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1. 发明授权

US09125632B2 Systems and methods for cardiac remodeling 有权
标题翻译：心脏重塑的系统和方法
公开(公告)号：US09125632B2
公开(公告)日：2015-09-08
申请号：US12253792
申请日：2008-10-17
申请人： Didier Loulmet , Niel F. Starksen , Mariel Fabro , Eugene Serina
发明人： Didier Loulmet , Niel F. Starksen , Mariel Fabro , Eugene Serina
IPC分类号： A61F2/24 , A61B17/00 , A61B17/04 , A61B17/064
CPC分类号： A61B17/00234 , A61B17/0401 , A61B17/064 , A61B17/0644 , A61B2017/00243 , A61B2017/00783 , A61B2017/0414 , A61B2017/0496 , A61F2/2445 , A61F2/2481 , A61F2/2487
摘要： Described herein are devices and methods for improving the hemodynamic function of a patient. In particular, a first device adapted to reshape an atrio-ventricular valve is used in combination with a second device configured to further alter the blood flow through the valve. The first device is typically an implant positioned in the subvalvular space of a ventricle. The second device may be an annuloplasty implant, a non-annulus valve apparatus implant, a ventriculoplasty implant, or a cardiac rhythm management device.
摘要翻译：本文描述了用于改善患者的血液动力学功能的装置和方法。特别地，适于重新形成心室瓣膜的第一装置与被配置为进一步改变通过所述瓣膜的血液流动的第二装置组合使用。第一装置通常是定位在心室的瓣膜下空间的植入物。第二装置可以是瓣环成形植入物，非环形瓣膜装置植入物，心室成形术植入物或心律管理装置。

2. 发明授权

US08545551B2 Methods, devices, and kits for treating mitral valve prolapse 有权
公开(公告)号：US08545551B2
公开(公告)日：2013-10-01
申请号：US12608849
申请日：2009-10-29
申请人： Didier Loulmet
发明人： Didier Loulmet
IPC分类号： A61F2/24 , A61B17/08 , A61L17/00
CPC分类号： A61B17/320016 , A61B17/0401 , A61B2017/00243 , A61B2017/0412 , A61F2/2457
摘要： Described here are methods, devices, and kits for treating a prolapsed valve leaflet. The devices generally comprise a flexible cord, a first anchor attached to the cord at its distal end, and a second anchor slidably attached to the cord. The first anchor may be configured to secure the cord to cardiac tissue located below a prolapsed valve leaflet and the second anchor may be configured to secure into the prolapsed valve leaflet. Also described are methods for treating a prolapsed valve including the steps of securing a first anchor to cardiac tissue located below the prolapsed mitral valve leaflet, securing a second anchor to the prolapsed mitral valve leaflet, tensioning a cord connecting the two anchors and securing the cord. Kits including the described devices are also provided.

3. 发明申请

US20100049311A1 METHODS, DEVICES, AND KITS FOR TREATING MITRAL VALVE PROLAPSE 有权
标题翻译：用于治疗麻醉机的方法，装置和工具
公开(公告)号：US20100049311A1
公开(公告)日：2010-02-25
申请号：US12608849
申请日：2009-10-29
申请人： Didier Loulmet
发明人： Didier Loulmet
IPC分类号： A61F2/24
CPC分类号： A61B17/320016 , A61B17/0401 , A61B2017/00243 , A61B2017/0412 , A61F2/2457
摘要： Described here are methods, devices, and kits for treating a prolapsed valve leaflet. The devices generally comprise a flexible cord, a first anchor attached to the cord at its distal end, and a second anchor slidably attached to the cord. The first anchor may be configured to secure the cord to cardiac tissue located below a prolapsed valve leaflet and the second anchor may be configured to secure into the prolapsed valve leaflet. Also described are methods for treating a prolapsed valve including the steps of securing a first anchor to cardiac tissue located below the prolapsed mitral valve leaflet, securing a second anchor to the prolapsed mitral valve leaflet, tensioning a cord connecting the two anchors and securing the cord. Kits including the described devices are also provided.
摘要翻译：这里描述了用于治疗脱垂的瓣膜小叶的方法，装置和试剂盒。装置通常包括柔性绳索，在其远端处附接到绳索的第一锚固件和可滑动地附接到绳索的第二锚固件。第一锚固件可以被配置成将绳索固定在位于脱垂的瓣膜小叶下方的心脏组织上，并且第二锚固件可被构造成固定到脱垂的瓣膜小叶中。还描述了用于治疗脱垂的瓣膜的方法，包括以下步骤：将第一锚定固定在位于脱垂的二尖瓣小叶下方的心脏组织上，将第二锚固件固定到脱垂的二尖瓣小叶上，张紧连接两个锚的绳索并固定绳。还提供了包括所描述的装置的套件。

4. 发明申请

US20090234318A1 SYSTEMS AND METHODS FOR CARDIAC REMODELING 有权
标题翻译：心脏重塑的系统与方法
公开(公告)号：US20090234318A1
公开(公告)日：2009-09-17
申请号：US12253792
申请日：2008-10-17
申请人： Didier LOULMET , Niel F. Starksen , Mariel Fabro , Eugene Serina
发明人： Didier LOULMET , Niel F. Starksen , Mariel Fabro , Eugene Serina
IPC分类号： A61M31/00 , A61F2/24
CPC分类号： A61B17/00234 , A61B17/0401 , A61B17/064 , A61B17/0644 , A61B2017/00243 , A61B2017/00783 , A61B2017/0414 , A61B2017/0496 , A61F2/2445 , A61F2/2481 , A61F2/2487
摘要： Described herein are devices and methods for improving the hemodynamic function of a patient. In particular, a first device adapted to reshape an atrio-ventricular valve is used in combination with a second device configured to further alter the blood flow through the valve. The first device is typically an implant positioned in the subvalvular space of a ventricle. The second device may be an annuloplasty implant, a non-annulus valve apparatus implant, a ventriculoplasty implant, or a cardiac rhythm management device.
摘要翻译：本文描述了用于改善患者的血液动力学功能的装置和方法。特别地，适于重新形成心室瓣膜的第一装置与被配置为进一步改变通过所述瓣膜的血液流动的第二装置组合使用。第一装置通常是定位在心室的瓣膜下空间的植入物。第二装置可以是瓣环成形植入物，非环形瓣膜装置植入物，心室成形术植入物或心律管理装置。

5. 发明申请

US20110011917A1 METHODS, DEVICES, AND KITS FOR TREATING VALVE PROLAPSE 审中-公开
标题翻译：用于处理阀门的方法，装置和工具
公开(公告)号：US20110011917A1
公开(公告)日：2011-01-20
申请号：US12651287
申请日：2009-12-31
申请人： Didier Loulmet
发明人： Didier Loulmet
IPC分类号： A61B17/064
CPC分类号： A61B17/0401 , A61B17/0467 , A61B17/0686 , A61B17/07292 , A61B90/39 , A61B2017/00243 , A61B2017/003 , A61B2017/00535 , A61B2017/00783 , A61B2017/00867 , A61B2017/0409 , A61B2017/0414 , A61B2017/0417 , A61B2017/0419 , A61B2017/0437 , A61B2017/0445 , A61B2017/0464 , A61B2017/0496 , A61B2017/2927 , A61B2017/306 , A61F2/2457
摘要： Methods, devices, and kits are described for addressing cardiac valve repair. A system for deploying a tensile member between two tissue structures may comprise a first anchor insertion instrument defining a working lumen therethrough, and a second anchor insertion instrument movably coupled through the working lumen, wherein the first anchor instrument defines a jaw space and is configured to deploy a staple prosthesis into a portion of a first tissue structure which may be captured within the jaw space, and wherein the second anchor instrument is configured to deploy an implantable anchor, such as an anchor dart, into a second tissue structure which is coupled to the staple prosthesis by a tensile member, such as a suture.
摘要翻译：描述了用于解决心脏瓣膜修复的方法，装置和试剂盒。用于在两个组织结构之间展开拉伸构件的系统可以包括限定通过其中的工作腔的第一锚定插入器具和可移动地联接到工作腔的第二锚固件插入器械，其中第一锚固器具限定钳口空间，将缝合假体部署到第一组织结构的可以在钳夹空间内捕获的部分中，并且其中第二锚定器具被配置成将可植入的锚固件（例如锚定器飞镖）部署到第二组织结构中，所述第二组织结构耦合到通过拉伸构件例如缝合线的缝合假体。

6. 发明授权

US07632308B2 Methods, devices, and kits for treating mitral valve prolapse 有权
标题翻译：用于治疗二尖瓣脱垂的方法，装置和试剂盒
公开(公告)号：US07632308B2
公开(公告)日：2009-12-15
申请号：US11286037
申请日：2005-11-23
申请人： Didier Loulmet
发明人： Didier Loulmet
IPC分类号： A61F2/24 , A61F2/00 , A61F13/00
CPC分类号： A61B17/320016 , A61B17/0401 , A61B2017/00243 , A61B2017/0412 , A61F2/2457
摘要： Described here are methods, devices, and kits for treating a prolapsed valve leaflet. The devices generally comprise a flexible cord, a first anchor attached to the cord at its distal end, and a second anchor slidably attached to the cord. The first anchor may be configured to secure the cord to cardiac tissue located below a prolapsed valve leaflet and the second anchor may be configured to secure into the prolapsed valve leaflet. Also described are methods for treating a prolapsed valve including the steps of securing a first anchor to cardiac tissue located below the prolapsed mitral valve leaflet, securing a second anchor to the prolapsed mitral valve leaflet, tensioning a cord connecting the two anchors and securing the cord. Kits including the described devices are also provided.
摘要翻译：这里描述了用于治疗脱垂的瓣膜小叶的方法，装置和试剂盒。装置通常包括柔性绳索，在其远端处附接到绳索的第一锚固件和可滑动地附接到绳索的第二锚固件。第一锚固件可以被配置成将绳索固定在位于脱垂的瓣膜小叶下方的心脏组织上，并且第二锚固件可被构造成固定到脱垂的瓣膜小叶中。还描述了用于治疗脱垂的瓣膜的方法，包括以下步骤：将第一锚定固定在位于脱垂的二尖瓣小叶下方的心脏组织上，将第二锚固件固定到脱垂的二尖瓣小叶上，张紧连接两个锚的绳索并固定绳。还提供了包括所描述的装置的套件。

7. 发明申请

US20070118213A1 Methods, devices, and kits for treating mitral valve prolapse 有权
标题翻译：用于治疗二尖瓣脱垂的方法，装置和试剂盒
公开(公告)号：US20070118213A1
公开(公告)日：2007-05-24
申请号：US11286037
申请日：2005-11-23
申请人： Didier Loulmet
发明人： Didier Loulmet
IPC分类号： A61F2/24
CPC分类号： A61B17/320016 , A61B17/0401 , A61B2017/00243 , A61B2017/0412 , A61F2/2457
摘要： Described here are methods, devices, and kits for treating a prolapsed valve leaflet. The devices generally comprise a flexible cord, a first anchor attached to the cord at its distal end, and a second anchor slidably attached to the cord. The first anchor may be configured to secure the cord to cardiac tissue located below a prolapsed valve leaflet and the second anchor may be configured to secure into the prolapsed valve leaflet. Also described are methods for treating a prolapsed valve including the steps of securing a first anchor to cardiac tissue located below the prolapsed mitral valve leaflet, securing a second anchor to the prolapsed mitral valve leaflet, tensioning a cord connecting the two anchors and securing the cord. Kits including the described devices are also provided.
摘要翻译：这里描述了用于治疗脱垂的瓣膜小叶的方法，装置和试剂盒。装置通常包括柔性绳索，在其远端处附接到绳索的第一锚固件和可滑动地附接到绳索的第二锚固件。第一锚固件可以被配置成将绳索固定在位于脱垂的瓣膜小叶下方的心脏组织上，并且第二锚固件可被构造成固定到脱垂的瓣膜小叶中。还描述了用于治疗脱垂的瓣膜的方法，包括以下步骤：将第一锚定固定在位于脱垂的二尖瓣小叶下方的心脏组织上，将第二锚固件固定到脱垂的二尖瓣小叶上，张紧连接两个锚的绳索并固定绳。还提供了包括所描述的装置的套件。

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