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1. 发明授权

US5614178A Compositions for topical delivery of drugs comprising a mixture of high and low HLB surfactants and alkoxylated ether 失效
标题翻译：用于局部递送药物的组合物，其包含高HLB表面活性剂和低级HLB表面活性剂和烷氧基化醚的混合物
公开(公告)号：US5614178A
公开(公告)日：1997-03-25
申请号：US265975
申请日：1994-06-27
申请人： Roberta C. Bloom , George E. Deckner
发明人： Roberta C. Bloom , George E. Deckner
IPC分类号： A61K9/06 , A61K8/35 , A61K8/36 , A61K8/368 , A61K8/39 , A61K8/42 , A61K8/73 , A61K8/81 , A61K8/86 , A61K8/891 , A61K8/892 , A61K8/896 , A61K47/00 , A61K47/32 , A61K47/34 , A61Q19/00 , A61Q19/04 , A61Q19/08 , A61Q19/10 , A61K7/42 , A61K7/06 , A61K31/785
CPC分类号： A61K8/891 , A61K47/32 , A61K8/35 , A61K8/36 , A61K8/368 , A61K8/39 , A61K8/42 , A61K8/732 , A61K8/8152 , A61K8/8158 , A61K8/86 , A61K8/892 , A61K9/0014 , A61Q19/00 , A61Q19/04 , A61Q19/08 , A61Q19/10 , A61K2800/5426
摘要： The present invention relates to pharmaceutical compositions for topical application comprising a safe and effective amount of a pharmaceutical active, from about 0.1% to about 10.0% of a high molecular weight cationic polymer, from about 0.05% to about 5% of a high HLB non-ionic surfactant, and from about 0.1% to about 25% of an alkoxylated ether. In further embodiments, these compositions also comprise from about 0.01% to about 5% of a low HLB non-ionic surfactant.
摘要翻译：本发明涉及用于局部应用的药物组合物，其包含安全有效量的药物活性物质，约0.1％至约10.0％的高分子量阳离子聚合物，约0.05％至约5％的高HLB非阳离子聚合物，离子表面活性剂和约0.1％至约25％的烷氧基化醚。在另外的实施方案中，这些组合物还包含约0.01％至约5％的低HLB非离子表面活性剂。

2. 发明授权

US5573754A Photoprotective compositions 失效
标题翻译：光保护组合物
公开(公告)号：US5573754A
公开(公告)日：1996-11-12
申请号：US174590
申请日：1993-12-28
申请人： Rupali A. Kulkarni , George E. Deckner
发明人： Rupali A. Kulkarni , George E. Deckner
IPC分类号： A61K8/42 , A61K8/49 , A61K8/67 , A61Q17/04 , A61K7/42 , A61K7/40
CPC分类号： A61K8/678 , A61K8/42 , A61K8/4946 , A61Q17/04
摘要： High SPF value (about 8 or greater) sunscreen compositions having improved photoprotective properties by non-sunscreen mechanism. These compositions comprise allantoin; pantothenol; Vitamin E, its pharmaceutically-acceptable esters, or mixtures thereof; one or more sunscreen agents; and carrier material.
摘要翻译：具有通过非防晒机制改善的光保护性能的高SPF值（约8或更大）防晒组合物。这些组合物包含尿囊素; 泛酸维生素E，其药学上可接受的酯或其混合物; 一种或多种防晒剂; 和载体材料。

3. 发明授权

US5516508A Photoprotection compositions having improved efficiency 失效
标题翻译：具有提高效率的光保护组合物
公开(公告)号：US5516508A
公开(公告)日：1996-05-14
申请号：US329045
申请日：1994-10-25
申请人： Lauren A. Thaman , George E. Deckner , John P. Sottery
发明人： Lauren A. Thaman , George E. Deckner , John P. Sottery
IPC分类号： A61K8/37 , A61K8/81 , A61Q17/04 , A61K7/42
CPC分类号： A61K8/8147 , A61K8/37 , A61Q17/04 , Y10S514/938
摘要： Disclosed are improved topical compositions having improved efficiency such as improved sunscreen effectiveness for protecting the skin from the harmful effects of ultraviolet irradiation, such as sunburn and sun-induced premature aging of the skin.
摘要翻译：公开了改进的局部组合物，其具有改进的效率，例如改善的防晒效果，用于保护皮肤免受紫外线照射的有害影响，例如晒伤和太阳引起的皮肤过早老化。

4. 发明授权

US5439682A Combined personal cleansing and moisturizing compositions 失效
标题翻译：组合个人清洁和保湿组合物
公开(公告)号：US5439682A
公开(公告)日：1995-08-08
申请号：US35517
申请日：1993-03-22
申请人： Susan C. Wivell , George E. Deckner
发明人： Susan C. Wivell , George E. Deckner
IPC分类号： A61K8/00 , A61K8/04 , A61K8/31 , A61K8/36 , A61K8/37 , A61K8/39 , A61K8/40 , A61K8/42 , A61K8/44 , A61K8/46 , A61K8/86 , A61K8/89 , A61K8/891 , A61K8/92 , A61K8/97 , A61Q1/02 , A61Q1/14 , A61Q19/00 , A61Q19/10 , C08L83/04 , C11D1/02 , C11D3/16 , A61K6/00
CPC分类号： A61K8/39 , A61K8/046 , A61K8/442 , A61K8/86 , A61Q19/00 , A61Q19/10 , A61K2800/596 , Y10S514/846 , Y10S514/847
摘要： The present invention relates to compositions which provide both a skin cleansing and skin moisturizing benefit from the same product. These compositions provide improved lathering and cleansing characteristics, are extremely mild to the skin, and deliver a moisturizing agent to the skin. These compositions comprise at least one anionic surfactant, a dispersed, insoluble oil phase, at least one additional surfactant, an optional suspending agent, and water. This invention also relates to methods for providing combined cleansing and moisturization, and to methods for delivering these compositions as a foam.
摘要翻译：本发明涉及提供来自相同产品的皮肤清洁和皮肤保湿益处的组合物。这些组合物提供改善的起泡和清洁特性，对皮肤非常温和，并向皮肤递送保湿剂。这些组合物包含至少一种阴离子表面活性剂，分散的不溶性油相，至少一种另外的表面活性剂，任选的悬浮剂和水。本发明还涉及提供组合清洁和保湿的方法，以及将这些组合物作为泡沫输送的方法。

5. 发明授权

US5420118A Gel type cosmetic compositions 失效
标题翻译：凝胶型化妆品组合物
公开(公告)号：US5420118A
公开(公告)日：1995-05-30
申请号：US068564
申请日：1993-05-27
申请人： Noelle C. Alban , George E. Deckner
发明人： Noelle C. Alban , George E. Deckner
IPC分类号： A61K8/81 , A61K8/891 , A61K8/892 , A61K31/695 , A61Q19/00
CPC分类号： A61K8/892 , A61K8/042 , A61K8/8152 , A61K8/891 , A61Q19/00 , Y10S514/847
摘要： A skin care composition in the form of a substantially oil-free aqueous gel comprising a water-soluble humectant, a hydrophilic gelling agent and a specific silicone component. The compositions provide improved skin feel and residue characteristics together with excellent moisturizing, emolliency, rub-in and absorption characteristics.
摘要翻译：形式为基本上无油的水凝胶形式的护肤组合物，其包含水溶性湿润剂，亲水性胶凝剂和特定硅氧烷组分。该组合物提供改善的皮肤感觉和残留特征以及优异的保湿，润肤，擦洗和吸收特性。

6. 发明授权

US5380528A Silicone containing skin care compositions having improved oil control 失效
标题翻译：具有改进的油控制的含硅氧烷的护肤组合物
公开(公告)号：US5380528A
公开(公告)日：1995-01-10
申请号：US121672
申请日：1993-09-15
申请人： Noelle C. Alban , George E. Deckner
发明人： Noelle C. Alban , George E. Deckner
IPC分类号： A61K8/81 , A61K8/891 , A61K8/892 , A61K9/10 , A61Q19/00 , A61K7/48
CPC分类号： A61K8/416 , A61K8/8152 , A61K8/891 , A61K8/892 , A61Q19/00 , A61Q19/008 , Y10S514/859 , Y10S514/863 , Y10S514/864 , Y10S514/873 , Y10S514/944
摘要： A skin care composition in the form of a substantially oil-free aqueous gel comprising a water-soluble humectant, a hydrophilic gelling agent, a specific silicone component and a specific cationic surfactant component. The compositions provide improved oil control along with improved skin feel and residue characteristics together with excellent moisturizing, emolliency, rub-in and absorption characteristics.
摘要翻译：一种基本上无油的含水凝胶形式的护肤组合物，其包含水溶性湿润剂，亲水胶凝剂，特定硅氧烷组分和特定的阳离子表面活性剂组分。组合物提供改善的油控制以及改善的皮肤感觉和残留特性以及优异的保湿，润肤，擦洗和吸收特性。

7. 发明授权

US5229104A Artificial tanning compositions containing positively charged paucilamellar vesicles 失效
标题翻译：含有正电荷的PAULILICELLARVESES的人造革组合物
公开(公告)号：US5229104A
公开(公告)日：1993-07-20
申请号：US693263
申请日：1991-04-29
申请人： John P. Sottery , George E. Deckner
发明人： John P. Sottery , George E. Deckner
IPC分类号： A61K8/06 , A61K8/00 , A61K8/11 , A61K8/14 , A61K8/25 , A61K8/29 , A61K8/31 , A61K8/33 , A61K8/35 , A61K8/36 , A61K8/37 , A61K8/39 , A61K8/40 , A61K8/41 , A61K8/42 , A61K8/49 , A61K8/60 , A61K8/73 , A61K8/92 , A61Q17/04 , A61Q19/00 , A61Q19/04
CPC分类号： A61Q19/04 , A61K8/14 , A61K8/35 , Y10S514/847 , Y10S514/938
摘要： The present invention relates to oil-in-water emulsion compositions useful for imparting an artificial tan to human skin. These emulsions contain paucilamellar lipid vesicles, i.e. vesicles comprising several concentric lipid bilayers, encapsulating an aqueous dihydroxyacetone solution. The vesicles comprise a polyoxyalkylene alkyl ether, a sterol, a quaternary ammonium compound, and optionally, a non-surface active oil. In further embodiments, these emulsion compositions contain one or more sunscreens, and are also useful for protecting human skin from the harmful effects of sunlight and other sources of ultraviolet radiation. The present invention also relates to methods for preparing these compositions, methods for providing an artificial tan to human skin, and methods for protecting human skin from the harmful effects of ultraviolet radiation.
摘要翻译：本发明涉及用于赋予人皮肤人造棕褐色的水包油型乳液组合物。这些乳剂含有微囊脂质囊泡，即包含几个同心脂双层囊泡囊泡囊泡水溶液。囊泡包含聚氧化烯烷基醚，固醇，季铵化合物和任选的非表面活性油。在另外的实施方案中，这些乳液组合物含有一种或多种防晒剂，并且也可用于保护人的皮肤免受阳光和其它紫外线辐射源的有害影响。本发明还涉及制备这些组合物的方法，用于向人体皮肤提供人造棕褐色的方法，以及用于保护人体皮肤免受紫外线辐射的有害影响的方法。

8. 发明授权

US5219558A Photoprotection compositions having improved substantivity 失效
标题翻译：具有改善的亲和性的光保护组合物
公开(公告)号：US5219558A
公开(公告)日：1993-06-15
申请号：US824965
申请日：1992-01-22
申请人： Frederick W. Woodin, Jr. , George E. Deckner
发明人： Frederick W. Woodin, Jr. , George E. Deckner
CPC分类号： A61Q17/04 , A61K8/06 , A61K8/062 , A61K8/37 , A61K8/8147 , Y10S514/844 , Y10S514/847 , Y10S514/938
摘要： Disclosed are topical compositions having improved substantivity such as improved water-proofing (e.g., resistance to perspiration) and rub-off resistance useful for protecting the skin from the harmful effects of ultraviolet irradiation, such as sunburn and sun-induced premature aging of the skin.
摘要翻译：公开了具有改善的亲和性的局部组合物，例如改善的防水性（例如，耐汗水性）和耐刮擦性，其可用于保护皮肤免受紫外线照射的有害影响，例如晒伤和太阳引起的皮肤过早老化。

9. 发明授权

US4847267A Skin treatment composition and method 失效
标题翻译：皮肤处理组成和方法
公开(公告)号：US4847267A
公开(公告)日：1989-07-11
申请号：US939388
申请日：1986-12-08
申请人： George E. Deckner , Arthur C. W. Georgalas
发明人： George E. Deckner , Arthur C. W. Georgalas
IPC分类号： A61K8/49 , A61Q17/00 , A61Q17/04
CPC分类号： A61Q17/04 , A61K8/4926 , A61K8/498 , A61Q17/00 , Y10S514/917
摘要： Skin treatment compositions are provided which inhibit generation of free radicals in the skin and which include 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid, 6-ethoxy-1,2-dihydro-2,2,4-trimethyl quinoline or mixture thereof, and optionally a stabilizer for the 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid which is monoethanolamine sulfite or sodium bisulfite.
摘要翻译：提供了抑制皮肤中自由基产生的皮肤治疗组合物，其包括6-羟基-2,5,7,8-四甲基苯并二氢吡喃-2-羧酸，6-乙氧基-1,2-二氢-2,2， 4-三甲基喹啉或其混合物，以及任选的用于作为亚硫酸单乙醇胺或亚硫酸氢钠的6-羟基-2,5,7,8-四甲基苯并二氢吡喃-2-羧酸的稳定剂。

10. 发明授权

US4690815A Method for testing skin for presence of moisturizer 失效
标题翻译：皮肤保湿剂的存在方法
公开(公告)号：US4690815A
公开(公告)日：1987-09-01
申请号：US765632
申请日：1985-08-15
申请人： George E. Deckner
发明人： George E. Deckner
IPC分类号： G01N33/50 , G01N33/52 , C12Q1/58 , G01N33/48 , G01N33/62 , G01N33/68
CPC分类号： G01N33/521 , G01N33/5014 , Y10S435/805 , Y10T436/144444
摘要： A method for testing skin for presence of moisturizing substances is provided which method includes the steps of applying to the skin a moisturizer formulation which includes protein, urea and/or glucose and/or other reducing sugar such as fructose all of which bind with water and form a film or coating on the skin which inhibits moisture loss from the skin, and subsequently testing the skin for the presence of protein, urea and/or glucose and/or other reducing sugar remaining on the skin which is directly correlated to the amount of moisturizer formulation remaining on the skin. When it is determined through the testing that there has been at least a predetermined loss of protein, urea and/or glucose or other reducing sugar, additional moisturizer is then applied to the skin.
摘要翻译：提供了一种用于测试皮肤存在保湿物质的方法，该方法包括以下步骤：向皮肤施用包含蛋白质，尿素和/或葡萄糖和/或其它还原糖如果糖的所有这些都与水结合的保湿剂制剂，以及在皮肤上形成膜或涂层，其抑制水分从皮肤中的损失，随后测试皮肤中残留在皮肤上的蛋白质，尿素和/或其它还原糖的存在，其与皮肤的量保湿剂配方保留在皮肤上。当通过测试确定蛋白质，尿素和/或葡萄糖或其它还原糖至少存在预定的损失时，然后将另外的保湿剂施加到皮肤上。

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