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1. 发明申请

US20120197273A1 ENDOSCOPIC TISSUE APPOSITION DEVICE WITH MULTIPLE SUCTION PORTS 审中-公开
标题翻译：具有多个吸气口的内窥镜组织检查装置
公开(公告)号：US20120197273A1
公开(公告)日：2012-08-02
申请号：US13441304
申请日：2012-04-06
申请人： Richard A. Gambale , Michael F. Weiser , Edward C. Page , Peter J. Lukin
发明人： Richard A. Gambale , Michael F. Weiser , Edward C. Page , Peter J. Lukin
IPC分类号： A61B17/11
CPC分类号： A61B17/0469 , A61B17/00234 , A61B17/0401 , A61B17/0482 , A61B17/0625 , A61B17/068 , A61B17/08 , A61B18/1492 , A61B2017/00827 , A61B2017/0409 , A61B2017/0417 , A61B2017/0458 , A61B2017/047 , A61B2017/0472 , A61B2017/061 , A61B2017/081 , A61B2017/306 , A61B2018/00291
摘要： The present invention relates to an improved endoscopic tissue apposition device having multiple suction ports. The invention permits multiple folds of tissue to be captured in the suction ports with a single positioning of the device and attached together by a tissue securement mechanism such as a suture, staple or other form of tissue bonding. The improvement reduces the number of intubations required during an endoscopic procedure to suture tissue or join areas of tissue together. The suction ports may be arranged in a variety of configurations on the apposition device to best suit the desired resulting tissue orientation. The inventive tissue apposition device may also incorporate tissue abrasion means to activate the healing process on surfaces of tissue areas that are to be joined by operation of the device to promote a more secure attachment by permanent tissue bonding.
摘要翻译：本发明涉及具有多个吸入口的改进的内窥镜组织接合装置。本发明允许组织的多个折叠在装置的单个定位中被捕获在吸入口中，并通过组织固定机构（例如缝合线，钉或其它形式的组织结合）附接在一起。该改进减少了在内窥镜过程中将缝合组织或将组织区域连接在一起的插管数量。吸入口可以以配置装置中的各种构造布置，以最适合所需的组织取向。本发明的组织接合装置还可以包括组织磨损装置，以通过装置的操作来激活要连接的组织区域的表面上的愈合过程，以通过永久性组织结合来促进更安全的附接。

2. 发明申请

US20080215069A1 Endoscopic tissue apposition device with multiple suction ports 有权
标题翻译：具有多个吸入口的内窥镜组织安置装置
公开(公告)号：US20080215069A1
公开(公告)日：2008-09-04
申请号：US12070809
申请日：2008-02-21
申请人： Richard A. Gambale , Michael F. Weiser , Edward C. Page , Peter J. Lukin
发明人： Richard A. Gambale , Michael F. Weiser , Edward C. Page , Peter J. Lukin
IPC分类号： A61B17/04
CPC分类号： A61B17/0401 , A61B17/00234 , A61B17/0469 , A61B17/0482 , A61B17/0625 , A61B17/068 , A61B17/08 , A61B18/1492 , A61B18/22 , A61B2017/00827 , A61B2017/0409 , A61B2017/0417 , A61B2017/0458 , A61B2017/047 , A61B2017/0472 , A61B2017/061 , A61B2017/081 , A61B2017/306 , A61B2018/00291
摘要： The present invention relates to an improved endoscopic tissue apposition device having multiple suction ports. The invention permits multiple folds of tissue to be captured in the suction ports with a single positioning of the device and attached together by a tissue securement mechanism such as a suture, staple or other form of tissue bonding. The improvement reduces the number of intubations required during an endoscopic procedure to suture tissue or join areas of tissue together. The suction ports may be arranged in a variety of configurations on the apposition device to best suit the desired resulting tissue orientation. The inventive tissue apposition device may also incorporate tissue abrasion means to activate the healing process on surfaces of tissue areas that are to be joined by operation of the device to promote a more secure attachment by permanent tissue bonding.
摘要翻译：本发明涉及具有多个吸入口的改进的内窥镜组织接合装置。本发明允许组织的多个折叠在装置的单个定位中被捕获在吸入口中，并通过组织固定机构（例如缝合线，钉或其它形式的组织结合）附接在一起。该改进减少了在内窥镜过程中将缝合组织或将组织区域连接在一起的插管数量。吸入口可以以配置装置中的各种构造布置，以最适合所需的组织取向。本发明的组织接合装置还可以包括组织磨损装置，以通过装置的操作来激活要连接的组织区域的表面上的愈合过程，以通过永久性组织结合来促进更安全的附接。

3. 发明授权

US08206284B2 Integrated endoscope and accessory treatment device 有权
标题翻译：一体化内窥镜及附件处理装置
公开(公告)号：US08206284B2
公开(公告)日：2012-06-26
申请号：US12725283
申请日：2010-03-16
申请人： Harold M. Aznoian , Richard L. Costa , John Dimitriou , Richard A. Gambale , Peter J. Lukin , Edward C. Page , Sean J. Silva , David T. Zelonis
发明人： Harold M. Aznoian , Richard L. Costa , John Dimitriou , Richard A. Gambale , Peter J. Lukin , Edward C. Page , Sean J. Silva , David T. Zelonis
IPC分类号： A61B1/00
CPC分类号： A61B17/0482 , A61B1/00087 , A61B1/018 , A61B17/0469 , A61B17/0643 , A61B90/361 , A61B2017/00296 , A61B2017/306
摘要： An integrated endoscope and accessory treatment device is provided. The device employs a medical treatment device at its distal end that is combined with the endoscope as a complete system. The treatment device is controlled by integrated elements at the proximal end of the endoscope. The treatment devices may include tissue apposition devices, tissue cutting devices, forceps and others.
摘要翻译：提供一体化内窥镜和附件处理装置。该装置在其远端采用与内窥镜组合的医疗装置作为完整系统。治疗装置由内窥镜近端的集成元件控制。治疗装置可以包括组织安置装置，组织切割装置，镊子等。

4. 发明授权

US08105355B2 Suture lock fastening device 有权
标题翻译：缝合锁紧固装置
公开(公告)号：US08105355B2
公开(公告)日：2012-01-31
申请号：US11436398
申请日：2006-05-18
申请人： Edward C. Page , Patrick Gutelius , Danial Ferreira , Jeffrey Radziunas , Paul Dicesare
发明人： Edward C. Page , Patrick Gutelius , Danial Ferreira , Jeffrey Radziunas , Paul Dicesare
IPC分类号： A61B17/04
CPC分类号： A61B17/0487 , A61B17/0467 , A61B17/0485 , A61B2017/045 , A61B2017/0488
摘要： A suture lock fastening device to cinch a suture in a suture lock, cut the suture end, and deploy the suture lock in response to a single movement of a user. The fastening device includes a fastening head with a retainer that is configured to hold a suture lock in the fastening head. To release the suture lock from the fastening head, the retainer is irreversibly deformed. The fastening device may include an axially movable cutter with a cutting edge to sever the ends of the suture close to the suture lock. A threading device may be preloaded into the fastening device to facilitate threading the suture through the fastening device.
摘要翻译：一种缝合线锁紧装置，用于将缝合线缝合在缝合线锁中，切割缝合线端部，并且响应于使用者的单次运动而部署缝合线锁。紧固装置包括具有保持器的紧固头部，该保持器构造成将缝合线锁定在紧固头部中。为了从紧固头释放缝合线锁，保持架不可逆地变形。紧固装置可以包括具有切割刃的可轴向移动的切割器，以将缝合线的端部切割成靠近缝合线锁定。穿线装置可以被预加载到紧固装置中以便于缝合线穿过紧固装置。

5. 发明申请

US20080234729A1 Suture lock fastening device 有权
标题翻译：缝合锁紧固装置
公开(公告)号：US20080234729A1
公开(公告)日：2008-09-25
申请号：US11436398
申请日：2006-05-18
申请人： Edward C. Page , Patrick Gutelius , Danial Ferreira , Jeffrey Radziunas , Paul Dicesare
发明人： Edward C. Page , Patrick Gutelius , Danial Ferreira , Jeffrey Radziunas , Paul Dicesare
IPC分类号： A61B17/04
CPC分类号： A61B17/0487 , A61B17/0467 , A61B17/0485 , A61B2017/045 , A61B2017/0488
摘要： A suture lock fastening device to cinch a suture in a suture lock, cut the suture end, and deploy the suture lock in response to a single movement of a user. The fastening device includes a fastening head with a retainer that is configured to hold a suture lock in the fastening head. To release the suture lock from the fastening head, the retainer is irreversibly deformed. The fastening device may include an axially movable cutter with a cutting edge to sever the ends of the suture close to the suture lock. A threading device may be preloaded into the fastening device to facilitate threading the suture through the fastening device.
摘要翻译：一种缝合线锁紧装置，用于将缝合线缝合在缝合线锁中，切割缝合线端部，并且响应于使用者的单次运动而部署缝合线锁。紧固装置包括具有保持器的紧固头部，该保持器构造成将缝合线锁定在紧固头部中。为了从紧固头释放缝合锁，保持器不可逆地变形。紧固装置可以包括具有切割刃的可轴向移动的切割器，以将缝合线的端部切割成靠近缝合线锁定。穿线装置可以被预加载到紧固装置中以便于缝合线穿过紧固装置。

6. 发明授权

US6083150A Endoscopic multiple sample biopsy forceps 有权
标题翻译：内窥镜多个样本活检钳
公开(公告)号：US6083150A
公开(公告)日：2000-07-04
申请号：US268138
申请日：1999-03-12
申请人： Harold M. Aznoian , Frank V Patterson , Peter J. Lukin , John E. Dimitriou , Steven L. Lantagne , Edward C. Page
发明人： Harold M. Aznoian , Frank V Patterson , Peter J. Lukin , John E. Dimitriou , Steven L. Lantagne , Edward C. Page
IPC分类号： A61B10/06 , A61B1/00 , A61B10/00 , A61B10/02 , A61B17/28
CPC分类号： A61B10/06 , A61B2010/0225 , A61B2017/2936
摘要： A endoscopic multiple sample biopsy forceps is disclosed having a jaw assembly with a pair of jaws connected to a pair of arms extending from a jaw housing. Each jaw has two shanks oppositely displaced from the longitudinal axis of the device to define a space in the rear of the jaw for storing collected tissue samples. The tissue storage space defined by the jaw shanks opens rearwardly into a tissue storage area defined within the housing. Each shank has a broad outwardly facing planar surface aligned with an inwardly facing planar surface on one of the pair of arms. A cam slot on each jaw shank is slidably engaged by a cam pin on one of the pair of arms. A puller member coaxially positioned in the housing and axially movable relative to the housing supports a pair of pivots, each of which pivotally engages a bore on at least one jaw shank. The puller member is attached to a drive wire coaxially positioned in a tubular shaft. Axial movement of the drive wire actuates the puller member. In response to axial movement of the puller along the longitudinal axis of the outer tube, the cam pins riding in the cam guide slots change the position relative to the fixed jaw pivot axis of the jaw, thus actuating the jaws. None of the jaw assembly elements movable relative to the device, except the jaws, are externally exposed such that they could contact targeted tissue and negatively affect tissue sampling operations. An ejector is provided to push collected samples from the tissue sample storage area.
摘要翻译：公开了一种内窥镜多样本活检钳，其具有钳口组件，其具有连接到从钳口壳体延伸的一对臂的一对钳口。每个钳口具有两个与装置的纵向轴线相对移位的柄部，以在钳口的后部限定一个用于存储收集的组织样本的空间。由爪柄限定的组织存储空间向后打开到限定在壳体内的组织存储区域中。每个柄具有与该对臂中的一个上的向内面对的平坦表面对准的宽的向外的平坦表面。每个钳口柄上的凸轮槽可以通过一对臂之一上的凸轮销滑动地接合。同轴地定位在壳体中并且相对于壳体可轴向移动的拉杆构件支撑一对枢轴，每个枢轴枢转地接合在至少一个夹爪上的孔。牵引构件附接到同轴地定位在管状轴中的驱动线。驱动线的轴向运动促动拉杆构件。响应于拉动器沿着外管的纵向轴线的轴向运动，骑在凸轮引导槽中的凸轮销相对于钳口的固定夹爪枢转轴线改变位置，从而致动钳口。没有钳口组件元件相对于装置可移动，除了钳口外，其外露，使得它们可以接触目标组织并且不利地影响组织取样操作。提供喷射器以从组织样品存储区域推送收集的样品。

7. 发明授权

US08152821B2 Endoscopic tissue apposition device with multiple suction ports 有权
公开(公告)号：US08152821B2
公开(公告)日：2012-04-10
申请号：US12070809
申请日：2008-02-21
申请人： Richard A. Gambale , Michael F. Weiser , Edward C. Page , Peter J. Lukin
发明人： Richard A. Gambale , Michael F. Weiser , Edward C. Page , Peter J. Lukin
IPC分类号： A61B17/10 , A61B17/04
CPC分类号： A61B17/0401 , A61B17/00234 , A61B17/0469 , A61B17/0482 , A61B17/0625 , A61B17/068 , A61B17/08 , A61B18/1492 , A61B18/22 , A61B2017/00827 , A61B2017/0409 , A61B2017/0417 , A61B2017/0458 , A61B2017/047 , A61B2017/0472 , A61B2017/061 , A61B2017/081 , A61B2017/306 , A61B2018/00291
摘要： The present invention relates to an improved endoscopic tissue apposition device having multiple suction ports. The invention permits multiple folds of tissue to be captured in the suction ports with a single positioning of the device and attached together by a tissue securement mechanism such as a suture, staple or other form of tissue bonding. The improvement reduces the number of intubations required during an endoscopic procedure to suture tissue or join areas of tissue together. The suction ports may be arranged in a variety of configurations on the apposition device to best suit the desired resulting tissue orientation. The inventive tissue apposition device may also incorporate tissue abrasion means to activate the healing process on surfaces of tissue areas that are to be joined by operation of the device to promote a more secure attachment by permanent tissue bonding.

8. 发明申请

US20100174140A1 INTEGRATED ENDOSCOPE AND ACCESSORY TREATMENT DEVICE 有权
标题翻译：综合内窥镜和附件治疗装置
公开(公告)号：US20100174140A1
公开(公告)日：2010-07-08
申请号：US12725283
申请日：2010-03-16
申请人： Harold M. Aznoian , Richard L. Costa , John E. Dimitriou , Richard A. Gambale , Peter J. Lukin , Edward C. Page , Sean J. Silva , David T. Zelonis
发明人： Harold M. Aznoian , Richard L. Costa , John E. Dimitriou , Richard A. Gambale , Peter J. Lukin , Edward C. Page , Sean J. Silva , David T. Zelonis
IPC分类号： A61B17/84 , A61B17/06
CPC分类号： A61B17/0482 , A61B1/00087 , A61B1/018 , A61B17/0469 , A61B17/0643 , A61B90/361 , A61B2017/00296 , A61B2017/306
摘要： An integrated endoscope and accessory treatment device is provided. The device employs a medical treatment device at its distal end that is combined with the endoscope as a complete system. The treatment device is controlled by integrated elements at the proximal end of the endoscope. The treatment devices may include tissue apposition devices, tissue cutting devices, forceps and others.
摘要翻译：提供一体化内窥镜和附件处理装置。该装置在其远端采用与内窥镜组合的医疗装置作为完整系统。治疗装置由内窥镜近端的集成元件控制。治疗装置可以包括组织安置装置，组织切割装置，镊子等。

9. 发明授权

US07399304B2 Endoscopic tissue apposition device with multiple suction ports 有权
标题翻译：具有多个吸入口的内窥镜组织安置装置
公开(公告)号：US07399304B2
公开(公告)日：2008-07-15
申请号：US10220379
申请日：2001-03-02
申请人： Richard A. Gambale , Michael F. Weiser , Edward C. Page , Peter J. Lukin
发明人： Richard A. Gambale , Michael F. Weiser , Edward C. Page , Peter J. Lukin
IPC分类号： A61B17/10 , A61B17/04 , A61B18/18
CPC分类号： A61B17/0401 , A61B17/00234 , A61B17/0469 , A61B17/0482 , A61B17/0625 , A61B17/068 , A61B17/08 , A61B18/1492 , A61B18/22 , A61B2017/00827 , A61B2017/0409 , A61B2017/0417 , A61B2017/0458 , A61B2017/047 , A61B2017/0472 , A61B2017/061 , A61B2017/081 , A61B2017/306 , A61B2018/00291
摘要： An improved endoscopic tissue apposition device (50) having multiple suction ports (86) permits multiple folds of tissue to be captured in the suction ports (86) with a single positioning of the device (50) and attached together by a tissue securement mechanism such as a suture (14), staple or other form of tissue bonding. The improvement reduces the number of intubations required during an endoscopic procedure to suture tissue or join areas of tissue together. The suction ports (86) may be arranged in a variety of configurations on the apposition device (50) to best suit the desired resulting tissue orientation. The tissue apposition device (50) may also incorporate tissue abrasion means (852) to activate the healing process on surfaces of tissue areas that are to be joined by operation of the device to promote a more secure attachment by permanent tissue bonding.
摘要翻译：具有多个吸入口（86）的改进的内窥镜组织安置装置（50）允许组织的多个折叠通过装置（50）的单个定位被捕获在吸入口（86）中，并且通过组织固定机构作为缝合线（14），钉或其他形式的组织粘合。该改进减少了在内窥镜过程中将缝合组织或将组织区域连接在一起的插管数量。吸入口（86）可以以各种配置布置在接合装置（50）上，以最适合所需的组织取向。组织安置装置（50）还可以包括组织磨损装置（852），以通过装置的操作来激活要连接的组织区域的表面上的愈合过程，以通过永久性组织粘合促进更安全的附接。

10. 发明申请

US20080147096A1 Integrated endoscope and accessory treament device 有权
标题翻译：一体化内窥镜和附件处理装置
公开(公告)号：US20080147096A1
公开(公告)日：2008-06-19
申请号：US12072441
申请日：2008-02-26
申请人： Harold M. Aznoian , Richard L. Costa , John E. Dimitriou , Richard A. Gambale , Peter J. Lukin , Edward C. Page , Sean J. Silva , David T. Zelonis
发明人： Harold M. Aznoian , Richard L. Costa , John E. Dimitriou , Richard A. Gambale , Peter J. Lukin , Edward C. Page , Sean J. Silva , David T. Zelonis
IPC分类号： A61B17/04
CPC分类号： A61B17/0482 , A61B1/00087 , A61B1/018 , A61B17/0469 , A61B17/0643 , A61B90/361 , A61B2017/00296 , A61B2017/306
摘要： An integrated endoscope and accessory treatment device is provided. The device employs a medical treatment device at its distal end that is combined with the endoscope as a complete system. The treatment device is controlled by integrated elements at the proximal end of the endoscope. The treatment devices may include tissue apposition devices, tissue cutting devices, forceps and others.
摘要翻译：提供一体化内窥镜和附件处理装置。该装置在其远端采用与内窥镜组合的医疗装置作为完整系统。治疗装置由内窥镜近端的集成元件控制。治疗装置可以包括组织安置装置，组织切割装置，镊子等。

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