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1. 发明公开

US20230417637A1 UV COATINGS AND DYES FOR LASER CAPTURE MICRODISSECTION 审中-公开
公开(公告)号：US20230417637A1
公开(公告)日：2023-12-28
申请号：US18036137
申请日：2021-11-09
申请人： George Mason Research Foundation, Inc.
发明人： Lance A. LIOTTA , Alessandra Luchini KUNKEL , Marissa Ashton HOWARD , Amanda Haymond STILL , Harini SOMANCHI , Philip Andrew PAPPALARDO
IPC分类号： G01N1/28
CPC分类号： G01N1/2813 , G01N2001/284
摘要： Laser Capture Microdissection devices and methods are provided. A Laser Capture Microdissection device contains a transmissive film and a transfer film. The transmissive film includes a first material configured to transmit laser energy. The transfer film includes a second material configured to absorb UV-laser energy. The transfer film contains an absorptive substance to absorb UV-laser energy and convert it into heat.

2. 发明授权

US11747242B2 Compositions and methods for laser capture microdissection 有权
公开(公告)号：US11747242B2
公开(公告)日：2023-09-05
申请号：US16878926
申请日：2020-05-20
申请人： GEORGE MASON RESEARCH FOUNDATION, INC.
发明人： Lance Liotta , Virginia Espina , Nitin Agrawal , Alessandra Luchini Kunkel
IPC分类号： G01N1/00 , G01N1/28
CPC分类号： G01N1/2813 , G01N2001/284
摘要： Compositions and methods for the simultaneous capture and release using micropattern surfaces for tissue and cell microdissection. In one example, a patterned thermoplastic film has a first surface and a plurality of projections attached to and extending outwardly from the first surface. The projections form a pattern on the thermoplastic film.

3. 发明申请

US20230052825A1 ANTIMICROBIAL AND ANTICANCER PEPTIDES & CONJUGATES AND COMPOSITIONS, METHODS, ARTICLES & KITS RELATING THERETO 有权
公开(公告)号：US20230052825A1
公开(公告)日：2023-02-16
申请号：US17820013
申请日：2022-08-16
申请人： George Mason Research Foundation, Inc.
发明人： Barney Bishop , Saswata K. Sahoo , Justin Davis
IPC分类号： C07K14/47 , C07K14/00 , A61K47/65 , C12Q1/04
摘要： Peptides and conjugates are described herein, including peptides having antimicrobial and/or anticancer properties, as are compositions, articles, and kits comprising such peptides and conjugates, and methods for using the peptides and conjugates.

4. 发明授权

US11473064B2 Hybrid alphavirus-SARS-CoV-2 particle and methodology of making and using same 有权
公开(公告)号：US11473064B2
公开(公告)日：2022-10-18
申请号：US17505496
申请日：2021-10-19
申请人： GEORGE MASON RESEARCH FOUNDATION, INC.
发明人： Brian Hetrick , Yuntao Wu
IPC分类号： A61K39/00 , C12N15/86 , C12N7/00 , A01N63/00 , A61K39/12 , C12N9/02 , A61K39/215 , C12Q1/6897
摘要： Timely development of vaccines and antiviral drugs is critical to control the COVID-19 pandemic. Current methods for quantifying vaccine-induced neutralizing antibodies involve the use of pseudoviruses, such as the SARS-CoV-2 spike protein (S) pseudotyped lentivirus. However, these pseudoviruses contain structural proteins foreign to SARS-CoV-2, and require days to infect and express reporter genes. Here, the present application discloses composition and methodology for making and using a new hybrid alphavirus-SARS-CoV-2 (Ha-CoV-2) particle for rapid and accurate quantification of neutralization antibodies and viral variants.

5. 发明授权

US11447533B2 Antimicrobial and anticancer peptides and conjugates and compositions, methods, articles and kits relating thereto 有权
公开(公告)号：US11447533B2
公开(公告)日：2022-09-20
申请号：US16710921
申请日：2019-12-11
申请人： George Mason Research Foundation, Inc.
发明人： Barney Bishop , Saswata K. Sahoo , Justin Davis
IPC分类号： C07K14/01 , C07K14/47 , C07K14/00 , A61K47/65 , C12Q1/04 , A61K38/00
摘要： Peptides and conjugates are described herein, including peptides having antimicrobial and/or anticancer properties, as are compositions, articles, and kits comprising such peptides and conjugates, and methods for using the peptides and conjugates.

6. 发明申请

US20210334921A1 Career Accelerator Toolkit 有权
公开(公告)号：US20210334921A1
公开(公告)日：2021-10-28
申请号：US17237427
申请日：2021-04-22
申请人： George Mason Research Foundation, Inc.
发明人： Marc T. Austin , Eric Lawrence Woodall , Audra Meckstroth , David Anthony Lewis , Peter Rea
IPC分类号： G06Q50/20 , G06Q30/02 , G06Q10/10 , G06Q10/06 , G06N20/00 , G06F40/40
摘要： Software tools serve universities and their prospective and enrolled students in the development of clearly understood career pathways, attainment of skills, and transition to employment. Exemplary embodiments are designed to better reveal the connections between chosen majors, required coursework, developed skills, future employment, and regional labor markets, while also providing data to better understand a student's process of making educational and career choices when exposed to this data. An overall goal of the product is to affect increased enrollment and successful outcomes of underserved and non-traditional students through exposure to guaranteed transfer pathways, cost savings, timely matriculation, higher retention, and increased post-graduation job opportunities focused on regional job markets.

7. 发明申请

US20190158523A1 METHODS AND APPARATUS FOR APPLICATION ISOLATION 审中-公开
公开(公告)号：US20190158523A1
公开(公告)日：2019-05-23
申请号：US16250006
申请日：2019-01-17
申请人： George Mason Research Foundation, Inc.
发明人： Anup GHOSH , Yih HUANG , Jiang WANG , Angelos STAVROU
IPC分类号： H04L29/06 , G06F9/455 , G06F21/53 , G06F21/55
CPC分类号： H04L63/1425 , G06F9/45545 , G06F21/53 , G06F21/55 , G06F21/554 , G06F2009/45591 , G06F2221/034 , G06F2221/2149 , H04L63/1416
摘要： Processor(s) for detecting malicious software. A hardware virtual machine monitor (HVMM) operates under a host OS. Container(s) initialized with network application template(s) operate under a guest OS VM. A detection module operates under the guest OS VM includes a trigger detection module, a logging module and a container command module. The trigger detection module monitors activity on container(s) for a trigger event. The logging module writes activity report(s) in response to trigger event(s). The container command module issues command(s) in response to trigger event(s). The command(s) include a container start, stop and revert commands. A virtual machine control console operates under the host OS and starts/stops the HVMM. A container control module operates under the guest OSVM and controls container(s) in response to the command(s). The server communication module sends activity report(s) to a central collection network appliance that maintains a repository of activities for infected devices.

8. 发明申请

US20180046479A1 ON-DEMAND DISPOSABLE VIRTUAL WORK SYSTEM 审中-公开
公开(公告)号：US20180046479A1
公开(公告)日：2018-02-15
申请号：US15795977
申请日：2017-10-27
申请人： George Mason Research Foundation, Inc.
发明人： Anup K. GHOSH , Sushil JAJODIA , Yih HUANG , Jiang WANG
IPC分类号： G06F9/455 , G06F21/53
CPC分类号： G06F9/45533 , G06F9/45558 , G06F21/53 , G06F2009/45562 , G06F2009/45575
摘要： An on-demand disposable virtual work system that includes: a virtual machine monitor to host virtual machines, a virtual machine pool manager, a host operating system, a host program permissions list, and a request handler module. The virtual machine pool manager manages virtual machine resources. The host operating system interfaces with a user and virtual machines created with an image of a reference operating system. The host program permissions list may be a black list and/or a white list used to indicate allowable programs. The request handler module allows execution of the program if the program is allowable. If the program is not allowable, the host request handler module: denies program execution and urges a virtual machine specified by the virtual machine pool manager to execute the program. The virtual machine is terminated when the program closes.

9. 发明申请

US20150264059A1 MALWARE DETECTOR 有权
标题翻译：恶意软件检测器
公开(公告)号：US20150264059A1
公开(公告)日：2015-09-17
申请号：US14482793
申请日：2014-09-10
申请人： George Mason Research Foundation, Inc.
发明人： Angelos STAVROU , Sushil JAJODIA , Anup K. GHOSH , Rhandi MARTIN , Charalampos Andrianakis
IPC分类号： H04L29/06
CPC分类号： H04L63/1416 , G06F21/566 , G06F2221/2103 , G06F2221/2119 , H04L63/08 , H04L63/0884 , H04L63/145 , H04L67/02
摘要： A transparent proxy for malware detection includes a monitor module, a protocol determination module, a challenge generation module, a response determination module, and a data control module. The monitor module examines data originating from an application towards a remote server. The protocol determination module identifies the protocol type used for the data. The challenge generation module produces a challenge for the application based upon the protocol type, sends the challenge to the application, and maintains a state related to the data and the challenge. The response determination module makes a determination if an automatic non-interactive application response is received in response to the challenge from the application. The data control module allows the first data to continue to the remote server when the determination is valid. The data control module reports malware detection and blocks the data to continue to the remote server when the determination is invalid.
摘要翻译：用于恶意软件检测的透明代理包括监视器模块，协议确定模块，质询生成模块，响应确定模块和数据控制模块。监视器模块将从应用程序发送到远程服务器的数据进行检查。协议确定模块识别用于数据的协议类型。挑战生成模块基于协议类型为应用程序产生挑战，向应用程序发送挑战，并维护与数据和挑战相关的状态。响应确定模块确定响应于来自应用的挑战是否接收到自动非交互式应用响应。当确定有效时，数据控制模块允许第一数据继续到远程服务器。当确定无效时，数据控制模块报告恶意软件检测并阻止数据继续到远程服务器。

10. 发明申请

US20220167918A1 NON-INVASIVE WEARABLE BIOMECHANICAL AND PHYSIOLOGY MONITOR FOR INJURY PREVENTION AND REHABILITATION 有权
公开(公告)号：US20220167918A1
公开(公告)日：2022-06-02
申请号：US17651661
申请日：2022-02-18
申请人： GEORGE MASON RESEARCH FOUNDATION, INC.
发明人： Marissa A. Howard , Lance A. Liotta , Rachel Naidich , Matthew Luu Trang , Ish Sethi , Rebecca Woodhouse , Kshamata Neupane
IPC分类号： A61B5/00 , A61B5/11 , A61B5/01
摘要： A wearable device measures, tracks, and monitors a wearer's physical physiological conditions during a rehabilitation period. Metrics such as temperature, patellar shifting, limb circumference, and acceleration may be collected. Changes in monitored conditions may be assessed for detecting medical abnormalities which require specialized attention, including for example embolisms or infections. A networked communication system and various user interfaces may be used for medical support personnel and patients alike to stay updated with the patient's rehabilitation progress and to make adjustments in a patient's individual rehabilitation program.

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