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1. 发明授权

US5565360A Bioluminescent bioassay system 失效
标题翻译：生物发光生物测定系统
公开(公告)号：US5565360A
公开(公告)日：1996-10-15
申请号：US321066
申请日：1994-10-11
申请人： David Lapota , Gary F. Mastny , Hugh D. Copeland , Dena E. Rosenberger
发明人： David Lapota , Gary F. Mastny , Hugh D. Copeland , Dena E. Rosenberger
IPC分类号： G01N33/18 , G01N21/76
CPC分类号： G01N33/1866
摘要： A system for measuring toxicity levels of a solution includes a water proof sample container transparent to visible light which holds an aqueous test solution containing bioluminescent organisms. A light tight chamber has a cavity which holds the sample container and includes a light port. A stress generating system positioned in the sample container generates pressure pulses which stimulate the organisms to generate light emissions. A light detector system mounted to the light tight chamber in a light tight manner detects light emissions generated in the sample container which propagate through the light port and are received by the light detector system. The light detector system generates an electric pulse in response to detecting each detected light emission. A controller enables the stress generating system and the light detector system, and then counts the electric pulses within a predetermined period of time.
摘要翻译：用于测量溶液的毒性水平的系统包括对可见光透明的防水样品容器，其保持含有生物发光生物体的水性测试溶液。不透光室具有容纳样品容器并包括光口的空腔。位于样品容器中的应力产生系统产生刺激生物体产生光发射的压力脉冲。以不透光的方式安装到不透光室的光检测器系统检测在样品容器中产生的光，其通过光端口传播并被光检测器系统接收。光检测器系统响应于检测到每个检测到的光发射而产生电脉冲。控制器使能应力产生系统和光检测器系统，然后在预定的时间段内对电脉冲进行计数。

2. 发明授权

US5840572A Bioluminescent bioassay system 失效
标题翻译：生物发光生物测定系统
公开(公告)号：US5840572A
公开(公告)日：1998-11-24
申请号：US688133
申请日：1996-07-29
申请人： Hugh D. Copeland , David Lapota , Dena E. Rosenberger , Gary F. Mastny
发明人： Hugh D. Copeland , David Lapota , Dena E. Rosenberger , Gary F. Mastny
IPC分类号： G01N33/18 , C12M3/00
CPC分类号： G01N33/1866 , Y10S435/808
摘要： A system for measuring toxicity levels of a solution includes a water proof sample container transparent to visible light which holds an aqueous test solution containing bioluminescent organisms. A light tight chamber has a cavity which holds the sample container and includes a light port. A stress generating system positioned in the sample container generates pressure pulses which stimulate the organisms to generate light emissions. A light detector system mounted to the light tight chamber in a light tight manner detects light emissions generated in the sample container which propagate through the light port and are received by the light detector system. The light detector system generates an electric pulse in response to detecting each detected light emission. A controller enables the stress generating system and the light detector system, and then counts the electric pulses within a predetermined period of time. The system may further include a fiber optic bundle for propagating light from the light port to the photodetector element in the light detector system, and an optical attenuator supervised by the controller to limit the intensity of light irradiating the photodetector within the linear response range of the element, and to prevent ambient light from saturating and damaging the photodetector.
摘要翻译：用于测量溶液的毒性水平的系统包括对可见光透明的防水样品容器，其保持含有生物发光生物体的水性测试溶液。不透光室具有容纳样品容器并包括光口的空腔。位于样品容器中的应力产生系统产生刺激生物体产生光发射的压力脉冲。以不透光的方式安装到不透光室的光检测器系统检测在样品容器中产生的光，其通过光端口传播并被光检测器系统接收。光检测器系统响应于检测到每个检测到的光发射而产生电脉冲。控制器使能应力产生系统和光检测器系统，然后在预定的时间段内对电脉冲进行计数。该系统还可以包括用于将来自光端口的光传播到光检测器系统中的光电检测器元件的光纤束，以及由该控制器监控的光衰减器，用于将照射光电检测器的光的强度限制在该光检测器的线性响应范围内元件，并防止环境光饱和和损坏光电检测器。

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