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1. 发明申请

US20090168052A1 SYSTEM AND METHOD FOR IMPROVED BIODETECTION 有权
标题翻译：改进生物防治的系统和方法
公开(公告)号：US20090168052A1
公开(公告)日：2009-07-02
申请号：US11966332
申请日：2007-12-28
申请人： Michael Craig Burrell , Frank Mondello , Tracy Lynn Paxon , William Scott Sutherland , Christopher Montalbano , Gregory Montalbano , Aaron Klein
发明人： Michael Craig Burrell , Frank Mondello , Tracy Lynn Paxon , William Scott Sutherland , Christopher Montalbano , Gregory Montalbano , Aaron Klein
IPC分类号： G01N1/00
CPC分类号： G01N21/65 , G01N1/405 , G01N21/658
摘要： A portable substance identification system and method are configured to identify at least one detection target faster and with greater accuracy than is possible using prior substance identification systems and/or prior substance identification techniques. An embodiment of the portable substance identification system includes a portable substance identification device containing a Raman spectrometer, and a collection stem that includes a dry collector. One or more reservoirs for a liquid medium and /or a reagent can be formed in a cartridge that is configured to couple with a portable substance identification device. The cartridge has a chamber in which the reagent, liquid medium, and a detection target picked up by the dry collector are mixed. A magnet, positioned at a slant angle, can be used to form at least one pellet of aggregated magnetic particles within a pellet forming area of the chamber. The pellet is formed to maximize its surface area.
摘要翻译：便携式物质识别系统和方法被配置为比使用先前物质识别系统和/或先前物质识别技术更快，更准确地识别至少一个检测目标。便携式物质识别系统的实施例包括含有拉曼光谱仪的便携式物质识别装置和包括干燥收集器的收集杆。用于液体介质和/或试剂的一个或多个储存器可以形成在配置成与便携式物质识别装置联接的盒中。该盒具有混合由干燥收集器拾取的试剂，液体介质和检测对象的室。以倾斜角定位的磁体可以用于在腔室的颗粒形成区域内形成至少一个聚集的磁性颗粒颗粒。形成颗粒使其表面积最大化。

2. 发明授权

US07847932B2 System and method for improved biodetection 有权
标题翻译：改进生物检测的系统和方法
公开(公告)号：US07847932B2
公开(公告)日：2010-12-07
申请号：US11966279
申请日：2007-12-28
申请人： Michael Craig Burrell , Frank Mondello , Tracy Lynn Paxon , William Scott Sutherland , Christopher Montalbano , Gregory Montalbano , Aaron Klein
发明人： Michael Craig Burrell , Frank Mondello , Tracy Lynn Paxon , William Scott Sutherland , Christopher Montalbano , Gregory Montalbano , Aaron Klein
IPC分类号： G01J3/44
CPC分类号： G01N21/658 , G01N2021/651 , G01N2201/0221
摘要： Portable substance identification system and method are configured to identify at least one detection target faster and with greater accuracy than is possible using prior substance identification systems and/or prior substance identification techniques. An embodiment of the portable substance identification system includes a portable substance identification device containing a Raman spectrometer, and a collection stem that includes a collector. One or more reservoirs for a liquid medium and/or at least one reagent can be formed in the collection stem. The cartridge can include a chamber in which the reagents, liquid medium, and at least one detection target picked up by the collector are mixed. A magnet, positioned at a slant angle, can be used to form at least one pellet of aggregated magnetic particles within a pellet forming area of the chamber. The pellet is formed to maximize its surface area.
摘要翻译：便携式物质识别系统和方法配置成比使用先前物质识别系统和/或先前物质识别技术更快，更准确地识别至少一个检测目标。便携式物质识别系统的实施例包括包含拉曼光谱仪的便携式物质识别装置和包括收集器的收集杆。用于液体介质和/或至少一种试剂的一个或多个储存器可以形成在收集杆中。药筒可以包括其中混合有由试剂，液体介质和由收集器拾取的至少一个检测目标的室。以倾斜角定位的磁体可以用于在腔室的颗粒形成区域内形成至少一个聚集的磁性颗粒颗粒。形成颗粒使其表面积最大化。

3. 发明申请

US20090168592A1 AGITATOR FOR PORTABLE SUBSTANCE IDENTIFICATION SYSTEM AND METHOD 审中-公开
标题翻译：用于便携式物质识别系统和方法的搅拌器
公开(公告)号：US20090168592A1
公开(公告)日：2009-07-02
申请号：US11966395
申请日：2007-12-28
申请人： Michael Craig Burrell , Frank Mondello , Tracy Lynn Paxon , William Scott Sutherland , Christopher Montalbano , Gregory Montalbano , Aaron Klein
发明人： Michael Craig Burrell , Frank Mondello , Tracy Lynn Paxon , William Scott Sutherland , Christopher Montalbano , Gregory Montalbano , Aaron Klein
IPC分类号： B01F13/00
CPC分类号： B01F15/0205 , B01F13/002 , B01F15/0206 , B01F15/0226 , G01N35/0098 , G01N2035/00465
摘要： A substance identification system is configured to identify at least one detection target faster and with greater accuracy than is possible using prior substance identification systems and/or prior substance identification techniques. An agitator for a portable substance identification system includes a body. The body has a receptacle formed therein. The receptacle is configured to receive a cartridge. The cartridge has a chamber formed therein and a collector of a collection stem coupled with the chamber.
摘要翻译：物质识别系统配置成比使用先前物质识别系统和/或先前物质识别技术更快，更准确地识别至少一个检测目标。用于便携式物质识别系统的搅拌器包括主体。本体具有形成在其中的容器。容器被配置成接收盒。盒具有形成在其中的腔室和与腔室联接的收集杆的收集器。

4. 发明申请

US20090168058A1 SYSTEM AND METHOD FOR IMPROVED BIODETECTION 有权
标题翻译：改进生物防治的系统和方法
公开(公告)号：US20090168058A1
公开(公告)日：2009-07-02
申请号：US11966279
申请日：2007-12-28
申请人： Michael Craig Burrell , Frank Mondello , Tracy Lynn Paxon , William Scott Sutherland , Christopher Montalbano , Gregory Montalbano , Aaron Klein
发明人： Michael Craig Burrell , Frank Mondello , Tracy Lynn Paxon , William Scott Sutherland , Christopher Montalbano , Gregory Montalbano , Aaron Klein
IPC分类号： G01J3/44
CPC分类号： G01N21/658 , G01N2021/651 , G01N2201/0221
摘要： Portable substance identification system and method are configured to identify at least one detection target faster and with greater accuracy than is possible using prior substance identification systems and/or prior substance identification techniques. An embodiment of the portable substance identification system includes a portable substance identification device containing a Raman spectrometer, and a collection stem that includes a collector. One or more reservoirs for a liquid medium and/or at least one reagent can be formed in the collection stem. The cartridge can include a chamber in which the reagents, liquid medium, and at least one detection target picked up by the collector are mixed. A magnet, positioned at a slant angle, can be used to form at least one pellet of aggregated magnetic particles within a pellet forming area of the chamber. The pellet is formed to maximize its surface area.
摘要翻译：便携式物质识别系统和方法配置成比使用先前物质识别系统和/或先前物质识别技术更快，更准确地识别至少一个检测目标。便携式物质识别系统的实施例包括包含拉曼光谱仪的便携式物质识别装置和包括收集器的收集杆。用于液体介质和/或至少一种试剂的一个或多个储存器可以形成在收集杆中。药筒可以包括其中混合有由试剂，液体介质和由收集器拾取的至少一个检测目标的室。以倾斜角定位的磁体可以用于在腔室的颗粒形成区域内形成至少一个聚集的磁性颗粒颗粒。形成颗粒使其表面积最大化。

5. 发明申请

US20070058165A1 Raman-active lateral flow device and methods of detection and making 有权
标题翻译：拉曼主动横流装置及其检测方法
公开(公告)号：US20070058165A1
公开(公告)日：2007-03-15
申请号：US11257164
申请日：2005-10-24
申请人： Frank Mondello
发明人： Frank Mondello
IPC分类号： G01J3/44
CPC分类号： G01N21/65 , G01N21/658
摘要： A lateral flow device is disclosed. The lateral flow device includes a substrate having a flow path and a detection zone disposed along the flow path. The detection zone includes an immobilized target-binding moiety directed against a target of a Raman-active complex. A portion of the detection zone has a dimension that is less than another dimension of the lateral flow device upflow from the detection zone or a first region of the detection zone has a chemical difference from a second region of the detection zone. Also disclosed are methods of conducting a lateral flow assay and methods of making a lateral flow device.
摘要翻译：公开了一种侧流装置。横向流动装置包括具有沿着流动路径设置的流路和检测区域的基板。检测区包括针对拉曼活性复合物的靶的固定的靶结合部分。检测区域的一部分具有小于横向流动装置从检测区向上流动的另一维度的尺寸，或者检测区域的第一区域与检测区域的第二区域具有化学差异。还公开了进行侧流测定的方法和制造侧流装置的方法。

6. 发明申请

US20060216697A1 Method of separating unattached Raman-active tag from bioassay or other reaction mixture 审中-公开
标题翻译：从生物测定或其他反应混合物中分离未附着的拉曼活性标签的方法
公开(公告)号：US20060216697A1
公开(公告)日：2006-09-28
申请号：US11087419
申请日：2005-03-24
申请人： Frank Mondello , Michael Burrell
发明人： Frank Mondello , Michael Burrell
IPC分类号： C12Q1/70 , C12Q1/68 , G01N33/551
CPC分类号： G01N33/5306 , B03C1/30 , B82Y25/00 , G01N21/65 , G01N21/658 , G01N33/58 , H01F1/0054
摘要： A super-paramagnetic Raman-active complex that includes a Raman-active tag attached to a target and a super-paramagnetic bead attached to the target is disclosed. A method of separating a Raman or surface enhanced Raman-active tag unattached to a target from a Raman-active complex is also disclosed. The Raman-active complex includes a Raman-active tag attached to a target. The method includes providing a mixture that includes at least one Raman-active tag unattached to a target and at least one super-paramagnetic Raman-active complex; and applying a magnetic field to the mixture.
摘要翻译：公开了一种超顺磁拉曼活性复合物，其包括附着于靶的拉曼活性标签和附着于靶的超顺磁珠。还公开了从拉曼活性复合物分离未附着于靶的拉曼或表面增强拉曼活性标签的方法。拉曼活性复合物包括附着于靶的拉曼活性标签。该方法包括提供一种混合物，该混合物包括至少一个未附着于靶标的拉曼活性标签和至少一种超顺磁性拉曼活性复合物; 并向混合物施加磁场。

7. 发明申请

US20070181508A1 Photocatalytic fluid purification systems and methods for purifying a fluid 审中-公开
标题翻译：光催化流体净化系统和净化流体的方法
公开(公告)号：US20070181508A1
公开(公告)日：2007-08-09
申请号：US11479329
申请日：2006-06-30
申请人： John Gui , John Lemmon , Larry Lewis , Anil Duggal , Venkatesan Manivannan , Jie Liu , Frank Mondello
发明人： John Gui , John Lemmon , Larry Lewis , Anil Duggal , Venkatesan Manivannan , Jie Liu , Frank Mondello
IPC分类号： C02F1/32
CPC分类号： A61L9/18 , A61L9/205
摘要： A conformable air purification system and methods generally includes optically coupling an active coating comprising a photocatalyst material with a flexible organic light emitting device (OLED) and configuring the flexible media into a desired shape that defines the fluid passageways of then system. The organic light emitting device can be selected to emit light in the visible range when low band gap photocatalyst materials are employed.
摘要翻译：适合的空气净化系统和方法通常包括将包含光催化剂材料的活性涂层与柔性有机发光器件（OLED）光学耦合，并将柔性介质构造成限定当时系统的流体通道的期望形状。当使用低带隙光催化剂材料时，可以选择有机发光器件在可见光范围内发光。

8. 发明申请

US20060134806A1 Method of separating unattached Raman-active tag from bioassay or other reaction mixture 审中-公开
标题翻译：从生物测定或其他反应混合物中分离未附着的拉曼活性标签的方法
公开(公告)号：US20060134806A1
公开(公告)日：2006-06-22
申请号：US11018512
申请日：2004-12-20
申请人： Frank Mondello
发明人： Frank Mondello
IPC分类号： G01N33/551
CPC分类号： G01N33/585
摘要： A method of separating a Raman-active tag unattached to a target from a Raman-active complex is disclosed. The Raman-active complex includes a Raman-active tag attached to a target. The method includes providing a mixture including at least one Raman-active tag unattached to a target and at least one Raman-active complex; and passing the mixture through a porous membrane.
摘要翻译：公开了一种从拉曼活性复合物分离未连接到靶的拉曼活性标签的方法。拉曼活性复合物包括附着于靶的拉曼活性标签。该方法包括提供包含至少一个未附着于靶标的拉曼活性标签和至少一种拉曼活性复合物的混合物; 并使混合物通过多孔膜。

9. 发明申请

US20090169433A1 SYSTEM FOR IMPROVED BIODETECTION 审中-公开
标题翻译：改进生物保护系统
公开(公告)号：US20090169433A1
公开(公告)日：2009-07-02
申请号：US11966378
申请日：2007-12-28
申请人： Sankaran Kumar , Christopher Crowley , Erik Edmund Magnuson , Michael Craig Burrell , Frank Mondello , Tracy Lynn Paxon
发明人： Sankaran Kumar , Christopher Crowley , Erik Edmund Magnuson , Michael Craig Burrell , Frank Mondello , Tracy Lynn Paxon
IPC分类号： G01N21/31
CPC分类号： G01N21/658 , G01N2021/651
摘要： A substance identification system is configured to identify at least one detection target faster and with greater accuracy than is possible using prior substance identification systems and/or prior substance identification techniques. A chamber includes a pellet forming area having a predetermined geometry that is configured to maximize a ratio of a pellet surface area to a pellet volume. A magnet is positioned on one side of the chamber and configured to form a pellet of aggregated magnetic particles in the pellet forming area. A laser source is positioned on the same side of the chamber as the magnet and configured to illuminate the pellet, when the pellet is formed in the pellet forming area.
摘要翻译：物质识别系统配置成比使用先前物质识别系统和/或先前物质识别技术更快，更准确地识别至少一个检测目标。腔室包括具有预定几何形状的丸粒形成区域，其被构造成使球团表面积与球团体积的比例最大化。磁体位于室的一侧，并且构造成在颗粒形成区域中形成聚集的磁性颗粒的颗粒。当颗粒形成在颗粒形成区域中时，激光源被定位在与磁体相同的腔室的相同侧上并被配置为照射颗粒。

10. 发明申请

US20070090926A1 Chemical and biological sensors, systems and methods based on radio frequency identification 审中-公开
标题翻译：基于射频识别的化学和生物传感器，系统和方法
公开(公告)号：US20070090926A1
公开(公告)日：2007-04-26
申请号：US11259710
申请日：2005-10-26
申请人： Radislav Potyrailo , Kenneth Welles , John Gui , Amy Smentkowski , Frank Mondello
发明人： Radislav Potyrailo , Kenneth Welles , John Gui , Amy Smentkowski , Frank Mondello
IPC分类号： H04Q5/22 , G01R27/00
CPC分类号： G06K19/07749 , G01N27/3275 , G01N27/3278 , G06K19/0717
摘要： Embodiments of the invention include a wireless sensor, such as an RFID tag, that includes a substrate, an antenna disposed on the substrate, and an environmentally sensitive sensor material disposed over at least a portion of said substrate. Other embodiments an RFID tag and at least one antibody coupled to the RFID tag. The RFID tag includes a substrate, circuitry disposed on the substrate, and an antenna coupled to the substrate. The at least one antibody is capable of affecting the signals emanating from the RFID tag. Further embodiments include a detection system that includes a reader. Yet other embodiments include a method for detecting specific analytes. The method includes providing an RFID tag which emanates a first signal having a first frequency, and enabling the RFID tag to emanate a second signal having a second frequency upon attraction of a specific analyte to the RFID tag.
摘要翻译：本发明的实施例包括诸如RFID标签的无线传感器，其包括基板，设置在基板上的天线以及设置在所述基板的至少一部分上的对环境敏感的传感器材料。其他实施例是RFID标签和耦合到RFID标签的至少一个抗体。 RFID标签包括衬底，设置在衬底上的电路和耦合到衬底的天线。所述至少一种抗体能够影响从RFID标签发出的信号。另外的实施例包括包括读取器的检测系统。其他实施方案包括用于检测特定分析物的方法。该方法包括提供发射具有第一频率的第一信号的RFID标签，并且使RFID标签在将特定分析物吸引到RFID标签时能够发出具有第二频率的第二信号。

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