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1. 发明授权

US06365637B1 Use of esters or amides of hydroxylated carboxylic acids as solubilizers 有权
标题翻译：使用羟基化羧酸的酯或酰胺作为增溶剂
公开(公告)号：US06365637B1
公开(公告)日：2002-04-02
申请号：US09433548
申请日：1999-11-04
申请人： Michael Zirnstein , Folker Ruchatz , Karl Kolter , Knut Oppenländer
发明人： Michael Zirnstein , Folker Ruchatz , Karl Kolter , Knut Oppenländer
IPC分类号： C07C6966
CPC分类号： A61K8/39 , A23L29/10 , A61K8/45 , A61K8/86 , A61K9/0019 , A61K47/14 , A61K47/18 , A61K47/34 , A61Q17/04 , A61Q19/00 , C07C69/675 , C08G65/3322
摘要： The use of esters or amides of hydroxylated carboxylic acids as solubilizers, particularly for pharmaceutical, cosmetic and food preparations, is described.
摘要翻译：描述了使用羟基化羧酸的酯或酰胺作为增溶剂，特别是用于制药，化妆品和食品制剂。

2. 发明授权

US06497867B2 Use of copolymers of monoethylenically unsaturated carboxylic acids as solubilizers 有权
标题翻译：使用单烯属不饱和羧酸的共聚物作为增溶剂
公开(公告)号：US06497867B2
公开(公告)日：2002-12-24
申请号：US09953683
申请日：2001-09-18
申请人： Helmut Meffert , Axel Sanner , Gunther Berndl , Folker Ruchatz , Karl Kolter , Kurt Heinz Bauer
发明人： Helmut Meffert , Axel Sanner , Gunther Berndl , Folker Ruchatz , Karl Kolter , Kurt Heinz Bauer
IPC分类号： A61K3174
CPC分类号： A61K8/8158 , A61K8/8152 , A61K9/0014 , A61K9/0019 , A61K9/1075 , A61K9/2027 , A61K9/4866 , A61K47/32 , A61Q13/00 , A61Q17/04 , C08F220/04
摘要： The invention relates to the use of copolymers comprising a) 82 to 99.9 mol % of at least one monoethylenically unsaturated C3-C8-carboxylic acid; b) 0.1 to 18 mol % of at least one monomer selected from the group b1) N—C8-C30-alkyl-substituted amides of monoethylenically unsaturated C3-C8-carboxylic acids, b2) N,N—C8-C30-dialkyl-substituted amides of monoethylenically unsaturated C3-C8-carboxylic acids, b3) C8-C30-alkyl esters of monoethylenically unsaturated C3-C8-carboxylic acids; c) 0 to 17.9 mol % of at least one monomer selected from the group of c1) vinyl esters of aliphatic C8-C30-carboxylic acids, c2) C8-C30-alkylvinyl ethers, the mol % data for the individual components adding up to 100%, as solubilizer.
摘要翻译：本发明涉及包含a）82-99.9摩尔％的至少一种单烯属不饱和C 3 -C 8 - 羧酸的共聚物的用途; b）0.1至18摩尔％的至少一种选自b 1）N-C 8 -C 30 烷基取代的单烯属不饱和C3-C8-羧酸的酰胺，b2）单烯属不饱和C3-C8-羧酸的N，N-C8-C30-二烷基取代的酰胺，b3）单烯属不饱和的C 3 -C 30 - 烷基酯 C 3 -C 8 - 羧酸; c）0至17.9mol％的至少一种选自以下的单体：c1）脂族C 8 -C 30羧酸的乙烯基酯，c 2）C 8 -C 30烷基乙烯基醚，mol％数据为各成分加起来可达100％，作为增溶剂。

3. 发明授权

US06525156B1 Styrene-containing popcorn polymers, method for producing same and utilisation 失效
标题翻译：含苯乙烯的爆米花聚合物，其生产方法和利用
公开(公告)号：US06525156B1
公开(公告)日：2003-02-25
申请号：US09959402
申请日：2001-10-24
申请人： Andreas Ernst , Helmut Meffert , Axel Sanner , Stefan Stein , Folker Ruchatz
发明人： Andreas Ernst , Helmut Meffert , Axel Sanner , Stefan Stein , Folker Ruchatz
IPC分类号： C08F21206
CPC分类号： C08F212/04 , B01J20/26 , B01J39/20 , B01J41/14
摘要： Insoluble, only slightly swellable popcorn polymers containing a) from 50 to 99% by weight of styrene and/or at least one monounsaturated styrene derivative, b) from 0.1 to 40% by weight of at least one N-vinyllactam or N-vinylamine and c) from 0.1 to 10% by weight of at least one difunctional crosslinking component, the stated percentages by weight of the individual components a) to c) summing to 100%.
摘要翻译：不溶性的仅有微膨胀的爆米花状聚合物，其含有50-99重量％的苯乙烯和/或至少一种单不饱和苯乙烯衍生物，b）0.1-40重量％的至少一种N-乙烯基内酰胺或N-乙烯基胺，和c） 0.1至10重量％的至少一种双官能交联组分，所述各组分a）至c）的所述重量百分数相加至100％。

4. 发明授权

US06331294B1 Use of copolymers of monoethylenically unsaturated carboxylic acids as solubilizers 有权
标题翻译：使用单烯属不饱和羧酸的共聚物作为增溶剂
公开(公告)号：US06331294B1
公开(公告)日：2001-12-18
申请号：US09268720
申请日：1999-03-17
申请人： Helmut Meffert , Axel Sanner , Gunther Berndl , Folker Ruchatz , Karl Kolter , Kurt Heinz Bauer
发明人： Helmut Meffert , Axel Sanner , Gunther Berndl , Folker Ruchatz , Karl Kolter , Kurt Heinz Bauer
IPC分类号： A61K3174
CPC分类号： A61K8/8158 , A61K8/8152 , A61K9/0014 , A61K9/0019 , A61K9/1075 , A61K9/2027 , A61K9/4866 , A61K47/32 , A61Q13/00 , A61Q17/04 , C08F220/04
摘要： The invention relates to the use of copolymers comprising a) 82 to 99.9 mol % of at least one monoethylenically unsaturated C3-C8-carboxylic acid; b) 0.1 to 18 mol % of at least one monomer selected from the group b1) N—C8-C30-alkyl-substituted amides of monoethylenically unsaturated C3-C8-carboxylic acids, b2) N,N—C8-C30-dialkyl-substituted amides of monoethylenically unsaturated C3-C8-carboxylic acids, b3) C8-C30-alkyl esters of monoethylenically unsaturated C3-C8-carboxylic acids; c) 0 to 17.9 mol % of at least one monomer selected from the group of c1) vinyl esters of aliphatic C8-C30-carboxylic acids, c2) C8-C30-alkylvinyl ethers, mol % data for the individual components adding up to 100%, as solubilizer.
摘要翻译：本发明涉及包含a）82-99.9摩尔％的至少一种单烯属不饱和C 3 -C 8 - 羧酸的共聚物的用途; b）0.1至18摩尔％的至少一种选自b 1）N-C 8 -C 30 烷基取代的单烯属不饱和C3-C8-羧酸的酰胺，b2）单烯属不饱和C3-C8-羧酸的N，N-C8-C30-二烷基取代的酰胺，b3）单烯属不饱和的C 3 -C 30 - 烷基酯 C 3 -C 8 - 羧酸; c）0至17.9mol％的至少一种选自以下的单体：c1）脂肪族C 8 -C 30 - 羧酸的乙烯基酯，c 2）C 8 -C 30烷基乙烯基醚，mol％个别成分加起来可达100％，作为增溶剂。

5. 发明授权

US06329334B1 Use of crosslinked polyvinylpyrrolidone to increase the rate of disintegration of compact particular detergents and cleaners 有权
标题翻译：使用交联聚乙烯吡咯烷酮来增加紧凑型特定洗涤剂和清洁剂的崩解速率
公开(公告)号：US06329334B1
公开(公告)日：2001-12-11
申请号：US09525062
申请日：2000-03-14
申请人： Werner Bertleff , Folker Ruchatz , Richard Baur , Robert Heinz , Peter Palm
发明人： Werner Bertleff , Folker Ruchatz , Richard Baur , Robert Heinz , Peter Palm
IPC分类号： C11D722
CPC分类号： C11D17/0073 , C11D3/3776 , C11D17/06
摘要： The invention relates to the use of crosslinked polyvinylpyrrolidone as an additive to compact, particulate detergents and cleansers for the purpose of increasing the rate of disintegration thereof when brought into contact with water, to the particles of crosslinked polyvinylpyrrolidone having a particle size of from 50 to 400 &mgr;m, to a process for the preparation of the compact, particulate detergents and cleansers, and also to the compact, particulate detergents and cleansers themselves.
摘要翻译：本发明涉及交联聚乙烯吡咯烷酮作为添加剂的用途，用于压制颗粒洗涤剂和清洁剂，目的是在与水接触时将其崩解速率提高至粒径为50至 400微米，用于制备紧凑型颗粒洗涤剂和清洁剂的方法，以及致密的颗粒洗涤剂和清洁剂本身。

6. 发明授权

US07906144B1 Solubilizing aids in powder form for solid pharmaceutical presentation forms 有权
标题翻译：固体药物呈现形式的粉末形式的增溶助剂
公开(公告)号：US07906144B1
公开(公告)日：2011-03-15
申请号：US09937313
申请日：2000-10-05
申请人： Gunther Berndl , Jörg Breitenbach , Folker Ruchatz , Axel Sanner , Heinrich Sack
发明人： Gunther Berndl , Jörg Breitenbach , Folker Ruchatz , Axel Sanner , Heinrich Sack
IPC分类号： A61K9/14 , A61K9/50
CPC分类号： A61K9/2013 , A61K9/2027
摘要： The invention relates to excipients in powder form for use in solid pharmaceutical presentations, comprising a pharmaceutically acceptable polymer and a liquid or semisolid solubilizing surface-active substance.
摘要翻译：本发明涉及粉末形式的用于固体药物表现的赋形剂，其包含药学上可接受的聚合物和液体或半固体增溶表面活性物质。

7. 发明授权

US06436440B1 Use of N-vinyllactam-or-N-vinylamine-containing copolymers as matrix for producing solid pharmaceutical and cosmetic presentations 有权
标题翻译：使用N-乙烯基内酰胺或N-乙烯胺的共聚物作为制备固体药物和化妆品的基质
公开(公告)号：US06436440B1
公开(公告)日：2002-08-20
申请号：US09283195
申请日：1999-04-01
申请人： Helmut Meffert , Folker Ruchatz
发明人： Helmut Meffert , Folker Ruchatz
IPC分类号： A61K914
CPC分类号： A61Q19/00 , A61K8/817 , A61K9/2027 , C08F226/06
摘要： The use of copolymers comprising a) 50 to 99% by weight of at least one N-vinyllactam or N-vinylamine selected from the group consisting of N-vinylpyrrolidone, N-vinylpiperidone, N-vinylcaprolactam, N-vinylimidazole and methylated N-vinylimidazole or N-vinylformamide and b) 1 to 50% by weight of at least one monomer selected from the group of b1) C14-C30-alkyl esters of monoethylenically unsaturated C3-C8-carboxylic acids; b2) N—C8-C30-alkyl-substituted amides of monoethylenically unsaturated C3-C8-carboxylic acids; b3) N,N—C8-C30-dialkyl-substituted amides of monoethylenically unsaturated C3-C8-carboxylic acids; b4) vinyl esters of aliphatic C8-C30-carboxylic acids; b5) C8-C30-alkyl vinyl ethers as matrix for producing solid pharmaceutical and cosmetic presentations.
摘要翻译：包含a）50至99重量％的至少一种N-乙烯基内酰胺或N-乙烯胺的共聚物，其选自N-乙烯基吡咯烷酮，N-乙烯基哌啶酮，N-乙烯基己内酰胺，N-乙烯基咪唑和甲基化N-乙烯基咪唑，或的1-乙烯基甲酰胺和b）1至50重量％的至少一种选自b1）单烯属不饱和C 3 -C 8 - 羧酸的C 14 -C 30烷基酯的单体; b2）N-C 8 -C 30烷基取代的酰胺的单烯属不饱和C3-C8-羧酸; b3）单烯键式不饱和C3-C8-羧酸的N，N-C8-C30-二烷基取代的酰胺; b4）脂族C 8 -C 30 - 羧酸的乙烯基酯; b5）C8 用于制备固体药物和化妆品的-C30-烷基乙烯基醚基质。

8. 发明授权

US06271307B1 Use of polyalkylkene oxide-containing graft copolymers as solubilizers 有权
标题翻译：使用含烷基氧化烯的接枝共聚物作为增溶剂
公开(公告)号：US06271307B1
公开(公告)日：2001-08-07
申请号：US09283194
申请日：1999-04-01
申请人： Jürgen Huff , Helmut Meffert , Folker Ruchatz
发明人： Jürgen Huff , Helmut Meffert , Folker Ruchatz
IPC分类号： C08F29106
CPC分类号： A61Q13/00 , A61K8/91 , A61K9/0019 , A61K9/146 , A61K9/2031 , A61K9/4866 , A61K47/10 , A61K47/32 , A61Q17/04 , B01F17/0028 , B01F17/005
摘要： The use of graft copolymers obtainable by grafting a) polyalkylene oxides with b) at least one monomer selected from the group of b1) C1-C30-alkyl esters of monoethylenically unsaturated C3-C8-carboxylic acids; b2) vinyl esters of aliphatic C1-C30-carboxylic acids; b3) C1-C30-alkyl vinyl ethers; b4) N—C1-C12-alkyl-substituted amides of monoethylenically unsaturated C3-C8-carboxylic acids; b5) N,N—C1-C12-dialkyl-substituted amides of monoethylenically unsaturated C3-C8-carboxylic acids as solubilizer.
摘要翻译：使用可通过接枝方法得到的接枝共聚物）b）至少一种选自b1）单烯属不饱和C 3 -C 8羧酸的C 1 -C 30烷基酯的单体; b2）脂族C 1 -C 30羧酸的乙烯基酯酸; b3）C1-C30烷基乙烯基醚; b4）单烯属不饱和C 3 -C 8 - 羧酸的N-C 1 -C 12烷基取代的酰胺; b5）单烯属的N，N-C 1 -C 12 - 二烷基取代的酰胺不饱和C3-C8-羧酸作为增溶剂。

9. 发明授权

US06075107A Use of copolymers of N-vinylprrolidone in preparations of water-insoluble substances 失效
标题翻译： N-乙烯基吡咯烷酮共聚物在水不溶物质制剂中的应用
公开(公告)号：US06075107A
公开(公告)日：2000-06-13
申请号：US73856
申请日：1998-05-07
申请人： Stephan Kothrade , Helmut Meffert , Gunther Berndl , Axel Sanner , Stefan Stein , Volker Schehlmann , Folker Ruchatz
发明人： Stephan Kothrade , Helmut Meffert , Gunther Berndl , Axel Sanner , Stefan Stein , Volker Schehlmann , Folker Ruchatz
IPC分类号： A61K8/72 , A61K8/00 , A61K8/81 , A61K47/32 , A61Q19/00 , B01F17/32 , B01F17/52 , C08F226/10
CPC分类号： A61K47/32 , Y10S526/911
摘要： The use of copolymers ofA) 60-99 mol % of N-vinylpyrrolidone, andB) 1-40 mol % of a monomer selected from the group ofb1) C.sub.8 -C.sub.30 -alkyl esters of monoethylenically unsaturated C.sub.3 -C.sub.8 -carboxylic acids,b2) N-alkyl- or N,N-dialkyl-substituted amides of acrylic acid or of methacrylic acid with C.sub.8 -C.sub.18 -alkyl radicals, orb3) vinyl esters of aliphatic C.sub.8 -C.sub.30 -carboxylic acids, or mixtures of these monomers,as surface-active substances in preparations of water-insoluble substances.
摘要翻译：使用A）60-99摩尔％的N-乙烯基吡咯烷酮和B）1-40摩尔％的选自b1）C8-C30-单烯属不饱和C3-C8-羧酸烷基酯的单体的共聚物，b2）丙烯酸或甲基丙烯酸与C8-C18-烷基的N-烷基 - 或N，N-二烷基取代的酰胺，或b3-脂肪族C 8 -C 30 - 羧酸的乙烯基酯，或这些单体的混合物作为水不溶性物质制剂中的表面活性物质。

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