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1. 发明授权

US08040431B2 Terminal cover for camera apparatus 失效
标题翻译：相机设备端子盖
公开(公告)号：US08040431B2
公开(公告)日：2011-10-18
申请号：US12317087
申请日：2008-12-18
申请人： Keita Okuda , Hidenori Ishibashi , Hidetoshi Isawa , Tatsuya Yamazaki
发明人： Keita Okuda , Hidenori Ishibashi , Hidetoshi Isawa , Tatsuya Yamazaki
IPC分类号： H04N5/225
CPC分类号： H04N5/2251
摘要： Disclosed is a camera apparatus including an enclosure configured to enclose an imaging unit, a terminal arrangement unit arranged adjacent to a curved surface of an edge portion of the enclosure, and a cover member for covering the terminal arrangement unit, configured to move to open in parallel and along a straight guide groove provided near the terminal arrangement unit, and to turn along the curved surface of the edge portion when the cover has moved to open a prescribed amount along the straight guide groove.
摘要翻译：公开了一种照相机装置，包括被配置为封闭成像单元的外壳，邻近外壳边缘部分的曲面布置的端子排列单元，以及用于覆盖端子排列单元的盖构件，平行并且沿着设置在端子排列单元附近的直线引导槽，并且当盖已经沿着直的引导槽移动到规定量的位置时沿着边缘部分的弯曲表面转动。

2. 发明申请

US20090161007A1 Camera apparatus 失效
标题翻译：相机设备
公开(公告)号：US20090161007A1
公开(公告)日：2009-06-25
申请号：US12317087
申请日：2008-12-18
申请人： Keita Okuda , Hidenori Ishibashi , Hidetoshi Isawa , Tatsuya Yamazaki
发明人： Keita Okuda , Hidenori Ishibashi , Hidetoshi Isawa , Tatsuya Yamazaki
IPC分类号： H04N5/225
CPC分类号： H04N5/2251
摘要： Disclosed is a camera apparatus including an enclosure configured to enclose an imaging unit, a terminal arrangement unit arranged adjacent to a curved surface of an edge portion of the enclosure, and a cover member for covering the terminal arrangement unit, configured to move to open in parallel and along a straight guide groove provided near the terminal arrangement unit, and to turn along the curved surface of the edge portion when the cover has moved to open a prescribed amount along the straight guide groove.
摘要翻译：公开了一种照相机装置，包括被配置为封闭成像单元的外壳，邻近外壳边缘部分的曲面布置的端子排列单元，以及用于覆盖端子排列单元的盖构件，平行并且沿着设置在端子排列单元附近的直线引导槽，并且当盖沿着直线引导槽移动到规定量的位置时沿着边缘部分的弯曲表面转动。

3. 发明申请

US20080136954A1 IMAGE CAPTURE APPARATUS 审中-公开
标题翻译：图像捕捉设备
公开(公告)号：US20080136954A1
公开(公告)日：2008-06-12
申请号：US11774712
申请日：2007-07-09
申请人： Shogo Kato , Nobutatsu Takahashi , Hidetoshi Isawa
发明人： Shogo Kato , Nobutatsu Takahashi , Hidetoshi Isawa
IPC分类号： H04N5/225 , G03B17/02
CPC分类号： G03B17/02 , H04N5/2251
摘要： A panel housing moves across a storage position and first and second usage position. In the storage position, the panel housing closes against a housing body and a display surface is positioned in close proximity to a storage face of the housing body. In the first usage position, the panel housing opens to thereby cause the display surface to be visible. In the second usage position, the panel housing closes, and an outer face of the panel housing is positioned close proximity to the storage face to thereby cause the display surface to be visible. The storage face has a protrusion for stopping rotation of the panel housing about a second axis when either an inner face of the panel housing or the display surface is pushed toward the outer face in the state that the panel housing positioned in the second usage position.
摘要翻译：面板壳体在存储位置和第一和第二使用位置移动。在存储位置中，面板壳体抵靠壳体主体并且显示表面定位成紧邻壳体的存储面。在第一使用位置，面板壳体打开，从而使显示表面可见。在第二使用位置，面板壳体闭合，并且面板壳体的外表面定位成紧密靠近存储面，从而使显示表面可见。当在面板壳体位于第二使用位置的状态下，当面板壳体的内表面或显示表面被推向外表面时，存储面具有用于停止面板壳体绕第二轴旋转的突起。

4. 发明授权

US07208520B2 Crystals of hydroxynorephedrine derivative 失效
标题翻译：羟基麻黄碱衍生物的晶体
公开(公告)号：US07208520B2
公开(公告)日：2007-04-24
申请号：US10489343
申请日：2002-08-27
申请人： Hidetoshi Isawa , Yukihiko Hotei , Kiyoshi Kasai , Junichi Sonehara , Satoshi Akahane , Hiromu Harada
发明人： Hidetoshi Isawa , Yukihiko Hotei , Kiyoshi Kasai , Junichi Sonehara , Satoshi Akahane , Hiromu Harada
IPC分类号： A01N37/12 , A01N37/44 , A61K31/24
CPC分类号： A61K31/216 , C07B2200/07 , C07C217/60
摘要： The present invention provides ethyl (−)-2-[4-[2-[[(1S,2R)-2-hydroxy-2-(4-hydroxyphenyl)-1-methylethyl]amino]ethyl]-2,5-dimethylphenoxy]acetate hydrochloride, crystalline forms thereof and pharmaceutical compositions containing them, which have excellent β3-adrenoceptor stimulating effects, therapeutic effects on pollakiuria or urinary incontinence and storage stabilities and are useful as a medicament.
摘要翻译：本发明提供了（ - ） - 2- [4- [2 - [[（1S，2R）-2-羟基-2-（4-羟基苯基）-1-甲基乙基]氨基]乙基] 二甲基苯氧基]乙酸盐酸盐，其结晶形式和含有它们的药物组合物，其具有优异的β3 - 肾上腺素受体刺激作用，对尿频尿失禁和储尿稳定性的治疗作用，并且可用作药物。

5. 发明申请

US20160129031A1 PYRAZOLE DERIVATIVE AND USE THEREOF FOR MEDICAL PURPOSES 有权
公开(公告)号：US20160129031A1
公开(公告)日：2016-05-12
申请号：US14995489
申请日：2016-01-14
申请人： Masayuki Isaji , Masaaki Takemura , Hidetoshi Isawa , Yukihiko Hotei , Itaru Miyashita
发明人： Masayuki Isaji , Masaaki Takemura , Hidetoshi Isawa , Yukihiko Hotei , Itaru Miyashita
IPC分类号： A61K31/7056
CPC分类号： A61K31/7056 , C07H17/02
摘要： The present invention provides pyrazole derivatives, uses thereof for medical purposes and so on. More particularly, the present invention relates to pharmaceuticals useful for the prevention or treatment of constipation, which comprise as an active ingredient 3-(3-{4-[3-(β-D-glucopyranosyloxy)-5-isopropyl-1H-pyrazol-4-ylmethyl]-3-methylphenoxy}propylamino)-2,2-dimethylpropionamide, or a pharmaceutically acceptable salt thereof. The pharmaceuticals of the present invention exert an effect of increasing the frequency of bowel movement or the like, and are useful for the prevention or treatment of constipation.

6. 发明授权

US08023039B2 Image capture apparatus with an operation member for a cover of a connector 失效
标题翻译：具有用于连接器的盖的操作构件的图像捕获装置
公开(公告)号：US08023039B2
公开(公告)日：2011-09-20
申请号：US11774715
申请日：2007-07-09
申请人： Tomoyuki Mito , Nobutatsu Takahashi , Hidetoshi Isawa
发明人： Tomoyuki Mito , Nobutatsu Takahashi , Hidetoshi Isawa
IPC分类号： H04N5/225
CPC分类号： G03B17/02 , H04N5/2251
摘要： An image capture apparatus includes a housing body, an image capture optical system, an image capture device, a connector, a cover, and an operation member. The display panel is provided to the housing body to be pivotable between a usage position where a display surface of the display panel is visible and a storage position where the display surface of the display panel is in contact with a surface of the housing body. The cover opens or closes the insertion/removal opening by extending or retracting on the insertion/removal opening from an interior of the housing body. The operation member is provided to the housing body, and is operated to move the cover along a direction of opening or closing the insertion/removal opening, the operation member being provided to the housing body.
摘要翻译：图像捕获装置包括壳体，图像捕获光学系统，图像捕获装置，连接器，盖和操作构件。显示面板设置在壳体上，可在可见显示面板的显示面的使用位置与显示面板的显示面与壳体的表面接触的存放位置之间转动。盖通过从壳体的内部在插入/取出开口上伸出或缩回来打开或关闭插入/取出开口。操作构件设置在壳体上，并且操作以沿着打开或关闭插入/取出开口的方向移动盖，操作构件设置在壳体上。

7. 发明授权

US08022192B2 Process for production of glucopyranosyloxypyrazole derivative 有权
标题翻译：吡喃葡萄糖氧吡唑衍生物的制备方法
公开(公告)号：US08022192B2
公开(公告)日：2011-09-20
申请号：US11908693
申请日：2006-03-16
申请人： Kiyoshi Kasai , Tetsuji Ozawa , Nobuhiko Fushimi , Hidetoshi Isawa , Ken Kikuchi , Masahiro Kobayashi , Junichi Sonehara , Minoru Kubota
发明人： Kiyoshi Kasai , Tetsuji Ozawa , Nobuhiko Fushimi , Hidetoshi Isawa , Ken Kikuchi , Masahiro Kobayashi , Junichi Sonehara , Minoru Kubota
IPC分类号： C07H17/02 , A61K31/7056
CPC分类号： C07H17/02
摘要： The present invention relates to a method for preparing the glucopyranosyloxypyrazole derivatives which are useful as agents for the prevention or treatment of a disease associated with hyperglycemia such as diabetes, diabetic complications, obesity or the like. A glucopyranosyloxypyrazole derivative can be easily and efficiently prepared by allowing a benzylpyrazole derivative represented by the general formula: wherein R1, R2, R3, R4 and R5 may be the same or different, for example each of them is a hydrogen atom, a halogen atom or an alkyl, alkoxy, arylmethyloxy group or the like, R6 is an alkyl group, for example R7 is a hydrogen atom or an alkyl, alkoxy, arylmethyloxy group or the like, to react with a compound represented by the general formula: wherein as an example, PG1 is a pivaloyl group or the like, as an example, X1 is a bromine atom or the like, therefore the present invention is extremely useful as a method for preparing pharmaceutical compounds.
摘要翻译：本发明涉及一种制备吡喃葡萄糖氧吡唑衍生物的方法，其可用作预防或治疗与糖尿病，糖尿病并发症，肥胖症等高血糖相关的疾病的药剂。吡喃葡萄糖氧吡唑衍生物可以容易且有效地制备，其中R 1，R 2，R 3，R 4和R 5可以相同或不同，例如氢原子，卤原子或烷基，烷氧基，芳基甲氧基等，R6是烷基，例如R7是氢原子或烷基，烷氧基，芳基甲氧基等，与通式表示的化合物反应：其中作为作为实例，PG1是新戊酰基等，作为实例，X1是溴原子等，因此本发明作为制备药物化合物的方法是非常有用的。

8. 发明授权

US08003694B2 Crystal of hydroxynorephedrin derivative hydrochloride ¼ hydrate 失效
标题翻译：羟基去甲基卟啉衍生物盐酸盐水合物晶体
公开(公告)号：US08003694B2
公开(公告)日：2011-08-23
申请号：US11912420
申请日：2006-04-24
申请人： Hidetoshi Isawa , Michio Toda
发明人： Hidetoshi Isawa , Michio Toda
IPC分类号： A61K31/24 , C07C229/38
CPC分类号： C07C217/60
摘要： The present invention provides ethyl (−)-2-[4-[2-[[1S,2R]-2-hydroxy-2-(4-hydroxyphenyl)-1-methylethyl]amino]ethyl]-2,5-dimethylphenoxyacetate hydrochloride ¼ hydrate or a crystal thereof which can be determined by characteristic diffraction peaks of the powder X-ray diffraction, thermogravimetry-differential thermal analysis or the like, and obtained by manufacturing ethyl (−)-2-[4-[2-[[1S,2R]-2-hydroxy-2-(4-hydroxyphenyl)-1-methyl-ethyl]amino]ethyl]-2,5-dimethylphenoxyacetate by a specific method.
摘要翻译：本发明提供（ - ） - 2- [4- [2 - [[1S，2R] -2-羟基-2-（4-羟基苯基）-1-甲基乙基]氨基]乙基] -2,5-二甲基苯氧基乙酸乙酯可以通过粉末X射线衍射，热重分析 - 差示热分析等的特征衍射峰确定，并通过制备（ - ） - 2- [4- [2- [ [1S，2R] -2-羟基-2-（4-羟基苯基）-1-甲基 - 乙基]氨基]乙基] -2,5-二甲基苯氧基乙酸乙酯。

9. 发明授权

US5624948A 1-(2-benzimidazolyl)-1,5-diazacyclooctane compounds 失效
标题翻译： 1-（2-苯并咪唑基）-1,5-二氮杂环辛烷化合物
公开(公告)号：US5624948A
公开(公告)日：1997-04-29
申请号：US537747
申请日：1995-11-14
申请人： Hidetoshi Isawa , Nobuko Yanagi , Yasuo Takehana , Den-ichi Momose , Masaaki Satoh , Yoshinori Nonaka
发明人： Hidetoshi Isawa , Nobuko Yanagi , Yasuo Takehana , Den-ichi Momose , Masaaki Satoh , Yoshinori Nonaka
IPC分类号： C07D235/30 , C07D403/04 , A61K31/415
CPC分类号： C07D403/04 , C07D235/30
摘要： 1-(2-benzimidazolyl)-1,5-diazacyclooctane compounds represented by the formula: ##STR1## wherein X represents a hydrogen atom or a halogen atom; Y represents a covalent bond, a straight- or branched-chain alkylene group having 1 to 6 carbon atoms, or a straight- or branched-chain alkenylene group having 2 to 6 carbon atoms; R represents a hydrogen atom, or a straight- or branched-chain alkyl group having 1 to 6 carbon atoms; and pharmaceutically acceptable salts thereof. The compounds represented above are novel potent and long-lasting histamine HI-receptor antagonist with less-topical irritation, and can be topically administered by inhalation for the treatment of bronchial asthma.
摘要翻译： PCT No.PCT / JP94 / 00787 Sec。 371日期：1995年11月14日 102（e）日期1995年11月14日PCT 1994年5月16日PCT公布。第WO94 / 27973号公报日期：1994年12月8日1-（2-苯并咪唑基）-1,5-二氮杂环辛烷化合物，由下式表示：其中X表示氢原子或卤原子; Y表示共价键，具有1〜6个碳原子的直链或支链亚烷基或具有2〜6个碳原子的直链或支链亚烯基; R表示氢原子，或具有1〜6个碳原子的直链或支链烷基; 及其药学上可接受的盐。上述化合物是具有较少局部刺激性的新型有效和持久的组胺HI受体拮抗剂，并且可以通过吸入局部施用以治疗支气管哮喘。

10. 发明申请

US20090062518A1 PROCESS FOR PRODUCTION OF GLUCOPYRANOSYLOXYPYRAZOLE DERIVATIVE 有权
标题翻译：生产葡萄糖酰氧基吡唑衍生物的方法
公开(公告)号：US20090062518A1
公开(公告)日：2009-03-05
申请号：US11908693
申请日：2006-03-16
申请人： Kiyoshi Kasai , Tetsuji Ozawa , Nobuhiko Fushimi , Hidetoshi Isawa , Ken Kikuchi , Masahiro Kobayashi , Junichi Sonehara , Minoru Kubota
发明人： Kiyoshi Kasai , Tetsuji Ozawa , Nobuhiko Fushimi , Hidetoshi Isawa , Ken Kikuchi , Masahiro Kobayashi , Junichi Sonehara , Minoru Kubota
IPC分类号： C07H1/00
CPC分类号： C07H17/02
摘要： The present invention relates to a method for preparing the glucopyranosyloxypyrazole derivatives which are useful as agents for the prevention or treatment of a disease associated with hyperglycemia such as diabetes, diabetic complications, obesity or the like.A glucopyranosyloxypyrazole derivative can be easily and efficiently prepared by allowing a benzylpyrazole derivative represented by the general formula: wherein R1, R2, R3, R4 and R5 may be the same or different, for example each of them is a hydrogen atom, a halogen atom or an alkyl, alkoxy, arylmethyloxy group or the like, R6 is an alkyl group, for example R7 is a hydrogen atom or an alkyl, alkoxy, arylmethyloxy group or the like, to react with a compound represented by the general formula: wherein as an example, PG1 is a pivaloyl group or the like, as an example, X1 is a bromine atom or the like, therefore the present invention is extremely useful as a method for preparing pharmaceutical compounds.
摘要翻译：本发明涉及一种制备吡喃葡萄糖氧吡唑衍生物的方法，其可用作预防或治疗与糖尿病，糖尿病并发症，肥胖症等高血糖相关的疾病的药剂。吡喃葡萄糖氧吡唑衍生物可以容易且有效地制备，其中R 1，R 2，R 3，R 4和R 5可以相同或不同，例如氢原子，卤原子或烷基，烷氧基，芳基甲氧基等，R6是烷基，例如R7是氢原子或烷基，烷氧基，芳基甲氧基等，与通式表示的化合物反应：其中作为作为实例，PG1是新戊酰基等，作为实例，X1是溴原子等，因此本发明作为制备药物化合物的方法是非常有用的。

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