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    • 2. 发明授权
    • Polystyrene sulfonate-containing gel preparation
    • 含聚苯乙烯磺酸盐的凝胶制剂
    • US06703013B1
    • 2004-03-09
    • US09508539
    • 2000-04-05
    • Hideaki NinomiyaMasahiro NakajimaToshiyuki KouzakiMasaki AndoFumio Higuchi
    • Hideaki NinomiyaMasahiro NakajimaToshiyuki KouzakiMasaki AndoFumio Higuchi
    • A61K3774
    • A61K9/006A61K9/06A61K31/795Y10S514/944
    • The invention relates to a polystyrene sulfonate-containing gel preparation for therapy of hyperpotassemia, wherein the particle size of polystyrene sulfonate is controlled within the range of at least 5-100 &mgr;m, the viscosity of its solution before gelation is adjusted depending on the particle size by adding a thickening agent, and the polystyrene sulfonate particles after gelation is uniformly dispersed therein. More preferably, a water-displacing agent is contained, whereby the amount of water in the preparation is reduced. This gel preparation does not cause a sense of foreign matter or a sense of roughness in the oral cavity upon ingestion and intake, thus making it unnecessary to drink water for ingestion, and further its water content is low, so that control of water intake is made easy, even in the case of a patient with renal insufficiency who is subjecting to restriction in intake of water to significant improve the quality of life of the patient.
    • 本发明涉及一种用于治疗高钾血症的聚苯乙烯磺酸盐凝胶制剂,其中聚苯乙烯磺酸盐的粒径控制在至少5-100μm的范围内,凝胶化前溶液的粘度根据粒径 通过添加增稠剂,凝胶化后的聚苯乙烯磺酸酯粒子均匀分散。 更优选含有取代剂,由此减少制剂中的水量。 这种凝胶制剂在摄入和摄入时不会引起口腔感和异味,因此不必饮用水摄取,进一步其含水量低,从而控制摄入水量 即使在患有肾功能不全的患者进行限制摄入水以显着改善患者的生活质量的情况下也是容易的。
    • 3. 发明授权
    • Multi-spindle head-replacing machine tool
    • 多主轴头置换机床
    • US4776081A
    • 1988-10-11
    • US110660
    • 1987-10-20
    • Hiromu OkunishiHitoshi HashimotoTakeshi IshibashiFumio HiguchiShinichi KuriyamaHiroshi Yamamoto
    • Hiromu OkunishiHitoshi HashimotoTakeshi IshibashiFumio HiguchiShinichi KuriyamaHiroshi Yamamoto
    • B23B39/16B23Q3/157
    • B23Q3/157B23Q2003/1558Y10T483/13Y10T483/134Y10T483/1738Y10T483/1783Y10T483/179Y10T483/1873
    • In multi-spindle head-replacing type machine tool comprising a machining unit disposed on a base for advancing and retreating movements between an original position and a machining position, a first annular guide rail including a movable rail integral with the machining unit and a stationary rail to surround the machining unit which is located in the original position, a second annular guide rail disposed concentrically with and at a place axially offset from the first guide rail, a plurality of multi-spindle heads travellably carried on each of the first and second guide rails, first and second index mechanisms releasably connected respectively to the multi-spindle heads on the first and second guide rails for driving such multi-spindle heads for angular displacement, and an elevator mechanism disposed sideways from the first and second guide rails at a place offset from the movable rail for providing replacement of the multi-spindle heads between the first and second guide rails, a part of the stationary rail of the first guide rail and a part of the second guide rail are divided as lift rails in a circular arc at a place corresponding to the elevator mechanism, respectively, and the elevator mechanism comprises an elevator connected to each of the lift rails of the first and second guide rails, and lift-drive means connected to the elevator which is to be raised and lowered between the first and second guide rails.
    • 在多轴头置换型机床中,包括设置在基座上的加工单元,用于在原始位置和加工位置之间前进和后退运动,第一环形导轨包括与加工单元一体的活动导轨和固定导轨 围绕位于原始位置的加工单元,与所述第一导轨轴向偏置的位置同心且位于与所述第一导轨轴向偏移的位置设置的第二环形导轨,多个多主轴头可移动地承载在所述第一和第二导向件中的每一个上 轨道,分别与第一和第二导轨上的多主轴头可释放地连接以驱动用于角位移的多主轴头的第一和第二索引机构,以及在第一和第二导轨的一个位置处侧向设置的升降机构 偏移于可移动导轨,用于在第一和第二导轨之间提供多主轴头的更换 第一导轨的固定轨道的一部分和第二导轨的一部分分别作为与电梯机构对应的位置处的圆弧中的升降轨道分开,并且电梯机构包括连接到每个 第一和第二导轨的升降轨,以及连接到升降机的提升驱动装置,其将在第一和第二导轨之间升高和降低。