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1. 发明申请

US20100299767A1 TREM-2 GENE AND PROTEIN AS INHIBITORS OF EXPRESSION OF GA733-2, AND TRANSGENIC ANIMALS COMPRISING THE SAME AND USES THEREOF 失效
标题翻译：作为GA733-2表达的抑制剂的TREM-2基因和蛋白质以及包含其的转基因动物及其用途
公开(公告)号：US20100299767A1
公开(公告)日：2010-11-25
申请号：US12863548
申请日：2009-02-18
申请人： Hyung-Sik Kang , Eun-Mi Kim , Dong-Hern Kim , Ha-Rim Choi , Eun-Hee Lee , Il-Soo Kim , Chang-Eon Park
发明人： Hyung-Sik Kang , Eun-Mi Kim , Dong-Hern Kim , Ha-Rim Choi , Eun-Hee Lee , Il-Soo Kim , Chang-Eon Park
IPC分类号： A61K49/00 , A01K67/00 , C12Q1/68 , G01N33/574 , A61K31/711 , A61K38/16 , A61P35/00
CPC分类号： C07K14/705 , A01K67/0275 , A01K2217/052 , A01K2227/105 , A01K2267/0331 , A61K48/00 , C12N15/8509
摘要： Disclosed are a composition for inhibiting the expression of GA733-2 or for detecting GA733-2, which comprises TREM-2 gene or protein, a transgenic animal containing same, and a method using the same.
摘要翻译：公开了抑制GA733-2的表达或检测GA733-2的组合物，其包含TREM-2基因或蛋白质，含有它们的转基因动物及其使用方法。

2. 发明授权

US08557585B2 Fusion polynucleotide for biosynthesis of beta-carotene using bicistronic gene expression and method for producing beta-carotene using the same 有权
标题翻译：使用双顺反子基因表达生物合成β-胡萝卜素的融合多核苷酸和使用其的β-胡萝卜素生产方法
公开(公告)号：US08557585B2
公开(公告)日：2013-10-15
申请号：US12675240
申请日：2008-08-29
申请人： Sun Hwa Ha , Ju Kon Kim , Ha Rin Jung , Jung Bong Kim , Young Mi Kim , Seok-Cheol Suh , Liang Ying Shi , Soon Jong Kweon , Dong Hern Kim
发明人： Sun Hwa Ha , Ju Kon Kim , Ha Rin Jung , Jung Bong Kim , Young Mi Kim , Seok-Cheol Suh , Liang Ying Shi , Soon Jong Kweon , Dong Hern Kim
IPC分类号： C12N15/82 , C12N15/10 , C12N1/20 , A01H15/00
CPC分类号： C12P23/00 , C12N9/00 , C12N9/0083 , C12N9/1085 , C12N15/8216 , C12N15/825
摘要： The present invention relates to fusion polynucleotides for biosynthesis of beta-carotene and a method for producing beta-carotene using the same. More particularly, it relates to fusion polynucleotides encoding phytoene synthase, connective sequences of FMDV-derived 2A sequence or internal ribosome entry site (IRES) and carotene desaturase, and a method for producing beta-carotenes using the same. Fusion polynucleotides and the recombinant vector using the same of the present invention have the effect of expression both phytoene synthase gene and carotene desaturase gene stably within cell transformants. Accordingly, fusion polynucleotides of the present invention can be used to regulate the biosynthetic metabolism of plant producing beta-carotene. Furthermore, it can be applied to effectively increase the content of beta-carotene, a useful metabolite.
摘要翻译：本发明涉及用于β-胡萝卜素生物合成的融合多核苷酸和使用其的β-胡萝卜素生产方法。更具体地，涉及编码芸苔素合酶的融合多核苷酸，FMDV衍生的2A序列或内部核糖体进入位点（IRES）的连接序列和胡萝卜素去饱和酶，以及使用其的β-胡萝卜素的制备方法。融合多核苷酸和使用本发明相同的重组载体具有在细胞转化体内稳定表达八氢番茄红素合成酶基因和胡萝卜素去饱和酶基因的作用。因此，本发明的融合多核苷酸可用于调节产生β-胡萝卜素的植物的生物合成代谢。此外，它可以应用于有效增加β-胡萝卜素的含量，一种有用的代谢物。

3. 发明申请

US20100299783A1 FUSION POLYNUCLEOTIDE FOR BIOSYNTHESIS OF BETA-CAROTENE USING BICISTRONIC GENE EXPRESSION AND METHOD FOR PRODUCING BETA-CAROTENE USING THE SAME 有权
标题翻译：用于使用双歧杆菌基因表达的贝他卡那霉素的生物合成的熔融聚合物和使用它的生产卡培尔的方法
公开(公告)号：US20100299783A1
公开(公告)日：2010-11-25
申请号：US12675240
申请日：2008-08-29
申请人： Sun Hwa Ha , Ju Kon Kim , Ha Rin Jung , Jung Bong Kim , Young Mi Kim , Seok-Cheol Suh , Liang Ying Shi , Soon Jong Kweon , Dong Hern Kim
发明人： Sun Hwa Ha , Ju Kon Kim , Ha Rin Jung , Jung Bong Kim , Young Mi Kim , Seok-Cheol Suh , Liang Ying Shi , Soon Jong Kweon , Dong Hern Kim
IPC分类号： A01H1/00 , C12P5/00 , C12N5/10 , C12N15/63 , C07H21/04 , A01H15/00 , A01H5/00
CPC分类号： C12P23/00 , C12N9/00 , C12N9/0083 , C12N9/1085 , C12N15/8216 , C12N15/825
摘要： The present invention relates to fusion polynucleotides for biosynthesis of beta-carotene and a method for producing beta-carotene using the same. More particularly, it relates to fusion polynucleotides encoding phytoene synthase, connective sequences of FMDV-derived 2A sequence or internal ribosome entry site (IRES) and carotene desaturase, and a method for producing beta-carotenes using the same. Fusion polynucleotides and the recombinant vector using the same of the present invention have the effect of expression both phytoene synthase gene and carotene desaturase gene stably within cell transformants. Accordingly, fusion polynucleotides of the present invention can be used to regulate the biosynthetic metabolism of plant producing beta-carotene. Furthermore, it can be applied to effectively increase the content of beta-carotene, a useful metabolite.
摘要翻译：本发明涉及用于β-胡萝卜素生物合成的融合多核苷酸和使用其的β-胡萝卜素生产方法。更具体地，涉及编码芸苔素合酶的融合多核苷酸，FMDV衍生的2A序列或内部核糖体进入位点（IRES）的连接序列和胡萝卜素去饱和酶，以及使用其的β-胡萝卜素的制备方法。融合多核苷酸和使用本发明相同的重组载体具有在细胞转化体内稳定表达八氢番茄红素合成酶基因和胡萝卜素去饱和酶基因的作用。因此，本发明的融合多核苷酸可用于调节产生β-胡萝卜素的植物的生物合成代谢。此外，它可以应用于有效增加β-胡萝卜素的含量，一种有用的代谢物。

4. 发明申请

US20120131697A1 GENE ENCODING AUXIN RECEPTOR PROTEIN DERIVED FROM RICE AND USE THEREOF 审中-公开
标题翻译：基因编码来自大米和其使用的AUXIN受体蛋白
公开(公告)号：US20120131697A1
公开(公告)日：2012-05-24
申请号：US12935483
申请日：2010-07-21
申请人： Dong Hern Kim , Keun Pyo Lee , Myong Il Kim , Yu Jin Kwon , Yong Sam Kim
发明人： Dong Hern Kim , Keun Pyo Lee , Myong Il Kim , Yu Jin Kwon , Yong Sam Kim
IPC分类号： A01H5/00 , C12N15/29 , C12N15/63 , C12N5/10 , A01H5/10 , C12N1/21 , C12N1/19 , C07K14/415 , A01H1/06
CPC分类号： C07K14/415 , C12N15/8294
摘要： The present invention pertains to an auxin receptor protein involved in activation of proton pump in plasma membrane of a plant derived from rice, a gene encoding the protein, a recombinant vector comprising the gene, a host cell transformed with the recombinant vector, a method of improving traits of a plant by transforming the plant with the recombinant plant expression vector, a plant having improved traits by transformation with the recombinant plant expression vector and seeds of the plant, and a composition comprising the gene of the invention for improving traits of a plant.
摘要翻译：本发明涉及涉及源自水稻的植物的质膜的质子泵活化的生长素受体蛋白质，编码该蛋白质的基因，包含该基因的重组载体，用重组载体转化的宿主细胞，通过用重组植物表达载体转化植物来改善植物的性状，通过用重组植物表达载体和植物种子转化具有改良性状的植物，以及包含本发明基因以改善植物性状的组合物。

5. 发明申请

US20050116667A1 Tile lighting methods and systems 有权
标题翻译：瓷砖照明方法和系统
公开(公告)号：US20050116667A1
公开(公告)日：2005-06-02
申请号：US10828933
申请日：2004-04-21
申请人： George Mueller , Ihor Lys , Frederick Morgan , Colin Piepgras , Brian Roberge , Hern Kim , Kevin Dowling , Derek Logan , Charles Cella
发明人： George Mueller , Ihor Lys , Frederick Morgan , Colin Piepgras , Brian Roberge , Hern Kim , Kevin Dowling , Derek Logan , Charles Cella
IPC分类号： A47B23/06 , E04F13/08 , E04F15/02 , F21K99/00 , F21V21/002 , F21V23/04 , F21V23/06 , F21V33/00 , G09F19/22 , H05B37/02
CPC分类号： F21V33/006 , E04F13/08 , E04F15/02 , E04F2290/026 , F21K9/68 , F21S8/032 , F21S8/033 , F21S8/04 , F21V21/002 , F21V23/0442 , F21V23/06 , F21W2121/02 , F21W2131/401 , F21Y2113/13 , F21Y2115/10 , G09F9/3026 , G09F19/22 , H05B33/0803 , H05B33/0857 , H05B37/0245 , H05B37/029 , Y10S345/903
摘要： A tile lighting system is provided in which an interior space of a tile is lit by LEDs, such as in a grid or edge-lit formation, and a light diffusing panel is disposed over the interior space. The tile lighting system can be combined with others to tile any surface, such as a floor, ceiling, wall, or building exterior. Lighting control signals can be supplied to generate a wide range of effects on the tile lighting units, including effects coordinated among different tile lighting units. Two- and three-dimensional embodiments are contemplated.
摘要翻译：提供了一种瓦片照明系统，其中瓦片的内部空间由诸如格栅或边缘照明地层的LED照亮，并且光漫射板设置在内部空间上。瓦片照明系统可以与其他照明系统结合，以便平铺任何表面，如地板，天花板，墙壁或建筑物外部。可以提供照明控制信号以产生对瓦片照明单元的广泛的效果，包括在不同瓦片照明单元之间协调的效果。考虑了二维和三维实施例。

6. 发明授权

US08263822B2 TREM-2 gene and protein as inhibitors of expression of GA733-2, and transgenic animals comprising the same and uses thereof 失效
标题翻译： TREM-2基因和蛋白质作为GA733-2表达的抑制剂，以及包含其的转基因动物及其用途
公开(公告)号：US08263822B2
公开(公告)日：2012-09-11
申请号：US12863548
申请日：2009-02-18
申请人： Hyung-Sik Kang , Eun-Mi Kim , Dong-Hern Kim , Ha-Rim Choi , Eun-Hee Lee , Il-Soo Kim , Chang-Eon Park
发明人： Hyung-Sik Kang , Eun-Mi Kim , Dong-Hern Kim , Ha-Rim Choi , Eun-Hee Lee , Il-Soo Kim , Chang-Eon Park
IPC分类号： A01K67/00 , A01K67/027 , A01K67/033 , G01N33/00
CPC分类号： C07K14/705 , A01K67/0275 , A01K2217/052 , A01K2227/105 , A01K2267/0331 , A61K48/00 , C12N15/8509
摘要： Disclosed are a composition for inhibiting the expression of GA733-2 or for detecting GA733-2, which comprises TREM-2 gene or protein, a transgenic animal containing same, and a method using the same.
摘要翻译：公开了抑制GA733-2的表达或检测GA733-2的组合物，其包含TREM-2基因或蛋白质，含有它们的转基因动物及其使用方法。

7. 发明申请

US20090113881A1 WET TYPE SCRUBBER FOR EXHAUST GAS AND METHOD OF OPERATION 审中-公开
标题翻译：用于排气的湿式喷枪和操作方法
公开(公告)号：US20090113881A1
公开(公告)日：2009-05-07
申请号：US11864833
申请日：2007-09-28
申请人： In Seob Lee , Hern Kim , Mi Hye Yang
发明人： In Seob Lee , Hern Kim , Mi Hye Yang
IPC分类号： F01N3/04
CPC分类号： B01D53/78 , B01D53/504 , B01D2251/30 , B01D2251/40 , B01D2257/2045 , B01D2257/302 , B01D2257/404
摘要： A wet type scrubber for exhaust gas includes a wet scrubbing chamber which is disposed such that the exhaust gas introduced through an inlet flows horizontally toward an outlet and includes an overflow opening formed at a position in a side surface thereof spaced apart by a certain distance upwardly from the bottom thereof an eliminator which is disposed within the wet scrubbing chamber and installed such that the bottom thereof is positioned below the overflow opening, and includes a plurality of bent blades arranged to form a passage for the exhaust gas; an oil/water separation tank for scrubbing liquid received from the overflow opening by sequentially passing the liquid through a plurality of reservoirs, and a spray nozzle installed to spray the liquid into an inlet-side space of the wet scrubbing chamber.
摘要翻译：用于废气的湿式洗涤器包括湿洗涤室，其被布置成使得通过入口引入的废气水平地朝向出口流动，并且包括形成在其侧表面中的一定距离向上间隔开的位置的溢流开口从底部排出设置在湿式洗涤室内并且安装成使得其底部位于溢流开口下方的消除器，并且包括布置成形成排气通道的多个弯曲刀片; 一个油/水分离罐，用于通过使液体顺序地通过多个储存器来从溢流口洗涤液体;以及喷雾喷嘴，其将液体喷射到湿式洗涤室的入口侧空间中。

8. 发明授权

US07358929B2 Tile lighting methods and systems 有权
标题翻译：瓷砖照明方法和系统
公开(公告)号：US07358929B2
公开(公告)日：2008-04-15
申请号：US10828933
申请日：2004-04-21
申请人： George G. Mueller , Ihor A. Lys , Frederick M. Morgan , Colin Piepgras , Brian Roberge , Hern Kim , Kevin J. Dowling , Derek Logan , Charles H. Cella
发明人： George G. Mueller , Ihor A. Lys , Frederick M. Morgan , Colin Piepgras , Brian Roberge , Hern Kim , Kevin J. Dowling , Derek Logan , Charles H. Cella
IPC分类号： G09G5/00
CPC分类号： F21V33/006 , E04F13/08 , E04F15/02 , E04F2290/026 , F21K9/68 , F21S8/032 , F21S8/033 , F21S8/04 , F21V21/002 , F21V23/0442 , F21V23/06 , F21W2121/02 , F21W2131/401 , F21Y2113/13 , F21Y2115/10 , G09F9/3026 , G09F19/22 , H05B33/0803 , H05B33/0857 , H05B37/0245 , H05B37/029 , Y10S345/903
摘要： A tile lighting system is provided in which an interior space of a tile is lit by LEDs, such as in a grid or edge-lit formation, and a light diffusing panel is disposed over the interior space. The tile lighting system can be combined with others to tile any surface, such as a floor, ceiling, wall, or building exterior. Lighting control signals can be supplied to generate a wide range of effects on the tile lighting units, including effects coordinated among different tile lighting units. Two- and three-dimensional embodiments are contemplated.
摘要翻译：提供了一种瓦片照明系统，其中瓦片的内部空间由诸如格栅或边缘照明地层的LED照亮，并且光漫射板设置在内部空间上。瓦片照明系统可以与其他照明系统结合，以便平铺任何表面，如地板，天花板，墙壁或建筑物外部。可以提供照明控制信号以产生对瓦片照明单元的广泛的效果，包括在不同瓦片照明单元之间协调的效果。考虑了二维和三维实施例。

9. 发明授权

US07033596B1 Transformant for screening of inhibitors for human immunodeficiency virus 失效
标题翻译：用于筛选人类免疫缺陷病毒抑制剂的转化体
公开(公告)号：US07033596B1
公开(公告)日：2006-04-25
申请号：US10009118
申请日：2000-10-18
申请人： Hyuk-Jun Nam , Sang-Hern Kim
发明人： Hyuk-Jun Nam , Sang-Hern Kim
IPC分类号： A61K39/21
CPC分类号： C07K14/005 , C12N2740/16222 , C12Q1/18 , C12Q1/6897 , C12Q1/703
摘要： A microorganism cotransformed with a gene expressing HIV nucleocapsid protein and a plasmid vector containing HIV ψ gene and β-galactosidase reporter gene, and a method for screening HIV inhibitors employing the transformant. The invented method comprising the steps of culturing the transformant, treating it with putative compounds or compositions of HIV inhibitors, and measuring the degree of change in β-galactosidase expression in the culture, can be practically applied in screening HIV packaging inhibitors by which the interaction between HIV nucleocapsid and HIV ψ sequence is blocked.
摘要翻译：用表达HIV核衣壳蛋白的基因和含有HIV-psi基因和β-半乳糖苷酶报告基因的质粒载体共转化的微生物，以及使用转化体筛选HIV抑制剂的方法。本发明的方法包括以下步骤：培养转化体，用推定的化合物或HIV抑制剂的组合物进行处理，并测量培养物中β-半乳糖苷酶表达的变化程度，可实际应用于筛选HIV包装抑制剂 HIV核衣壳和HIV psi序列之间被阻断。

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