专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US07799527B2 Systems and methods for automated quality control of polymer synthesis 有权
标题翻译：聚合物合成自动化质量控制的系统和方法
公开(公告)号：US07799527B2
公开(公告)日：2010-09-21
申请号：US11173952
申请日：2005-07-01
申请人： Nels A. Olson , Bahram Ghaffarzadeh Kermani , Hongji Ren , Theo Kotseroglou
发明人： Nels A. Olson , Bahram Ghaffarzadeh Kermani , Hongji Ren , Theo Kotseroglou
IPC分类号： C12Q1/68 , G01N33/53 , C07H21/02 , A61K38/00 , C07K1/00
CPC分类号： C40B99/00 , B01J2219/00693
摘要： The invention provides systems and methods for evaluating synthetic reactions such as polymer synthesis reactions. Evaluation of a synthetic reaction product can be based on a quantitative measure of synthesis such as coupling efficiency or yield, and various parameters determined from a separation record obtained for the synthetic reaction product. The invention further provides methods for evaluating a separation method based on various parameters determined from a separation record. The invention can be used to select an appropriate treatment for a synthetic reaction product such as a separation treatment or treatments related to further processing for the desired product. The methods are particularly useful for automated selection of treatments for synthetic reaction products.
摘要翻译：本发明提供用于评价合成反应如聚合物合成反应的系统和方法。合成反应产物的评估可以基于合成的定量测量，例如偶合效率或产率，以及由合成反应产物获得的分离记录确定的各种参数。本发明还提供了基于从分离记录确定的各种参数来评估分离方法的方法。本发明可用于选择合成反应产物的合适处理，例如分离处理或与所需产物的进一步加工有关的处理。该方法对于自动选择合成反应产物的处理特别有用。

2. 发明申请

US20100157086A1 DYNAMIC AUTOFOCUS METHOD AND SYSTEM FOR ASSAY IMAGER 审中-公开
标题翻译：动态自动方法和系统用于测量图像
公开(公告)号：US20100157086A1
公开(公告)日：2010-06-24
申请号：US12638770
申请日：2009-12-15
申请人： DARREN R. SEGALE , JOHN A. MOON , HONGJI REN
发明人： DARREN R. SEGALE , JOHN A. MOON , HONGJI REN
IPC分类号： H04N5/225 , G06K9/40
CPC分类号： C12Q1/6818 , C12Q1/6874 , G01B9/02063 , G01B11/24 , G01N21/6428 , G01N21/6458 , G02B21/244 , H04N5/23212
摘要： A method and system are provided for controlling focus dynamically of a sample imager. The method comprises scanning a sample with an optical assembly that apportions the sample into regions based on a scan pattern. The optical assembly has a focal setting with respect to the sample. The method further comprises shifting the focal setting of the optical assembly during scanning of the sample, and detecting one or more images representative of one of the regions from the sample. The one or more images have associated degrees of focus corresponding to the focal setting of the optical assembly. The method analyzes the image(s) to obtain a focus score or scores corresponding thereto, where the focus scores represent a degree to which the optical assembly was in focus when detecting the images. The method adjusts the focus setting based on the focus score(s).
摘要翻译：提供了一种方法和系统，用于动态地控制样本成像器的焦点。该方法包括用基于扫描图案将样品分配到区域的光学组件扫描样品。光学组件相对于样品具有聚焦设置。该方法还包括在扫描样品期间移动光学组件的焦点设置，以及从样本中检测代表一个区域的一个或多个图像。一个或多个图像具有与光学组件的焦点设置相对应的相关度的焦点。该方法分析图像以获得对应的焦点得分或分数，其中焦点分数表示在检测图像时光学组件聚焦的程度。该方法根据焦点得分调整焦点设置。

3. 发明申请

US20140079923A1 POLYMER COATINGS 有权
标题翻译：聚合物涂料
公开(公告)号：US20140079923A1
公开(公告)日：2014-03-20
申请号：US13784368
申请日：2013-03-04
申请人： Wayne N. George , Andrew A. Brown , Daniel Bratton , Hongji Ren , Ryan C. Smith
发明人： Wayne N. George , Andrew A. Brown , Daniel Bratton , Hongji Ren , Ryan C. Smith
IPC分类号： C09D135/00
CPC分类号： C12Q1/6874 , B05D3/06 , B05D3/065 , C09D133/26 , C09D135/00 , C12Q1/6806 , Y10T428/24802 , Y10T428/24917 , Y10T428/24926 , Y10T428/2998 , Y10T428/31536 , Y10T428/31935
摘要： The present disclosure relates to polymer coatings covalently attached to the surface of a substrate and the preparation of the polymer coatings, such as poly(N-(5-azidoacetamidylpentyl)acrylamide-co-acrylamide) (PAZAM), in the formation and manipulation of substrates, such as molecular arrays and flow cells. The present disclosure also relates to methods of preparing a substrate surface by using beads coated with a covalently attached polymer, such as PAZAM, and the method of determining a nucleotide sequence of a polynucleotide attached to a substrate surface described herein.
摘要翻译：本公开内容涉及共价连接到基材表面上的聚合物涂层以及聚（N-（5-叠氮基乙酰胺基戊基）丙烯酰胺 - 共 - 丙烯酰胺）聚合物涂层的制备（PAZAM），其形成和操作底物，如分子阵列和流动池。本公开还涉及通过使用涂覆有共价连接的聚合物（例如PAZAM）的珠来制备底物表面的方法，以及测定与本文所述的底物表面连接的多核苷酸的核苷酸序列的方法。

4. 发明申请

US20110105356A1 COMPOSITIONS AND METHODS FOR PROVIDING SUBSTANCES TO AND FROM AN ARRAY 审中-公开
标题翻译：用于向物质提供物质和从阵列提供物质的组合物和方法
公开(公告)号：US20110105356A1
公开(公告)日：2011-05-05
申请号：US12991121
申请日：2009-05-05
申请人： Chad F. DeRosier , John A. Moon , Fiona E. Black , Robert Yang , Hongji Ren , David L. Heiner
发明人： Chad F. DeRosier , John A. Moon , Fiona E. Black , Robert Yang , Hongji Ren , David L. Heiner
IPC分类号： C40B30/04 , C40B50/00 , C40B50/06 , C40B40/00
CPC分类号： C40B50/14 , B01J19/0046 , B01J2219/00317 , B01J2219/00382 , B01J2219/00495 , B01J2219/00527 , B01J2219/00585 , B01J2219/00596 , B01J2219/00605 , B01J2219/00644 , B01J2219/00722 , B01J2219/00725 , B01L3/5085 , B01L2300/0819 , C40B60/14
摘要： Methods, kits, systems, and multilayer transfer media for transferring a substance to and from an array are disclosed herein. Also disclosed herein are methods of detecting a substance that has been transferred to an array.
摘要翻译：本文公开了用于将物质转移到阵列和从阵列转移物质的方法，试剂盒，系统和多层转移介质。本文还公开了检测已经转移到阵列的物质的方法。

5. 发明申请

US20070003941A1 Systems and methods for automated quality control of polymer synthesis 有权
标题翻译：聚合物合成自动化质量控制的系统和方法
公开(公告)号：US20070003941A1
公开(公告)日：2007-01-04
申请号：US11173952
申请日：2005-07-01
申请人： Nels Olson , Bahram Kermani , Hongji Ren , Theo Kotseroglou
发明人： Nels Olson , Bahram Kermani , Hongji Ren , Theo Kotseroglou
IPC分类号： C12Q1/68 , G06F19/00
CPC分类号： C40B99/00 , B01J2219/00693
摘要： The invention provides systems and methods for evaluating synthetic reactions such as polymer synthesis reactions. Evaluation of a synthetic reaction product can be based on a quantitative measure of synthesis such as coupling efficiency or yield, and various parameters determined from a separation record obtained for the synthetic reaction product. The invention further provides methods for evaluating a separation method based on various parameters determined from a separation record. The invention can be used to select an appropriate treatment for a synthetic reaction product such as a separation treatment or treatments related to further processing for the desired product. The methods are particularly useful for automated selection of treatments for synthetic reaction products.
摘要翻译：本发明提供用于评价合成反应如聚合物合成反应的系统和方法。合成反应产物的评估可以基于合成的定量测量，例如偶合效率或产率，以及由合成反应产物获得的分离记录确定的各种参数。本发明还提供了基于从分离记录确定的各种参数来评估分离方法的方法。本发明可用于选择合成反应产物的合适处理，例如分离处理或与所需产物的进一步加工有关的处理。该方法对于自动选择合成反应产物的处理特别有用。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式