephthalylidenedicampho-10-sulphonamides or 3,3'-terephthalylidenedicampho-10,10'-disulphonamides. It is also possible to incorporate into the composition a UV-B filter chosen from among benzylidenecamphor, p-methylbenzylidenecamphor, benzylidenecamphor derivatives containing a quaternary ammonium radical on the benzene nucleus in the para position relative to the bornylidene radical, benzylidenecamphor derivatives sulphonated on the methyl radical in the 10-position of the camphor or in the 3'-position or 4'-position on the benzene nucleus, p-methylbenzylidenecamphor derivatives substituted on the p-methyl group, or other 3-benzylidenecamphor derivatives filtering out UV-B radiation.Application: perfumes, toilet waters, eaux de cologne and shaving lotions.
摘要翻译：本发明涉及包含含有光毒剂量的呋喃香豆素的天然精华和0.01-2重量％的至少一种亚苄基猝灭衍生物的酒精或含水醇组合物，其过滤掉UV-A辐射并选自3-对 - 对苯二甲酰亚苯基-2-酮，樟脑10位中任选磺化的3,3'-对苯二甲酰基樟脑，对 - （3-甲基亚甲基樟脑）肉桂酸衍生物，3,3'-对苯二甲酰亚苯基二磷杂-10-磺酰胺或3,3'- 对苯二甲酰己二磷-10,10'-二磺酰胺。在组合物中还可以将选自亚苄基樟脑，对甲基亚苄基樟脑中的UV-B过滤器，在相对于亚生乙酰基的对位的苯核上含有季铵基的亚苄基am or衍生物，在甲基上磺化的亚苄基am or衍生物在樟脑的10位或苯核上的3'-位或4'-位，在对甲基上取代的对甲基亚苄基脒衍生物或其它过滤出UV-B辐射的3-亚苄基or or衍生物。适用范围：香水，马桶水，洗发水及洗发水。

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