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    • 2. 发明授权
    • Integrated fluorescence-based biochemical sensor
    • 综合荧光基生化传感器
    • US6024923A
    • 2000-02-15
    • US313466
    • 1999-05-17
    • Jose MelendezRichard A. CarrDiane Arbuthnot
    • Jose MelendezRichard A. CarrDiane Arbuthnot
    • G01N21/64G01N21/78
    • G01N21/645G01N21/6428G01N2201/022
    • An integrated biochemical sensor (200) for detecting the presence of one or more specific samples (240) having a device platform (355) with a light absorbing upper surface and input/output pins (375) is disclosed. An encapsulating housing (357) provides an optical transmissive enclosure which covers the platform (355) and has a layer of fluorescence chemistry on its outer surface (360). The fluorophore is chosen for its molecular properties in the presence of the sample analyte (240). The detector (370), light sources (365, 367, 407, 409) are all coupled to the platform (355) and encapsulated within the housing (357). A filter (375) element is used to block out unwanted light and increase the detector's (370) ability to resolve wanted emission light.
    • 公开了一种用于检测具有光吸收上表面和输入/输出销(375)的装置平台(355)的一个或多个特定样品(240)的存在的集成生物化学传感器(200)。 封装壳体(357)提供覆盖平台(355)并且在其外表面(360)上具有一层荧光化学物质的透光外壳。 在样品分析物(240)的存在下,选择荧光团的分子性质。 检测器(370),光源(365,367,407,409)都耦合到平台(355)并且封装在壳体(357)内。 滤光器(375)元件用于阻挡不需要的光,并增加检测器(370)解决所需发射光的能力。