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1. 发明授权

US09999354B2 Biological tissue inspection method and system 有权
公开(公告)号：US09999354B2
公开(公告)日：2018-06-19
申请号：US13353797
申请日：2012-01-19
申请人： Guy Rousseau , Alain Blouin , Jean-Pierre Monchalin
发明人： Guy Rousseau , Alain Blouin , Jean-Pierre Monchalin
IPC分类号： A61B5/00 , G01N21/17 , G01N29/24
CPC分类号： A61B5/0093 , A61B5/0059 , A61B5/0095 , A61B5/0097 , G01N21/1702 , G01N21/171 , G01N29/2418 , G01N2291/02475
摘要： A method and system for inspecting biological tissue that has no applied coatings or treatments to improve reflectivity comprises an optical detection system with an exposed surface for inspection by an optical detection system; and a laser for exciting an ultrasonic wave within the tissue, which wave propagates within the tissue at least near the surface. The optical detection system includes: a laser to emit a pulsed detection laser beam onto the surface at a detection spot, the pulsed laser beam having a wavelength at which there is large scattering and little absorption by the tissue, and a pulse duration is chosen to correspond with ultrasonic propagation times associated with a range of depths of the scan, whereby the fluence of the detection laser is not applied unless ultrasonic information regarding a given depth is being obtained; and large étendue collection optics for collecting reflected and backscattered light from the detection spot; and a demodulator to extract information from the ultrasonic wave from the collected light.

2. 发明授权

US07094552B2 Diagnostic test kits 有权
公开(公告)号：US07094552B2
公开(公告)日：2006-08-22
申请号：US10272601
申请日：2002-10-16
申请人： Jean-Paul Thomasi , Michel Gersdorff , Guy Rousseau
发明人： Jean-Paul Thomasi , Michel Gersdorff , Guy Rousseau
IPC分类号： G01N33/53 , G01N33/559 , G01N33/564
CPC分类号： A61K38/1709 , A61K39/0008 , A61K2039/542 , A61K2039/6037 , G01N33/564 , G01N2800/14 , Y10S435/81
摘要： The invention provides a method for the treatment of prophylaxis of autoimmune inner ear disease, in particular, deafness caused by autoimmune inner ear disease, which comprises administering to a host in need thereof a vaccine comprising peripheral myelin protein zero. The invention further provides diagnostic methods and kits derived from the protein.

3. 发明申请

US20120200845A1 BIOLOGICAL TISSUE INSPECTION METHOD AND SYSTEM 有权
标题翻译：生物组织检查方法与系统
公开(公告)号：US20120200845A1
公开(公告)日：2012-08-09
申请号：US13353797
申请日：2012-01-19
申请人： Guy ROUSSEAU , Alain BLOUIN , Jean-Pierre MONCHALIN
发明人： Guy ROUSSEAU , Alain BLOUIN , Jean-Pierre MONCHALIN
IPC分类号： G01N21/55 , G01B9/02
CPC分类号： A61B5/0093 , A61B5/0059 , A61B5/0095 , A61B5/0097 , G01N21/1702 , G01N21/171 , G01N29/2418 , G01N2291/02475
摘要： A method and system for inspecting biological tissue that has no applied coatings or treatments to improve reflectivity comprises an optical detection system with an exposed surface for inspection by an optical detection system; and a laser for exciting an ultrasonic wave within the tissue, which wave propagates within the tissue at least near the surface. The optical detection system includes: a laser to emit a pulsed detection laser beam onto the surface at a detection spot, the pulsed laser beam having a wavelength at which there is large scattering and little absorption by the tissue, and a pulse duration is chosen to correspond with ultrasonic propagation times associated with a range of depths of the scan, whereby the fluence of the detection laser is not applied unless ultrasonic information regarding a given depth is being obtained; and large étendue collection optics for collecting reflected and backscattered light from the detection spot; and a demodulator to extract information from the ultrasonic wave from the collected light.
摘要翻译：用于检查没有施加涂层或处理以改善反射率的生物组织的方法和系统包括具有暴露表面的光学检测系统，用于由光学检测系统检查; 以及用于激发组织内的超声波的激光，该波在组织内至少在表面附近传播。光学检测系统包括：激光器，其在检测点处在表面上发射脉冲检测激光束，脉冲激光束具有散射大且组织吸收小的波长，脉冲持续时间选择为对应于与扫描深度范围相关联的超声传播时间，由此除非获得关于给定深度的超声信息，否则不应用检测激光的注量; 和用于收集来自检测点的反射和反向散射光的大型收集光学元件; 以及解调器，用于从收集的光提取来自超声波的信息。

4. 发明授权

US6120619A Passivation of stainless steels in organosulphonic acid medium 失效
标题翻译：在有机磺酸介质中钝化不锈钢
公开(公告)号：US6120619A
公开(公告)日：2000-09-19
申请号：US228953
申请日：1999-01-12
申请人： Jean Goudiakas , Guy Rousseau
发明人： Jean Goudiakas , Guy Rousseau
IPC分类号： C23F11/18 , C23F11/04 , C23C22/48
CPC分类号： C23F11/04
摘要： To avoid the corrosion of stainless steels in organosulphonic acid medium, at least one oxidizing agent selected from cerium(IV), iron(III), molybdenum(VI) or vanadium(V) oxides or salts, nitrites and persulphates, is added to the medium in an amount which is sufficient to place the spontaneous potential between the passivation and transpassivation potentials.
摘要翻译：为了避免不锈钢在有机磺酸介质中的腐蚀，将至少一种选自铈（IV），铁（III），钼（VI）或钒（V））氧化物或盐，亚硝酸盐和过硫酸盐的氧化剂加入到介质的量足以将自发电位置于钝化和钝化电位之间。

5. 发明授权

US07092414B2 Method for characterization of laser pulses using pulse quality factor 失效
标题翻译：使用脉冲质量因子表征激光脉冲的方法
公开(公告)号：US07092414B2
公开(公告)日：2006-08-15
申请号：US10429948
申请日：2003-05-06
申请人： Michel Piché , Guy Rousseau
发明人： Michel Piché , Guy Rousseau
IPC分类号： H01S3/10
CPC分类号： G01J11/00 , G01J1/42
摘要： There is described a method of characterizing a short laser pulse, the method comprising the steps of obtaining root-mean-square widths of the pulse through second order moments of the pulse; obtaining a spectral width of the pulse using the root-mean-square widths; obtaining a root-mean square temporal width of the pulse; and defining a Pulse Quality Factor proportional to a product of the spectral width and the temporal width. This approach does not require complete characterization of laser pulses and eliminates the need of any assumption to interpret autocorrelation traces. The method can be applied to pulses of arbitrary shape.
摘要翻译：描述了表征短激光脉冲的方法，该方法包括以下步骤：通过脉冲的二阶矩获得脉冲的均方根宽度; 使用均方根宽度获得脉冲的光谱宽度; 获得脉冲的均方根时间宽度; 并且定义与光谱宽度和时间宽度的乘积成比例的脉冲质量因子。这种方法不需要激光脉冲的完整表征，也不需要任何解释自相关曲线的假设。该方法可以应用于任意形状的脉冲。

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