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1. 发明申请

US20120112658A1 COLOR TEMPERATURE CONTROL OF FLASH UNITS 审中-公开
标题翻译：闪光灯的颜色温度控制
公开(公告)号：US20120112658A1
公开(公告)日：2012-05-10
申请号：US12676980
申请日：2008-09-09
申请人： Hans-Peter Hauser , Marcel Griessmann , Martin Buser , Urs Zeltner
发明人： Hans-Peter Hauser , Marcel Griessmann , Martin Buser , Urs Zeltner
IPC分类号： H05B37/02
摘要： A flash unit (1) with a flash generator (20) with at least one energy store (21) and at least two luminaire channels and with at least two flash tubes (11, 12, 13), wherein the flash tubes (11, 12, 13) are supplied with energy by the energy store (21) via the luminaire channels, with an energy quantity control apparatus (14), by means of which any desired quantity of energy from the minimum charge up to the maximum charge of the at least one energy store (21) can be provided for each luminaire channel, and with a colour temperature control apparatus (15), by means of which a coloured temperature can be set for each luminaire channel independently of the quantity of energy provided therefor, and a corresponding method therefor.
摘要翻译：一种具有闪光发生器（20）的闪光单元（1），具有至少一个能量存储器（21）和至少两个照明器通道以及至少两个闪光管（11,12,13），其中闪光灯管（11， 12）由能量储存器（21）通过灯具通道与能量控制装置（14）一起被供能，通过该能量控制装置，从最小充电到最大充电的任何所需量的能量可以为每个灯具通道提供至少一个能量存储器（21），并且可以使用色温控制设备（15），通过该色温控制设备可以独立于为其提供的能量的量而为每个灯具通道设置着色温度，及其相应的方法。

2. 发明申请

US20090175893A1 Albumin-Fused Anti-Angiogenesis Peptides 审中-公开
标题翻译：白蛋白融合抗血管生成肽
公开(公告)号：US20090175893A1
公开(公告)日：2009-07-09
申请号：US12358815
申请日：2009-01-23
申请人： Peter Mertins , Ilhan Celik , Oliver Kisker , Darrell Sleep , Joanna Hay , Hans-Peter Hauser
发明人： Peter Mertins , Ilhan Celik , Oliver Kisker , Darrell Sleep , Joanna Hay , Hans-Peter Hauser
IPC分类号： A61K39/00 , A61K38/16
CPC分类号： A61K38/39 , A01K2217/05 , A61K9/0019 , A61K31/7088 , A61K38/00 , A61K39/00 , A61K39/0005 , A61K47/643 , A61K48/00 , A61K2039/53 , C07K14/005 , C07K14/47 , C07K14/765 , C07K14/78 , C07K14/8114 , C07K2319/00 , C07K2319/31 , C12N15/62 , C12N2740/16122 , C12Y301/26003
摘要： The invention relates to proteins comprising angiogenesis inhibiting peptides, such as endostatin peptides (including, but not limited to, fragments and variants thereof), which exhibit anti-retroviral activity, fused or conjugated to albumin (including, but not limited to fragments or variants of albumin). These fusion proteins are herein collectively referred to as “albumin fusion proteins of the invention.” These fusion proteins are herein collectively referred to as “albumin fusion proteins of the invention.” These fusion proteins exhibit extended shelf-life and/or extended or therapeutic activity in solution. The invention encompasses therapeutic albumin fusion proteins, compositions, pharmaceutical compositions, formulations and kits. The invention also encompasses nucleic acid molecules encoding the albumin fusion proteins of the invention, as well as vectors containing these nucleic acids, host cells transformed with these nucleic acids and vectors, and methods of making the albumin fusion proteins of the invention using these nucleic acids, vectors, and/or host cells. The invention also relates to compositions and methods for inhibiting proliferation of vascular endothelial cells and tumor angiogenesis induced cell fusion. The invention further relates to compositions and methods preventing growth of, or promoting regression of, primary tumors and metastases; and for treating cancer, diabetic retinopathy, progressive macular degeneration or rheumatoid arthritis.
摘要翻译：本发明涉及包含血管生成抑制肽（例如内皮抑素肽（包括但不限于其片段和变体））的蛋白质，其表现出与白蛋白融合或缀合的抗逆转录病毒活性（包括但不限于片段或变体的白蛋白）。这些融合蛋白在本文中统称为“本发明的白蛋白融合蛋白”。这些融合蛋白在本文中统称为“本发明的白蛋白融合蛋白”。这些融合蛋白在溶液中表现出延长的保质期和/或延长或治疗活性。本发明包括治疗性白蛋白融合蛋白，组合物，药物组合物，制剂和试剂盒。本发明还包括编码本发明的白蛋白融合蛋白的核酸分子以及含有这些核酸的载体，用这些核酸和载体转化的宿主细胞，以及使用这些核酸制备本发明的白蛋白融合蛋白的方法，载体和/或宿主细胞。本发明还涉及抑制血管内皮细胞增殖和肿瘤血管生成诱导的细胞融合的组合物和方法。本发明还涉及预防原发性肿瘤和转移瘤的生长或促进消退的组合物和方法; 并用于治疗癌症，糖尿病性视网膜病变，进行性黄斑变性或类风湿性关节炎。

3. 发明申请

US20080274969A1 Albumin-Fused Kunitz Domain Peptides 审中-公开
标题翻译：白蛋白融合Kunitz结构域肽
公开(公告)号：US20080274969A1
公开(公告)日：2008-11-06
申请号：US12114477
申请日：2008-05-02
申请人： Hans-Peter Hauser , Thomas Weimer , Val Romberg , Scott M. Kee , Darrell Sleep , Robert Charles Ladner , Arthur C. Ley
发明人： Hans-Peter Hauser , Thomas Weimer , Val Romberg , Scott M. Kee , Darrell Sleep , Robert Charles Ladner , Arthur C. Ley
IPC分类号： A61K38/38 , C07K14/76 , C07H21/00 , C12N15/00 , C12N5/00 , C12P21/04
CPC分类号： C12N15/62 , C07K2319/31
摘要： The invention relates to proteins comprising serine protease inhibiting peptides, such as Kunitz domain peptides (including, but not limited to, fragments and variants thereof) fused to albumin, or fragments or variants thereof. These fusion proteins are herein collectively referred to as “albumin fusion proteins of the invention.” These fusion proteins exhibit extended shelf-life and/or extended or therapeutic activity in solution. The invention encompasses therapeutic albumin fusion proteins, compositions, pharmaceutical compositions, formulations and kits. The invention also encompasses nucleic acid molecules and vectors encoding the albumin fusion proteins of the invention, host cells transformed with these nucleic acids and vectors, and methods of making the albumin fusion proteins of the invention using these nucleic acids, vectors, and/or host cells. The invention also relates to compositions and methods for inhibiting neutrophil elastase, kallikrein, and plasmin. The invention further relates to compositions and methods for treating cystic fibrosis and cancer.
摘要翻译：本发明涉及包含丝氨酸蛋白酶抑制肽的蛋白质，例如与白蛋白或其片段或变体融合的Kunitz结构域肽（包括但不限于其片段和变体）。这些融合蛋白在本文中统称为“本发明的白蛋白融合蛋白”。这些融合蛋白在溶液中表现出延长的保质期和/或延长或治疗活性。本发明包括治疗性白蛋白融合蛋白，组合物，药物组合物，制剂和试剂盒。本发明还包括编码本发明的白蛋白融合蛋白，用这些核酸和载体转化的宿主细胞的核酸分子和载体，以及使用这些核酸，载体和/或宿主制备本发明的白蛋白融合蛋白的方法细胞。本发明还涉及抑制嗜中性粒细胞弹性蛋白酶，激肽释放酶和纤溶酶的组合物和方法。本发明还涉及治疗囊性纤维化和癌症的组合物和方法。

4. 发明授权

US07338770B2 Human procalcitonin and the preparation and use thereof 有权
标题翻译：人类降钙素原及其制备和应用
公开(公告)号：US07338770B2
公开(公告)日：2008-03-04
申请号：US11055622
申请日：2005-02-11
申请人： Harald Althaus , Hans-Peter Hauser
发明人： Harald Althaus , Hans-Peter Hauser
IPC分类号： G01N33/53 , G01N33/566 , C12N5/06 , C12N9/96 , A61K38/00
CPC分类号： C07K14/585 , A61K38/00 , C07K2319/00 , Y10S435/967
摘要： The invention relates to human procalcitonin and the preparation and use thereof. In particular, a process for preparing human procalcitonin is described wherein a gene coding for a polypeptide comprising the amino acid sequence of human procalcitonin is inserted into a vector; a host organism is transformed with this gene-containing vector; and the polypeptide expressed by the host organism is isolated. Furthermore the use of the polypeptides according to the invention, in particular as medicaments and diagnostic agents is described.
摘要翻译：本发明涉及人类降钙素原及其制备和应用。具体地，描述了一种制备人降钙素原的方法，其中将编码包含人降钙素原的氨基酸序列的多肽的基因插入载体中; 用含该基因的载体转化宿主生物; 并分离由宿主生物表达的多肽。此外，描述了根据本发明的多肽，特别是作为药物和诊断剂的用途。

5. 发明申请

US20070264627A1 Retrovirus from the HIV group and its use 审中-公开
标题翻译：来自HIV组的逆转录病毒及其用途
公开(公告)号：US20070264627A1
公开(公告)日：2007-11-15
申请号：US11634155
申请日：2006-12-06
申请人： Lutz Guertler , Josef Eberle , Albrecht Brunn , Stefan Knapp , Hans-Peter Hauser
发明人： Lutz Guertler , Josef Eberle , Albrecht Brunn , Stefan Knapp , Hans-Peter Hauser
IPC分类号： C12Q1/70 , C12N7/00
CPC分类号： G01N33/56988 , A61K39/00 , C07K14/005 , C12N2740/16021 , C12N2740/16022 , C12N2740/16122 , C12N2740/16222 , C12Q1/703
摘要： A novel immunodeficiency virus is disclosed which has the designation MVP-5180/91 and which has been deposited with the European Collection of Animal Cell Cultures (ECACC) under No. V 920 52 318. The characteristic antigens which can be obtained from it and which can be employed for detecting antibodies against retroviruses which are associated with immunodeficiency diseases are also disclosed, as are the DNA and amino acid sequences of the virus.
摘要翻译：公开了一种新型免疫缺陷病毒，其名称为MVP-5180/91，并且已经在欧洲动物细胞培养物收集库（ECACC）V 920 52 318下保藏。可从其中获得的特征性抗原，其中可以用于检测与免疫缺陷病相关的逆转录病毒的抗体，以及病毒的DNA和氨基酸序列也被公开。

6. 发明授权

US07135186B2 Varicella zoster virus (VZV) immunoreactive protein VP26 and its diagnostic use 失效
标题翻译：水痘带状疱疹病毒（VZV）免疫反应蛋白VP26及其诊断用途
公开(公告)号：US07135186B2
公开(公告)日：2006-11-14
申请号：US09874140
申请日：2001-06-06
申请人： Markus Eickmann , Dorothee Gicklhorn , Klaus Radsak , Hans-Peter Hauser , Bernhard Giesendorf
发明人： Markus Eickmann , Dorothee Gicklhorn , Klaus Radsak , Hans-Peter Hauser , Bernhard Giesendorf
IPC分类号： A61K39/245
CPC分类号： C07K14/005 , C12N2710/16722
摘要： Varicella zoster virus (VZV) inimunoreactive protein VP26 and its diagnostic use are described. The invention relates to immunoreactive peptides which are homologous with the region of amino acid positions 12 to 235 (SEQ ID NO: 7) of the varicella zoster virus protein VP26, to nucleic acids which encode these peptides and to the use of the peptides or nucleic acids for diagnosing an infection with varicella zoster virus.
摘要翻译：描述了水痘带状疱疹病毒（VZV）反义蛋白VP26及其诊断用途。本发明涉及与水痘带状疱疹病毒蛋白VP26的氨基酸位置12至235（SEQ ID NO：7）区域同源于与编码这些肽的核酸以及使用肽或核酸的免疫反应性肽用于诊断水痘带状疱疹病毒感染的酸。

7. 发明授权

US06905687B2 Human procalcitonin and the preparation and use thereof 有权
公开(公告)号：US06905687B2
公开(公告)日：2005-06-14
申请号：US10394058
申请日：2003-03-24
申请人： Harald Althaus , Hans-Peter Hauser
发明人： Harald Althaus , Hans-Peter Hauser
IPC分类号： C12N15/09 , A61K9/08 , A61K38/00 , A61K38/23 , A61K39/395 , A61K47/28 , A61K47/42 , A61P3/14 , A61P5/22 , A61P35/04 , C07J9/00 , C07K14/585 , C07K16/26 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/16 , C12P21/02 , C12P21/08 , C07K14/435 , G01N33/53
CPC分类号： C07K14/585 , A61K38/00 , C07K2319/00 , Y10S435/967
摘要： The invention relates to human procalcitonin and the preparation and use thereof. In particular, a process for preparing human procalcitonin is described wherein a gene coding for a polypeptide comprising the amino acid sequence of human procalcitonin is inserted into a vector; a host organism is transformed with this gene-containing vector; and the polypeptide expressed by the host organism is isolated. Furthermore the use of the polypeptides according to the invention, in particular as medicaments and diagnostic agents is described.

8. 发明申请

US20050053920A1 Retrovirus from the HIV group and its use 审中-公开
标题翻译：来自HIV组的逆转录病毒及其用途
公开(公告)号：US20050053920A1
公开(公告)日：2005-03-10
申请号：US10829442
申请日：2004-04-22
申请人： Lutz Guertler , Josef Eberle , Albrecht Brunn , Stefan Knapp , Hans-Peter Hauser
发明人： Lutz Guertler , Josef Eberle , Albrecht Brunn , Stefan Knapp , Hans-Peter Hauser
IPC分类号： A61K39/21 , A61K39/00 , A61P31/12 , A61P31/18 , C07K14/00 , C07K14/155 , C07K14/16 , C12N5/02 , C12N7/00 , C12N7/01 , C12N15/09 , C12N15/48 , C12P21/02 , C12Q1/68 , C12Q1/70 , G01N33/53 , G01N33/569 , G01N33/68
CPC分类号： G01N33/56988 , A61K39/00 , C07K14/005 , C12N2740/16021 , C12N2740/16022 , C12N2740/16122 , C12N2740/16222 , C12Q1/703
摘要： A novel immunodeficiency virus is disclosed which has the designation MVP-5180/91 and which has been deposited with the European Collection of Animal Cell Cultures (ECACC) under No. V 920 52 318. The characteristic antigens which can be obtained from it and which can be employed for detecting antibodies against retroviruses which are associated with immunodeficiency diseases are also disclosed, as are the DNA and amino acid sequences of the virus.
摘要翻译：公开了一种新型免疫缺陷病毒，其名称为MVP-5180/91，并且已经在欧洲动物细胞培养物收集库（ECACC）V 920 52 318下保藏。可从其中获得的特征性抗原，其中可以用于检测与免疫缺陷病相关的逆转录病毒的抗体，以及病毒的DNA和氨基酸序列也被公开。

9. 发明授权

US06566513B1 Lentivirus from the group of immunodeficiency viruses of drill monkeys (Mandrillus leucophaeus) and their use 失效
标题翻译：来自钻猴（Mandrillus leucophaeus）的免疫缺陷病毒组的慢病毒及其用途
公开(公告)号：US06566513B1
公开(公告)日：2003-05-20
申请号：US09625972
申请日：2000-07-26
申请人： Lutz Gerhard Guertler , Hans Peter Hauser , Yvette Beatrice Dongmo Deloko , Leopold Zekeng , Lazare Kaptue
发明人： Lutz Gerhard Guertler , Hans Peter Hauser , Yvette Beatrice Dongmo Deloko , Leopold Zekeng , Lazare Kaptue
IPC分类号： C07H2104
CPC分类号： C07K14/005 , C12N7/00 , C12N2740/15021 , C12N2740/15022 , Y10S530/826
摘要： The present invention relates to an immunodeficiency virus of drill monkeys, its RNA, the corresponding cDNA, proteins derived therefrom and fragments of the nucleic acids or proteins. The invention likewise relates to the diagnostic use of the nucleic acids and proteins mentioned and their fragments and to a diagnostic.
摘要翻译：本发明涉及钻猴的免疫缺陷病毒，其RNA，相应的cDNA，从其衍生的蛋白质和核酸或蛋白质的片段。本发明同样涉及所提及的核酸和蛋白质及其片段和诊断用途的诊断用途。

10. 发明授权

US06562946B2 Human procalcitonin and the preparation and use thereof 有权
公开(公告)号：US06562946B2
公开(公告)日：2003-05-13
申请号：US09742373
申请日：2000-12-22
申请人： Harald Althaus , Hans-Peter Hauser
发明人： Harald Althaus , Hans-Peter Hauser
IPC分类号： C07K14585
CPC分类号： C07K14/585 , A61K38/00 , C07K2319/00 , Y10S435/967
摘要： The invention relates to human procalcitonin and the preparation and use thereof. In particular, a process for preparing human procalcitonin is described wherein a gene coding for a polypeptide comprising the amino acid sequence of human procalcitonin is inserted into a vector; a host organism is transformed with this gene-containing vector; and the polypeptide expressed by the host organism is isolated. Furthermore the use of the polypeptides according to the invention, in particular as medicaments and diagnostic agents is described.

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