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1. 发明申请

US20140024992A1 Cylindrical Structure Having Lumen to Be Implanted Into Human Body 审中-公开
标题翻译：具有流明入人体的圆柱形结构
公开(公告)号：US20140024992A1
公开(公告)日：2014-01-23
申请号：US14007645
申请日：2012-07-10
申请人： Eun-Jin Kim , In-Su Baek , Ji-Hye Park , Dae-Joong Kim
发明人： Eun-Jin Kim , In-Su Baek , Ji-Hye Park , Dae-Joong Kim
IPC分类号： A61M27/00
CPC分类号： A61M27/002 , A61F2/06 , A61F2250/0035 , A61F2250/0067 , A61L31/048 , A61L31/06 , A61L31/10 , A61L31/148 , A61L31/16 , A61L2300/416 , A61L2300/43 , A61M1/3655
摘要： A cylindrical structure having a lumen to be implanted into a human body. The cylindrical structure has a coating layer formed on at least one part of an inner surface of either or both ends of the cylindrical structure, wherein the coating layer includes a polymer for drug release control and a bioactive material.
摘要翻译：具有待植入人体的内腔的圆柱形结构。圆柱形结构体具有形成在圆柱形结构的两端或两端的内表面的至少一部分上的涂层，其中涂层包括用于药物释放控制的聚合物和生物活性材料。

2. 发明申请

US20110029069A1 Bioactive Material Coating Method And Tube 有权
标题翻译：生物活性材料涂层方法和管
公开(公告)号：US20110029069A1
公开(公告)日：2011-02-03
申请号：US12866235
申请日：2009-01-19
申请人： Dae-Joong Kim , In-Su Baek , Jong-Sang Park , Hye-Yeong Nam , Chengzhe Bai
发明人： Dae-Joong Kim , In-Su Baek , Jong-Sang Park , Hye-Yeong Nam , Chengzhe Bai
IPC分类号： A61F2/01 , B05D7/00
CPC分类号： A61L27/507 , A61L27/16 , A61L27/54 , A61L27/56 , A61L2300/416 , A61L2420/02 , A61M1/3655 , C08L27/18
摘要： A method for coating bioactive material and a structured coated with a bioactive material are disclosed. The bioactive material coating method includes: flowing a coating solution, produced as a bioactive material is dissolved in a mixed solvent, inside a structure having a lumen; and coating the bioactive material on at least one of inner and outer surfaces of the structure, with different concentrations. The mixed solvent is mixed with two or more solvents having different features. The occurrence of the strangulation of blood vessels and inflammation can be reduced. An increase in the size of the myofibroblast is not suppressed. The coating solution is produced as a medication is dissolved in a mixed solvent, where the mixed solvent is produced as a polar solvent and a nonpolar solvent are mixed with each other at a certain ratio.
摘要翻译：公开了一种用于涂覆生物活性材料和涂覆有生物活性材料的结构的方法。生物活性物质涂布方法包括：将作为生物活性物质生产的涂布溶液溶解在具有内腔的结构内的混合溶剂中; 以及在所述结构的内表面和外表面中的至少一个上以不同的浓度涂覆所述生物活性材料。将混合溶剂与具有不同特征的两种或更多种溶剂混合。可以减少血管和炎症的窒息的发生。肌成纤维细胞的大小的增加不被抑制。将药物溶解在混合溶剂中时，制成涂布溶液，混合溶剂作为极性溶剂和非极性溶剂以一定的比例混合。

3. 发明授权

US08075940B2 Bioactive material coating method and tube 有权
标题翻译：生物活性材料涂层方法和管
公开(公告)号：US08075940B2
公开(公告)日：2011-12-13
申请号：US12866235
申请日：2009-01-19
申请人： Dae-Joong Kim , In-Su Baek , Jong-Sang Park , Hye-Yeong Nam , Chengzhe Bai
发明人： Dae-Joong Kim , In-Su Baek , Jong-Sang Park , Hye-Yeong Nam , Chengzhe Bai
IPC分类号： A61L33/00
CPC分类号： A61L27/507 , A61L27/16 , A61L27/54 , A61L27/56 , A61L2300/416 , A61L2420/02 , A61M1/3655 , C08L27/18
摘要： A method for coating bioactive material and a structured coated with a bioactive material are disclosed. The bioactive material coating method includes: flowing a coating solution, produced as a bioactive material is dissolved in a mixed solvent, inside a structure having a lumen; and coating the bioactive material on at least one of inner and outer surfaces of the structure, with different concentrations. The mixed solvent is mixed with two or more solvents having different features. The occurrence of the strangulation of blood vessels and inflammation can be reduced. An increase in the size of the myofibroblast is not suppressed. The coating solution is produced as a medication is dissolved in a mixed solvent, where the mixed solvent is produced as a polar solvent and a nonpolar solvent are mixed with each other at a certain ratio.
摘要翻译：公开了一种用于涂覆生物活性材料和涂覆有生物活性材料的结构的方法。生物活性物质涂布方法包括：将作为生物活性物质生产的涂布溶液溶解在具有内腔的结构内的混合溶剂中; 以及在所述结构的内表面和外表面中的至少一个上以不同的浓度涂覆所述生物活性材料。将混合溶剂与具有不同特征的两种或更多种溶剂混合。可以减少血管和炎症的窒息的发生。肌成纤维细胞的大小的增加不被抑制。将药物溶解在混合溶剂中时，制成涂布溶液，混合溶剂是作为极性溶剂制备混合溶剂，非极性溶剂以一定比例混合。

4. 发明申请

US20110183064A1 Method For Coating Medication On Medical Article 有权
标题翻译：医疗用涂料用药方法
公开(公告)号：US20110183064A1
公开(公告)日：2011-07-28
申请号：US12809054
申请日：2010-01-21
申请人： Jong-Sang Park , Dae-Joong Kim , In-Su Baek , Chengzhe Bai
发明人： Jong-Sang Park , Dae-Joong Kim , In-Su Baek , Chengzhe Bai
IPC分类号： A61B17/04
CPC分类号： A61B17/06166 , A61B2017/00526 , A61B2017/00893 , A61L17/005 , A61L17/145 , A61L2300/40 , Y10T428/29 , Y10T428/2913
摘要： A method for coating medication for a medical product is disclosed. A technique for coating gel in a viscous semisolid state is provided to facilitate coating of medication. Coating of medication on an article can be facilitated using gel, and coating of medication on an article such as an article made of silk and an article made of polypropylene can be further facilitated.
摘要翻译：公开了一种用于医疗产品的药物涂布方法。提供用于涂覆粘性半固体状态的凝胶的技术以便于涂覆药物。可以使用凝胶来促进制品上的药物涂层，并且可以进一步促进在诸如由丝制品制成的制品和由聚丙烯制成的制品上涂敷药物。

5. 发明授权

US08399044B2 Method for coating medication on medical article 有权
标题翻译：医疗用品涂药方法
公开(公告)号：US08399044B2
公开(公告)日：2013-03-19
申请号：US12809054
申请日：2010-01-21
申请人： Jong-Sang Park , Dae-Joong Kim , In-Su Baek , Chengzhe Bai
发明人： Jong-Sang Park , Dae-Joong Kim , In-Su Baek , Chengzhe Bai
IPC分类号： A61F13/00 , A61F13/02 , A61K9/28 , A61K9/70 , A61B17/04 , A61B17/10 , A61L17/00 , A61M31/00 , B01J13/00 , B05D3/00 , B32B19/00 , D02G3/00
CPC分类号： A61B17/06166 , A61B2017/00526 , A61B2017/00893 , A61L17/005 , A61L17/145 , A61L2300/40 , Y10T428/29 , Y10T428/2913
摘要： A method for coating medication for a medical product is disclosed. A technique for coating gel in a viscous semisolid state is provided to facilitate coating of medication. Coating of medication on an article can be facilitated using gel, and coating of medication on an article such as an article made of silk and an article made of polypropylene can be further facilitated.
摘要翻译：公开了一种用于医疗产品的药物涂布方法。提供用于涂覆粘性半固体状态的凝胶的技术以便于涂覆药物。可以使用凝胶来促进制品上的药物涂层，并且可以进一步促进在诸如由丝制品制成的制品和由聚丙烯制成的制品上涂敷药物。

6. 发明申请

US20110178592A1 Implantable Tube And Coating Method Thereof 审中-公开
标题翻译：可植入管及其涂层方法
公开(公告)号：US20110178592A1
公开(公告)日：2011-07-21
申请号：US12922674
申请日：2009-09-29
申请人： Dae-Joong Kim , In-Su Baek , Chul-Soo Gim , Sang-Ho Kim
发明人： Dae-Joong Kim , In-Su Baek , Chul-Soo Gim , Sang-Ho Kim
IPC分类号： A61F2/01 , B05D7/00
CPC分类号： A61M1/3655 , A61L27/50 , A61L27/54
摘要： An implantable tube to be implanted in a human body so as to be used as a circulation path, and a coating method thereof are disclosed. The implantable tube is a structure with a lumen coated with a bioactive material containing a material promoting fusing of the structure implanted in the body with ambient tissues. When the structure coated with a bioactive material is implanted in the body, the reaction of fusing the structure with ambient tissues can be promoted to shorten a stabilization period required until dialysis begins. In addition, since a chemical drug, medicament for inducing the generation of a growth factor promoting fusing of the structure with ambient tissues, is used, the structure can be easily coated.
摘要翻译：本发明公开了一种植入人体以便作为循环路径使用的可植入管及其涂敷方法。可植入管是具有内部涂覆有生物活性材料的内部结构，其包含促进植入体内结构与周围组织的融合的材料。当涂覆有生物活性材料的结构植入体内时，可以促进将结构与周围组织融合的反应，以缩短透析开始所需的稳定期。此外，由于使用化学药物，因此促进生成促进结构与周围组织融合的生长因子的药物，因此可以容易地进行结构的涂布。

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