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1. 发明授权

US5875799A Therapeutic dental floss for treating systemic diseases 失效
标题翻译：用于治疗全身性疾病的治疗性牙线
公开(公告)号：US5875799A
公开(公告)日：1999-03-02
申请号：US935841
申请日：1997-09-23
申请人： Edward J. Petrus
发明人： Edward J. Petrus
IPC分类号： A61C15/02 , A61C15/04 , A61C19/06 , A61C15/00
CPC分类号： A61C15/02 , A61C15/041 , A61C19/066
摘要： A method of treating systemic afflictions includes loading a dental floss with an active therapeutic agents and rubbing the floss against a mouth tissue to release the active therapeutic agent onto the tissue for penetration through the tissue. The active therapeutic agent is selected from the group consisting of zinc sulfate, zinc chloride, zinc acetate, zinc phenol sulfonate, zinc borate, zinc bromide, zinc nitrate, zinc glycerophosphate, zinc benzoate, zinc carbonate, zinc citrate, zinc hexafluorosilicate, zinc diacetate trihydrate, zinc oxide, zinc peroxide, zinc salicylate, zinc silicate, zinc stannate, zinc tannate, zinc titanate, zinc tetrafluoroborate, zinc gluconate, and zinc glycinate. An additional therapeutic agent may also be loaded on the floss, for example, antimicrobials, antibiotics, antioxidants, anti-plaque agents, analgesics, anti-tarter agents, anti-caries agents, hemostatic agents, anti-inflammatory agents, hormones, bleaching agents and vitamins.
摘要翻译：一种治疗系统性疾病的方法包括用活性治疗剂加载牙线并将牙线摩擦口腔组织以将活性治疗剂释放到组织上以穿透组织。活性治疗剂选自硫酸锌，氯化锌，乙酸锌，苯酚磺酸锌，硼酸锌，溴化锌，硝酸锌，甘油磷酸锌，苯甲酸锌，碳酸锌，柠檬酸锌，六氟硅酸锌，二乙酸锌三水合物，氧化锌，过氧化锌，水杨酸锌，硅酸锌，锡酸锌，鞣酸锌，钛酸锌，四氟硼酸锌，葡萄糖酸锌和甘氨酸锌。还可以在牙线上加载另外的治疗剂，例如抗微生物剂，抗生素，抗氧化剂，抗斑块剂，止痛剂，抗震剂，抗龋剂，止血剂，抗炎剂，激素，漂白剂和维生素。

2. 发明授权

US5965137A Insect repellent composition and method for inhibiting the transmission and treatment of symptoms of vector-borne diseases 失效
标题翻译：驱虫剂组合物和抑制载体传播疾病症状传播和治疗的方法
公开(公告)号：US5965137A
公开(公告)日：1999-10-12
申请号：US192421
申请日：1998-11-16
申请人： Edward J. Petrus
发明人： Edward J. Petrus
IPC分类号： A61K8/27 , A61K8/67 , A61K8/92 , A61K33/30 , A61K36/00 , A61K36/15 , A61K36/23 , A61K36/235 , A61K36/28 , A61K36/282 , A61K36/45 , A61K36/53 , A61K36/534 , A61K36/54 , A61K36/55 , A61K36/57 , A61K36/61 , A61K36/67 , A61K36/736 , A61K36/738 , A61K36/752 , A61K36/9064 , A61K36/9066 , A61K36/9068 , A61Q17/00 , A61K35/78
CPC分类号： A61Q17/00 , A61K33/30 , A61K36/15 , A61K36/23 , A61K36/235 , A61K36/28 , A61K36/282 , A61K36/45 , A61K36/53 , A61K36/534 , A61K36/54 , A61K36/55 , A61K36/57 , A61K36/61 , A61K36/67 , A61K36/736 , A61K36/738 , A61K36/752 , A61K36/9064 , A61K36/9066 , A61K36/9068 , A61K8/27 , A61K8/671 , A61K8/922
摘要： A topical composition for the delivery of bio-affecting agents through the protective outer layer of skin into the underlying tissues and into the general circulation to prevent the causes and symptoms of vector-borne diseases. The transdermal penetration is achieved by the use of an essential volatile oil with insect repellent capabilities, such as eucalyptus oil. The bio-affective agents may be a combination of a zinc salt and form of vitamin A. A zinc salt may also be used for photoprotective purposes. The topical composition can be formulated as a solution, suspension, cream, ointment, gel, film or spray.
摘要翻译：用于将生物影响剂通过皮肤的保护性外层输送到下面的组织中并进入一般循环以防止载体传播疾病的原因和症状的局部组合物。通过使用具有驱虫能力的必需挥发油，例如桉树油，实现透皮渗透。生物影响剂可以是锌盐和维生素A的形式的组合。锌盐也可以用于光保护目的。局部组合物可以配制成溶液，悬浮液，霜剂，软膏，凝胶，薄膜或喷雾剂。

3. 发明授权

US07136820B1 Method/process of determining a personal dietary supplement profile and recommending dietary supplements for an individual 有权
标题翻译：确定个人膳食补充剂配置文件的方法/过程，并为个人推荐膳食补充剂
公开(公告)号：US07136820B1
公开(公告)日：2006-11-14
申请号：US09444660
申请日：1999-11-22
申请人： Edward J. Petrus
发明人： Edward J. Petrus
IPC分类号： G06F19/00
CPC分类号： G06F19/3475 , G06F19/00 , G06Q50/24
摘要： This invention provides a method/process of determining a personal dietary supplement profile of vitamins, minerals, amino acids, enzymes, herbs, and other nutritional supplements for an individual based on information from a health questionnaire and comparing the individual's health information to an ideal health profile in a computer data base. Optionally, information provided by physical examination and laboratory studies can be incorporated into the method/process of determining the dietary supplement profile. The profile can be further defined by listing commercially available products that provide the suggested dietary supplements.
摘要翻译：本发明提供了一种基于来自健康问卷的信息来确定个体的维生素，矿物质，氨基酸，酶，草药和其他营养补充剂的个人膳食补充剂概况的方法/过程，并将个体的健康信息与理想健康配置文件在计算机数据库中。任选地，通过身体检查和实验室研究提供的信息可以并入确定膳食补充剂特征的方法/过程中。可以通过列出提供建议的膳食补充剂的市售产品来进一步定义轮廓。

4. 发明授权

US06573299B1 Method and compositions for treatment of the aging eye 失效
标题翻译：治疗老化眼睛的方法和组合物
公开(公告)号：US06573299B1
公开(公告)日：2003-06-03
申请号：US09399393
申请日：1999-09-20
申请人： Edward J. Petrus
发明人： Edward J. Petrus
IPC分类号： A61K3120
CPC分类号： A61K9/0048 , A61K31/19 , A61K31/194 , A61K31/20 , A61K45/06
摘要： This invention relates to a method for the prevention and treatment of orbital disorders associated with the aging eye in mammals by the application of a topical composition comprising a permeation enhancing amount of one or more penetration enhancers, and one or more bio-affecting agents which penetrate into the underlying tissues and into the vascular network of the orbit. Another object of this invention is the improvement of age-related changes to the eyelids such as dry skin, wrinkles, keratoses, age spots and pigmented skin lesions. It is a further object of this invention to prevent and treat cataract formation, glaucoma, diabetic retinopathy and macular degeneration.
摘要翻译：本发明涉及通过施用包含渗透促进量的一种或多种渗透增强剂的局部组合物和一种或多种渗透促进剂的一种或多种生物影响剂来预防和治疗与哺乳动物的老化眼睛相关的眼眶疾病的方法进入下面的组织并进入轨道的血管网络。本发明的另一个目的是改善眼皮的年龄相关变化，例如干性皮肤，皱纹，角化病，老年斑和色素沉着的皮肤病变。本发明的另一个目的是预防和治疗白内障形成，青光眼，糖尿病性视网膜病变和黄斑变性。

5. 发明授权

US06399093B1 Method and composition to treat musculoskeletal disorders 失效
标题翻译：治疗肌肉骨骼疾病的方法和组成
公开(公告)号：US06399093B1
公开(公告)日：2002-06-04
申请号：US09314829
申请日：1999-05-19
申请人： Edward J. Petrus
发明人： Edward J. Petrus
IPC分类号： A61L1516
CPC分类号： A61K9/0014 , A61K31/165 , A61K31/192 , A61K31/196 , A61K45/06 , A61K47/10 , A61K47/20 , A61K47/32
摘要： A method and composition for the treatment of musculoskeletal disorders in mammals by the application of a topical composition comprising a permeation enhancing amount of one or more penetration enhancers, and one or more bio-affecting agents to provide anti-inflammatory relief and analgesia to the applied body part.
摘要翻译：一种用于治疗哺乳动物肌肉骨骼疾病的方法和组合物，其通过使用包含渗透促进量的一种或多种渗透促进剂的局部组合物和一种或多种生物影响剂来提供抗炎减轻和镇痛身体的一部分。

6. 发明授权

US06346519B1 Method and composition for treating arthritis 失效
标题翻译：用于治疗关节炎的方法和组合物
公开(公告)号：US06346519B1
公开(公告)日：2002-02-12
申请号：US09350380
申请日：1999-07-08
申请人： Edward J. Petrus
发明人： Edward J. Petrus
IPC分类号： A61K3173
CPC分类号： A61K31/7004 , A61K45/06 , Y10S514/825 , Y10S514/885 , A61K2300/00 , A61K31/195
摘要： This invention relates to the composition and method of treating arthritis, repairing of articular joint surfaces and the relief of symptoms associated with arthritis. The composition comprises a nitric oxide synthase inhibitor and amino sugars. The nitric oxide synthase inhibitor reduces the level of nitric oxide, the free radical believed responsible for the degradation of articular cartilage. Amino sugars are the building blocks of articular cartilage and have anti-inflammatory actions.
摘要翻译：本发明涉及治疗关节炎的组合物和方法，关节关节表面的修复以及与关节炎相关症状的缓解。该组合物包含一氧化氮合酶抑制剂和氨基糖。一氧化氮合酶抑制剂降低一氧化氮的水平，认为自由基负责关节软骨的降解。氨基糖是关节软骨的组成部分，具有抗炎作用。

7. 发明授权

US6093417A Composition to treat ear disorders 有权
标题翻译：组合治疗耳部疾病
公开(公告)号：US6093417A
公开(公告)日：2000-07-25
申请号：US228119
申请日：1999-01-11
申请人： Edward J. Petrus
发明人： Edward J. Petrus
IPC分类号： A61K9/00 , A61K36/886 , A61K45/06 , A61K31/495 , A61K31/56
CPC分类号： A61K9/0046 , A61K45/06
摘要： A topical ear composition that uses penetration enhancers to diffuse the therapeutic agents through the tympanic membrane into the middle and inner ear for the purpose of reducing the inflammation of ear tissues, providing pain relief, and introducing agents with antimicrobial activity to combat infection. The composition reduces swelling of the lining membranes of the middle and inner ear, prevent the destructive effects of inflamation, inhibit the production of prostaglandins, reduce symptoms of tinnitus and vertigo, improve and prevent paralysis of the facial nerve, relieve labyrinthitis, and prevent hearing loss.
摘要翻译：一种局部耳用组合物，其使用渗透促进剂将治疗剂通过鼓膜扩散到中耳和内耳中，以减少耳朵组织的炎症，提供疼痛缓解，并引入具有抗菌活性以抵抗感染的药剂。该组合物减少中耳内耳膜的肿胀，防止炎症的破坏作用，抑制前列腺素的产生，减轻耳鸣和眩晕症状，改善和预防面神经麻痹，缓解迷路炎，防止听觉失利。

8. 发明授权

US5954682A Therapeutic applicator apparatus and method 失效
标题翻译：治疗敷料器及方法
公开(公告)号：US5954682A
公开(公告)日：1999-09-21
申请号：US721588
申请日：1996-09-25
申请人： Edward J. Petrus
发明人： Edward J. Petrus
IPC分类号： A61F13/38 , A61M31/00 , A61M35/00 , A61F13/20
CPC分类号： A61F11/00 , A61F13/38 , A61M31/00
摘要： A therapeutic applicator comprises a porous media, a string attached to the porous media, and a hollow tube, having a first end and a second end. The string passes through the hollow tube and exits the hollow tube at the first end when the porous media is positioned in proximity of the second end. A therapeutic agent is impregnated in the porous media.
摘要翻译：治疗施用器包括多孔介质，连接到多孔介质的串和具有第一端和第二端的中空管。当多孔介质位于第二端附近时，绳穿过中空管并在第一端离开中空管。在多孔介质中浸渍治疗剂。

9. 发明授权

US5875798A Therapeutic toothpick for treating oral and systemic diseases 失效
标题翻译：用于治疗口腔和全身疾病的治疗牙签
公开(公告)号：US5875798A
公开(公告)日：1999-03-02
申请号：US085767
申请日：1998-05-28
申请人： Edward J. Petrus
发明人： Edward J. Petrus
IPC分类号： A61C15/02 , A61C15/04 , A61C19/06 , A61C15/00
CPC分类号： A61C15/02 , A61C15/041 , A61C19/066
摘要： A method of treating oral and systemic diseases includes impregnating or coating a toothpick with active therapeutic agents and rubbing the toothpick against mouth tissue to release the active therapeutic agents onto the tissue for penetration through the tissue. The active therapeutic agent is selected from the group consisting of, but not limited to: zinc sulfate, zinc chloride, zinc acetate, zinc phenol sulfonate, zinc borate, zinc bromide, zinc nitrate, zinc glycerophosphate, zinc benzoate, zinc carbonate, zinc citrate, zinc hexafluorosilicate, zinc diacetate trihydrate, zinc oxide, zinc peroxide, zinc salicylate, zinc silicate, zinc stannate, zinc tannate, zinc titanate, zinc tetrafluoroborate, zinc gluconate, and zinc glycinate. An additional therapeutic agent may also be impregnated or coated on the toothpick, for example, antimicrobials, antibiotics, antioxidants, anti-plaque agents, analgesics, anti-tartar agents, anti-caries agents, hemostatic agents, anti-inflammatory agents, hormones, bleaching agents, vitamins, vaccines, caffeine and monoclonal antibodies.
摘要翻译：治疗口腔和全身疾病的方法包括用活性治疗剂浸渍或涂覆牙签并将牙签摩擦口腔组织以将活性治疗剂释放到组织上以穿透组织。活性治疗剂选自但不限于：硫酸锌，氯化锌，乙酸锌，苯酚磺酸锌，硼酸锌，溴化锌，硝酸锌，甘油磷酸锌，苯甲酸锌，碳酸锌，柠檬酸锌，六氟硅酸锌，二乙酸锌三水合物，氧化锌，过氧化锌，水杨酸锌，硅酸锌，锡酸锌，鞣酸锌，钛酸锌，四氟硼酸锌，葡萄糖酸锌和甘氨酸锌。也可以在牙签上浸渍或涂覆另外的治疗剂，例如抗微生物剂，抗生素，抗氧化剂，抗斑块剂，止痛剂，抗牙垢剂，抗龋剂，止血剂，抗炎剂，激素，漂白剂，维生素，疫苗，咖啡因和单克隆抗体。

10. 发明授权

US5417224A Tampon and method for manufacturing the same 失效
标题翻译：棉塞及其制造方法
公开(公告)号：US5417224A
公开(公告)日：1995-05-23
申请号：US63906
申请日：1993-05-19
申请人： Edward J. Petrus , Maurice S. Conte
发明人： Edward J. Petrus , Maurice S. Conte
IPC分类号： A61F6/08 , A61F13/20 , A61F13/34 , A61L15/44 , A61L15/46 , A61F6/06 , A61F13/15
CPC分类号： A61F13/2048 , A61F13/34 , A61F6/08 , A61L15/44 , A61L15/46 , Y10S128/918 , Y10S604/904
摘要： An improved tampon is provided having one or more loops placed entirely through the tampon for ease in insertion and removal of an attached spherical member into and from a body cavity. Moreover, the improved tampon can be impregnated at select depths with specific spermicides, anti-infectives, lubricants, hormones, antioxidants, amino acids, etc., to allow release of inner-impregnated fluids from the member into the body cavity. Closely controlled impregnation and/or coating of the tampon is achieved by a method of manufacture employing one or more sonic baths containing necessary impregnating and/or coating fluids.
摘要翻译：提供了一种改进的卫生棉条，其具有完全穿过卫生棉条的一个或多个环，以便于将附接的球形构件插入和移出体腔。此外，改进的卫生棉条可以用特定的杀精剂，抗感染剂，润滑剂，激素，抗氧化剂，氨基酸等浸渍在选定的深度，以允许内浸性流体从构件释放到体腔中。通过采用含有必需浸渍和/或涂布液体的一个或多个声音浴的制造方法来实现棉塞的紧密控制浸渍和/或涂覆。

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