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1. 发明授权

US08271068B2 Method for dynamic road mapping 有权
标题翻译：动态路线图的方法
公开(公告)号：US08271068B2
公开(公告)日：2012-09-18
申请号：US12243224
申请日：2008-10-01
申请人： Ali Khamene , Frederik Bender , Wolfgang Wein
发明人： Ali Khamene , Frederik Bender , Wolfgang Wein
IPC分类号： A61B5/05
CPC分类号： A61B5/06 , A61B5/061 , A61B5/062 , A61B6/12 , A61B6/481 , A61B6/504 , G06T7/74 , G06T7/75 , G06T2207/10121 , G06T2207/30021 , G06T2207/30101
摘要： A method of determining a three-dimensional (3D) position of a catheter tip includes: compensating a 2D position of the tip of the catheter for respiratory motion to generate a compensated 2D catheter position, generating weighted sample points around the compensated 2D catheter position, determining correspondent points of the weighted sample points in a 3D image, computing a weighted mean and a weighted covariance of each correspondent point, and determining the 3D position of the catheter tip in the 3D image from a fusion of the weighted means and weighted covariances.
摘要翻译：确定导管尖端的三维（3D）位置的方法包括：补偿用于呼吸运动的导管尖端的2D位置以产生补偿的2D导管位置，在补偿的2D导管位置周围产生加权采样点，确定3D图像中的加权采样点的相应点，计算每个对应点的加权平均值和加权协方差，以及从加权平均值和加权协方差的融合确定3D图像中导管尖端的3D位置。

2. 发明申请

US20130190615A1 System for 3D Visualization of Radio-Opaque Embolic Materials Using X-ray Imaging 审中-公开
标题翻译：使用X射线成像的无线电不透明栓塞材料的3D可视化系统
公开(公告)号：US20130190615A1
公开(公告)日：2013-07-25
申请号：US13690247
申请日：2012-11-30
申请人： Kevin Royalty , Frederik Bender , Maria Lydia Sarmiento
发明人： Kevin Royalty , Frederik Bender , Maria Lydia Sarmiento
IPC分类号： A61B6/00 , A61B6/02
摘要： An image data processor automatically identifies individual picture elements representing embolic material in first and second 2D X-ray images in response to a luminance intensity value of the picture elements exceeding a threshold. The image data processor also automatically identifies individual volume elements in a 3D X-ray image dataset corresponding to the identified individual picture elements by, for an individual picture element, detecting intersection of a projected line with one or more volume elements in the 3D image dataset representing vessels. The projected line substantially passes from the individual picture element to an X-ray radiation source. The display processor initiates generation of data representing a display image showing the identified individual volume elements representing embolic material, with enhanced visualization.
摘要翻译：图像数据处理器响应于图像元素的亮度强度值超过阈值，自动识别表示第一和第二2D X射线图像中的栓塞材料的各个图像元素。图像数据处理器还通过针对单个图像元素来检测与所识别的各个图像元素相对应的3D X射线图像数据集中的各个体积元素，以检测投影线与3D图像数据集中的一个或多个体积元素的相交代表船只。投射线基本上从各个像素传递到X射线辐射源。显示处理器启动生成表示显示图像的数据的数据，该显示图像示出了具有增强的可视化的表示栓塞材料的所识别的各个体积元素。

3. 发明申请

US20090088632A1 Method for Dynamic Road Mapping 有权
标题翻译：动态路线图的方法
公开(公告)号：US20090088632A1
公开(公告)日：2009-04-02
申请号：US12243224
申请日：2008-10-01
申请人： Ali Khamene , Frederik Bender , Wolfgang Wein
发明人： Ali Khamene , Frederik Bender , Wolfgang Wein
IPC分类号： A61B5/05
CPC分类号： A61B5/06 , A61B5/061 , A61B5/062 , A61B6/12 , A61B6/481 , A61B6/504 , G06T7/74 , G06T7/75 , G06T2207/10121 , G06T2207/30021 , G06T2207/30101
摘要： A method of determining a three-dimensional (3D) position of a catheter tip includes: compensating a 2D position of the tip of the catheter for respiratory motion to generate a compensated 2D catheter position, generating weighted sample points around the compensated 2D catheter position, determining correspondent points of the weighted sample points in a 3D image, computing a weighted mean and a weighted covariance of each correspondent point, and determining the 3D position of the catheter tip in the 3D image from a fusion of the weighted means and weighted covariances.
摘要翻译：确定导管尖端的三维（3D）位置的方法包括：补偿用于呼吸运动的导管尖端的2D位置以产生补偿的2D导管位置，在补偿的2D导管位置周围产生加权采样点，确定3D图像中的加权采样点的相应点，计算每个对应点的加权平均值和加权协方差，以及从加权平均值和加权协方差的融合确定3D图像中导管尖端的3D位置。

4. 发明申请

US20120065498A1 APPARATUS AND METHOD FOR MINIMALLY INVASIVE THERAPY OF MITRAL REGURGITATION 审中-公开
标题翻译：微生物注射治疗微生物治疗的装置及方法
公开(公告)号：US20120065498A1
公开(公告)日：2012-03-15
申请号：US12881925
申请日：2010-09-14
申请人： Thomas Redel , Michael Maschke , Frederik Bender
发明人： Thomas Redel , Michael Maschke , Frederik Bender
IPC分类号： A61B5/05 , A61B8/00
CPC分类号： A61B8/12 , A61B8/0883 , A61B8/488
摘要： A system and method of treatment of mitral valve insufficiency using an implantable medical device is described. The system uses a C-arm X-ray device configured to produce computed-tomographic (CT)-like images, and to superimpose the CT-like images on a fluoroscopic image taken with the same X-ray device as a part of the treatment procedure. The fluoroscopic images are used to guide a catheter in the patient so as to place the medical device in a proper position. The efficacy of the procedure may be assessed using a non-invasive or minimally invasive acoustic imaging technique.
摘要翻译：描述了使用可植入医疗装置治疗二尖瓣关闭不全的系统和方法。该系统使用配置为产生计算机断层摄影（CT）的图像的C臂X射线装置，并且将CT样图像叠加在作为治疗的一部分的相同X射线装置拍摄的荧光镜图像上程序。透视图像用于引导患者中的导管，以将医疗装置放置在适当的位置。可以使用非侵入性或微创声学成像技术来评估该程序的功效。

5. 发明授权

US08755587B2 Method for providing a 3D image data record of a physiological object with a metal object therein 有权
标题翻译：用于在其中提供具有金属物体的生理对象的3D图像数据记录的方法
公开(公告)号：US08755587B2
公开(公告)日：2014-06-17
申请号：US13407793
申请日：2012-02-29
申请人： Frederik Bender , Kevin Royalty
发明人： Frederik Bender , Kevin Royalty
IPC分类号： G06K9/00
CPC分类号： A61B6/583 , A61B6/02 , A61B6/4014 , A61B10/0233 , A61B90/36 , A61B2090/367 , A61B2090/376
摘要： A method for providing a 3D image data record of a physiological object with a metal object therein is proposed. To enable an image of the metal object in the physiological object, for instance a biopsy needle in a human patient to be recorded as a 3D image in this patient, two 2D x-ray images of the patient are obtained with the needle with the aid of a biplane x-ray system, and back projection allows a 3D image data record to be generated, which is then subject to a filtering with a gray-scale value window. After filtering, information relating to the position and shape of the metal object in space is obtained. The thus obtained first 3D image data record can be combined with another 3D image data record, in particular with a 3D image data record of the patient without the metal object obtained with the same biplane x-ray system.
摘要翻译：提出了一种用于在其中提供具有金属物体的生理对象的3D图像数据记录的方法。为了使生理对象中的金属物体的图像，例如人类患者中的活检针被记录为该患者中的3D图像，可以用针来帮助患者获得患者的两个2D X射线图像的双平面x射线系统，并且背投影允许生成3D图像数据记录，然后进行灰阶值窗口的滤波。过滤后，获得与空间中的金属物体的位置和形状有关的信息。如此获得的第一3D图像数据记录可以与另一3D图像数据记录组合，特别是与没有使用相同的双平面x射线系统获得的金属物体的患者的3D图像数据记录组合。

6. 发明申请

US20120224761A1 Method for providing a 3D image data record of a physiological object with a metal object therein 有权
标题翻译：用于在其中提供具有金属物体的生理对象的3D图像数据记录的方法
公开(公告)号：US20120224761A1
公开(公告)日：2012-09-06
申请号：US13407793
申请日：2012-02-29
申请人： Frederik Bender , Kevin Royalty
发明人： Frederik Bender , Kevin Royalty
IPC分类号： G06K9/00
CPC分类号： A61B6/583 , A61B6/02 , A61B6/4014 , A61B10/0233 , A61B90/36 , A61B2090/367 , A61B2090/376
摘要： A method for providing a 3D image data record of a physiological object with a metal object therein is proposed. To enable an image of the metal object in the physiological object, for instance a biopsy needle in a human patient to be recorded as a 3D image in this patient, two 2D x-ray images of the patient are obtained with the needle with the aid of a biplane x-ray system, and back projection allows a 3D image data record to be generated, which is then subject to a filtering with a gray-scale value window. After filtering, information relating to the position and shape of the metal object in space is obtained. The thus obtained first 3D image data record can be combined with another 3D image data record, in particular with a 3D image data record of the patient without the metal object obtained with the same biplane x-ray system.
摘要翻译：提出了一种用于在其中提供具有金属物体的生理对象的3D图像数据记录的方法。为了使生理对象中的金属物体的图像，例如人类患者中的活检针被记录为该患者中的3D图像，可以用针来帮助患者获得患者的两个2D X射线图像的双平面x射线系统，并且背投影允许生成3D图像数据记录，然后进行灰阶值窗口的滤波。过滤后，获得与空间中的金属物体的位置和形状有关的信息。如此获得的第一3D图像数据记录可以与另一3D图像数据记录组合，特别是与没有使用相同的双平面x射线系统获得的金属物体的患者的3D图像数据记录组合。

7. 发明申请

US20130197354A1 MINIMALLY INVASIVE TREATMENT OF MITRAL REGURGITATION 审中-公开
标题翻译：微生物免疫治疗麻醉药
公开(公告)号：US20130197354A1
公开(公告)日：2013-08-01
申请号：US13361552
申请日：2012-01-30
申请人： Michael Maschke , Frederik Bender , Thomas Redel
发明人： Michael Maschke , Frederik Bender , Thomas Redel
IPC分类号： A61B6/02 , A61F2/24 , A61B8/02 , A61M25/01 , A61B6/12 , A61B6/03
CPC分类号： A61B6/03 , A61B6/12 , A61B6/481 , A61B6/487 , A61B6/503 , A61B6/504 , A61B8/06 , A61B8/0883 , A61F2/2442
摘要： A method of guiding a catheter during a treatment procedure includes acquiring scan data of a patient volume in position for the treatment procedure, registering volume data of the patient volume to the scan data, acquiring fluoroscopic data for the patient volume during the treatment procedure, and generating a volume representation of the fluoroscopic data during the treatment procedure. Generating the volume representation includes superimposing the fluoroscopic data on the volume data based on the registering. The volume representation of the fluoroscopic data is displayed, the volume representation showing a position of a mitral valve clip carried by the catheter relative to the patient volume.
摘要翻译：一种在治疗过程中引导导管的方法包括：获取用于治疗过程的位置的患者体积的扫描数据，将患者体积的体积数据记录到扫描数据，在治疗过程期间获取患者体积的透视数据;以及在处理过程中产生荧光透视数据的体积表示。产生音量表示包括基于注册将荧光透视数据叠加在音量数据上。显示荧光透视数据的体积表示，体积表示显示由导管承载的二尖瓣夹具相对于患者体积的位置。

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