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1. 发明授权

US08387826B2 Beverage dispensing apparatus 有权
标题翻译：饮料分配装置
公开(公告)号：US08387826B2
公开(公告)日：2013-03-05
申请号：US12309406
申请日：2007-07-13
申请人： Syunji Tsubouchi , Eiji Hara , Fumitaka Saitou
发明人： Syunji Tsubouchi , Eiji Hara , Fumitaka Saitou
IPC分类号： B67D7/06
CPC分类号： B67D1/0406 , B67D1/0864 , B67D1/0888 , B67D1/1211 , B67D1/1222 , B67D1/1252 , B67D1/1272 , G01F1/00 , G01F1/6888 , G01F15/046 , G01F22/00
摘要： A beverage dispenser has gauges to measure the temperature of the beverage, in at least one embodiment beer, stored in a closed beverage container. The beverage is pressurized and a pressure gauge in the gas supply conduit line measures the pressure of the gas in the beverage container. A pressure regulator in the gas supply conduit line assists in ensuring that the pressure is consistent. The valve is closed during dispensation and the temperature and the gas pressure are measured immediately afterwards. By calculating the temperature change of the beverage and the pressure drop in the container, the amount of beverage can be calculated accurately. This in turn can be utilized to reliably calculate how beverage is left in the container and this information is then presented on a display, in at least one embodiment, as a series of indicator bars.
摘要翻译：饮料分配器具有用于测量饮料温度的量具，在至少一个实施方案中，储存在封闭的饮料容器中的啤酒。饮料被加压，并且气体供应管线中的压力表测量饮料容器中的气体的压力。气体供应管道管道中的压力调节器有助于确保压力一致。阀门在分配期间关闭，然后立即测量温度和气体压力。通过计算饮料的温度变化和容器中的压降，可以精确地计算饮料量。这又可以用于可靠地计算饮料在容器中的剩余情况，然后在至少一个实施例中将该信息呈现在显示器上作为一系列指示条。

2. 发明申请

US20090240052A1 NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF 失效
标题翻译：新戊酸衍生物或其盐
公开(公告)号：US20090240052A1
公开(公告)日：2009-09-24
申请号：US11721007
申请日：2005-12-06
申请人： Junichi Yokotani , Yoichi Taniguchi , Eiji Hara , Hitoshi Akitsu , Yukie Tada
发明人： Junichi Yokotani , Yoichi Taniguchi , Eiji Hara , Hitoshi Akitsu , Yukie Tada
IPC分类号： C07D413/02 , C07D277/20 , C07C229/52 , C07D213/55 , C07D209/04 , C07D241/36
CPC分类号： C07C233/87 , C07C233/51 , C07C233/63 , C07C233/81 , C07C235/16 , C07C235/38 , C07C237/40 , C07C311/13 , C07C311/21 , C07C317/48 , C07C323/58 , C07C323/63 , C07C2601/02 , C07C2601/14 , C07D207/327 , C07D207/416 , C07D209/08 , C07D209/34 , C07D211/14 , C07D211/32 , C07D211/70 , C07D213/55 , C07D213/81 , C07D213/82 , C07D217/04 , C07D231/12 , C07D231/14 , C07D235/06 , C07D239/28 , C07D241/42 , C07D249/18 , C07D257/04 , C07D261/18 , C07D277/30 , C07D277/68 , C07D285/14 , C07D295/155 , C07D307/54 , C07D307/68 , C07D307/79 , C07D307/81 , C07D307/85 , C07D317/60 , C07D317/68 , C07D319/18 , C07D333/24 , C07D333/38 , C07D333/54 , C07D333/60 , C07D333/68 , C07D333/70 , C07D401/04 , C07D405/14 , C07D407/12 , C07D409/04 , Y02P20/55
摘要： An anthranilic acid derivative represented by the general formula (X) [wherein R1 represents hydrogen or a carboxy-protecting group; R2 represents optionally substituted phenyl, a heterocyclic group, etc.; R3 represents optionally substituted phenyl, a monocyclic heterocyclic group, etc.; X1 represents carbonyl, etc.; X2 represents optionally substituted alkylene group, a bond, etc.; X3 represents oxygen, a bond, etc.; and X4 represents a group represented by the general formula -X5-X6- or -X6-X5- (wherein X5 means oxygen, a bond, etc.; and X6 means optionally substituted alkylene, a bond, etc.)] or a salt of the derivative. The derivative or salt has the inhibitory activity of MMP-13 production and is hence useful as a therapeutic agent for articular rheumatism, osteoarthritis, cancer, etc.
摘要翻译：由通式（X）表示的邻氨基苯甲酸衍生物[其中R1表示氢或羧基保护基; R 2表示任选取代的苯基，杂环基等; R3表示任选取代的苯基，单环杂环基等; X1代表羰基等; X2表示任选取代的亚烷基，键等; X3表示氧，键等; X4表示由通式-X5-X6-或-X6-X5-表示的基团（其中X5表示氧，键等; X6表示任选取代的亚烷基，键等）]或盐的衍生物。衍生物或盐具有MMP-13产生的抑制活性，因此可用作关节风湿病，骨关节炎，癌症等的治疗剂。

3. 发明申请

US20090194564A1 BEVERAGE DISPENSING APPARATUS 有权
标题翻译：饮料配料设备
公开(公告)号：US20090194564A1
公开(公告)日：2009-08-06
申请号：US12309406
申请日：2007-07-13
申请人： Syunji Tsubouchi , Eiji Hara , Fumitaka Saitou
发明人： Syunji Tsubouchi , Eiji Hara , Fumitaka Saitou
IPC分类号： B67D5/06 , B67D5/08
CPC分类号： B67D1/0406 , B67D1/0864 , B67D1/0888 , B67D1/1211 , B67D1/1222 , B67D1/1252 , B67D1/1272 , G01F1/00 , G01F1/6888 , G01F15/046 , G01F22/00
摘要： A beverage dispenser includes beverage temperature measurement means for measuring a temperature of beverage stored in a closed beverage container; pressure measurement means disposed in a gas supply conduit supplying gas into the beverage container from a source of pressurized gas for measuring a gas pressure in the beverage container; a pressure regulator valve disposed in the gas supply conduit for regulating a pressure of gas supplied to the beverage container; discharge means for discharging an amount of beverage supplied thereto from a beverage supply conduit connected to the beverage container; wherein the pressure regulator valve is opened and closed in such a manner that the gas pressure in the container becomes a proper pressure calculated in accordance with a temperature of the beverage measured by the temperature measurement means, wherein the beverage dispenser further comprises gas flow measurement means disposed in the gas supply conduit at a downstream of the pressure regulator valve for measuring a flow amount of gas supplied to the beverage container calculation means for calculating an amount of beverage remained in the container or discharged from the container on a basis of the flow amount of gas measured by the gas flow rate measurement means; and display means for indicating the calculated amount of beverage remained in the container or discharged from the container.
摘要翻译：饮料分配器包括用于测量储存在封闭饮料容器中的饮料的温度的饮料温度测量装置; 压力测量装置，设置在从用于测量饮料容器中的气体压力的加压气体源将气体供应到饮料容器中的气体供应管道中; 设置在气体供给管道中的压力调节阀，用于调节供应到饮料容器的气体的压力; 排出装置，用于从连接到饮料容器的饮料供应导管排放一定量的饮料; 其中所述压力调节阀以使得所述容器中的气体压力变为根据由所述温度测量装置测量的饮料的温度计算的适当压力的方式打开和关闭，其中所述饮料分配器还包括气体流量测量装置设置在压力调节阀的下游的气体供给管道中，用于测量供应到饮料容器的气体的流量计算装置，用于根据流量来计算残留在容器中或从容器排出的饮料量由气体流量测量装置测量的气体; 以及显示装置，用于指示剩余在容器中或从容器排出的饮料的计算量。

4. 发明授权

US5527897A Human ID genes 失效
标题翻译：人类基因
公开(公告)号：US5527897A
公开(公告)日：1996-06-18
申请号：US151391
申请日：1993-11-12
申请人： Kinichiro Oda , Susumu Nakada , Eiji Hara , Tomoko Yamaguchi , Takeshi Nakamura , Yumiko Oka , Toshihiko Kishimoto
发明人： Kinichiro Oda , Susumu Nakada , Eiji Hara , Tomoko Yamaguchi , Takeshi Nakamura , Yumiko Oka , Toshihiko Kishimoto
IPC分类号： A61K31/70 , A61K38/00 , C07H21/04 , C07K14/00 , C07K14/47 , C12N1/21 , C12N15/09 , C12N15/12 , C12Q1/68 , C12R1/19 , C12N15/00
CPC分类号： C07K14/4703 , A61K38/00
摘要： Disclosed herein are Human Id genes (Id-1H and Id-1H') and variants thereof. Origin, preparation process, biochemical functions and the like: two synthetic oligonucleotides separately having base sequences corresponding to regions of amino acid sequence, which are almost completely conserved by three mouse Id genes (Id-1, Id-2 and HLH462) are used as probes to screen clones having respective cDNAs complementary to the probes from a cDNA library of human TIG-1 fibroblasts in accordance with the hybridization method, thereby isolating human Id genes. The expression of the human Id genes specifically varies according to the state of cell proliferation, in particular, the acquisition of cell aging and permanently proliferating ability.Expression vectors with the human Id gene or variant thereof integrated therein, transformed cell strains with the expression vector introduced therein, diagnostic probes obtained by chemically synthesizing a partial sequence of the base sequence of the human Id gene, or a variation sequence thereof, and antisense oligonucleotides composed of a base sequences complementary to the partial sequence of the base sequence of the human Id gene, or the variation sequence thereof are also disclosed.
摘要翻译：本文公开了人Id基因（Id-1H和Id-1H'）及其变体。原产地，制备方法，生物化学功能等：分别具有对应于三个小鼠Id基因（Id-1，Id-2和HLH462）几乎完全保守的氨基酸序列区域的碱基序列的两个合成寡核苷酸被用作探针根据杂交方法筛选具有与人TIG-1成纤维细胞的cDNA文库互补的各cDNA的克隆，从而分离人Id基因。人Id基因的表达特异性地根据细胞增殖的状态而变化，特别是获得细胞衰老和永久增殖能力。其中整合了人Id基因或其变体的表达载体，其中引入了表达载体的转化细胞株，通过化学合成人Id基因的碱基序列的部分序列或其变异序列获得的诊断探针，以及反义还公开了由与人Id基因的碱基序列的部分序列互补的碱基序列或其变异序列组成的寡核苷酸。

5. 发明授权

US07999132B2 Anthranilic acid derivative or salt thereof 失效
标题翻译：邻氨基苯甲酸衍生物或其盐
公开(公告)号：US07999132B2
公开(公告)日：2011-08-16
申请号：US11721007
申请日：2005-12-06
申请人： Junichi Yokotani , Yoichi Taniguchi , Eiji Hara , Hitoshi Akitsu , Yukie Tada
发明人： Junichi Yokotani , Yoichi Taniguchi , Eiji Hara , Hitoshi Akitsu , Yukie Tada
IPC分类号： C07C233/55 , C07C233/63 , C07C233/81 , C07C235/24 , C07C311/13 , C07C311/21 , C07C317/50
CPC分类号： C07C233/87 , C07C233/51 , C07C233/63 , C07C233/81 , C07C235/16 , C07C235/38 , C07C237/40 , C07C311/13 , C07C311/21 , C07C317/48 , C07C323/58 , C07C323/63 , C07C2601/02 , C07C2601/14 , C07D207/327 , C07D207/416 , C07D209/08 , C07D209/34 , C07D211/14 , C07D211/32 , C07D211/70 , C07D213/55 , C07D213/81 , C07D213/82 , C07D217/04 , C07D231/12 , C07D231/14 , C07D235/06 , C07D239/28 , C07D241/42 , C07D249/18 , C07D257/04 , C07D261/18 , C07D277/30 , C07D277/68 , C07D285/14 , C07D295/155 , C07D307/54 , C07D307/68 , C07D307/79 , C07D307/81 , C07D307/85 , C07D317/60 , C07D317/68 , C07D319/18 , C07D333/24 , C07D333/38 , C07D333/54 , C07D333/60 , C07D333/68 , C07D333/70 , C07D401/04 , C07D405/14 , C07D407/12 , C07D409/04 , Y02P20/55
摘要： An anthranilic acid derivative represented by the general formula (X) [wherein R1 represents hydrogen or a carboxy-protecting group; R2 represents optionally substituted phenyl, a heterocyclic group, etc.; R3 represents optionally substituted phenyl, a monocyclic heterocyclic group, etc.; X1 represents carbonyl, etc.; X2 represents optionally substituted alkylene group, a bond, etc.; X3 represents oxygen, a bond, etc.; and X4 represents a group represented by the general formula —X5—X6— or —X6—X5— (wherein X5 means oxygen, a bond, etc.; and X6 means optionally substituted alkylene, a bond, etc.)] or a salt of the derivative. The derivative or salt has the inhibitory activity of MMP-13 production and is hence useful as a therapeutic agent for articular rheumatism, osteoarthritis, cancer, etc.
摘要翻译：由通式（X）表示的邻氨基苯甲酸衍生物[其中R1表示氢或羧基保护基; R 2表示任选取代的苯基，杂环基等; R3表示任选取代的苯基，单环杂环基等; X1代表羰基等; X2表示任选取代的亚烷基，键等; X3表示氧，键等; X4表示由通式-X5-X6-或-X6-X5-表示的基团（其中X5表示氧，键等; X6表示任选取代的亚烷基，键等）]或盐的衍生物。衍生物或盐具有MMP-13产生的抑制活性，因此可用作关节风湿病，骨关节炎，癌症等的治疗剂。

6. 发明申请

US20100108875A1 METHOD OF ANALYZING MINUTE QUANTITY OF CONTENT 有权
标题翻译：分析内容数量的方法
公开(公告)号：US20100108875A1
公开(公告)日：2010-05-06
申请号：US10576254
申请日：2004-10-14
申请人： Jiro Naka , Hiroshi Kurokawa , Junji Kobayashi , Satoru Toyama , Noriko Hirano , Eiji Hara
发明人： Jiro Naka , Hiroshi Kurokawa , Junji Kobayashi , Satoru Toyama , Noriko Hirano , Eiji Hara
IPC分类号： H01J49/26 , B01D59/44
CPC分类号： G01N1/4055 , G01N33/442 , G01N2001/4061 , G01N2030/009 , Y10T436/24
摘要： A sample preparation for analyzing a minute quantity of a content included in a material is performed by short-time extraction treatment without long-time extraction treatment, and the minute quantity of the content in the material is rapidly analyzed. The method of analyzing a minute quantity of a content includes mounting on a sample table a sample piece of a material to be analyzed; dropping onto the sample table the solvent for extracting the content from the sample piece, and injecting the solvent into a gap between the sample table and the sample piece; maintaining at room temperature the solvent injected into the gap between the sample table and the sample piece, and, with the solvent maintained in the gap between the sample table and the sample piece, extracting the content from the sample piece; and analyzing the content extracted from the sample piece.
摘要翻译：通过不进行长时间提取处理的短时间提取处理来进行用于分析材料中包含的微量的含量的样品制剂，并且快速分析材料中的微量的含量。分析微量内容的方法包括在样品台上安装待分析材料的样品片; 在样品台上滴加用于从样品中提取含量的溶剂，并将溶剂注入到样品台和样品片之间的间隙中; 在室温下保持注入到样品台和样品片之间的间隙中的溶剂，并且将溶剂保持在样品台和样品片之间的间隙中，从样品中提取含量; 并分析从样品片提取的内容。

7. 发明授权

US06977125B2 Closed type battery 有权
标题翻译：闭式电池
公开(公告)号：US06977125B2
公开(公告)日：2005-12-20
申请号：US10292435
申请日：2002-11-13
申请人： Tetsuhiro Oogaku , Eiji Hara
发明人： Tetsuhiro Oogaku , Eiji Hara
IPC分类号： H01M2/04 , H01M2/02 , H01M2/06 , H01M2/08 , H01M2/30 , H01M10/34
CPC分类号： H01M2/06 , H01M2/0217 , H01M2/30 , H01M10/0525 , H01M10/34
摘要： The present invention provides a closed type battery that is free from any sealing defects due to a sag of caulking with time, etc. The closed type battery is constructed of a monolithic electrode terminal that comprises an insulating member for covering the inner surface of a through-hole formed through a metal sheet for sealing up an opening of a battery can and both surfaces of the metal sheet around the through-hole, and an electrode-drawing sheet having a synthetic resin layer formed on one surface thereof, which sheet is located on the surface of the insulating member positioned on the outer surface of the battery while the synthetic resin layer comes in contact therewith, wherein the electrode-drawing sheet and the insulating member are integrated together by means of an electrode-leading pin passed through a through-hole in the electrode-drawing sheet.
摘要翻译：本发明提供了一种封闭式电池，其由于随时间而产生的堵缝而无任何密封缺陷。封闭式电池由单片电极端子构成，该单片电极端子包括用于覆盖通孔的内表面的绝缘构件通过用于密封电池壳的开口的金属板和围绕通孔的金属片的两个表面形成的孔，以及在其一个表面上形成有该片材的合成树脂层的电极拉伸片在合成树脂层与其接触的位于电池外表面的绝缘构件的表面上，其中电极拉伸片和绝缘构件通过电极引脚穿过通孔在电极图纸中。

8. 发明授权

US06702159B2 Pouring spout for sparkling beverages 有权
标题翻译：浇注出口用于起泡饮料
公开(公告)号：US06702159B2
公开(公告)日：2004-03-09
申请号：US10161468
申请日：2002-05-31
申请人： Sukehide Itou , Shigekazu Kondou , Fumitaka Saitou , Shunji Tsubouchi , Eiji Hara , Satoru Kobayashi , Kouji Sutou
发明人： Sukehide Itou , Shigekazu Kondou , Fumitaka Saitou , Shunji Tsubouchi , Eiji Hara , Satoru Kobayashi , Kouji Sutou
IPC分类号： B65D8300
CPC分类号： B67D1/1411 , B67D1/145
摘要： A first operation of a lever causes a valve rod to retract axially through a second valve element seated on a second valve seat against a first resilient part, while a first valve element to leave a first valve seat open to pour beer from a beer pouring nozzle through a beer supply channel. A second operation of the lever causes a slider to advance axially against a second resilient part to be spaced away from the valve rod forcing the first valve element to be seated on the first valve seat, while the second valve element to leave the second valve seat open to effect frothing of the beer from a liquid passage and pour the resulting froth through holes defined in a sleeve.
摘要翻译：杠杆的第一操作使得阀杆轴向地缩回通过位于第二阀座上的第二阀元件抵靠第一弹性部分，而第一阀元件离开第一阀座打开以从啤酒倾倒喷嘴倒入啤酒通过啤酒供应渠道。杠杆的第二操作导致滑块朝向第二弹性部件轴向前进，以与阀杆间隔开，迫使第一阀元件就位于第一阀座上，而第二阀元件离开第二阀座打开以实现来自液体通道的啤酒的起泡，并将所产生的泡沫倒入通过定义在套筒中的孔。

9. 发明申请

US20090105474A1 NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF 失效
标题翻译：新戊酸衍生物或其盐
公开(公告)号：US20090105474A1
公开(公告)日：2009-04-23
申请号：US11908879
申请日：2006-03-14
申请人： Junichi Yokotani , Yoichi Taniguchi , Eiji Hara , Hitoshi Akitsu , Hidehiko Tanaka , Shuzo Anzai
发明人： Junichi Yokotani , Yoichi Taniguchi , Eiji Hara , Hitoshi Akitsu , Hidehiko Tanaka , Shuzo Anzai
IPC分类号： C07C229/54 , C07D317/46 , C07D307/78 , C07D209/14 , C07D333/22 , C07D213/55 , C07D217/02 , C07D333/72 , C07D215/38 , C07C321/26 , C07D319/12 , C07D231/10 , C07D295/12 , C07D277/00 , C07D285/12 , C07D261/14
CPC分类号： C07D277/66 , C07C229/58 , C07C229/64 , C07C229/66 , C07C233/54 , C07C255/58 , C07C255/59 , C07C311/08 , C07C311/21 , C07C323/58 , C07C323/63 , C07D207/325 , C07D209/08 , C07D209/34 , C07D215/40 , C07D217/02 , C07D217/22 , C07D231/12 , C07D231/38 , C07D231/56 , C07D235/06 , C07D241/46 , C07D261/14 , C07D277/42 , C07D285/135 , C07D295/135 , C07D307/66 , C07D307/79 , C07D309/12 , C07D317/66 , C07D319/18 , C07D333/54
摘要： The anthranilic acid derivative or the salt thereof represented by the general formula wherein R1 and R2 are hydrogen atom, or the like; R3 is a phenyl, cycloalkyl or bicyclic heterocyclic group which may be substituted, or the like; R4 is a phenyl, cycloalkyl or pyridyl group which may be substituted, or the like; X1 is an alkylene or alkenylene group which may be substituted or a bond; X2 is the general formula -X3-X4- or -X4-X3-, wherein X3 is a sulfur atom, an imino group or a bond, or the like; X4 means an alkylene or alkenylene group which may be substituted or a bond; is useful for a remedy such as rheumatoid arthritis, osteoarthritis and carcinoma, because it shows MMP-13 production inhibitory effect.
摘要翻译：由通式表示的邻氨基苯甲酸衍生物或其盐，其中R1和R2是氢原子等; R3是可以被取代的苯基，环烷基或双环杂环基等; R4是可被取代的苯基，环烷基或吡啶基等; X1是可以被取代的或亚烷基的亚烷基或亚烯基; X2是通式-X3-X4-或-X4-X3-，其中X3是硫原子，亚氨基或键等; X 4表示可以被取代或键合的亚烷基或亚烯基; 对于诸如类风湿性关节炎，骨关节炎和癌症的治疗有用，因为它显示MMP-13产生抑制作用。

10. 发明授权

US08796033B2 Method of determining minute amounts of additives in polymers 有权
标题翻译：测定聚合物中微量添加剂的方法
公开(公告)号：US08796033B2
公开(公告)日：2014-08-05
申请号：US10576254
申请日：2004-10-14
申请人： Jiro Naka , Hiroshi Kurokawa , Junji Kobayashi , Satoru Toyama , Noriko Hirano , Eiji Hara
发明人： Jiro Naka , Hiroshi Kurokawa , Junji Kobayashi , Satoru Toyama , Noriko Hirano , Eiji Hara
IPC分类号： G01N33/44 , G01N1/40 , G01N30/00
CPC分类号： G01N1/4055 , G01N33/442 , G01N2001/4061 , G01N2030/009 , Y10T436/24
摘要： A method for analyzing a minute quantity of a material included in a different material is performed in short extraction treatment without taking a long time and the minute content is rapidly analyzed. The method of analyzing a minute content includes mounting on a sample table a sample piece of a material having a minute content of a different material to be analyzed; dropping onto the sample table a solvent for extracting the minute content from the sample piece, so that the solvent is disposed between the sample table and the sample piece; maintaining at room temperature the solvent between the sample table and the sample piece, and, with the solvent maintained between the sample table and the sample piece, extracting the material of the minute content from the sample piece; and analyzing the content extracted from the sample piece.
摘要翻译：用于分析不同材料中所含材料的微量的方法在短时间提取处理中进行，而不需要较长时间并且分析内容得到快速分析。分析微小内容的方法包括在样品台上安装具有不同材料的微量含量的待分析材料的样品片; 在样品台上滴加用于从样品片中提取微量的溶剂，使溶剂置于样品台和样品片之间; 在室温下保持样品台和样品片之间的溶剂，并将溶剂保持在样品台和样品片之间，从样品中提取微量的物质; 并分析从样品片提取的内容。

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