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1. 发明授权

US07996062B2 Double-contrast technique for MRI-guided vascular interventions 有权
标题翻译：用于MRI引导血管干预的双重对比技术
公开(公告)号：US07996062B2
公开(公告)日：2011-08-09
申请号：US12577805
申请日：2009-10-13
申请人： Frank K. Wacker , Jeffrey L. Duerk , Jonathan S. Lewin , Robbert M. Maes
发明人： Frank K. Wacker , Jeffrey L. Duerk , Jonathan S. Lewin , Robbert M. Maes
IPC分类号： A61B5/05
CPC分类号： G01R33/5601 , G01R33/286
摘要： Methods for confirming location of a catheter tip relative to a targeted location in a blood vessel of a subject and improving visualization of the blood vessels downstream of the catheter tip are provided. The methods comprise acquiring and displaying a first modified MR image of the subject's blood vessels between an insertion site for the catheter and the targeted location; acquiring and displaying a sequence of modified MR images of the blood vessels to monitor advancement of an inserted catheter from the insertion site to an intraluminal stop site at or near the targeted location; delivering a bolus of a magnetic resonance contrast agent through the tip of the catheter and to the intraluminal stop site, wherein the magnetic contrast agent alters the first modified MR image of the subject's blood vessels; acquiring and displaying an updated second MR modified image of the blood vessels at and downstream of the tip of the catheter. Systems and computer readable medium storing computer executable instructions operable to perform computer executable aspects of the present methods are also provided.
摘要翻译：提供了用于确认导管尖端相对于受试者的血管中的目标位置的位置并改善导管末端下游的血管的可视化的方法。所述方法包括在导管的插入位置和目标位置之间获取和显示受试者的血管的第一修改的MR图像; 获取和显示所述血管的修改的MR图像的序列，以监测插入的导管从所述插入位置到目标位置处或附近的管腔内停止部位的进展; 通过导管的尖端和腔内停止部位递送大量的磁共振造影剂，其中磁性造影剂改变受试者的血管的第一改良的MR图像; 获取和显示在导管末端和下游的血管的更新的第二MR修改图像。还提供了可操作以执行本方法的计算机可执行方面的存储计算机可执行指令的系统和计算机可读介质。

2. 发明申请

US20100106007A1 DOUBLE-CONTRAST TECHNIQUE FOR MRI-GUIDED VASCULAR INTERVENTIONS 有权
标题翻译：用于MRI引导的血管干预的双对比技术
公开(公告)号：US20100106007A1
公开(公告)日：2010-04-29
申请号：US12577805
申请日：2009-10-13
申请人： Frank K. Wacker , Jeffrey L. Duerk , Jonathan S. Lewin , Robbert M. Maes
发明人： Frank K. Wacker , Jeffrey L. Duerk , Jonathan S. Lewin , Robbert M. Maes
IPC分类号： A61B5/055
CPC分类号： G01R33/5601 , G01R33/286
摘要： Methods for confirming location of a catheter tip relative to a targeted location in a blood vessel of a subject and improving visualization of the blood vessels downstream of the catheter tip are provided. The methods comprise acquiring and displaying a first modified MR image of the subject's blood vessels between an insertion site for the catheter and the targeted location; acquiring and displaying a sequence of modified MR images of the blood vessels to monitor advancement of an inserted catheter from the insertion site to an intraluminal stop site at or near the targeted location; delivering a bolus of a magnetic resonance contrast agent through the tip of the catheter and to the intraluminal stop site, wherein the magnetic contrast agent alters the first modified MR image of the subject's blood vessels; acquiring and displaying an updated second MR modified image of the blood vessels at and downstream of the tip of the catheter. Systems and computer readable medium storing computer executable instructions operable to perform computer executable aspects of the present methods are also provided.
摘要翻译：提供了用于确认导管尖端相对于受试者的血管中的目标位置的位置并改善导管末端下游的血管的可视化的方法。所述方法包括在导管的插入位置和目标位置之间获取和显示受试者的血管的第一修改的MR图像; 获取和显示所述血管的修改的MR图像的序列，以监测插入的导管从所述插入位置到目标位置处或附近的管腔内停止部位的进展; 通过导管的尖端和管腔内止血部位输送大量的磁共振造影剂，其中磁性造影剂改变受试者的血管的第一修改的MR图像; 获取和显示在导管末端和下游的血管的更新的第二MR修改图像。还提供了可操作以执行本方法的计算机可执行方面的存储计算机可执行指令的系统和计算机可读介质。

3. 发明授权

US07623903B2 Double contrast technique for MRI-guided vascular interventions 有权
标题翻译：用于MRI引导血管干预的双重对比技术
公开(公告)号：US07623903B2
公开(公告)日：2009-11-24
申请号：US10441235
申请日：2003-05-19
申请人： Frank K. Wacker , Jeffrey L. Duerk , Jonathan S. Lewin , Robbert M. Maes
发明人： Frank K. Wacker , Jeffrey L. Duerk , Jonathan S. Lewin , Robbert M. Maes
IPC分类号： A61B5/05
CPC分类号： G01R33/5601 , G01R33/286
摘要： A method to detect the location of a catheter relative to a targeted location in a blood vessel is provided. One example method includes acquiring and displaying magnetic resonance (MR) images while a first MR contrast agent is present and while the operation of that first MR contrast agent is counter-acted by a second MR contrast agent. Both MR contrast agents may be introduced into a blood vessel by the catheter whose position is to be detected.
摘要翻译：提供了一种用于检测导管相对于血管中的目标位置的位置的方法。一种示例性方法包括在第一MR造影剂存在的同时获取并显示磁共振（MR）图像，同时该第一MR造影剂的操作由第二MR造影剂反作用。可以通过要检测其位置的导管将两个MR造影剂引入血管。

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