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1. 发明授权

US6090097A Aortic occluder with associated filter and methods of use during cardiac surgery 失效
公开(公告)号：US6090097A
公开(公告)日：2000-07-18
申请号：US8647
申请日：1998-01-16
申请人： Denise Barbut , Giovanni Pastrone , Tracy D. Maahs , Ross S. Tsugita
发明人： Denise Barbut , Giovanni Pastrone , Tracy D. Maahs , Ross S. Tsugita
IPC分类号： A61B17/00 , A61B17/12 , A61F2/01 , A61F2/02 , A61F2/958 , A61M31/00
CPC分类号： A61F2/013 , A61B17/12022 , A61B17/12109 , A61B17/12136 , A61B17/12172 , A61F2/01 , A61B2017/00243 , A61F2002/018 , A61F2230/0006 , A61F2230/0065 , A61F2230/0067 , A61F2250/0003 , A61M2025/0073 , A61M2025/1052 , A61M2210/127
摘要： A balloon arterial cannula and methods for filtering blood. The devices generally include a mesh for filtering blood flowing within a blood vessel, particularly within an artery such as the aorta, a structure adapted to open and close the mesh within the blood vessel, a means to actuate the structure, and a balloon occluder which typically includes a flexible material enclosing a chamber. The methods generally include the steps of introducing a mesh into a blood vessel to capture embolic material, adjusting the mesh, if necessary, during the course of filtration, inflating the balloon occluder to occlude the vessel upstream of the mesh, and thereafter deflating the balloon occluder and removing the mesh and the captured foreign matter from the blood vessel. Additionally, visualization techniques are used to ensure effective filtration.

2. 发明授权

US6060713A X-ray detector 有权
标题翻译： X射线探测器
公开(公告)号：US6060713A
公开(公告)日：2000-05-09
申请号：US152079
申请日：1998-09-11
申请人： Brian Skillicorn , Giovanni Pastrone
发明人： Brian Skillicorn , Giovanni Pastrone
IPC分类号： A61B6/03 , A61B6/06 , A61B6/12 , G01T1/20 , G01T1/202 , G01T1/29 , G21K1/02 , H01J35/14 , H05G1/10 , H05G1/64
CPC分类号： H05G1/64 , A61B6/06 , A61B6/12 , A61B6/4028 , G01T1/2018 , G01T1/202 , G01T1/2971 , G21K1/025 , H01J35/14 , H05G1/10 , A61B6/4488 , A61B6/487
摘要： A detector comprising a plurality of densely packed x-ray detectors arranged into an array. Each detector preferably comprises a scintillator element which is optically coupled to a photodetector element, preferably with a fiber optic link. Each photodetector element is preferably optically separate from adjacent photodetector elements. The detector array preferably includes integral alignment means to align the scintillator elements with the photodetector elements. The scintillator array elements are preferably formed from materials which possess a fast response and a minimum afterglow time.
摘要翻译：一种检测器，包括布置成阵列的多个密集堆积的x射线检测器。每个检测器优选地包括闪光体元件，该闪烁器元件光学耦合到光电检测器元件，优选地具有光纤链路。每个光检测器元件优选地与相邻光电检测器元件光学分离。检测器阵列优选地包括使闪烁体元件与光电检测器元件对准的整体对准装置。闪烁体阵列元件优选由具有快速响应和最小余辉时间的材料形成。

3. 发明授权

US4703775A Liquid flow regulator 失效
标题翻译：液体流量调节器
公开(公告)号：US4703775A
公开(公告)日：1987-11-03
申请号：US856723
申请日：1986-04-25
申请人： Giovanni Pastrone
发明人： Giovanni Pastrone
IPC分类号： F16K7/00 , A61M5/168 , F16K7/06 , F16K7/02 , F16K31/50
CPC分类号： F16K7/061 , A61M5/16877 , Y10T137/86734 , Y10T74/18584
摘要： A liquid flow regulator has a housing including an axial bore, an inlet, an outlet and a plurality of axial grooves opening endwise of the inlet and laterally of the housing into the bore. The grooves, which have different axial lengths, taper axially so that the cross-sectional area of each groove gradually decreases from the inlet to nothing at a point where the groove merges with the bore. An elastomeric stock fits within the bore. A plunger for expanding the sock radially outward into sealing engagement with the housing adjacent the bore is axially movable within the bore. Flow through the grooves and the bore is regulated by the axial position of the plunger and the minimum cross-sectional area of the tapered, axial grooves at the axial location where the sock seals the bore. Axial adjustment of the plunger sequentially opens and closes passage from the grooves through the bore to the bore outlet. The upper end of the plunger is provided with threads for engagement with internal threading in a passageway so that rotation of the plunger adjusts its axial position for control of the flow. The connection between the plunger and passageway threads is flexible so that the threads can be flexed out of engagement with each other when it is desired to axially and non-rotatively move the plunger to quickly place the regulator in a fully open or fully closed condition.
摘要翻译：液体流量调节器具有壳体，该壳体包括轴向孔，入口，出口和多个轴向槽，所述轴向槽沿着入口的端部开口并且将壳体的侧向开口到孔中。具有不同轴向长度的凹槽轴向渐缩，使得每个凹槽的横截面积在凹槽与孔合并的点处从入口逐渐减小到无。弹性体坯料配合在孔内。用于将袜子径向向外扩展以与邻近孔的壳体密封接合的柱塞可在孔内轴向移动。通过凹槽和孔的流动由柱塞的轴向位置和楔形密封孔的轴向位置处的锥形轴向凹槽的最小横截面面积来调节。柱塞的轴向调节顺序地打开和关闭从槽穿过孔到孔出口的通道。柱塞的上端设置有用于与通道中的内螺纹接合的螺纹，使得柱塞的旋转调节其轴向位置以控制流动。柱塞和通道螺纹之间的连接是柔性的，使得当期望轴向和非旋转地移动柱塞以将调节器快速放置在完全打开或完全关闭状态时，螺纹可以彼此偏离接合。

4. 发明授权

US07306575B2 Aortic occluder with associated filter and methods of use during cardiac surgery 有权
标题翻译：主动脉夹闭器与相关过滤器和心脏手术中使用的方法
公开(公告)号：US07306575B2
公开(公告)日：2007-12-11
申请号：US10619760
申请日：2003-07-14
申请人： Denise Barbut , Jonathan D. Root , Giovanni Pastrone , Tracy D. Maahs , Ross S. Tsugita
发明人： Denise Barbut , Jonathan D. Root , Giovanni Pastrone , Tracy D. Maahs , Ross S. Tsugita
IPC分类号： A61M29/00
CPC分类号： A61F2/013 , A61B17/12022 , A61B17/12109 , A61B17/12136 , A61B17/12172 , A61B2017/00243 , A61F2/01 , A61F2002/018 , A61F2230/0006 , A61F2230/0065 , A61F2230/0067 , A61F2250/0003 , A61M2025/0073 , A61M2025/1052 , A61M2210/127
摘要： A balloon arterial cannula and methods for filtering blood. The devices generally include a mesh for filtering blood flowing within a blood vessel, particularly within an artery such as the aorta, a structure adapted to open and close the mesh within the blood vessel, a means to actuate the structure, and a balloon occluder which typically includes a flexible material enclosing a chamber. The methods generally include the steps of introducing a mesh into a blood vessel to capture embolic material, adjusting the mesh, if necessary, during the course of filtration, inflating the balloon occluder to occlude the vessel upstream of the mesh, and thereafter deflating the balloon occluder and removing the mesh and the captured foreign matter from the blood vessel. Additionally, visualization techniques are used to ensure effective filtration.
摘要翻译：气囊动脉插管和血液过滤方法。这些装置通常包括用于过滤血管内的血液的网格，特别是在诸如主动脉的动脉内，适于打开和关闭血管内的网状物的结构，致动结构的装置和气囊封堵器通常包括围绕室的柔性材料。所述方法通常包括以下步骤：将网状物引入血管以捕获栓塞材料，如果需要，在过滤过程中调整网孔，使球囊封堵器膨胀以封闭网孔上游的容器，然后使气囊放气闭塞器并从血管中除去网状物和捕获的异物。此外，可视化技术用于确保有效的过滤。

5. 发明授权

US06309399B1 Atherectomy device having trapping and excising means for removal of plaque from the aorta and other arteries 有权
标题翻译：动脉粥样硬化切除装置具有用于从主动脉和其他动脉移除斑块的捕获和切除装置
公开(公告)号：US06309399B1
公开(公告)日：2001-10-30
申请号：US09656775
申请日：2000-09-07
申请人： Denise R. Barbut , Jonathan D. Root , Giovanni Pastrone
发明人： Denise R. Barbut , Jonathan D. Root , Giovanni Pastrone
IPC分类号： A61M2900
CPC分类号： A61B17/320783 , A61B8/0808 , A61B10/06 , A61B17/22031 , A61B17/221 , A61B17/32056 , A61B17/3207 , A61B17/32075 , A61B2010/0225 , A61B2017/00287 , A61B2017/22068 , A61B2017/22069 , A61B2017/2215 , A61B2017/306 , A61B2017/32004 , A61B2017/320064 , A61F2/01 , A61F2/013 , A61F2002/018 , A61F2230/0006 , A61F2230/0067 , A61F2230/0071 , A61F2230/008 , A61M25/00 , A61M2210/127
摘要： An arterial catheter system for removing plaque from the aorta and other arteries is disclosed. The system typically includes an elongate catheter member, a filtration apparatus disposed within the distal region, and an atherectomy assembly which includes a mechanism for trapping and holding mobile or fixed plaque and an excising mechanism for removing the plaque. In use, the catheter is positioned so that the atherectomy assembly lies within a region of interest, the filtration apparatus is deployed downstream of the region of interest, the plaque is trapped and held by a snare, vacuum, or other trapping means, and then the excising mechanism is activated to remove the plaque. Methods are also disclosed for removing plaque from the aorta and other arteries.
摘要翻译：公开了用于从主动脉和其它动脉移除斑块的动脉导管系统。该系统通常包括细长导管构件，设置在远侧区域内的过滤装置，以及动脉粥样组织切除组件，其包括用于捕获和保持移动或固定噬菌斑的机构和用于去除斑块的切除机构。在使用中，定位导管，使得动脉切除术组件位于感兴趣的区域内，过滤装置部署在感兴趣区域的下游，斑块被圈套，真空或其它捕获装置捕获并保持，然后激活切除机制以去除斑块。还公开了从主动脉和其他动脉中除去斑块的方法。

6. 发明授权

US06179851B2 Guiding catheter for positioning a medical device within an artery 有权
标题翻译：导管，用于将医疗装置定位在动脉内
公开(公告)号：US06179851B2
公开(公告)日：2001-01-30
申请号：US09335849
申请日：1999-06-15
申请人： Denise R. Barbut , Jonathan D. Root , Giovanni Pastrone
发明人： Denise R. Barbut , Jonathan D. Root , Giovanni Pastrone
IPC分类号： A61B1722
CPC分类号： A61B17/320783 , A61B8/0808 , A61B10/06 , A61B17/22031 , A61B17/221 , A61B17/32056 , A61B17/3207 , A61B17/32075 , A61B2010/0225 , A61B2017/00287 , A61B2017/22068 , A61B2017/22069 , A61B2017/2215 , A61B2017/306 , A61B2017/32004 , A61B2017/320064 , A61F2/01 , A61F2/013 , A61F2002/018 , A61F2230/0006 , A61F2230/0067 , A61F2230/0071 , A61F2230/008 , A61M25/00 , A61M2210/127
摘要： An arterial catheter system for removing plaque from the aorta and other arteries is disclosed. The system typically includes an elongate catheter member, a filtration apparatus disposed within the distal region, and an atherectomy assembly which includes a mechanism for trapping and holding mobile or fixed plaque and an excising mechanism for removing the plaque. In use, the catheter is positioned so that the atherectomy assembly lies within a region of interest, the filtration apparatus is deployed downstream of the region of interest, the plaque is trapped and held by a snare, vacuum, or other trapping device, and then the excising mechanism is activated to remove the plaque. Methods are also disclosed for removing plaque from the aorta and other arteries.
摘要翻译：公开了用于从主动脉和其它动脉移除斑块的动脉导管系统。该系统通常包括细长导管构件，设置在远侧区域内的过滤装置，以及动脉粥样组织切除组件，其包括用于捕获和保持移动或固定噬菌斑的机构和用于去除斑块的切除机构。在使用中，导管被定位成使得动脉切除术组件位于感兴趣的区域内，过滤装置部署在感兴趣区域的下游，斑块被圈套，真空或其它捕获装置捕获并保持，然后激活切除机制以去除斑块。还公开了从主动脉和其他动脉中除去斑块的方法。

7. 发明授权

US5769816A Cannula with associated filter 失效
标题翻译：插管与相关过滤器
公开(公告)号：US5769816A
公开(公告)日：1998-06-23
申请号：US640015
申请日：1996-04-30
申请人： Denise Barbut , Jonathan D. Root , Giovanni Pastrone , James M. Sellers , Robert Rizzari
发明人： Denise Barbut , Jonathan D. Root , Giovanni Pastrone , James M. Sellers , Robert Rizzari
IPC分类号： A61F2/01 , A61F2/02 , A61M29/00
CPC分类号： A61F2/013 , A61F2002/011 , A61F2002/018 , A61F2230/0006 , A61F2230/0067 , A61F2250/0003 , A61M2210/127
摘要： Devices and methods for filtering blood. The devices generally comprise: a mesh for filtering blood flowing within a blood vessel, particularly within an artery such as the aorta; a structure adapted to open and close the mesh within the blood vessel; and a means to actuate the structure. The methods generally include the following steps: introducing a mesh into a blood vessel to entrap embolic material; adjusting the mesh, if necessary, during the course of filtration; and removing the mesh and the entrapped foreign matter from the blood vessel. Additionally, visualization techniques are used to ensure effective filtration.
摘要翻译：用于过滤血液的装置和方法装置通常包括：用于过滤血管内血液流动的网格，特别是在诸如主动脉的动脉内的网; 适于打开和关闭血管内的网的结构; 以及启动结构的手段。所述方法通常包括以下步骤：将网状物引入血管以捕获栓塞物质; 如果需要，在过滤过程中调整网孔; 并从血管中除去网状物和夹带的异物。此外，可视化技术用于确保有效的过滤。

8. 发明授权

US5431627A Cassette identification system for use with a multi-program drug infusion pump 失效
标题翻译：用于多节目药物输液泵的盒式识别系统
公开(公告)号：US5431627A
公开(公告)日：1995-07-11
申请号：US151096
申请日：1993-11-12
申请人： Giovanni Pastrone , Robert G. Poli , Anthony C. Yung , Peter A. Holst
发明人： Giovanni Pastrone , Robert G. Poli , Anthony C. Yung , Peter A. Holst
IPC分类号： A61M5/168 , A61M5/172 , A61M1/00
CPC分类号： A61M5/172 , A61M2202/0482 , A61M2205/12 , A61M2205/6018 , A61M2205/6036 , A61M5/16827 , Y10S128/12
摘要： A identification system for a cassette pump wherein a plurality of different types of cassettes administer different types of drugs, and each type of cassette is characterized by a different type determinative indicia carried by the cassette, and the cassette pump includes a prime mover for actuating the plurality of different types of cassettes corresponding number of different operating modes, each operating mode being used with a corresponding different type of cassette, wherein the pump-cassette interface for receiving and actuating each of the different types of cassettes includes a sensor disposed at the pump-cassette interface, and when the sensor is engaged by the type determinative indicia of a cassette, the pump is able to identify the particular type cassette inserted into the pump, and initiate the operating mode of the pump associated with the specific type of cassette positioned at the pump-cassette interface.
摘要翻译：一种用于盒式泵的识别系统，其中多个不同类型的盒管理不同类型的药物，并且每种类型的盒的特征在于由盒携带的不同类型的确定性标记，并且盒式泵包括用于致动多个不同类型的盒具有相应数量的不同操作模式，每个操作模式与相应的不同类型的盒子一起使用，其中用于接收和致动每个不同类型的盒的泵盒接口包括设置在泵 - 盒式接口，并且当传感器通过盒的类型确定标记接合时，泵能够识别插入到泵中的特定类型的盒，并启动与定位的特定类型的盒相关联的泵的操作模式在泵盒接口处。

9. 外观设计

USD342312S Pump cassette 失效
公开(公告)号：USD342312S
公开(公告)日：1993-12-14
申请号：US817254
申请日：1992-01-06
申请人： Giovanni Pastrone , Peter A. Holst
设计人： Giovanni Pastrone , Peter A. Holst

10. 发明授权

US4639245A Fluid infusion pump driver 失效
标题翻译：液体输液泵驱动
公开(公告)号：US4639245A
公开(公告)日：1987-01-27
申请号：US811262
申请日：1985-12-20
申请人： Giovanni Pastrone , Leland D. Chamness
发明人： Giovanni Pastrone , Leland D. Chamness
IPC分类号： F04B43/02 , A61M1/00 , A61M5/142 , A61M5/20
CPC分类号： A61M5/14224 , Y10S128/01 , Y10T74/18576
摘要： A fluid infusion pump driver device for pumping fluid from the chamber of a disposable cassette. The pump driver includes a reciprocatable plunger which is driven by a stepping motor. The motor and plunger are coupled through a universal joint which provides a threaded connection translating the incremental angular movements of the motor into incremental linear movements of the plunger, and the plunger is coupled directly to the frame through a flexible leaf spring to prevent wear in the threaded connection from generating undue noise or creating accuracy problems.
摘要翻译：用于从一次性盒的腔室泵送流体的流体输液泵驱动装置。泵驱动器包括由步进电机驱动的可往复运动的活塞。马达和柱塞通过万向接头联接，该万向接头提供螺纹连接，将电动机的增量角运动转换成柱塞的增量线性运动，并且柱塞通过柔性板簧直接连接到框架，以防止在螺纹连接产生不适当的噪音或产生精度问题。

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