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1. 发明授权

US5689895A Probe positioning device for a flask freeze drying 失效
标题翻译：探针定位装置用于烧瓶冷冻干燥
公开(公告)号：US5689895A
公开(公告)日：1997-11-25
申请号：US742259
申请日：1996-10-31
申请人： David T. Sutherland , Alan P. MacKenzie , Dean B. Wise
发明人： David T. Sutherland , Alan P. MacKenzie , Dean B. Wise
IPC分类号： F26B5/06 , F26B13/30
CPC分类号： F26B5/06
摘要： A device for positioning a probe, such as a temperature sensor, in a flask for freeze drying. The device includes a stopper adapted to be secured to an open end of the flask. The stopper has a center opening and at least one radial opening spaced from the center opening. The radial opening allows for fluid communication between inside and outside of the flask when the stopper is secured to the open end of the flask. The center opening receives a guide tube which extends into the flask and is sized to receive the probe such that substantially no fluid communication between the inside of the flask and the outside of the flask occurs through the guide tube or center opening. A channel formed in an upper surface of the stopper and an O-ring positioned about an outer diameter of a neck of the flask secure the probe in position relative to the guide tube. The multiple radial openings define an annular passageway which mimics fluid communication through a standard slit-type stopper employed in freeze drying.
摘要翻译：用于将诸如温度传感器的探针定位在用于冷冻干燥的烧瓶中的装置。该装置包括适于固定到烧瓶的开口端的塞子。止动件具有中心开口和与中心开口间隔开的至少一个径向开口。当止动器固定到烧瓶的开口端时，径向开口允许在烧瓶的内部和外部之间的流体连通。中心开口接收延伸到烧瓶中的导管，其尺寸设置成接收探针，使得烧瓶内部和烧瓶外部之间的流体连通通过导管或中心开口发生。形成在止动件的上表面中的通道和围绕烧瓶颈部的外径定位的O形环将探针相对于导管固定就位。多个径向开口限定了环形通道，其模拟通过用于冷冻干燥的标准狭缝型塞子的流体连通。

2. 发明授权

US5267790A Temperature-controlled homogenizer with sample gripper 失效
标题翻译：带样品夹具的温度控制均质器
公开(公告)号：US5267790A
公开(公告)日：1993-12-07
申请号：US846835
申请日：1992-03-06
申请人： David T. Sutherland , Siegfried G. Bart, Jr. , Douglas G. Wernerspach , Dean B. Wise , Anthony P. Montalbano , Christopher T. Montalbano , Douglas J. Hohlbein
发明人： David T. Sutherland , Siegfried G. Bart, Jr. , Douglas G. Wernerspach , Dean B. Wise , Anthony P. Montalbano , Christopher T. Montalbano , Douglas J. Hohlbein
IPC分类号： B01F7/16 , B01F15/00 , B01F15/06 , B01F13/04
CPC分类号： B01F15/06 , B01F15/00396 , B01F15/00746 , B01F7/161 , Y10S366/601
摘要： The present invention provides a high speed homogenizer which has an adjustable gripping means to grip and hold containers of varying size. This gripping and holding means can be centered or decentered under the homogenizing tool. Decentering a container held by the gripping and holding means tends to minimize or even eliminate vortexing problems. The homogenizer also has electronic means for controlling the speed and time of operation of the homogenizing tool. The electronic control means of the homogenizer can also monitor the temperature of the sample being homogenized and respond to changes in temperature when necessary. The homogenizer can be easily adjusted up and down a vertical support post by a counter weighting mechanism such as a constant force spring.
摘要翻译：本发明提供了一种高速均质器，其具有可调节的夹持装置，以夹持和保持不同尺寸的容器。该夹持和夹持装置可以在均质工具下居中或偏心。通过夹持和夹持装置固定的容器的倾析倾向于最小化甚至消除涡流问题。均化器还具有用于控制均质化工具的操作速度和时间的电子装置。均化器的电子控制装置还可以监测正在均质化的样品的温度，并在必要时对温度变化作出响应。均质器可以通过诸如恒力弹簧的反称重机构容易地上下调整垂直支撑柱。

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