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1. 发明申请

US20070255353A1 FAULT TOLERANT CO-AXIALLY WIRED SENSORS AND METHODS FOR IMPLEMENTING SAME IN AN IMPLANTABLE MEDICAL DEVICE 审中-公开
标题翻译：用于在可植入医疗装置中实施相同容许的同轴线性传感器和方法
公开(公告)号：US20070255353A1
公开(公告)日：2007-11-01
申请号：US11380548
申请日：2006-04-27
申请人： James Reinke , Jonathan Roberts , Glenn Roline , Barbara Schmid
发明人： James Reinke , Jonathan Roberts , Glenn Roline , Barbara Schmid
IPC分类号： A61N1/16
CPC分类号： A61N1/3706 , A61N1/3718 , A61N1/37288
摘要： According to the invention, a possible fault scenario involves an insulation breach of a medical lead which couples signals and/or electrical energy between a sensor and a circuit-bearing, active implantable medical device (AIMD). An initial response involves disconnecting the power source from the sensor with subsequent responses including selective reconnection of the power source. If the fault spontaneously resolves, then power to the sensor can be restored and physiologic signals transmitted to operative circuitry of the AIMD. In addition, however, an intermediate mode is enabled with the power source only coupled temporarily, for example, during intervals when stimulation and/or capture of excitable tissue (e.g., myocardial tissue) is not likely to occur due to any electrical shunt current(s). Thus, applying energy to a sensor(s) during the refractory period of a cardiac chamber eliminates undesired tissue activation. Moreover, sensed physiologic parameters can be collected without interrupting therapy delivery
摘要翻译：根据本发明，可能的故障情况涉及在传感器和带电路的有源可植入医疗装置（AIMD）之间耦合信号和/或电能的医疗引线的绝缘破裂。初始响应包括将电源与传感器断开连接，随后的响应包括电源的选择性重新连接。如果故障自发解决，则可以恢复传感器的电源，并将生理信号传输到AIMD的操作电路。然而，另外，中间模式仅能够暂时耦合电源，例如在由于任何分流电流而不可能发生兴奋性组织（例如，心肌组织）的刺激和/或捕获的间隔期间） s）。因此，在心室的不应期期间向传感器施加能量消除了不需要的组织活化。此外，可以收集感测的生理参数而不中断治疗递送

2. 发明申请

US20070265674A1 FAULT TOLERANT IMPLANTABLE SENSORS HAVING REDUNDANT ELECTRICAL GROUNDING CONNECTIONS 审中-公开
标题翻译：具有冗余电气接地连接的容错可移植传感器
公开(公告)号：US20070265674A1
公开(公告)日：2007-11-15
申请号：US11380562
申请日：2006-04-27
申请人： John Olson , Glenn Roline , Jonathan Roberts , Keith Ufford
发明人： John Olson , Glenn Roline , Jonathan Roberts , Keith Ufford
IPC分类号： A61N1/375 , A61N1/00
CPC分类号： A61N1/3706 , A61N1/372
摘要： Methods and apparatus according to the disclosure include without limitation the following. A method for providing fault tolerance to an active implantable medical device (AIMD) coupled via a medical electrical lead to an implantable physiologic sensor (IPS), including a conductive member or structure for imparting a biasing force to a proximal portion of the lead. The conductive member electrically couples to a source of reference electrical potential (i.e., electrical ground) and neither contacts nor conducts a source of power for the IPS. The conductive member can include threads and interlocking tool-receiving portions and can be shielded from contact with body fluid(s) by a seal-healing grommet or septum. Furthermore, a set screw can serve as the conductive member and the set screw can include an Allen wrench receptacle or a screwdriver receptacle or equivalent.
摘要翻译：根据本公开的方法和装置包括但不限于以下。一种用于向通过医疗电线耦合到可植入生理传感器（IPS）的有源可植入医疗装置（AIMD）提供容错的方法，该可植入生理传感器包括用于向铅的近端部分施加偏置力的导电构件或结构。导电构件电耦合到参考电位源（即，电接地），并且两者都不接触或传导IPS的电源。导电构件可以包括螺纹和互锁工具接收部分，并且可以通过密封愈合垫圈或隔膜来防止与体液的接触。此外，固定螺钉可以用作导电构件，并且固定螺钉可以包括内六角扳手插座或螺丝刀插座或等同物。

3. 发明申请

US20070265669A1 FAULT TOLERANT IMPLANTABLE PULSE GENERATORS AND IMPLANTABLE CARDIOVERTER-DEFIBRILLATORS INCORPORATING PHYSIOLOGIC SENSORS AND METHODS FOR IMPLEMENTING FAULT TOLERANCE IN SAME 有权
标题翻译：包含生理传感器的容错可移植脉冲发生器和可植入的减速器 - 除颤器以及在其中实施故障耐力的方法
公开(公告)号：US20070265669A1
公开(公告)日：2007-11-15
申请号：US11380567
申请日：2006-04-27
申请人： Glenn Roline , Michael Terry , Jonathan Roberts , James Reinke , Robert Corey
发明人： Glenn Roline , Michael Terry , Jonathan Roberts , James Reinke , Robert Corey
IPC分类号： A61N1/39
CPC分类号： A61N1/36564 , A61N1/3605 , A61N1/36514 , A61N1/36557 , A61N2001/083
摘要： This disclosure relates to fault tolerant instantiations of a cardiac therapy delivery device such as an implantable cardiac stimulator (e.g., an implantable pulse generator, IPG, and/or an implantable cardioverter-defibrillator, ICD) coupled to an implantable physiologic sensor (IPS). According to the disclosure delivery of cardiac pacing and/or cardioversion-defibrillator therapy delivery can cause errors in output signals from an IPS. Resolution of such errors involves selectively energizing (or disconnecting the output signal from) the IPS during pacing and/or defibrillation therapy delivery. Programmable signal “blanking” in lieu of or in addition to the foregoing also improves the integrity of the output signal (i.e., continuously energize the IPS and ignore parts of the output signal). An ICD having a transient weakness in an insulated conductor used for the IPS signal can likewise have the IPS de-energized and/or blank the IPS output signal during high voltage therapy delivery.
摘要翻译：本公开涉及心脏治疗递送装置的容错实例，例如可植入的心脏刺激器（例如，可植入脉冲发生器，IPG和/或植入式心律转复除颤器，ICD），其与可植入生理传感器（IPS）耦合。根据心脏起搏和/或心脏复律 - 除颤器治疗传递的披露递送可能导致来自IPS的输出信号的错误。这种错误的解决涉及在起搏和/或除颤治疗递送期间选择性地激励（或断开输出信号）IPS。代替或除了上述之外的可编程信号“消隐”也提高了输出信号的完整性（即，连续地激励IPS并忽略输出信号的部分）。在IPS信号中使用的绝缘导体具有瞬时弱点的ICD同样可以在高电压治疗传送期间使IPS不通电和/或空白IPS输出信号。

4. 发明授权

US4363325A Mode adaptive pacer 失效
标题翻译：模式自适应起搏器
公开(公告)号：US4363325A
公开(公告)日：1982-12-14
申请号：US226304
申请日：1981-01-19
申请人： Glenn Roline , Frank Walmsley
发明人： Glenn Roline , Frank Walmsley
IPC分类号： A61N1/362 , A61N1/36
CPC分类号： A61N1/3622
摘要： A multiple-mode pacer which automatically switches from an atrial synchronous mode to a ventricular inhibited mode when the intrinsic atrial rate drops below a preset hysteresis rate. This mode switching prevents atrial bradycardia from resulting in the delivery of closely spaced ventricular stimulating pulses.
摘要翻译：当固有心率下降到预设滞后速率以下时，多模式起搏器能够自动地从心房同步模式切换到心室抑制模式。该模式切换防止心房心动过缓导致紧密间隔的心室刺激脉冲的传递。

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