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1. 发明申请

US20110200724A1 Preparation Method of Cooked Rice in Aseptic Packing System Using Embryo Bud-Containing Rice 审中-公开
标题翻译：用含芽芽稻的无菌包装系统煮熟米饭的制备方法
公开(公告)号：US20110200724A1
公开(公告)日：2011-08-18
申请号：US12745338
申请日：2008-11-27
申请人： Hyo-Young Jeong , Chang Yong Lee , Tae Hyeong Kim , Jun Bong Choi , Hye-Won Shin , Min-Soo Kim
发明人： Hyo-Young Jeong , Chang Yong Lee , Tae Hyeong Kim , Jun Bong Choi , Hye-Won Shin , Min-Soo Kim
IPC分类号： A23L1/182
CPC分类号： A23L7/196
摘要： A method is provided for preparing an instant embryo bud-retaining white rice product. The rice is polished like white rice using a low-speed, uniform pressure method to keep embryo buds and is rich in nutrients and has white rice's flavor. Its lipid oxidation is similar to that of white rice. The immersion time period of the embryo bud-retaining white rice is controlled so as not to generate sticky materials after the immersion, thus allowing effective sterilization of the rice. Therefore, the instant embryo bud-retaining white rice can be stored at room temperature for 6 months or longer.
摘要翻译：提供了一种制备即时胚芽保留白米制品的方法。使用低速，均匀的压力方法将米饭像白米抛光，以保持胚芽，营养丰富，并具有白米的味道。其脂质氧化与白米相似。控制胚芽保留白米的浸泡时间，以便在浸渍后不产生粘性物质，从而允许米的有效灭菌。因此，即时胚芽保留白米可以在室温下储存6个月以上。

2. 发明授权

US07427269B2 Accurate method to characterize airway nitric oxide using different breath-hold times including axial diffusion of nitric oxide using heliox and breath hold 有权
标题翻译：使用不同的呼吸时间来确定气道一氧化氮的精确方法，包括使用氦气和呼气保持的一氧化氮的轴向扩散
公开(公告)号：US07427269B2
公开(公告)日：2008-09-23
申请号：US11636027
申请日：2006-12-08
申请人： Steven C. George , Hye-Won Shin , Peter Condorelli
发明人： Steven C. George , Hye-Won Shin , Peter Condorelli
IPC分类号： A61B5/08
CPC分类号： A61B5/0813 , A61B5/083
摘要： An apparatus and method to characterize NO gas exchange dynamics in human lungs comprising the steps of: (1) performing a series of breath hold maneuvers of progressively increasingly breath hold times, each breath hold maneuver comprising a) inhaling a gas, b) holding a breath for a selected time duration, and c) exhaling at a flow rate which is uncontrolled but which is effective to ensure evacuation of the airway space and (2) measuring airway NO parameters during consecutive breath hold maneuvers. As a result disease states of the lungs are diagnosed using the measured airway NO parameters.
摘要翻译：一种用于表征人肺中NO气体交换动力学的装置和方法，包括以下步骤：（1）执行逐渐增加的呼吸保持时间的一系列呼吸保持机动，每次呼吸保持机动包括a）吸入气体，b）呼吸选择的持续时间，以及c）以不受控制的流速呼出，但是有效地确保排空气道空间，以及（2）在连续呼吸机动期间测量气道NO参数。因此，使用测量的气道NO参数来诊断肺的疾病状态。

3. 发明申请

US20070282214A1 TECHNIQUE TO CHARACTERIZE PROXIMAL AND PERIPHERAL NITRIC OXIDE EXCHANGE USING CONSTANT FLOW EXHALATIONS AND AN AXIAL DIFFUSION MODEL 审中-公开
标题翻译：使用恒定流量排放和轴向扩散模型来表征临近和外部氧化氮交换的技术
公开(公告)号：US20070282214A1
公开(公告)日：2007-12-06
申请号：US11748895
申请日：2007-05-15
申请人： Steven C. George , Peter Condorelli , Hye-Won Shin
发明人： Steven C. George , Peter Condorelli , Hye-Won Shin
IPC分类号： A61B5/08
CPC分类号： A61B5/08 , A61B5/082
摘要： An apparatus and method to characterize NO gas exchange dynamics in human lungs, including performing a plurality of breathing maneuvers of substantially constant flow rates within a predetermined range, measuring data relating to at least one of an NO concentration and an NO elimination rate as a function of exhaled volume or exhalation flow rate, applying a lung model to the measured data, and obtaining at least one parameter indicative of disease states of the lung based on the lung model and the measured data, wherein the lung model, when applied in the predetermined range, predicts a substantially linear relationship between the NO elimination rate and the exhalation flow rate.
摘要翻译：表征人肺中NO气体交换动力学的装置和方法，包括在预定范围内执行基本恒定流速的多个呼吸机动，测量与NO浓度和NO消除率中的至少一个有关的数据作为功能呼出体积或呼出流量，将肺模型应用于测量数据，以及基于肺模型和测量数据获得指示肺的疾病状态的至少一个参数，其中当以预定的方式应用肺模型时预测NO排出率和呼气流量之间的基本线性关系。

4. 发明授权

US08716309B2 Pharmaceutical composition comprising pyridone derivatives 有权
标题翻译：包含吡啶酮衍生物的药物组合物
公开(公告)号：US08716309B2
公开(公告)日：2014-05-06
申请号：US13980819
申请日：2012-01-30
申请人： Cheol Young Maeng , Young Koo Jang , Su Bong Cha , Hye Won Shin , Chan Mi Joung , Hwa Ryun Cha , Eun Jung Yi
发明人： Cheol Young Maeng , Young Koo Jang , Su Bong Cha , Hye Won Shin , Chan Mi Joung , Hwa Ryun Cha , Eun Jung Yi
IPC分类号： A01N43/90 , A61K31/44 , C07D453/02
CPC分类号： C07D453/02
摘要： A pyridone derivative compound and a pharmaceutically acceptable salt, isomer, solvate or hydrate thereof, and a preventive or therapeutic pharmaceutical composition for cognitive disorders that includes the pyridone derivative compound or a pharmaceutically acceptable salt, isomer, solvate or hydrate thereof.
摘要翻译：吡啶酮衍生物化合物及其药学上可接受的盐，异构体，溶剂合物或水合物，以及包括吡啶酮衍生化合物或其药学上可接受的盐，异构体，溶剂化物或水合物的认知障碍的预防或治疗药物组合物。

5. 发明申请

US20130317059A1 PHARMACEUTICAL COMPOSITION COMPRISING PYRIDONE DERIVATIVES 有权
公开(公告)号：US20130317059A1
公开(公告)日：2013-11-28
申请号：US13980819
申请日：2012-01-30
申请人： Cheol Young Maeng , Young Koo Jang , Su Bong Cha , Hye Won Shin , Chan Mi Joung , Hwa Ryun Cha , Eun Jung Yi
发明人： Cheol Young Maeng , Young Koo Jang , Su Bong Cha , Hye Won Shin , Chan Mi Joung , Hwa Ryun Cha , Eun Jung Yi
IPC分类号： C07D453/02
CPC分类号： C07D453/02
摘要： A pyridone derivative compound and a pharmaceutically acceptable salt, isomer, solvate or hydrate thereof, and a preventive or therapeutic pharmaceutical composition for cognitive disorders that includes the pyridone derivative compound or a pharmaceutically acceptable salt, isomer, solvate or hydrate thereof.

6. 发明授权

US08597941B2 Bioreactor for quantification of headspace VOC content from cultures 有权
标题翻译：用于定量来自培养物的顶空VOC含量的生物反应器
公开(公告)号：US08597941B2
公开(公告)日：2013-12-03
申请号：US12875768
申请日：2010-09-03
申请人： Hye-Won Shin , Brandon J. Umber , Donald R. Blake , Dan M. Cooper
发明人： Hye-Won Shin , Brandon J. Umber , Donald R. Blake , Dan M. Cooper
IPC分类号： C12M1/107 , C12M3/00 , C12M1/21
CPC分类号： C12M41/34
摘要： A bioreactor for sampling the headspace above cells includes a glass reactor vessel having an interior space and a plurality of valves operatively coupled to the interior space of the glass reactor vessel. The bioreactor includes a sample holder configured to reside in the interior space. The interior space includes a charge of air with a known composition of volatile organic gases and, in some instances, doped with carbon dioxide. The sample holder may hold cells, bacteria, or viruses. The headspace may be sampled after incubation to determine the VOC content or content of specific VOC constituents. Examples include acetaldehyde and hexanaldehyde.
摘要翻译：用于对细胞上方的顶部空间进行采样的生物反应器包括具有内部空间的玻璃反应器容器和可操作地耦合到玻璃反应器容器的内部空间的多个阀。生物反应器包括配置成驻留在内部空间中的样品保持器。内部空间包括具有已知组成的挥发性有机气体的空气，并且在一些情况下，掺杂有二氧化碳。样品架可以容纳细胞，细菌或病毒。孵育后可以对顶空进行采样，以确定VOC含量或特定VOC成分的含量。实例包括乙醛和己醛。

7. 发明申请

US20130296340A1 PHARMACEUTICAL COMPOSITION COMPRISING PYRIDONE DERIVATIVES 有权
公开(公告)号：US20130296340A1
公开(公告)日：2013-11-07
申请号：US13980821
申请日：2012-01-30
申请人： Cheol Young Maeng , Young Koo Jang , Su Bong Cha , Hye Won Shin , Chan Mi Joung , Eun Jung Yi
发明人： Cheol Young Maeng , Young Koo Jang , Su Bong Cha , Hye Won Shin , Chan Mi Joung , Eun Jung Yi
IPC分类号： C07D453/02
CPC分类号： A61K31/439 , A61K9/0053 , A61K31/4709 , A61K31/4725 , A61K31/497 , C07D453/02
摘要： A pyridone derivative compound and a pharmaceutically acceptable salt, isomer, solvate or hydrate thereof, and a preventive or therapeutic pharmaceutical composition for cognitive disorders that includes the pyridone derivative compound or a pharmaceutically acceptable salt, isomer, solvate or hydrate thereof.

8. 发明申请

US20120231118A1 METHOD FOR PREPARING SOYBEAN PASTE 审中-公开
标题翻译：制备大豆酱的方法
公开(公告)号：US20120231118A1
公开(公告)日：2012-09-13
申请号：US13509525
申请日：2010-10-18
申请人： Eun Seok Jang , Jae Hyun Chang , Sung Hun Lee , Hye Won Shin , Won Dae Chung , Kang Pyo Lee
发明人： Eun Seok Jang , Jae Hyun Chang , Sung Hun Lee , Hye Won Shin , Won Dae Chung , Kang Pyo Lee
IPC分类号： A23L1/20
CPC分类号： A23L27/50 , A23L11/07 , A23L11/09
摘要： Disclosed is a method for preparing a soybean paste including: flaking or crushing raw soybeans, immersing the resulting flaked or crushed soybeans in water, followed by cooking and cooling, homogeneously mixing the soybeans with koji bacteria and a bean or grain powder, followed by fermenting and drying, and mixing the meju with table salt and distilled water and aging the resulting mixture. In accordance with the method, the soybeans are flaked or crushed to advantageously reduce hydrating and cooking periods of soybeans, form cracks on the soybean surfaces and increase surface areas, and allow beneficial microorganisms to easily use nutrients contained in soybeans, thus increase enzyme production, considerably reduce fermentation period of meju and aging period of soybean paste, obtain manufacturing soybean pastes with superior quality and improve production efficiency.
摘要翻译：公开了一种制备大豆酱的方法，包括：将生的大豆剥落或破碎，将得到的片状或破碎的大豆浸入水中，随后烹饪和冷却，将大豆与曲霉菌和豆或粉末粉末均匀混合，随后发酵并干燥，并将食盐与餐盐和蒸馏水混合，并使所得混合物老化。根据该方法，将大豆片状或粉碎以有利地减少大豆的水合和烹煮期，在大豆表面形成裂纹并增加表面积，并允许有益微生物容易地使用大豆中含有的营养物质，从而增加酶的产生，大大减少了酱油的发酵时间和大豆酱的老化时间，获得了制造质量优异，提高生产效率的大豆糊。

9. 发明授权

US08952165B2 Pharmaceutical composition comprising pyridone derivatives 有权
标题翻译：含吡啶酮衍生物的药物组合物
公开(公告)号：US08952165B2
公开(公告)日：2015-02-10
申请号：US13980821
申请日：2012-01-30
申请人： Cheol Young Maeng , Young Koo Jang , Su Bong Cha , Hye Won Shin , Chan Mi Joung , Eun Jung Yi
发明人： Cheol Young Maeng , Young Koo Jang , Su Bong Cha , Hye Won Shin , Chan Mi Joung , Eun Jung Yi
IPC分类号： C07D453/02 , C07D417/14 , C07D471/08 , A61K31/4748
CPC分类号： A61K31/439 , A61K9/0053 , A61K31/4709 , A61K31/4725 , A61K31/497 , C07D453/02
摘要： A pyridone derivative compound and a pharmaceutically acceptable salt, isomer, solvate or hydrate thereof, and a preventive or therapeutic pharmaceutical composition for cognitive disorders that includes the pyridone derivative compound or a pharmaceutically acceptable salt, isomer, solvate or hydrate thereof.
摘要翻译：吡啶酮衍生物化合物及其药学上可接受的盐，异构体，溶剂合物或水合物，以及包括吡啶酮衍生化合物或其药学上可接受的盐，异构体，溶剂化物或水合物的认知障碍的预防或治疗药物组合物。

10. 发明申请

US20070149891A1 Accurate method to characterize airway nitric oxide using different breath-hold times including axial diffusion of nitric oxide using heliox and breath hold 有权
标题翻译：使用不同的呼吸时间来确定气道一氧化氮的精确方法，包括使用氦气和呼气保持的一氧化氮的轴向扩散
公开(公告)号：US20070149891A1
公开(公告)日：2007-06-28
申请号：US11636027
申请日：2006-12-08
申请人： Steven George , Hye-Won Shin , Peter Condorelli
发明人： Steven George , Hye-Won Shin , Peter Condorelli
IPC分类号： A61B1/00 , A61B5/08
CPC分类号： A61B5/0813 , A61B5/083
摘要： An apparatus and method to characterize NO gas exchange dynamics in human lungs comprising the steps of: (1) performing a series of breath hold maneuvers of progressively increasingly breath hold times, each breath hold maneuver comprising a) inhaling a gas, b) holding a breath for a selected time duration, and c) exhaling at a flow rate which is uncontrolled but which is effective to ensure evacuation of the airway space and (2) measuring airway NO parameters during consecutive breath hold maneuvers. As a result disease states of the lungs are diagnosed using the measured airway NO parameters.
摘要翻译：一种用于表征人肺中NO气体交换动力学的装置和方法，包括以下步骤：（1）执行逐渐增加的呼吸保持时间的一系列呼吸保持机动，每次呼吸保持机动包括a）吸入气体，b）呼吸选择的持续时间，以及c）以不受控制的流速呼出，但是有效地确保排空气道空间，以及（2）在连续呼吸机动期间测量气道NO参数。因此，使用测量的气道NO参数来诊断肺的疾病状态。

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