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1. 发明授权

US09248232B2 Analyte monitoring and fluid dispensing system 有权
标题翻译：分析物监测和流体分配系统
公开(公告)号：US09248232B2
公开(公告)日：2016-02-02
申请号：US13511578
申请日：2010-11-30
申请人： Ofer Yodfat , Eli Znati , Illai Gescheit , Avraham Neta , Offer Levy
发明人： Ofer Yodfat , Eli Znati , Illai Gescheit , Avraham Neta , Offer Levy
IPC分类号： A61M31/00 , A61M5/168 , A61M5/142 , A61B5/145 , A61B5/1486 , A61M5/14 , A61M5/145 , A61M5/172 , A61B5/00 , A61M5/00
CPC分类号： A61M5/14248 , A61B5/1451 , A61B5/14532 , A61B5/14865 , A61B5/4839 , A61M5/002 , A61M5/1413 , A61M5/1456 , A61M5/1723 , A61M2005/14252 , A61M2005/14268 , A61M2005/1726 , A61M2205/3317 , A61M2205/3569 , A61M2205/3592 , A61M2209/01 , A61M2230/201
摘要： Embodiments of the present disclosure are directed to a skin adherable device for delivering therapeutic fluid into a body of a patient. In some embodiments, the device includes a monitoring apparatus, a pump, and a tip for delivering the therapeutic fluid into the body of the patient and for monitoring bodily analyte in the body of the patient. The pump may continuously deliver the therapeutic fluid to the body of the patient and the monitoring apparatus may continuously monitor bodily analytes of the patient.
摘要翻译：本公开的实施例涉及用于将治疗性流体输送到患者体内的皮肤粘附装置。在一些实施例中，该装置包括监测装置，泵和用于将治疗流体输送到患者体内并用于监测患者体内的身体分析物的尖端。泵可以将治疗流体连续递送到患者体内，并且监测装置可以连续地监测患者的身体分析物。

2. 发明授权

US08641672B2 Infusion and sensing device with battery charging and data transferring mechanisms 有权
标题翻译：具有电池充电和数据传输机制的输液和感应装置
公开(公告)号：US08641672B2
公开(公告)日：2014-02-04
申请号：US12921824
申请日：2009-03-10
申请人： Ofer Yodfat , Avihoo P. Keret , Avraham Neta , Illai Gescheit , Tsabar Mor
发明人： Ofer Yodfat , Avihoo P. Keret , Avraham Neta , Illai Gescheit , Tsabar Mor
IPC分类号： A61M1/00
CPC分类号： A61M5/14248 , A61M5/14216 , A61M5/14232 , A61M5/1456 , A61M5/14566 , A61M5/1723 , A61M2005/14268 , A61M2005/14573 , A61M2005/1726 , A61M2205/0266 , A61M2205/3561 , A61M2205/3569 , A61M2205/3592 , A61M2205/52 , A61M2205/8206 , A61M2205/8243 , A61M2205/8262 , A61M2205/8293 , A61M2209/086
摘要： Disclosed is a portable ambulatory fluid delivery device. The device includes a dispensing unit to dispense therapeutic fluid, the dispensing unit including one or more rechargeable batteries, a housing to retain the one or more rechargeable batteries, a reservoir to contain the therapeutic fluid, a driving mechanism to cause delivery of the therapeutic fluid from the reservoir to a user's body, and at least one electrical connector to be coupled to a recharging unit to direct electrical power received from the recharging unit to recharge the one or more rechargeable batteries. At least a portion of the housing is securable to a skin of the user.
摘要翻译：公开了一种便携式便携式流体输送装置。所述装置包括分配单元以分配治疗流体，所述分配单元包括一个或多个可再充电电池，用于保持所述一个或多个可再充电电池的壳体，用于容纳所述治疗流体的储存器，用于使所述治疗流体输送的驱动机构以及至少一个要连接到再充电单元的电连接器，以引导从所述再充电单元接收的电力对所述一个或多个可再充电电池进行再充电。壳体的至少一部分可固定到使用者的皮肤上。

3. 发明授权

US08465460B2 Device for drug delivery 有权
标题翻译：药物输送装置
公开(公告)号：US08465460B2
公开(公告)日：2013-06-18
申请号：US12733009
申请日：2008-07-31
申请人： Ofer Yodfat , Gavriel J. Iddan , Illai Gescheit
发明人： Ofer Yodfat , Gavriel J. Iddan , Illai Gescheit
IPC分类号： A61M5/178
CPC分类号： A61M5/14248 , A61M5/1413 , A61M5/14232 , A61M5/1424 , A61M5/14244 , A61M5/1454 , A61M5/1456 , A61M2005/1405 , A61M2005/14268 , A61M2205/071 , A61M2209/045
摘要： Disclosed is an ambulatory therapeutic fluid delivery device (10). The device includes at least one housing (200) connectable to a cannula (250), the at least one housing retaining a reservoir (220) to hold the therapeutic fluid. The device also includes a mechanically powered pumping mechanism (150) to cause delivery of at least some of the fluid from the reservoir, and a power-transfer mechanism to transfer manually-delivered power provided by a user to mechanically actuate the pumping mechanism.
摘要翻译：公开了一种移动式治疗液输送装置（10）。该装置包括可连接到套管（250）的至少一个壳体（200），所述至少一个壳体保持储存器（220）以保持治疗流体。该装置还包括机械动力泵送机构（150），用于使来自储存器的至少一些流体的输送以及动力传递机构传递由使用者提供的手动输送的动力以机械地致动泵送机构。

4. 发明授权

US09387033B2 Device and method for enhanced subcutaneous insulin absorption 有权
标题翻译：增强皮下胰岛素吸收的装置和方法
公开(公告)号：US09387033B2
公开(公告)日：2016-07-12
申请号：US13060799
申请日：2009-08-27
申请人： Ofer Yodfat , Gali Shapira , Illai Gescheit
发明人： Ofer Yodfat , Gali Shapira , Illai Gescheit
IPC分类号： A61M5/14 , A61M5/172 , A61B18/14 , A61M5/142 , A61B18/20 , A61B17/00 , A61M5/158 , A61M37/00
CPC分类号： A61B18/14 , A61B18/20 , A61B2017/00765 , A61M5/1413 , A61M5/14248 , A61M5/1723 , A61M2005/14268 , A61M2005/1587 , A61M2037/0007 , A61M2205/36 , A61M2205/3653 , A61M2230/201
摘要： Products and methods directed to the improved infusion of fluids are disclosed. Such products and methods can be used to more efficiently and efficaciously administer therapeutic pharmaceuticals to a subject in need of treatment. In many instances, the systems comprise a therapeutic fluid delivery system and a mechanism for enhancing the absorption of the therapeutic fluid. The enhancement of the absorption of the therapeutic fluid is generally performed locally i.e., at or near the site of administration of the therapeutic fluid. The system and methods can be used to deliver any number of therapeutic fluids including but not limited to insulin.
摘要翻译：公开了针对改进的流体输注的产品和方法。这些产品和方法可以用于更有效和有效地将治疗药物施用于需要治疗的受试者。在许多情况下，该系统包括治疗流体递送系统和用于增强治疗性流体吸收的机构。治疗性液体的吸收的增强通常在局部进行，即在治疗性流体的给药部位处或附近。该系统和方法可用于递送任何数量的治疗流体，包括但不限于胰岛素。

5. 发明申请

US20110009824A1 INFUSION AND SENSING DEVICE WITH BATTERY CHANGING AND DATA TRANSFERRING MECHANISMS 有权
标题翻译：具有电池更换和数据传输机制的输入和感应装置
公开(公告)号：US20110009824A1
公开(公告)日：2011-01-13
申请号：US12921824
申请日：2009-03-10
申请人： Ofer Yodfat , Avihoo P. Keret , Avraham Neta , Illai Gescheit , Tsabar Mor
发明人： Ofer Yodfat , Avihoo P. Keret , Avraham Neta , Illai Gescheit , Tsabar Mor
IPC分类号： A61M5/142 , H02J7/00
CPC分类号： A61M5/14248 , A61M5/14216 , A61M5/14232 , A61M5/1456 , A61M5/14566 , A61M5/1723 , A61M2005/14268 , A61M2005/14573 , A61M2005/1726 , A61M2205/0266 , A61M2205/3561 , A61M2205/3569 , A61M2205/3592 , A61M2205/52 , A61M2205/8206 , A61M2205/8243 , A61M2205/8262 , A61M2205/8293 , A61M2209/086
摘要： Disclosed is a portable ambulatory fluid delivery device. The device includes a dispensing unit to dispense therapeutic fluid, the dispensing unit including one or more rechargeable batteries, a housing to retain the one or more rechargeable batteries, a reservoir to contain the therapeutic fluid, a driving mechanism to cause delivery of the therapeutic fluid from the reservoir to a user's body, and at least one electrical connector to be coupled to a recharging unit to direct electrical power received from the recharging unit to recharge the one or more rechargeable batteries. At least a portion of the housing is securable to a skin of the user.
摘要翻译：公开了一种便携式便携式流体输送装置。所述装置包括分配单元以分配治疗流体，所述分配单元包括一个或多个可再充电电池，用于保持所述一个或多个可再充电电池的壳体，用于容纳所述治疗流体的储存器，用于使所述治疗流体输送的驱动机构以及至少一个要连接到再充电单元的电连接器，以引导从所述再充电单元接收的电力对所述一个或多个可再充电电池进行再充电。壳体的至少一部分可固定到使用者的皮肤上。

6. 发明授权

US09808574B2 Insertion device 有权
公开(公告)号：US09808574B2
公开(公告)日：2017-11-07
申请号：US12215255
申请日：2008-06-25
申请人： Ofer Yodfat , Avraham Neta , Illai Gescheit
发明人： Ofer Yodfat , Avraham Neta , Illai Gescheit
IPC分类号： A61M5/142 , A61B5/00 , A61M5/158 , A61M5/42 , A61B5/145 , A61M5/14
CPC分类号： A61M5/14248 , A61B5/14532 , A61B5/6849 , A61M5/1413 , A61M5/158 , A61M5/422 , A61M2005/14252 , A61M2005/1426 , A61M2005/1581 , A61M2005/1585 , A61M2205/3606 , A61M2205/362 , A61M2205/3673
摘要： An insertion apparatus and a method for use with a device for delivery of a therapeutic fluid into a body of a patient and/or for sensing of a bodily analyte are disclosed. The apparatus includes a housing adapted for loading therein at least one cannula cartridge unit having a protective member. The protective member accommodates at least one penetrating cartridge having a subcutaneously insertable element and a penetrating member. The apparatus includes a displacement mechanism capable of protracting the penetrating cartridge towards the body of the patient, where protraction of the penetrating cartridge results in insertion of the subcutaneously insertable element into the body of the patient.

7. 发明申请

US20100292651A1 DEVICE FOR DRUG DELIVERY 有权
标题翻译：用于药物递送的装置
公开(公告)号：US20100292651A1
公开(公告)日：2010-11-18
申请号：US12733009
申请日：2008-07-31
申请人： Ofer Yodfat , Gavriel J. Iddan , Illai Gescheit
发明人： Ofer Yodfat , Gavriel J. Iddan , Illai Gescheit
IPC分类号： A61M5/175 , A61M5/142 , A61M5/158
CPC分类号： A61M5/14248 , A61M5/1413 , A61M5/14232 , A61M5/1424 , A61M5/14244 , A61M5/1454 , A61M5/1456 , A61M2005/1405 , A61M2005/14268 , A61M2205/071 , A61M2209/045
摘要： Disclosed is an ambulatory therapeutic fluid delivery device (10). The device includes at least one housing (200) connectable to a cannula (250), the at least one housing retaining a reservoir (220) to hold the therapeutic fluid. The device also includes a mechanically powered pumping mechanism (150) to cause delivery of at least some of the fluid from the reservoir, and a power-transfer mechanism to transfer manually-delivered power provided by a user to mechanically actuate the pumping mechanism.
摘要翻译：公开了一种移动式治疗液输送装置（10）。该装置包括可连接到套管（250）的至少一个壳体（200），所述至少一个壳体保持储存器（220）以保持治疗流体。该装置还包括机械动力泵送机构（150），用于使来自储存器的至少一些流体的输送以及动力传递机构传递由使用者提供的手动输送的动力以机械地致动泵送机构。

8. 发明申请

US20100286601A1 MAINTAINING GLYCEMIC CONTROL DURING EXERCISE 有权
标题翻译：练习期间保持健康控制
公开(公告)号：US20100286601A1
公开(公告)日：2010-11-11
申请号：US12810864
申请日：2008-12-25
申请人： Ofer Yodfat , Gali Shapira , Illai Gescheit
发明人： Ofer Yodfat , Gali Shapira , Illai Gescheit
IPC分类号： A61M5/14
CPC分类号： A61M5/14244 , A61M5/14248 , A61M5/1723 , A61M2005/14208 , A61M2205/056 , A61M2205/3569 , G06F19/00 , G06F19/3456 , G06F19/3481
摘要： Devices, apparatuses and methods for controlling blood-glucose levels during exercise are described. For example, an insulin infusion apparatus can include a control module to regulate a rate of therapeutic fluid release into a body of a patient based on a determined therapeutic fluid requirement profile, and a dispensing unit to release therapeutic fluid at the regulated rate. The methods and devices can be implemented by receiving a first value corresponding to a first glucose concentration before an exercise activity of a user; receiving a second value corresponding to a second glucose concentration after the exercise activity for the user; determining a glucose concentration change based on a difference between the second value and the first value; modifying a basal rate based on a comparison of the glucose concentration change with a predetermined threshold value; and, recording the modified basal rate in a computer-readable memory device.
摘要翻译：描述了用于在运动期间控制血糖水平的装置，装置和方法。例如，胰岛素输注装置可以包括控制模块，用于基于确定的治疗流体需求曲线来调节治疗性流体释放到患者体内的速率，以及分配单元，其以调节速率释放治疗性流体。方法和装置可以通过在用户的运动活动之前接收对应于第一葡萄糖浓度的第一值来实现; 在用户的运动活动之后接收对应于第二葡萄糖浓度的第二值; 基于第二值和第一值之间的差来确定葡萄糖浓度变化; 基于葡萄糖浓度变化与预定阈值的比较来改变基础率; 并且将修改的基本速率记录在计算机可读存储器件中。

9. 发明申请

US20080319414A1 Insertion device 有权
标题翻译：插入装置
公开(公告)号：US20080319414A1
公开(公告)日：2008-12-25
申请号：US12215255
申请日：2008-06-24
申请人： Ofer Yodfat , Avraham Neta , Illai Gescheit
发明人： Ofer Yodfat , Avraham Neta , Illai Gescheit
IPC分类号： A61M5/20 , A61M5/32 , A61B5/145
CPC分类号： A61M5/14248 , A61B5/14532 , A61B5/6849 , A61M5/1413 , A61M5/158 , A61M5/422 , A61M2005/14252 , A61M2005/1426 , A61M2005/1581 , A61M2005/1585 , A61M2205/3606 , A61M2205/362 , A61M2205/3673
摘要： An insertion apparatus and a method for use with a device for delivery of a therapeutic fluid into a body of a patient and/or for sensing of a bodily analyte are disclosed. The apparatus includes a housing adapted for loading therein at least one cannula cartridge unit having a protective member. The protective member accommodates at least one penetrating cartridge having a subcutaneously insertable element and a penetrating member. The apparatus includes a displacement mechanism capable of protracting the penetrating cartridge towards the body of the patient, where protraction of the penetrating cartridge results in insertion of the subcutaneously insertable element into the body of the patient.
摘要翻译：公开了一种用于将治疗流体输送到患者体内和/或感测身体分析物的装置的插入装置和方法。该装置包括适于在其中装载至少一个具有保护构件的套管套筒单元的壳体。保护构件容纳至少一个具有皮下可插入元件和穿透构件的穿透盒。该装置包括能够朝向患者身体延伸穿透药筒的移位机构，其中穿透药筒的伸出导致皮下可插入元件插入患者体内。

10. 发明授权

US09173993B2 Fluid delivery device 有权
标题翻译：流体输送装置
公开(公告)号：US09173993B2
公开(公告)日：2015-11-03
申请号：US12451427
申请日：2008-05-11
申请人： Ofer Yodfat , Avraham Neta , Doron Bushi , Illai Gescheit
发明人： Ofer Yodfat , Avraham Neta , Doron Bushi , Illai Gescheit
IPC分类号： A61M5/148 , A61M5/145 , A61M5/142 , F04B43/12
CPC分类号： A61M5/14248 , A61M5/14232 , A61M5/1452 , A61M5/148 , A61M5/172 , A61M2005/14208 , A61M2005/14252 , A61M2005/14268 , A61M2202/0007 , A61M2205/3569 , A61M2205/3592 , A61M2210/04 , F04B43/1269
摘要： A method and an apparatus for delivery of a therapeutic fluid to the body of a patient are provided. The apparatus includes a dispensing unit having a driving mechanism and a pumping mechanism for pumping the fluid to the body of the patient and a collapsible reservoir fillable with the therapeutic fluid for delivery thereof to the body of the patient.
摘要翻译：提供了一种用于将治疗流体递送到患者体内的方法和装置。该装置包括分配单元，其具有驱动机构和用于将流体泵送到患者身体的泵送机构和可与治疗流体填充的可折叠储存器，用于将其输送到患者身体。

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