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1. 发明授权

US08561609B2 Dry powder inhaler 有权
标题翻译：干粉吸入器
公开(公告)号：US08561609B2
公开(公告)日：2013-10-22
申请号：US13313778
申请日：2011-12-07
申请人： Martin Donovan , Jacques Pappo , Hugh Smyth
发明人： Martin Donovan , Jacques Pappo , Hugh Smyth
IPC分类号： A61M16/00 , A61M15/00 , B05D7/14 , B65D83/06
CPC分类号： A61M15/0028 , A61M15/0003 , A61M15/001 , A61M15/0021 , A61M15/0036 , A61M15/0063 , A61M16/127 , A61M2202/064 , A61M2205/43
摘要： A dry powder inhaler includes a chamber holding an actuator to which a powdered medicament is adhered. Air is drawn into the chamber through an inlet flow channel and exits through an outlet flow channel. The actuator oscillates in response to the air flow, dislodging powdered medicament to be entrained in the air flow and delivered to the patient. A retaining member prevents the actuator from exiting the chamber. Thus, the medicament may be delivered to the patient without the use of carrier particles.
摘要翻译：干粉吸入器包括容纳致动器的室，粉末状药剂被附着到该致动器上。空气通过入口流动通道被吸入室内，并通过出口流动通道离开。执行器响应于空气流动而振荡，将粉末状药物移走以夹带在空气流中并输送到患者体内。保持构件防止致动器离开室。因此，药物可以不使用载体颗粒递送到患者。

2. 发明授权

US08024283B2 Enforcing rule selection on user inboxes 失效
标题翻译：对用户收件箱执行规则选择
公开(公告)号：US08024283B2
公开(公告)日：2011-09-20
申请号：US12899814
申请日：2010-10-07
申请人： Sean Callanan , Al Chakra , Sonya Purcell , Hugh Smyth
发明人： Sean Callanan , Al Chakra , Sonya Purcell , Hugh Smyth
IPC分类号： G06F17/00 , G06N5/02
CPC分类号： G06Q10/107
摘要： Rule selection is enforced on user email inboxes using an inbox monitor and administrative rules at an email server. The inbox monitor includes a first agent for identifying inactive user inboxes from email messages stored at the email database, and a second agent for identifying, from the inactive user inboxes identified by the first agent, user inboxes without appropriate user rules activated. For each user inbox identified by the second agent, administrative rules are applied to the user inbox if the user inbox has been inactive for at least a predetermined period of time. If the user inbox has not been inactive for at least the predetermined period of time, a notification message is sent to a user associated with the user inbox. The notification message informs the user that administrative rules will be applied to the user inbox if appropriate user rules are not activated.
摘要翻译：使用收件箱监视器和电子邮件服务器上的管理规则在用户电子邮件收件箱上强制执行规则选择。收件箱监视器包括用于从存储在电子邮件数据库中的电子邮件标识非活动用户收件箱的第一代理，以及用于从未激活的适当用户规则的第一代理标识的非活动用户收件箱中识别用户收件箱的第二代理。对于由第二代理识别的每个用户收件箱，如果用户收件箱已经处于非活动状态至少预定的一段时间，则管理规则被应用于用户收件箱。如果用户收件箱至少在预定的时间段内尚未被停用，则向与用户收件箱相关联的用户发送通知消息。如果没有激活适当的用户规则，通知消息通知用户管理规则将被应用于用户收件箱。

3. 发明申请

US20090037543A1 SYSTEM AND METHOD TO PRIORITIZE CHAT ALERTS BASED ON AN ORGANIZATIONAL HIERARCHICAL CHAIN 审中-公开
公开(公告)号：US20090037543A1
公开(公告)日：2009-02-05
申请号：US11840626
申请日：2007-08-17
申请人： Sean Callanan , Al Chakra , Sonya Purcell , Hugh Smyth
发明人： Sean Callanan , Al Chakra , Sonya Purcell , Hugh Smyth
IPC分类号： G06F15/16
CPC分类号： G06Q10/107
摘要： In a chat alert method and system, a chat user creates alert profiles that include the requestor's level in an organizational hierarchy as a parameter and the alert type for the level. When a chat client receives a chat request from a requester for a receiver, the chat client determines if there is a chat alert profile that matches the requestor's level. If so, then an alert is issued to the receiver according to the matching chat alert profile. Optionally, the chat alert profile sets an alternate alert system, where if the receiver does not respond to the request within a specified time, an alert is sent using the alternate alert system. Chat requests from requesters higher up in the reporting chain can be highlighted for the receiver. The receiver can then prioritize the chat requests that he/she receives and respond to them in a timely fashion.

4. 发明申请

US20090037538A1 SYSTEM AND METHOD TO PRIORITIZE CHAT ALERTS BASED ON AN ORGANIZATIONAL HIERARCHICAL CHAIN 失效
标题翻译：基于组织层次分析法优化报警系统和方法
公开(公告)号：US20090037538A1
公开(公告)日：2009-02-05
申请号：US11832429
申请日：2007-08-01
申请人： Sean Callanan , Al Chakra , Sonya Purcell , Hugh Smyth
发明人： Sean Callanan , Al Chakra , Sonya Purcell , Hugh Smyth
IPC分类号： G06F15/16
CPC分类号： G06Q10/107
摘要： In a chat alert method and system, a chat user creates alert profiles that include the requestor's level in an organizational hierarchy as a parameter and the alert type for the level. When a chat client receives a chat request from a requester for a receiver, the chat client determines if there is a chat alert profile that matches the requestor's level. If so, then an alert is issued to the receiver according to the matching chat alert profile. Optionally, the chat alert profile sets an alternate alert system, where if the receiver does not respond to the request within a specified time, an alert is sent using the alternate alert system. Chat requests from requesters higher up in the reporting chain can be highlighted for the receiver. The receiver can then prioritize the chat requests that he/she receives and respond to them in a timely fashion.
摘要翻译：在聊天警报方法和系统中，聊天用户创建警报配置文件，其中包括作为参数的组织层次结构中的请求者级别，以及级别的警报类型。当聊天客户端从接收者的请求者接收到聊天请求时，聊天客户端确定是否存在与请求者的级别匹配的聊天警报简档。如果是这样，则根据匹配的聊天警报简档向接收者发出警报。可选地，聊天警报简档设置备用警报系统，其中如果接收器在指定时间内没有响应该请求，则使用备用警报系统发送警报。报告链中更高层的请求者的聊天请求可以为接收者加亮。然后，接收者可以优先处理他/她接收到的聊天请求并及时响应它们。

5. 发明申请

US20080126532A1 BUDDY LIST PRUNING FOR INSTANT MESSAGING SYSTEM PERFORMANCE ENHANCEMENT 有权
标题翻译：用于即时消息传递系统性能增强的布丁列表
公开(公告)号：US20080126532A1
公开(公告)日：2008-05-29
申请号：US11556402
申请日：2006-11-03
申请人： Hugh Smyth , David P. Curley , Patrick O'Sullivan
发明人： Hugh Smyth , David P. Curley , Patrick O'Sullivan
IPC分类号： G06F15/16
CPC分类号： H04L51/04 , G06Q10/107 , H04L12/185
摘要： Embodiments of the present invention address deficiencies of the art in respect to buddy list management for instant messaging systems and provide a novel and non-obvious method, system and computer program product for buddy list pruning for instant messaging system performance enhancement. In one embodiment of the invention, a buddy list pruning method for instant messaging system performance enhancement can include comparing buddy list name entries in a buddy list to entries in a network directory used to authenticate users into a network supporting the instant messaging system. The method further can include characterizing selected ones of the buddy list name entries as either invalid where a buddy list name entry cannot be matched to an entry in the network directory, or as valid where the buddy list name entry can be matched to an entry in the network directory. Finally, the method can include performing presence awareness only on valid buddy list name entries in the buddy list.
摘要翻译：本发明的实施例解决了关于即时消息系统的好友列表管理的本领域的缺点，并提供了一种用于即时消息系统性能增强的好友列表修剪的新颖且非显而易见的方法，系统和计算机程序产品。在本发明的一个实施例中，用于即时消息系统性能增强的好友列表修剪方法可以包括将好友列表中的好友列表名称条目与用于将用户认证到支持即时消息收发系统的网络的网络目录中的条目进行比较。该方法还可以包括将好友列表名称条目中的所选择的一个表示为无效，其中好友列表名称条目不能与网络目录中的条目匹配，或者在伙伴列表名称条目可以匹配到网络目录中的条目网络目录。最后，该方法可以包括仅对好友列表中的有效好友列表名称条目执行存在感知。

6. 发明申请

US20070175472A1 DPI FORMULATION CONTAINING SULFOALKYL ETHER CYCLODEXTRIN 有权
标题翻译：含有硫代环戊二烯的DPI配方
公开(公告)号：US20070175472A1
公开(公告)日：2007-08-02
申请号：US11550976
申请日：2006-10-19
申请人： JAMES PIPKIN , RUPERT ZIMMERER , ANTHONY HICKEY , DIANE THOMPSON , HUGH SMYTH
发明人： JAMES PIPKIN , RUPERT ZIMMERER , ANTHONY HICKEY , DIANE THOMPSON , HUGH SMYTH
IPC分类号： A61M15/00
CPC分类号： A61K47/40 , A61K9/0075 , Y10T428/2982
摘要： An inhalable dry powder formulation containing SAE-CD and an active agent is provided. The formulation is adapted for administration by DPI. The SAE-CD serves as a carrier rather than as an absorption enhancer. The average particle size of the SAE-CD is large enough to preclude (for the most part) pulmonary deposition thereof. Following release from the DPI device, the SAE-CD-containing particles dissociate from the active agent-containing particles in the buccal cavity or throat, after which the active agent-containing particles continue deeper into the respiratory tract. The physicochemical and morphological properties of the SAE-CD are easily modified to permit optimization of active agent and carrier interactions. Drugs having a positive, neutral or negative electrostatic charge can be delivered by DPI when SAE-CD is used as a carrier.
摘要翻译：提供含有SAE-CD和活性剂的可吸入干粉配方。该制剂适用于DPI的给药。 SAE-CD作为载体而不是吸收增强剂。 SAE-CD的平均粒径足够大以排除（大部分）肺沉积。在从DPI装置释放后，含有SAE-CD的颗粒从颊腔或咽喉中的含活性剂颗粒解离，之后含活性剂的颗粒继续深入呼吸道。 SAE-CD的物理化学和形态学特性易于修饰，可以优化活性剂和载体的相互作用。当使用SAE-CD作为载体时，具有正，中性或负静电电荷的药物可由DPI递送。

7. 发明申请

US20070124394A1 METHOD AND APPARATUS FOR PROPAGATING ADDRESS CHANGE IN AN EMAIL 有权
标题翻译：在电子邮件中传播地址更改的方法和装置
公开(公告)号：US20070124394A1
公开(公告)日：2007-05-31
申请号：US11423472
申请日：2006-06-12
申请人： Colm Farrell , David Ogle , Patrick O'Sullivan , Hugh Smyth
发明人： Colm Farrell , David Ogle , Patrick O'Sullivan , Hugh Smyth
IPC分类号： G06F15/16
CPC分类号： H04L51/28 , G06Q10/107 , H04L51/30
摘要： There is provided a system, method and computer program product for managing an email comprising a plurality of email boxes with corresponding email addresses; a first selector for selecting, in one email box, an email that has been sent to at least one addressee; a second selector for selecting an incorrect email address in the sent email corresponding to an incorrect addressee; a change service for changing, in the sent email, the incorrect address to the correct address; and a distributor for making the change service available to at least one recipient box.
摘要翻译：提供了一种用于管理电子邮件的系统，方法和计算机程序产品，其包括具有相应电子邮件地址的多个电子邮箱; 在一个电子邮箱中选择已发送给至少一个收件人的电子邮件的第一选择器; 第二选择器，用于在发送的电子邮件中选择与错误收件人相对应的不正确的电子邮件地址; 更改服务，将发送的电子邮件中的错误地址更改为正确的地址; 以及用于使更改服务可用于至少一个接收方的分发者。

8. 发明申请

US20130012893A1 TOROIDAL PHARMACEUTICAL FORMULATIONS 有权
标题翻译： TOROIDAL PHARMACEUTICAL配方
公开(公告)号：US20130012893A1
公开(公告)日：2013-01-10
申请号：US13535069
申请日：2012-06-27
申请人： Hugh Smyth , Matthew Herpin
发明人： Hugh Smyth , Matthew Herpin
IPC分类号： A61F9/00 , A61P27/02 , A61M35/00 , A61K9/14
CPC分类号： A61K9/0048 , A61K9/12
摘要： There is provided methods for administering a toroidal pharmaceutical composition to a subject. The method includes dispensing a toroidal pharmaceutical composition, and allowing the toroidal pharmaceutical composition to contact a target organ of the subject, thereby administering the toroidal pharmaceutical composition. There are additionally provided toroidal aerosol delivery systems.
摘要翻译：提供了向对象施用环形药物组合物的方法。该方法包括分配环形药物组合物，并允许环形药物组合物接触受试者的靶器官，从而施用环形药物组合物。另外提供环形气溶胶输送系统。

9. 发明申请

US20120291780A1 BEAD-CONTAINING DRY POWDER INHALER 有权
标题翻译：含珠的干粉吸入器
公开(公告)号：US20120291780A1
公开(公告)日：2012-11-22
申请号：US13469963
申请日：2012-05-11
申请人： Martin J. Donovan , Jacques Pappo , Hugh Smyth
发明人： Martin J. Donovan , Jacques Pappo , Hugh Smyth
IPC分类号： A61M15/00
CPC分类号： A61M15/0028 , A61M15/0003 , A61M15/001 , A61M15/0021 , A61M15/0036 , A61M15/0063 , A61M16/127 , A61M2202/064 , A61M2205/43
摘要： A dry powder inhaler includes a chamber holding a bead-like actuator to which a powdered medicament is adhered. Air is drawn into the chamber through an inlet flow channel and exits through an outlet flow channel. The bead-like actuator oscillates in response to the air flow, dislodging powdered medicament to be entrained in the air flow and delivered to the patient.
摘要翻译：干粉吸入器包括容纳粘附有粉末状药物的珠状致动器的腔室。空气通过入口流动通道被吸入室内，并通过出口流动通道离开。珠状致动器响应于空气流动而振荡，将粉末状药物移走以夹带在空气流中并输送到患者体内。

10. 发明授权

US08117302B2 Buddy list pruning for instant messaging system performance enhancement 有权
标题翻译：好友列表修剪即时消息系统性能提升
公开(公告)号：US08117302B2
公开(公告)日：2012-02-14
申请号：US11556402
申请日：2006-11-03
申请人： Hugh Smyth , David P. Curley , Patrick O'Sullivan
发明人： Hugh Smyth , David P. Curley , Patrick O'Sullivan
IPC分类号： G06F15/173
CPC分类号： H04L51/04 , G06Q10/107 , H04L12/185
摘要： A method, system and computer program product for buddy list pruning for instant messaging system performance enhancement. In one embodiment of the invention, a buddy list pruning method for instant messaging system performance enhancement can include comparing buddy list name entries in a buddy list to entries in a network directory used to authenticate users into a network supporting the instant messaging system. The method further can include characterizing selected ones of the buddy list name entries as either invalid where a buddy list name entry cannot be matched to an entry in the network directory, or as valid where the buddy list name entry can be matched to an entry in the network directory. Finally, the method can include performing presence awareness only on valid buddy list name entries in the buddy list.
摘要翻译：用于即时消息系统性能提升的好友列表修剪的方法，系统和计算机程序产品。在本发明的一个实施例中，用于即时消息系统性能增强的好友列表修剪方法可以包括将好友列表中的好友列表名称条目与用于将用户认证到支持即时消息收发系统的网络的网络目录中的条目进行比较。该方法还可以包括将好友列表名称条目中的所选择的一个表示为无效，其中好友列表名称条目不能与网络目录中的条目匹配，或者在伙伴列表名称条目可以匹配到网络目录中的条目网络目录。最后，该方法可以包括仅对好友列表中的有效好友列表名称条目执行存在感知。

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