专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20130094125A1 Electronic Meter Register And Method Having A Bottom Formed By Sealing Material 有权
标题翻译：电子计量表和通过密封材料形成底部的方法
公开(公告)号：US20130094125A1
公开(公告)日：2013-04-18
申请号：US13273426
申请日：2011-10-14
申请人： Dennis W. Schwartz , Eric Metzger , John A. Olson , Ronald D. Benson , Eric Tabaska
发明人： Dennis W. Schwartz , Eric Metzger , John A. Olson , Ronald D. Benson , Eric Tabaska
IPC分类号： H05K5/00 , H05K13/00
CPC分类号： G01D4/002 , G01F15/068 , G01F15/14 , H05K5/062 , Y02B90/241 , Y04S20/32 , Y10T29/49002
摘要： A sealed electronic meter register with no moving parts and no bottom wall or bottom cover includes a casing of plastic with an open bottom. A viewing window is snap fitted into a top wall of the casing. A gasket is placed on top of an electronic numerical display and under the viewing window. The display is placed on top of a frame that is positioned face down into the casing. An electronic circuit board with the processing circuitry of the device is attached to the bottom of the frame. A polyurethane compound sealing material is deposited though a hole in the circuit board and onto the backside of the display. An epoxy-resin sealant is then deposited from the bottom of the housing to seal over everything in the housing to protect the components and provide an exposed bottom surface for the assembly.
摘要翻译：密封的电子计量表没有移动部件，没有底壁或底盖包括具有开口底部的塑料外壳。观察窗被卡扣到套管的顶壁上。垫片放置在电子数字显示屏的顶部，并在观察窗口下方。显示器被放置在面向下定位到壳体中的框架的顶部上。具有该设备的处理电路的电子电路板被附接到该框架的底部。聚氨酯复合材料密封材料通过电路板上的孔和显示器的背面沉积。然后从壳体的底部沉积环氧树脂密封剂以密封壳体中的所有部件，以保护部件并提供用于组件的暴露的底部表面。

2. 发明申请

US20120096568A1 TRANSGENIC LSD1 ANIMAL MODEL FOR CANCER 审中-公开
标题翻译： TRANSGENIC LSD1动物模型
公开(公告)号：US20120096568A1
公开(公告)日：2012-04-19
申请号：US13376212
申请日：2010-04-28
申请人： Roland Schuele , Thomas Guenther , Eric Metzger
发明人： Roland Schuele , Thomas Guenther , Eric Metzger
IPC分类号： A61K49/00 , C12N15/85 , A01K67/027
CPC分类号： C12N15/8509 , A01K2217/072 , A01K2227/105 , A01K2267/0331
摘要： The present invention relates to a non-human transgenic animal whose genome comprises a stably integrated transgenic nucleotide sequence encoding Lysine-specific Demethylase 1 (LSD1) operably linked to a promoter. The invention further concerns methods for generating the non-human animal and its use as a cancer model.
摘要翻译：本发明涉及非人转基因动物，其基因组包含可操作地连接于启动子的编码赖氨酸特异性脱甲基酶1（LSD1）的稳定整合的转基因核苷酸序列。本发明还涉及产生非人类动物的方法及其作为癌症模型的用途。

3. 发明申请

US20080139665A1 Androgen Receptor-Dependent Gene Expression Control 有权
标题翻译：雄激素受体依赖基因表达控制
公开(公告)号：US20080139665A1
公开(公告)日：2008-06-12
申请号：US11884568
申请日：2006-02-16
申请人： Roland Schuele , Eric Metzger
发明人： Roland Schuele , Eric Metzger
IPC分类号： A61K31/137 , C12Q1/48
CPC分类号： A61K31/138 , A61K31/137 , A61K31/7088 , C12Q1/26 , C12Q1/48 , G01N33/743 , G01N2333/91011 , G01N2500/04
摘要： The invention relates to the use of at least one amine oxidase inhibitor for modulating the activity of the lysine-specific demethylase (LSD1) in a mammal and to pharmaceutical compositions for controlling the androgen receptor-dependent gene expression, comprising an effective dose of at least one amine oxidase inhibitor suitable for modulating the activity of the lysine-specific demethylase (LSD1) in a mammal. The invention also relates to assay systems allowing to test LSD1 inhibitors for their ability to inhibit LSD1 function.
摘要翻译：本发明涉及至少一种胺氧化酶抑制剂用于调节哺乳动物中赖氨酸特异性脱甲基酶（LSD1）的活性和用于控制雄激素受体依赖性基因表达的药物组合物的用途，其包含至少有效剂量一种适于调节哺乳动物赖氨酸特异性脱甲基酶（LSD1）活性的胺氧化酶抑制剂。本发明还涉及允许测试LSD1抑制剂抑制LSD1功能的能力的测定系统。

4. 发明申请

US20070196882A1 Assay system for specific inhibitors of protein kinase c-related kinases 失效
标题翻译：蛋白激酶c相关激酶特异性抑制剂的测定系统
公开(公告)号：US20070196882A1
公开(公告)日：2007-08-23
申请号：US10592313
申请日：2005-03-10
申请人： Roland Schuele , Eric Metzger
发明人： Roland Schuele , Eric Metzger
IPC分类号： C12Q1/48 , A61K31/56
CPC分类号： G01N33/5011 , G01N33/566 , G01N2333/9121
摘要： The present invention relates to an assay system for specific inhibitors of protein kinase C-related kinases (PRKs) relating to one or more of the reactions wherein said protein kinase C-related kinases are involved under physiological conditions. The invention also relates to a process for identifying specific inhibitors for protein kinase C-related kinases.
摘要翻译：本发明涉及与一种或多种反应相关的蛋白激酶C-相关激酶（PRK）的特异性抑制剂的测定系统，其中所述蛋白激酶C-相关激酶参与生理条件。本发明还涉及用于鉴定蛋白激酶C相关激酶的特异性抑制剂的方法。

5. 发明授权

US07143645B2 Meter housing assembly and method of assembly 有权
标题翻译：仪表外壳总成及组装方法
公开(公告)号：US07143645B2
公开(公告)日：2006-12-05
申请号：US10831990
申请日：2004-04-26
申请人： Ronald D. Benson , Eric Metzger , Lee Karsten , H. Paul Walding, Jr.
发明人： Ronald D. Benson , Eric Metzger , Lee Karsten , H. Paul Walding, Jr.
IPC分类号： G01F3/32 , G01F15/14
CPC分类号： G01F3/12 , G01F15/18
摘要： A water meter housing assembly (10) comprises a cylindrical, plastic housing body (11), a non-cast housing bottom (13) of hydroformable or stamped brass, a single-piece strainer and sealing member (40) that is disposed in the housing bottom (13) and portions of non-cast hydroformable or stamped brass tubing (15) with spud ends (16, 17) for connection in a water supply line. The brass consists essentially of lead-free material. The assembly (10) is designed to provide a lower cost alternative to foundry cast meter housings. The assembly (10) also provides advantages in a method of vertical assembly that saves manufacturing cost.
摘要翻译：水表壳体组件（10）包括圆柱形塑料壳体（11），可压缩成形或冲压黄铜的非铸造壳体底部（13），单件过滤器和密封构件（40），其设置在壳体底部（13）和具有用于连接在供水管线中的端头（16,17）的非铸造可压缩成形或冲压的黄铜管（15）的部分。黄铜基本上由无铅材料组成。组件（10）被设计成为铸造铸件表壳提供较低成本的替代方案。组件（10）还提供垂直组装方法的优点，从而节省制造成本。

6. 发明申请

US20100285026A1 PHOSPHORYLATION OF HISTONE H3 AT THREONINE 11 - A NOVEL EPIGENETIC MARK FOR TRANSCRIPTIONAL REGULATION 失效
标题翻译： HISTONE H3在THREONINE 11的磷酸化 - 一个新的重要标志进行转录调节
公开(公告)号：US20100285026A1
公开(公告)日：2010-11-11
申请号：US12669294
申请日：2008-05-27
申请人： Roland Schuele , Eric Metzger
发明人： Roland Schuele , Eric Metzger
IPC分类号： A61K39/395 , C12N5/02 , C12Q1/48 , A61P35/00
CPC分类号： C07K14/47 , A61K38/00 , C07K14/721 , C07K16/40 , C12N9/1205 , C12N15/1137 , C12N2310/111 , C12N2310/14 , C12Q1/485 , C12Y207/11013 , G01N33/57434 , G01N2333/723 , G01N2333/91215 , G01N2500/00
摘要： The present invention relates to a process for controlling at least one androgen receptor- (AR-) regulated mechanism in mammalian cells under histone-phosphorylating conditions, said process comprising allowing at least one inhibitor with specificity for at least one protein kinase C-related kinase (PRK) to act on said at least one PRK1 thereby modulating, preferably down-regulating, the activity of said at least one PRK and optionally blocking said at least one androgen receptor-regulated mechanism in said mammalian cells.
摘要翻译：本发明涉及在组蛋白 - 磷酸化条件下控制哺乳动物细胞中至少一种雄激素受体（AR））调节机制的方法，所述方法包括允许至少一种具有至少一种蛋白激酶C相关激酶特异性的抑制剂（PRK）作用于所述至少一种PRK1，从而调节，优选下调所述至少一种PRK的活性，并任选地阻断所述哺乳动物细胞中的所述至少一种雄激素受体调节机制。

7. 发明申请

US20070186644A1 Meter with integral register having no visual display of consumption 有权
标题翻译：具有积分寄存器的仪表没有消费的可视显示
公开(公告)号：US20070186644A1
公开(公告)日：2007-08-16
申请号：US11353773
申请日：2006-02-14
申请人： Mark Lazar , Ronald Benson , Eric Metzger , Kelly Laughlin-Parker , Joseph Stauber
发明人： Mark Lazar , Ronald Benson , Eric Metzger , Kelly Laughlin-Parker , Joseph Stauber
IPC分类号： G01F15/14
CPC分类号： G01F15/063 , G01F3/12
摘要： A combined utility meter and meter register assembly (10) is disclosed in which a housing (11, 13, 31) for both a utility metering element and a meter register has no visual readout or display of metering data. Metering data is signaled through a data port (33) or an antenna (36) to external equipment. The meter register is provided by electronic circuitry (29a, 29b) that is placed in an upper cavity (27) in the housing part (13) that is then closed by a cover (31) or a body of sealing material. A label (32) can be placed over the closure informational purposes. An additional embodiment of the housing is also disclosed.
摘要翻译：公开了一种组合的效用仪表和仪表寄存器组件（10），其中用于公用计量元件和仪表寄存器的壳体（11,13,31）没有视觉读取或显示计量数据。计量数据通过数据端口（33）或天线（36）发送到外部设备。仪表寄存器由放置在壳体部分（13）中的上腔（27）中的电子电路（29a，29b）提供，然后由盖（31）或密封材料体封闭。标签（32）可以放置在封闭信息的目的上。还公开了外壳的另外的实施例。

8. 发明授权

US08929096B2 Kit for installation of water meter reading equipment in three configurations 有权
标题翻译：水表读取设备安装在三种配置中的套件
公开(公告)号：US08929096B2
公开(公告)日：2015-01-06
申请号：US13467702
申请日：2012-05-09
申请人： Eric Metzger
发明人： Eric Metzger
IPC分类号： H02B1/20
CPC分类号： G01D4/002 , G01D4/008 , Y02B90/241 , Y02B90/247 , Y04S20/32 , Y04S20/50
摘要： A kit is disclosed for installing a radio frequency transmitter assembly (30) in position for radio transmission and reception when connected to a water meter register (26, 40) that is situated below ground level, the kit comprising: a base member (22) for extending substantially horizontally from the meter register (26, 40); a transmitter assembly (30) having a transmitter body (32) for attachment to the base member (22) with the transmitter body in an upright position; an electrical cable (17) connected at one end to the meter register (26, 40) and connected at an opposite end to the transmitter assembly (30). The kit provides a product that can be installed in any one of three different configurations.
摘要翻译：公开了一种用于在连接到位于地平面以下的水表寄存器（26,40）之前将无线电频率发射器组件（30）安装在适合无线电发射和接收的位置的套件，所述套件包括：基座构件（22）用于从所述仪表寄存器（26,40）基本水平地延伸; 发射器组件（30），其具有用于附接到所述基座构件（22）的发射器主体（32），所述发射器主体处于直立位置; 电缆（17），其一端连接到仪表寄存器（26,40），并在相对端连接到发射机组件（30）。该套件提供可以安装在三种不同配置中的任何一种的产品。

9. 发明申请

US20130301190A1 Kit For Installation Of Water Meter Reading Equipment In Three Configurations 有权
标题翻译：三台配置中水表读数设备安装套件
公开(公告)号：US20130301190A1
公开(公告)日：2013-11-14
申请号：US13467702
申请日：2012-05-09
申请人： Eric Metzger
发明人： Eric Metzger
IPC分类号： H05K7/00
CPC分类号： G01D4/002 , G01D4/008 , Y02B90/241 , Y02B90/247 , Y04S20/32 , Y04S20/50
摘要： A kit is disclosed for installing a radio frequency transmitter assembly (30) in position for radio transmission and reception when connected to a water meter register (26, 40) that is situated below ground level, the kit comprising: a base member (22) for extending substantially horizontally from the meter register (26, 40); a transmitter assembly (30) having a transmitter body (32) for attachment to the base member (22) with the transmitter body in an upright position; an electrical cable (17) connected at one end to the meter register (26, 40) and connected at an opposite end to the transmitter assembly (30). The kit provides a product that can be installed in any one of three different configurations.
摘要翻译：公开了一种用于在连接到位于地平面以下的水表寄存器（26,40）之前将无线电频率发射器组件（30）安装在适合无线电发射和接收的位置的套件，所述套件包括：基座构件（22）用于从所述仪表寄存器（26,40）基本水平地延伸; 发射器组件（30），其具有用于附接到所述基座构件（22）的发射器主体（32），所述发射器主体处于直立位置; 电缆（17），其一端连接到仪表寄存器（26,40），并在相对端连接到发射机组件（30）。该套件提供可以安装在三种不同配置中的任何一种的产品。

10. 发明授权

US08482908B2 Electronic meter register and method having a bottom formed by sealing material 有权
标题翻译：具有通过密封材料形成的底部的电子计量表和方法
公开(公告)号：US08482908B2
公开(公告)日：2013-07-09
申请号：US13273426
申请日：2011-10-14
申请人： Dennis W. Schwartz , Eric Metzger , John A. Olson , Ronald D. Benson , Eric Tabaska
发明人： Dennis W. Schwartz , Eric Metzger , John A. Olson , Ronald D. Benson , Eric Tabaska
IPC分类号： H05K7/00 , G01R35/04
CPC分类号： G01D4/002 , G01F15/068 , G01F15/14 , H05K5/062 , Y02B90/241 , Y04S20/32 , Y10T29/49002
摘要： A sealed electronic meter register with no moving parts and no bottom wall or bottom cover includes a casing of plastic with an open bottom. A viewing window is snap fitted into a top wall of the casing. A gasket is placed on top of an electronic numerical display and under the viewing window. The display is placed on top of a frame that is positioned face down into the casing. An electronic circuit board with the processing circuitry of the device is attached to the bottom of the frame. A polyurethane compound sealing material is deposited though a hole in the circuit board and onto the backside of the display. An epoxy-resin sealant is then deposited from the bottom of the housing to seal over everything in the housing to protect the components and provide an exposed bottom surface for the assembly.
摘要翻译：密封的电子计量表没有移动部件，没有底壁或底盖包括一个开放的底部的塑料外壳。观察窗被卡扣到套管的顶壁上。垫片放置在电子数字显示屏的顶部，并在观察窗口下方。显示器被放置在面向下定位到壳体中的框架的顶部上。具有该设备的处理电路的电子电路板被附接到该框架的底部。聚氨酯复合材料密封材料通过电路板上的孔和显示器的背面沉积。然后从壳体的底部沉积环氧树脂密封剂以密封壳体中的所有部件，以保护部件并提供用于组件的暴露的底部表面。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式