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    • 2. 发明授权
    • Fluorescence station for biological sample testing machine
    • 生物样品检测机荧光站
    • US5925884A
    • 1999-07-20
    • US799480
    • 1997-02-12
    • Ron RobinsonDavid B. ShineCraig DragerRichard James RyallErik William Anthon
    • Ron RobinsonDavid B. ShineCraig DragerRichard James RyallErik William Anthon
    • G01N21/27G01N21/64G01N35/00
    • G01N21/6452G01N21/276G01N21/6428G01N35/00029G01N2035/00049G01N2035/00099Y10T436/11Y10T436/113332Y10T436/114165
    • A sample card transport station moves a test sample card from an incubation station for the card to a transmittance and fluorescence optical station in a sample testing machine. The sample card transport station has a drive belt and an associated stepper motor. The belt supports the card from one side of the card. A ledge having a card slot is disposed above the belt. The card is snugly received within the card slot, and supported from below by the drive belt and rollers for the belt. When the motor turns the belt, the belt grips the card and slide the card along the slot to the optical stations, without any slippage between the belt and the card. This construction provides for precise control over the movement of the card.The fluorescence station has a linear flash lamp that illuminates a column of the wells of the cards simultaneously. A reference detector and dichromatic beam splitter design is used to insure that the fluorescence measurements are independent of lamp output changes over time. A solid reference is mounted to an optical shuttle and moved into the optical path to calibrate the fluorescence photodiode detectors.
    • 样本卡运送站将测试样本卡从卡的孵化站移动到样品测试机中的透射率和荧光光学站。 样品卡传送站具有传动带和相关的步进电机。 皮带从卡的一侧支持卡。 具有卡槽的凸缘设置在带上方。 卡片紧贴在卡槽内,并由传动带和传送带的滚筒从下方支撑。 当电机转动皮带时,皮带夹住卡,将卡沿插槽滑动到光学位置,皮带和卡之间不会发生任何滑动。 这种结构提供了对卡的移动的精确控制。 荧光站具有线性闪光灯,同时照亮卡的孔的列。 使用参考检测器和二色分束器设计来确保荧光测量与时间上的灯输出变化无关。 将固体参考安装到光梭上并移动到光路中以校准荧光光电二极管检测器。