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1. 发明授权

US5110599A Process for producing an administration and/or dosage form for medicinal active substances by means of a printing process 失效
标题翻译：通过印刷过程生产药物活性物质的管理和/或剂型的方法
公开(公告)号：US5110599A
公开(公告)日：1992-05-05
申请号：US746296
申请日：1991-08-13
申请人： Dieter Anhauser , Robert-Peter Klein
发明人： Dieter Anhauser , Robert-Peter Klein
IPC分类号： A61K9/44 , A61J3/00 , A61J3/10 , A61K9/70 , A61K31/465 , B41F17/00 , B41F17/34 , B41M1/40
CPC分类号： B41F17/001 , A61J3/10 , A61K9/70 , A61K9/7084
摘要： The invention relates to a process for producing an administration and/or dosage form for medicament active substances using a printing process, in which the printing process used is a pad printing process.
摘要翻译：本发明涉及使用印刷方法制备药物活性物质的给药和/或剂型的方法，其中使用的印刷方法是移印工艺。

2. 发明授权

US06315854B1 Transdermal therapeutic plaster 失效
标题翻译：透皮治疗膏药
公开(公告)号：US06315854B1
公开(公告)日：2001-11-13
申请号：US08531890
申请日：1995-09-22
申请人： Dieter Anhauser , Lothar Deurer , Thomas Hille , Peter Steinborn
发明人： Dieter Anhauser , Lothar Deurer , Thomas Hille , Peter Steinborn
IPC分类号： B32B3110
CPC分类号： A61K9/7061 , A61F2013/0296 , A61K9/7084 , Y10T156/1052 , Y10T156/108 , Y10T156/1085 , Y10T156/1095
摘要： A process for continuously manufacturing transdermal therapeutic patches having a backing layer, a pressure-sensitive adhesive drug reservoir layer, and a removable protective layer, whereby loss of active substances during fabrication of the patches is minimized, said process being characterized in that, in a tape-like laminate having a pressure-sensitive adhesive backing layer (1) and a removable protective layer (3), single quadrangular pressure-sensitive adhesive drug reservoir sections (2) are inserted one after the other in the longitudinal direction between the layers (2,3); the clearance between said drug reservoir sections remains constant in the longitudinal direction; their width is calculated such that the backing layer (1) and the removable protective layer (3) project beyond both sides of said sections; the pressure-sensitive adhesive backing layer (1) is first cut by punching in such a way that the punching line (1a) surrounds the individual drug reservoir sections (2) at an evident distance from their outer dimensions; the the resulting lattice-type refuse of the drug-free pressure-sensitive adhesive backing layer (1) is removed; and subsequently the protective layer (3) is cut in the resultant spaces between the drug reservoir sections (2).
摘要翻译：一种用于连续制造具有背衬层，压敏粘合剂药物储存层和可移除保护层的透皮治疗贴片的方法，由此在贴片制造过程中活性物质的损失最小化，所述方法的特征在于，具有压敏粘合剂背衬层（1）和可移除保护层（3）的带状层压体，单个四边形压敏粘合剂药物储存部分（2）沿着纵向方向一个接一个地插入在层之间 2,3）; 所述药物储存部之间的间隙在长度方向保持恒定; 计算它们的宽度，使得背衬层（1）和可移除保护层（3）突出超出所述部分的两侧; 首先通过冲压来切割压敏粘合剂背衬层（1），使冲孔线（1a）以与其外部尺寸明显的距离围绕各个药物储存部分（2）; 除去无药物粘合剂背衬层（1）的所得晶格型垃圾; 随后在药物储存部分（2）之间的合成空间中切割保护层（3）。

3. 发明授权

US5569484A Process for producing a flat active substance administration form 失效
标题翻译：生产平面活性物质给药形式的方法
公开(公告)号：US5569484A
公开(公告)日：1996-10-29
申请号：US397167
申请日：1995-05-19
申请人： Walter Muller , Dieter Anhauser
发明人： Walter Muller , Dieter Anhauser
IPC分类号： A61J3/00 , A61K9/26 , A61K9/70 , A61L9/12 , B05D1/28 , B41M3/00 , A01N25/00 , A61J13/00
CPC分类号： A61K9/703 , A61J3/00 , A61K9/70 , A61K9/7038 , A61K9/7092 , A61L9/12 , B05D1/28 , B41M3/006 , A61F2013/0296
摘要： A process is provided for the production of a flat administration form with a dosable portion of drugs or of a flat-shaped device for the dosable release of volatile substances, such as aromatic substances, to the ambient air by using high-volatile or thermolabile dosing media in liquid or semisolid state as the ingredients of the administration form or of the device by means of printing processes. A free-flowing preparation of the ingredients is knife-coated in a measured amount into at least one volumetrically defined cavity of a flat printing block. A substrate to be charged with the ingredients or dosing media, respectively, is gradually led as web-shaped material under web tension over the cavity of the printing block and pressed into the filled cavity by means of a mechanical pressure device whereby the substrate takes up the ingredient from the printing block in a dosed amount.
摘要翻译： PCT No.PCT / EP93 / 02168 Sec。 371日期1995年5月19日 102（e）日期1995年5月19日PCT提交1995年5月19日PCT公布。第WO94 / 06419号公报日期1994年3月31日提供了一种用于生产具有药物部分或扁平形状装置的扁平给药形式的方法，用于通过使用高的剂量将挥发性物质例如芳族物质可释放到周围空气中挥发性或热不稳定的剂量培养基，以液体或半固体状态作为施用形式的成分或通过印刷方法的装置成分。将成分的自由流动的制剂以测量的量涂覆到平坦印刷块的至少一个体积定义的空腔中。要分别装入成分或定量给料介质的基材在卷筒纸张力下逐渐作为卷筒纸材料引导到印刷块的空腔上，并通过机械压力装置压入填充的空腔中，由此基板占据来自打印块的成分以计量量。

4. 发明授权

US4619253A Foil- or film-like bandage and process for using the same 失效
标题翻译：箔或薄膜状绷带及其使用方法
公开(公告)号：US4619253A
公开(公告)日：1986-10-28
申请号：US678782
申请日：1984-12-06
申请人： Dieter Anhauser , Gerhard Kreitlow , Hubertus Olbrich , Karl-Heinz Reinhold , Anita Schmitt
发明人： Dieter Anhauser , Gerhard Kreitlow , Hubertus Olbrich , Karl-Heinz Reinhold , Anita Schmitt
IPC分类号： C09J7/02 , A61F13/00 , A61F13/02 , B05D5/10 , A61L15/00 , B32B27/00 , E04F15/16
CPC分类号： A61F13/023 , A61F2013/00829 , Y10T428/14 , Y10T428/31551
摘要： The invention is related to a foil- or film-like bandage consisting of a transparent continuous bandage foil which on the one side is covered with a transparent supporting foil and on the other side is provided with an adhesive layer and a removable cover layer thereupon, the supporting foil extending over said transparent continuous bandage foil at opposite edges and the cover layer having the same size as the adhesive layer, said cover layer having particularly formed preset cuts or preset breaking lines between two points at different edges, preferably opposite edges such that the cover layer is partitioned into two parts and, upon bending of the foil- or film-like bandage, there is produced an auxiliary pull-off means in the cover layer for the same.
摘要翻译：本发明涉及由透明连续绷带箔构成的箔状或薄膜状的绷带，其一侧被透明的支撑箔覆盖，另一侧在其上设置有粘合剂层和可移除的覆盖层，所述支撑箔在相对边缘处的所述透明连续绷带箔上延伸，并且所述覆盖层具有与所述粘合剂层相同尺寸的所述覆盖层，所述覆盖层在不同边缘处优选相对边缘处的两个点之间具有特别形成的预设切口或预设断裂线，使得覆盖层被分成两部分，并且在箔或膜状绷带弯曲时，在其覆盖层中产生辅助拉脱装置。

5. 发明授权

US6142954A Epicutaneous test plaster 失效
标题翻译：皮肤试验膏药
公开(公告)号：US6142954A
公开(公告)日：2000-11-07
申请号：US319744
申请日：1999-07-15
申请人： Dieter Anhauser , Jurgen Ecker , Heike Schentek
发明人： Dieter Anhauser , Jurgen Ecker , Heike Schentek
IPC分类号： A61B5/00 , A61B10/00 , A61F13/00 , A61F13/02
CPC分类号： A61B10/0035 , A61F13/023 , A61F2013/00434 , A61F2013/00829
摘要： A patch test plaster having at least one active substance receptacle arranged on a backing film, having a highly elastic backing film which is made of polymeric material, is impermeable to liquid water but permeable to water vapour, and is releasibly connected on the surface facing away from the skin to a supporting sheet and is provided on the surface facing the skin with an adhesive layer which is in turn covered by an at least two-part detachable protecting layer before application of the plaster, is characterized in that the protecting layer has a hinge-like connection on two opposite edges to the supporting sheet.
摘要翻译： PCT No.PCT / EP97 / 06532 Sec。 371日期：1999年7月15日 102（e）日期1999年7月15日PCT 1997年11月21日PCT公布。公开号WO98 / 25521 日期1998年6月18日具有布置在背衬膜上的至少一个活性物质容器的补片测试膏具有由聚合物材料制成的高弹性背衬薄膜，对液体水不透水，但是可透过水蒸气，并且可释放地连接在面向皮肤的表面到支撑片材的表面上，并且在施加石膏之前，将粘合层设置在面向皮肤的表面上，该粘合剂层又由至少两部分的可拆卸保护层覆盖，其特征在于，保护层在与支撑片材相对的两个边缘上具有铰链状连接。

6. 发明授权

US5264224A Process for producing and administration and/or dosage form for medicinal active substances by means of a printing process 失效
标题翻译：和/或通过印刷方法的药用活性物质的剂型的方法
公开(公告)号：US5264224A
公开(公告)日：1993-11-23
申请号：US834483
申请日：1992-02-12
申请人： Dieter Anhauser , Robert-Peter Klein
发明人： Dieter Anhauser , Robert-Peter Klein
IPC分类号： A61K9/44 , A61J3/00 , A61J3/10 , A61K9/70 , A61K31/465 , B41F17/00 , B41F17/34 , B41M1/40
CPC分类号： A61K9/7084 , A61J3/10 , A61K9/70
摘要： The invention relates to a process for producing an administration and/or dosage form for medicament active substances using a printing process, in which the printing process used is a pad printing process.
摘要翻译：本发明涉及使用印刷方法制备药物活性物质的给药和/或剂型的方法，其中使用的印刷方法是移印工艺。

7. 发明授权

US5044372A Epicutaneous test plaster 失效
标题翻译：皮肤试验膏药
公开(公告)号：US5044372A
公开(公告)日：1991-09-03
申请号：US328089
申请日：1989-03-23
申请人： Dieter Anhauser , Kurt Seeger
发明人： Dieter Anhauser , Kurt Seeger
IPC分类号： G01N33/50 , A61B10/00 , A61F13/00 , A61F13/02 , A61K9/70
CPC分类号： A61K9/703 , A61B10/0035 , A61F13/023 , A61K9/7084 , A61F2013/00434 , A61F2013/008 , A61F2013/00829 , A61F2013/00868
摘要： The invention relates to plasters, particularly epicutaneous test plasters with at least one active substance absorbing or receiving device (14) arranged on a carrier film (32). The carrier film (12) is made from a highly elastic polymer material, which is impermeable for liquid water, but permeable for water vapour. On the surface remote from the skin, it is detachably connected in whole-area or partial area manner with a support film (11) at least covering the surface of the carrier film. The invention also relates to processes for the production thereof and the use thereof.
摘要翻译：本发明涉及膏药，特别是具有布置在载体膜（32）上的至少一种活性物质吸收或接收装置（14）的表皮试验膏药。载体膜（12）由高弹性聚合物材料制成，其对于液态水是不可渗透的，但是对于水蒸气是可渗透的。在远离皮肤的表面上，其可以以至少覆盖载体膜的表面的支撑膜（11）以全部或部分区域方式可拆卸地连接。本发明还涉及其生产方法及其用途。

8. 发明授权

US5681413A Production of transdermal therapeutic systems 失效
标题翻译：透皮治疗系统的生产
公开(公告)号：US5681413A
公开(公告)日：1997-10-28
申请号：US403754
申请日：1995-05-09
申请人： Thomas Hille , Lothar Deurer , Peter Steinborn , Ludwig Grader , Dieter Anhauser
发明人： Thomas Hille , Lothar Deurer , Peter Steinborn , Ludwig Grader , Dieter Anhauser
IPC分类号： B65C1/02 , A61F13/00 , A61F13/02 , A61K9/70 , A61L15/44 , A61L15/58 , A61M37/00 , B32B37/22
CPC分类号： B32B37/22 , A61K9/7061 , B32B38/1825 , A61F2013/0296 , B32B2309/14 , Y10T156/1062 , Y10T156/1093 , Y10T156/1335
摘要： The invention provides a process for the production of transdermal therapeutic systems. A layer containing active substance is initially present as a tape or web in the form of a laminate, with a carrier layer and, possibly, further auxiliary layers and/or protective layers or the like. The active substance is then transferred from this layer, either by itself or in combination with at least one further layer, in sections, to the center of a second, wider web. The process is characterized by the fact that the tape or web (1) and the second web (2) are moved forward by steps, with different phases of motion and inoperative phases and/or different step lengths and/or differing speeds and that in the same appliance, during each inoperative or stationary phase of the webs (1, 2) the subdivision of the layer containing active substance and, as the case may be, of one or more further layers, with the exception of the carrier layer, takes place in phases and in the same forward direction, at right angles to the direction of web, into sections (7, 8) containing active substance of a size suitable for the user, and their transfer to the second web, the carrier sheet (9) being removed, in preferably equal intervals, using a transfer device which can be moved backwards and forwards in the direction of the web.
摘要翻译： PCT No.PCT / EP93 / 02495 371日期1995年5月9日第 102（e）日期1995年5月9日PCT提交1993年9月15日PCT公布。公开号WO94 / 07449 日期1994年04月14日本发明提供了一种生产透皮治疗系统的方法。含有活性物质的层最初作为具有载体层和可能的其它辅助层和/或保护层等的叠层形式的带或网状物存在。然后将活性物质本身或与至少一个另外的层组合地从该层转移到第二较宽幅材的中心。该方法的特征在于，带或纤维网（1）和第二纤维网（2）通过不同的运动阶段和不同的步长和/或不同速度的步骤向前移动，并且在相同的器具，在幅材（1,2）的每个不活动或固定相期间，除了载体层之外，含有活性物质的层的细分（视情况而定）为一个或多个另外的层，将相位和相同的向前的方向放置在与卷筒纸的方向成直角的部分（7,8）中，该部分（7,8）包含适合使用者的尺寸的活性物质，并且它们转移到第二纤维网，载体片材）以优选相等的间隔使用能够在幅材的方向上向前和向前移动的转移装置被移除。

9. 发明授权

US5516395A Process for the production of collagen foams in the form of continuous tapes and their use in medicine, cosmetics and hygiene 失效
标题翻译：以连续胶带的形式生产胶原蛋白泡沫的方法及其在医药，化妆品和卫生中的应用
公开(公告)号：US5516395A
公开(公告)日：1996-05-14
申请号：US172403
申请日：1993-12-23
申请人： Dieter Anhauser , Michael Roreger
发明人： Dieter Anhauser , Michael Roreger
IPC分类号： A61K9/70 , A61K47/42 , A61L15/32 , A61L15/42 , C08J9/28 , B32B31/00
CPC分类号： C08J9/28 , A61K47/42 , A61K9/7007 , A61L15/325 , A61L15/425 , C08J2201/0484 , C08J2389/06 , Y10T156/1067 , Y10T82/10 , Y10T82/16967
摘要： The present invention relates to a process for the production of collagen foams in the form of continuous tapes, characterized in thata) solved or dispersed collagen is cast into disk molds,b) the collagen solution or dispersion is frozen in the disk mold and subsequently is freeze-driedc) continuous tapes are produced from the freeze-dried disks by mechanical processes. Furthermore, the present invention relates to the use of said tapes so obtained in medicine, cosmetic and hygiene.
摘要翻译：本发明涉及一种以连续带形式生产胶原蛋白泡沫的方法，其特征在于：a）将溶解或分散的胶原蛋白铸造到圆盘模具中，b）将胶原溶液或分散体冷冻在盘模具中，随后冷冻干燥c）通过机械过程从冷冻干燥的盘产生连续带。此外，本发明涉及在医药，化妆品和卫生学中如此获得的所述胶带的使用。

10. 发明授权

US5115913A Packaged supported pressure-sensitive adhesive plasters 失效
标题翻译：包装支持的压力敏感胶粘剂
公开(公告)号：US5115913A
公开(公告)日：1992-05-26
申请号：US543637
申请日：1990-06-26
申请人： Dieter Anhauser , Ralf Huhn
发明人： Dieter Anhauser , Ralf Huhn
IPC分类号： B65D75/52 , A61F13/02 , A61F15/00 , B05D5/10 , B65D57/00 , B65D75/54
CPC分类号： A61F15/001 , B65D75/54 , Y10S206/813
摘要： In combination, a bag, at least one active mass, and a support, the active mass being carried on the support within the bag and having an exposed pressure-sensitive adherent surface, the support carrying integral spacers which are laterally spaced from the active mass and project above the surface of the support a distance greater than the height of said active mass, thereby to space the mass from the bag.
摘要翻译：组合在一起的袋子，至少一个活性物质和载体，活性物质被承载在袋内的载体上并且具有暴露的压敏粘合表面，载体承载与活性物质横向隔开的整体间隔物并且在所述支撑体的表面上方突出大于所述活性物质的高度的距离，从而使质量与袋离开。

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