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1. 发明授权

US08244564B2 Multi-strategy generation of product recommendations 有权
标题翻译：多策略生成产品推荐
公开(公告)号：US08244564B2
公开(公告)日：2012-08-14
申请号：US12415896
申请日：2009-03-31
申请人： David Lee Selinger , Michael James DeCourcey , Randall Stuart Fish , Bradley Ross Cerenzia , Tyler David Kohn , Darren Erik Vengroff
发明人： David Lee Selinger , Michael James DeCourcey , Randall Stuart Fish , Bradley Ross Cerenzia , Tyler David Kohn , Darren Erik Vengroff
IPC分类号： G06Q40/00
CPC分类号： G06Q30/0631 , G06Q30/02 , G06Q30/0601 , G06Q30/0643
摘要： Techniques are described for dynamically generating recommendations for users, such as for products and other items. In at least some situations, the techniques include using multiple recommendation strategies, such as by aggregating recommendation results from multiple different recommendation strategies. Such recommendation strategies may have various forms, and may be based at least in part on data regarding prior interactions of numerous users with numerous items. In addition, information about current selections of a particular user may be gathered based at least in part on providing a GUI (“graphical user interface”) for display to the user that includes selectable information about numerous recommended items, and dynamically updating the displayed GUI with newly generated recommendations of items as the user makes selections of particular displayed recommended items (e.g., newly generated recommendations that are similar to the selected items in one or more manners, or are otherwise related to the selected items).
摘要翻译：描述了用于为用户动态生成建议的技术，例如用于产品和其他项目。在至少一些情况下，这些技术包括使用多个推荐策略，例如通过聚合来自多个不同推荐策略的推荐结果。这样的推荐策略可以具有各种形式，并且可以至少部分地基于关于具有许多项目的许多用户的先前交互的数据。此外，可以至少部分地基于提供用于向用户显示的GUI（“图形用户界面”）来收集关于特定用户的当前选择的信息，所述GUI（包括图形用户界面）包括关于许多推荐项目的可选择的信息，并且动态地更新所显示的GUI 随着用户选择特定显示的推荐项目（例如，以一种或多种方式类似于所选项目的新生成的建议或者与所选项目相关），新产生的项目建议。

2. 发明申请

US20110152181A1 OXYNTOMODULIN PEPTIDE ANALOGUE 有权
标题翻译：氧自由基肽类似物
公开(公告)号：US20110152181A1
公开(公告)日：2011-06-23
申请号：US12968388
申请日：2010-12-15
申请人： Jorge ALSINA-FERNANDEZ , Wayne David KOHN
发明人： Jorge ALSINA-FERNANDEZ , Wayne David KOHN
IPC分类号： A61K38/22 , C07K14/575 , A61P3/04 , A61P3/10
CPC分类号： C07K14/575 , A61K38/00 , C07K14/605
摘要： The present invention provides Oxyntomodulin peptide analogues useful in the treatment of diabetes and/or obesity.
摘要翻译：本发明提供了可用于治疗糖尿病和/或肥胖症的胃泌酸调节蛋白肽类似物。

3. 发明申请

US20080300177A1 CYCLIC PEPTIDE CXCR4 ANTAGONISTS 有权
公开(公告)号：US20080300177A1
公开(公告)日：2008-12-04
申请号：US12123574
申请日：2008-05-20
申请人： Wayne David Kohn , Sheng-Bin Peng , Liang Zeng Yan
发明人： Wayne David Kohn , Sheng-Bin Peng , Liang Zeng Yan
IPC分类号： A61K38/12 , C07K7/64 , A61P35/00
CPC分类号： C07K7/54 , A61K38/00 , C07K7/56
摘要： Provided are lactam-cyclized peptide CXCR4 antagonists useful in the treatment of cancers, rheumatoid arthritis, pulmonary fibrosis, and HIV infection.
摘要翻译：提供可用于治疗癌症，类风湿性关节炎，肺纤维化和HIV感染的内酰胺环化肽CXCR4拮抗剂。

4. 发明申请

US20050247752A1 Surgical stapler having an aluminum head 审中-公开
标题翻译：具有铝头的手术吻合器
公开(公告)号：US20050247752A1
公开(公告)日：2005-11-10
申请号：US11130518
申请日：2005-05-17
申请人： William Kelly , Michael Kruszynski , Anthony Nguyen , Richard Schwemberger , David Kohn , Peter Wukusick , Sudhir Patel
发明人： William Kelly , Michael Kruszynski , Anthony Nguyen , Richard Schwemberger , David Kohn , Peter Wukusick , Sudhir Patel
IPC分类号： A61B17/04 , A61B17/068 , A61B17/072 , A61B17/10 , A61B17/28
CPC分类号： A61B17/072 , A61B2017/07221 , A61B2017/07271 , A61B2017/07285 , A61B2017/2927 , A61B2017/2946 , Y10T29/4984 , Y10T29/49888
摘要： A surgical instrument for applying a plurality of surgical fasteners to body tissue. The surgical instrument includes a frame having a handle at a proximal end thereof, and a support structure at a distal end thereof. The support structure adapted to support a plurality of surgical fasteners and is formed from aluminum.
摘要翻译：一种用于将多个外科紧固件应用于身体组织的手术器械。手术器械包括在其近端处具有手柄的框架，以及在其远端处的支撑结构。所述支撑结构适于支撑多个手术紧固件并且由铝形成。

5. 发明授权

US08415296B2 Oxyntomodulin peptide analogue 有权
标题翻译：胃泌酸调节蛋白肽类似物
公开(公告)号：US08415296B2
公开(公告)日：2013-04-09
申请号：US12968388
申请日：2010-12-15
申请人： Jorge Alsina-Fernandez , Wayne David Kohn
发明人： Jorge Alsina-Fernandez , Wayne David Kohn
IPC分类号： A61K38/22 , A61K38/26 , A61K38/28 , C07K14/575 , C07K7/00 , C07K16/00 , C07K17/00
CPC分类号： C07K14/575 , A61K38/00 , C07K14/605
摘要： The present invention provides Oxyntomodulin peptide analogues useful in the treatment of diabetes and/or obesity.
摘要翻译：本发明提供了可用于治疗糖尿病和/或肥胖症的胃泌酸调节蛋白肽类似物。

6. 再颁专利

USRE42274E1 Cyclic peptide CXCR4 antagonists 有权
标题翻译：环肽CXCR4拮抗剂
公开(公告)号：USRE42274E1
公开(公告)日：2011-04-05
申请号：US12807694
申请日：2010-09-10
申请人： Wayne David Kohn , Sheng-Bin Peng , Liang Zeng Yan
发明人： Wayne David Kohn , Sheng-Bin Peng , Liang Zeng Yan
IPC分类号： A61K38/12
CPC分类号： C07K7/54 , A61K38/00 , C07K7/56
摘要： Provided are lactam-cyclized peptide CXCR4 antagonists useful in the treatment of cancers, rheumatoid arthritis, pulmonary fibrosis, and HIV infection.
摘要翻译：提供可用于治疗癌症，类风湿性关节炎，肺纤维化和HIV感染的内酰胺环化肽CXCR4拮抗剂。

7. 发明申请

US20100130409A1 CYCLIC PEPTIDE CXCR4 ANTAGONISTS 审中-公开
公开(公告)号：US20100130409A1
公开(公告)日：2010-05-27
申请号：US12692788
申请日：2010-01-25
申请人： Wayne David Kohn , Sheng-Bin Peng , Liang Zeng Yan
发明人： Wayne David Kohn , Sheng-Bin Peng , Liang Zeng Yan
IPC分类号： A61K38/03 , C07K4/00 , A61P35/00 , A61P31/18
CPC分类号： C07K7/54 , A61K38/00 , C07K7/56
摘要： Provided are lactam-cyclized peptide CXCR4 antagonists useful in the treatment of cancers, rheumatoid arthritis, pulmonary fibrosis, and HIV infection.
摘要翻译：提供可用于治疗癌症，类风湿性关节炎，肺纤维化和HIV感染的内酰胺环化肽CXCR4拮抗剂。

8. 发明授权

US09215977B2 Portable device for indirect ophthalmology 有权
标题翻译：用于间接眼科的便携式装置
公开(公告)号：US09215977B2
公开(公告)日：2015-12-22
申请号：US13849552
申请日：2013-03-25
申请人： David Kohn Bitran
发明人： David Kohn Bitran
IPC分类号： A61B3/14 , A61B3/10 , A61B3/00
CPC分类号： A61B3/14 , A61B3/0025 , A61B3/0075
摘要： A device for examining an eye of a subject including a camera detachably mounted on a camera mounting unit. The camera includes an illuminating source, which generates illuminating radiation for irradiating the eye thereby enabling the camera to generate a plurality of images of the eye. The device also includes a first lens assembly detachably mounted on an adjustable lens holder and selected to focus the illuminating radiation towards the eye as well as focusing radiation reflected from the eye towards an entrance pupil of the camera. An extendible support arm supports the camera and the adjustable lens holder at a first distance between the camera and the first lens assembly. Subsequent to adjusting the first distance to correspond to a diopter value of the selected first lens assembly, the illuminating source irradiates the eye and subsequent thereto the camera generates the plurality of images of the eye.
摘要翻译：一种用于检查对象的眼睛的装置，包括可拆卸地安装在照相机安装单元上的照相机。相机包括照明源，其产生用于照射眼睛的照射辐射，从而使照相机能够生成眼睛的多个图像。该装置还包括可拆卸地安装在可调透镜架上并被选择以将照射辐射聚焦到眼睛以及将从眼睛反射的辐射聚焦到照相机的入射光瞳的第一透镜组件。可延伸的支撑臂在照相机和第一透镜组件之间的第一距离处支撑照相机和可调透镜保持器。在调整第一距离以对应于所选择的第一透镜组件的屈光度值之后，照明源照射眼睛，并且随后照相机产生眼睛的多个图像。

9. 发明申请

US20140285766A1 PORTABLE DEVICE FOR INDIRECT OPHTHALMOLOGY 审中-公开
标题翻译：便携式器械用于间接性眼科
公开(公告)号：US20140285766A1
公开(公告)日：2014-09-25
申请号：US13849552
申请日：2013-03-25
申请人： David KOHN BITRAN
发明人： David KOHN BITRAN
IPC分类号： A61B3/14 , A61B3/00
CPC分类号： A61B3/14 , A61B3/0025 , A61B3/0075
摘要： A device for examining at least one selected portion of an eye of a subject and including a camera detachably mounted on a camera mounting unit. The camera includes an illuminating source, which generates illuminating radiation for irradiating the at least one portion of the eye thereby enabling the camera to generate a plurality of images of the at least one portion of the eye. The device also includes a first lens assembly detachably mounted on an adjustable lens holder and selected to focus the illuminating radiation towards the at least one portion of the eye as well as focusing radiation reflected from the at least one portion of the eye towards an entrance pupil of the camera. An extendible support arm supports the camera and the adjustable lens holder at a first distance between the camera and the first lens assembly. Subsequent to adjusting the first distance to correspond to a diopter value of the selected first lens assembly, the illuminating source irradiates the at least one portion of the eye and subsequent thereto the camera generates the plurality of images of the at least one portion of the eye.
摘要翻译：一种用于检查对象的眼睛的至少一个选定部分并且包括可拆卸地安装在相机安装单元上的相机的装置。相机包括照明源，其产生用于照射眼睛的至少一部分的照明辐射，从而使照相机能够产生眼睛的至少一部分的多个图像。该装置还包括第一透镜组件，其可拆卸地安装在可调透镜保持器上并被选择以将照射辐射朝向眼睛的至少一部分聚焦，以及从眼睛的至少一部分反射的聚焦辐射朝向入射光瞳的相机。可延伸的支撑臂在照相机和第一透镜组件之间的第一距离处支撑照相机和可调透镜保持器。在调整第一距离以对应于所选择的第一透镜组件的屈光度值之后，照明源照射眼睛的至少一部分，并且随后照相机产生眼睛的至少一部分的多个图像。

10. 发明授权

US08367607B2 Oxyntomodulin peptide analogue 有权
标题翻译：胃泌酸调节蛋白肽类似物
公开(公告)号：US08367607B2
公开(公告)日：2013-02-05
申请号：US12968382
申请日：2010-12-15
申请人： Jorge Alsina-Fernandez , Wayne David Kohn
发明人： Jorge Alsina-Fernandez , Wayne David Kohn
IPC分类号： A61K38/22 , A61K38/26 , A61K38/28 , A61P3/10 , A61P7/12 , C07K14/605 , C07K5/00 , C07K7/00 , C07K16/00 , C07K17/00
CPC分类号： C07K14/605 , A61K38/00
摘要： The present invention provides an Oxyntomodulin peptide analogue useful in the treatment of diabetes and/or obesity.
摘要翻译：本发明提供了一种可用于治疗糖尿病和/或肥胖症的羟基调节蛋白肽类似物。

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